Experts and Doctors on membrane microdomains in Berlin, Germany


Locale: Berlin, Germany
Topic: membrane microdomains

Top Publications

  1. Dölle S, Hoser D, Rasche C, Loddenkemper C, Maurer M, Zuberbier T, et al. Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis. Allergy. 2010;65:1158-65 pubmed publisher
    ..Moreover, the increased frequency of FoxP3(+) cells in the skin of patients with AD suggests its immunomodulatory properties. ..
  2. Veit M, Engel S, Thaa B, Scolari S, Herrmann A. Lipid domain association of influenza virus proteins detected by dynamic fluorescence microscopy techniques. Cell Microbiol. 2013;15:179-89 pubmed publisher
    ..Finally, it is described how the signals that govern domain association in transfected cells affect replication of influenza virus. ..
  3. Liesche J, He H, Grimm B, Schulz A, Kuhn C. Recycling of Solanum sucrose transporters expressed in yeast, tobacco, and in mature phloem sieve elements. Mol Plant. 2010;3:1064-74 pubmed publisher
    ..The results provide new insight into the regulation of sucrose transport and the mechanism of endocytosis in plant cells. ..
  4. Rüdiger S, Jung P, Shuai J. Termination of Ca²+ release for clustered IP?R channels. PLoS Comput Biol. 2012;8:e1002485 pubmed publisher
    ..Thus our analysis hints at an additional role of IP3 and shows how cells can make use of the full complexity in IP?R gating behavior to achieve different signals. ..
  5. Welker P, Böhlick A, Mutig K, Salanova M, Kahl T, Schluter H, et al. Renal Na+-K+-Cl- cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent. Am J Physiol Renal Physiol. 2008;295:F789-802 pubmed publisher
    ..Results are consistent with a model in which LR mediate polar insertion, activity, and AVP-induced trafficking of NKCC2 in the control of transepithelial NaCl transport. ..
  6. Treppmann P, Brunk I, Afube T, Richter K, Ahnert Hilger G. Neurotoxic phospholipases directly affect synaptic vesicle function. J Neurochem. 2011;117:757-64 pubmed publisher
    ..SPANs and Ca(2+) dissociate the Syp/Syb complex as a prerequisite for exocytosis. SPANs also prevent the filling of synaptic vesicles thereby adding to the inhibition of neurotransmission. ..
  7. Dathe C, Daigeler A, Seifert W, Jankowski V, Mrowka R, Kalis R, et al. Annexin A2 mediates apical trafficking of renal Na?-K?-2Cl? cotransporter. J Biol Chem. 2014;289:9983-97 pubmed publisher
    ..In summary, this study identifies AnxA2 as a lipid raft-associated trafficking factor for NKCC2 and provides mechanistic insight into the regulation of this essential cotransporter. ..
  8. Wunder C, Churin Y, Winau F, Warnecke D, Vieth M, Lindner B, et al. Cholesterol glucosylation promotes immune evasion by Helicobacter pylori. Nat Med. 2006;12:1030-8 pubmed
    ..Thus, we propose a mechanism regulating the host-pathogen interaction whereby glucosylation of a lipid tips the scales towards immune evasion or response. ..
  9. Welker P, Geist B, Frühauf J, Salanova M, Groneberg D, Krause E, et al. Role of lipid rafts in membrane delivery of renal epithelial Na+-K+-ATPase, thick ascending limb. Am J Physiol Regul Integr Comp Physiol. 2007;292:R1328-37 pubmed
    ..These results may have functional implications regarding the turnover, trafficking, and regulated surface expression of NKA as the major basolateral ion transporter of TAL. ..

More Information


  1. Nikolaus J, Scolari S, Bayraktarov E, Jungnick N, Engel S, Pia Plazzo A, et al. Hemagglutinin of influenza virus partitions into the nonraft domain of model membranes. Biophys J. 2010;99:489-98 pubmed publisher
  2. Sanchez Ruderisch H, Detjen K, Welzel M, Andre S, Fischer C, Gabius H, et al. Galectin-1 sensitizes carcinoma cells to anoikis via the fibronectin receptor ?5?1-integrin. Cell Death Differ. 2011;18:806-16 pubmed publisher
    ..We propose that Gal-1/?(5)?(1)-integrin interaction participates in the control of epithelial integrity and integrin sialylation may enable carcinoma cells to evade this Gal-1-dependent control mechanism. ..
  3. Thaa B, Siche S, Herrmann A, Veit M. Acylation and cholesterol binding are not required for targeting of influenza A virus M2 protein to the hemagglutinin-defined budozone. FEBS Lett. 2014;588:1031-6 pubmed publisher
    ..The motifs are thus irrelevant for M2 targeting in cells. ..
  4. Bobone S, Hilsch M, Storm J, Dunsing V, Herrmann A, Chiantia S. Phosphatidylserine Lateral Organization Influences the Interaction of Influenza Virus Matrix Protein 1 with Lipid Membranes. J Virol. 2017;91: pubmed publisher
    ..Furthermore, the spatial organization of PS in the plane of the bilayer modulates M1-M1 interactions. Finally, we show that PS domains appear to be present in the PM of living cells and that M1 seems to display a high affinity for them. ..