Experts and Doctors on viral gene expression regulation in Würzburg, Bavaria, Germany

Summary

Locale: Würzburg, Bavaria, Germany
Topic: viral gene expression regulation

Top Publications

  1. Ziebuhr J, Snijder E, Gorbalenya A. Virus-encoded proteinases and proteolytic processing in the Nidovirales. J Gen Virol. 2000;81:853-79 pubmed publisher
  2. Thiel V, Ivanov K, Putics A, Hertzig T, Schelle B, Bayer S, et al. Mechanisms and enzymes involved in SARS coronavirus genome expression. J Gen Virol. 2003;84:2305-15 pubmed
    ..The availability of recombinant forms of key replicative enzymes of SARS coronavirus should pave the way for high-throughput screening approaches to identify candidate inhibitors in compound libraries. ..
  3. Jurak I, Brune W. Induction of apoptosis limits cytomegalovirus cross-species infection. EMBO J. 2006;25:2634-42 pubmed
    ..Moreover, the same principle facilitates replication of the rat cytomegalovirus in human cells. Thus, induction of apoptosis serves as an innate immune defense to inhibit cross-species infections of rodent CMVs...
  4. Reuter T, Weissbrich B, Schneider Schaulies S, Schneider Schaulies J. RNA interference with measles virus N, P, and L mRNAs efficiently prevents and with matrix protein mRNA enhances viral transcription. J Virol. 2006;80:5951-7 pubmed publisher
    ..5 so that the genome-to-mRNA ratio was constant. These findings indicate that M acts as a negative regulator of viral polymerase activity, affecting mRNA transcription and genome replication to the same extent...