Experts and Doctors on heme in Berlin, Germany
Locale: Berlin, Germany
Czarnecki O, Peter E, Grimm B. Methods for analysis of photosynthetic pigments and steady-state levels of intermediates of tetrapyrrole biosynthesis. Methods Mol Biol. 2011;775:357-85 pubmed publisher
..Although adjusted for Arabidopsis tetrapyrrole metabolites, the presented methods can also be applied for analysis of cyanobacterial and other plant tetrapyrroles. ..
Kemmner W, Wan K, Rüttinger S, Ebert B, Macdonald R, Klamm U, et al
. Silencing of human ferrochelatase causes abundant protoporphyrin-IX accumulation in colon cancer. FASEB J. 2008;22:500-9 pubmed
..Furthermore, accumulation of intracellular PpIX because of FECH siRNA silencing provides a small-molecule-based approach to molecular imaging and molecular therapy. ..
Shalygo N, Czarnecki O, Peter E, Grimm B. Expression of chlorophyll synthase is also involved in feedback-control of chlorophyll biosynthesis. Plant Mol Biol. 2009;71:425-36 pubmed publisher
..Chlorophyll synthase is proposed to be important for the co-regulation of the entire pathway and the coordination of synthesis of chlorophyll and the chlorophyll-binding proteins...
Seeber F, Soldati Favre D. Metabolic pathways in the apicoplast of apicomplexa. Int Rev Cell Mol Biol. 2010;281:161-228 pubmed publisher
..Finally, we highlight some aspects that emerged from recent publications and were not discussed previously with regard to Apicomplexa...
Czarnecki O, Hedtke B, Melzer M, Rothbart M, Richter A, Schr ter Y, et al
. An Arabidopsis GluTR binding protein mediates spatial separation of 5-aminolevulinic acid synthesis in chloroplasts. Plant Cell. 2011;23:4476-91 pubmed publisher
..These results regarding GluTRBP support a model of plant ALA synthesis that is organized in two separate ALA pools in the chloroplast to provide appropriate substrate amounts for balanced synthesis of heme and chlorophyll...
Lee H, Mochizuki N, Masuda T, Buckhout T. Disrupting the bimolecular binding of the haem-binding protein 5 (AtHBP5) to haem oxygenase 1 (HY1) leads to oxidative stress in Arabidopsis. J Exp Bot. 2012;63:5967-78 pubmed publisher
..It is proposed that the interaction between the HY1 and AtHBP5 proteins participate in an antioxidant pathway that might be mediated by reaction products of haem catabolism. ..