Experts and Doctors on dna in Nantes, Pays de la Loire, France

Summary

Locale: Nantes, Pays de la Loire, France
Topic: dna

Top Publications

  1. Ronsin C, Muscatelli F, Mattei M, Breathnach R. A novel putative receptor protein tyrosine kinase of the met family. Oncogene. 1993;8:1195-202 pubmed
    ..Interestingly, normal lung tissue contains transcripts of the RON gene. ..
  2. Le Caignec C, Lefevre M, Schott J, Chaventre A, Gayet M, Calais C, et al. Familial deafness, congenital heart defects, and posterior embryotoxon caused by cysteine substitution in the first epidermal-growth-factor-like domain of jagged 1. Am J Hum Genet. 2002;71:180-6 pubmed
  3. Desigaux L, Belkacem M, Richard P, Cellier J, Leone P, Cario L, et al. Self-assembly and characterization of layered double hydroxide/DNA hybrids. Nano Lett. 2006;6:199-204 pubmed
    ..96 nm. Our results indicate that labile complexes resulting from the association of nucleic acids and inorganic materials can be obtained not only by anion exchange but also by a direct self-assembly route...
  4. Do H, Nazih H, Luc G, Arveiler D, Ferrieres J, Evans A, et al. Influence of cholesteryl ester transfer protein, peroxisome proliferator-activated receptor alpha, apolipoprotein E, and apolipoprotein A-I polymorphisms on high-density lipoprotein cholesterol, apolipoprotein A-I, lipoprotein A-I, and lipoprotein A-. Metabolism. 2009;58:283-9 pubmed publisher
    ..The effect of the CETP A373P rare allele c on HDL-C was independent of all tested parameters except triglycerides. The respective effect of these polymorphisms and triglycerides on cardiovascular risk should be evaluated prospectively. ..
  5. Sevin M, Kutalik Z, Bergman S, Vercelletto M, Renou P, Lamy E, et al. Penetrance of marked cognitive impairment in older male carriers of the FMR1 gene premutation. J Med Genet. 2009;46:818-24 pubmed publisher
    ..In addition, it was observed that cognitive impairment may precede motor symptoms. These data provide guidance for genetic counselling although larger samples are required to refine these estimates. ..
  6. Chateigner Boutin A, Small I. Organellar RNA editing. Wiley Interdiscip Rev RNA. 2011;2:493-506 pubmed publisher
    ..Additional functions of editing in generating protein diversity or regulating gene expression have been proposed but so far lack widespread experimental evidence, at least in organelles...
  7. Menoret S, Fontanière S, Jantz D, Tesson L, Thinard R, Rémy S, et al. Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases. FASEB J. 2013;27:703-11 pubmed publisher
    ..Moreover, we generated an immunodeficient rat line useful for studies in which there is a need for biological parameters to be analyzed in the absence of immune responses. ..
  8. Chadeneau C, LeMoullac B, Denis M. Cloning and analysis of the human S13 ribosomal protein cDNA. Nucleic Acids Res. 1993;21:2945 pubmed
  9. Davodeau F, Houde I, Boulot G, Romagne F, Necker A, Canavo N, et al. Secretion of disulfide-linked human T-cell receptor gamma delta heterodimers. J Biol Chem. 1993;268:15455-60 pubmed
    ..Finally, the gamma delta heterodimer remains stable even after removal of the interchain disulfide link, suggesting the existence of strong noncovalent forces holding the two chains together. ..

More Information

Publications15

  1. Chadeneau C, LeMoullac B, LeCabellec M, Mattei M, Meflah K, Denis M. Isolation and chromosomal location of mE4, a novel murine gene of the immunoglobulin superfamily. Mamm Genome. 1996;7:636-7 pubmed
  2. Chipoy C, Berreur M, Couillaud S, Pradal G, Vallette F, Colombeix C, et al. Downregulation of osteoblast markers and induction of the glial fibrillary acidic protein by oncostatin M in osteosarcoma cells require PKCdelta and STAT3. J Bone Miner Res. 2004;19:1850-61 pubmed
    ..Together with the implication of PKCdelta, ERK1/2, and STAT3, these results offer new lines of investigations for neural cell transplantation and osteosarcoma therapy. ..
  3. Barc J, Briec F, Schmitt S, Kyndt F, Le Cunff M, Baron E, et al. Screening for copy number variation in genes associated with the long QT syndrome: clinical relevance. J Am Coll Cardiol. 2011;57:40-7 pubmed publisher
    ..Thus, we propose that CNV screening in KCNQ1 and KCNH2 may be performed routinely in LQTS patients. ..
  4. Isidor B, Lindenbaum P, Pichon O, Bezieau S, Dina C, Jacquemont S, et al. Truncating mutations in the last exon of NOTCH2 cause a rare skeletal disorder with osteoporosis. Nat Genet. 2011;43:306-8 pubmed publisher
    ..All mutations cluster to the last coding exon of the gene, suggesting that the mutant mRNA products escape nonsense-mediated decay and that the resulting truncated NOTCH2 proteins act in a gain-of-function manner. ..
  5. Alsaleh A, Pellerin J, Rodolakis A, Larrat M, Cochonneau D, Bruyas J, et al. Detection of Coxiella burnetii, the agent of Q fever, in oviducts and uterine flushing media and in genital tract tissues of the non pregnant goat. Comp Immunol Microbiol Infect Dis. 2011;34:355-60 pubmed publisher
    ..The infection of genital tract flushing media and tissues is a risk factor for the transmission of C. burnetii from donor to recipient during embryo transfer or to the embryo and fetus when gestation is pursued to term...
  6. Seki A, Ishikawa T, Daumy X, Mishima H, Barc J, Sasaki R, et al. Progressive Atrial Conduction Defects Associated With Bone Malformation Caused by a Connexin-45 Mutation. J Am Coll Cardiol. 2017;70:358-370 pubmed publisher
    ..Altogether, the authors showed that Cx45 mutant p.R75H is responsible for a novel disease entity of progressive atrial conduction system defects associated with craniofacial and dentodigital malformation. ..