Experts and Doctors on molecular sequence data in Lille, Nord Pas de Calais Picardie, France


Locale: Lille, Nord Pas de Calais Picardie, France
Topic: molecular sequence data

Top Publications

  1. Sebbane F, Bury Moné S, Cailliau K, Browaeys Poly E, De Reuse H, Simonet M. The Yersinia pseudotuberculosis Yut protein, a new type of urea transporter homologous to eukaryotic channels and functionally interchangeable in vitro with the Helicobacter pylori UreI protein. Mol Microbiol. 2002;45:1165-74 pubmed
    ..The Y. pseudotuberculosis Yut protein is therefore the first member of a novel class of bacterial urea permeases related to eukaryotic transporters. ..
  2. Bailly C, Tardy C, Wang L, Armitage B, Hopkins K, Kumar A, et al. Recognition of ATGA sequences by the unfused aromatic dication DB293 forming stacked dimers in the DNA minor groove. Biochemistry. 2001;40:9770-9 pubmed
    ..The data provide clues for delineating a recognition code for diamidine-type minor groove binding agents, and ultimately to guide the rational design of gene regulatory molecules targeted to specific sites of the genetic material. ..
  3. Supply P, Marceau M, Mangenot S, Roche D, Rouanet C, Khanna V, et al. Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis. Nat Genet. 2013;45:172-9 pubmed publisher
    ..tuberculosis. We conclude that M. tuberculosis emerged from an ancestral STB-like pool of mycobacteria by gain of persistence and virulence mechanisms, and we provide insights into the molecular events involved. ..
  4. Barthélemy N, Fenaille F, Hirtz C, Sergeant N, Schraen Maschke S, Vialaret J, et al. Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity. J Proteome Res. 2016;15:667-76 pubmed publisher
    ..This MS-based strategy provided results complementary to those of previous ELISA or Western Blot studies of CSF tau and could be applied to tau monitoring in human CSF cohorts. ..
  5. Bonnelye E, Vanacker J, Desbiens X, Begue A, Stehelin D, Laudet V. Rev-erb beta, a new member of the nuclear receptor superfamily, is expressed in the nervous system during chicken development. Cell Growth Differ. 1994;5:1357-65 pubmed
    ..We propose that Rev-erb beta may play an important role in the complex network of inductive signals, which control neuron differentiation. ..
  6. Danesi P, Da Rold G, Rizzoli A, Hauffe H, Marangon S, Samerpitak K, et al. Barcoding markers for Pneumocystis species in wildlife. Fungal Biol. 2016;120:191-206 pubmed publisher
    ..Nuclear rDNA ITS data confirmed unambiguous separation of species. In conclusion, ITS is an excellent marker to distinguish species of the genus Pneumocystis. ..
  7. Lebrun P, Raze D, Fritzinger B, Wieruszeski J, Biet F, Dose A, et al. Differential contribution of the repeats to heparin binding of HBHA, a major adhesin of Mycobacterium tuberculosis. PLoS ONE. 2012;7:e32421 pubmed publisher
    ..Further studies will aim at decoding the complementarity between HBD repeats and HS sequence. ..
  8. Glineur C, Zenke M, Beug H, Ghysdael J. Phosphorylation of the v-erbA protein is required for its function as an oncogene. Genes Dev. 1990;4:1663-76 pubmed
    ..These results support the hypothesis that phosphorylation of the gag/v-erbA protein is important for transcriptional repression of at least some of its target genes in erythroid cells. ..
  9. Popescu C, Callens N, Trinel D, Roingeard P, Moradpour D, Descamps V, et al. NS2 protein of hepatitis C virus interacts with structural and non-structural proteins towards virus assembly. PLoS Pathog. 2011;7:e1001278 pubmed publisher
    ..Together, these observations indicate that NS2 protein attracts the envelope proteins at the assembly site and it crosstalks with non-structural proteins for virus assembly. ..

More Information


  1. Collyn d Hooghe M, Galiegue Zouitina S, Szymiczek D, Lantoine D, Quief S, Loucheux Lefebvre M, et al. Quantitative and qualitative variation of ETS-1 transcripts in hematologic malignancies. Leukemia. 1993;7:1777-85 pubmed
  2. Follet J, Guyot K, Leruste H, Follet Dumoulin A, Hammouma Ghelboun O, Certad G, et al. Cryptosporidium infection in a veal calf cohort in France: molecular characterization of species in a longitudinal study. Vet Res. 2011;42:116 pubmed publisher
    ..C. parvum gp60 genotyping identifies 6 IIa subtypes of which 74.5% were represented by IIaA15G2R1. This work confirms previous studies in other countries showing that zoonotic C. parvum is the dominant species seen in young calves...
  3. Lécolle K, Begard S, Caillierez R, Demeyer D, Grellier E, Loyens A, et al. Sstr2A: a relevant target for the delivery of genes into human glioblastoma cells using fiber-modified adenoviral vectors. Gene Ther. 2013;20:283-97 pubmed publisher
    ..Adenoviral vectors targeting SRIF receptors might thus represent a promising therapeutic approach to brain tumors. ..
  4. Baeza Garcia A, Pierce R, Gourbal B, Werkmeister E, Colinet D, Reichhart J, et al. Involvement of the cytokine MIF in the snail host immune response to the parasite Schistosoma mansoni. PLoS Pathog. 2010;6:e1001115 pubmed publisher
    ..These results provide the first functional evidence that a MIF ortholog is involved in an invertebrate immune response towards a parasitic infection and highlight the importance of cytokines in invertebrate-parasite interactions. ..
  5. Grevin D, Ung S, Denhez F, Dehem M, Quatannens B, Begue A, et al. Structure and organization of the mouse elk1 gene. Gene. 1996;174:185-8 pubmed
    ..This information will be useful to engineer targeted mutations of this gene in mice and to determine the genomic structure of the other TCF genes. ..
  6. Hilbert L, Gaucher C, Mazurier C. Effects of different amino-acid substitutions in the leucine 694-proline 708 segment of recombinant von Willebrand factor. Br J Haematol. 1995;91:983-90 pubmed
    ..We show that the two mutations located in the loop are more reactive than the two mutations identified outside the loop. ..
  7. Daher W, Pierrot C, Kalamou H, Pinder J, Margos G, Dive D, et al. Plasmodium falciparum dynein light chain 1 interacts with actin/myosin during blood stage development. J Biol Chem. 2010;285:20180-91 pubmed publisher
    ..Taken together, these findings suggest that PfDLC1 might play an important role in P. falciparum erythrocytic stages by its interaction with myosin A and actin 1, known to be essential for parasite development. ..
  8. Rocha Perugini V, Montpellier C, Delgrange D, Wychowski C, Helle F, Pillez A, et al. The CD81 partner EWI-2wint inhibits hepatitis C virus entry. PLoS ONE. 2008;3:e1866 pubmed publisher
    ..This is the first example of a pathogen gaining entry into host cells that lack a specific inhibitory factor. ..
  9. Sebbane F, Devalckenaere A, Foulon J, Carniel E, Simonet M. Silencing and reactivation of urease in Yersinia pestis is determined by one G residue at a specific position in the ureD gene. Infect Immun. 2001;69:170-6 pubmed publisher
    ..Altogether our results demonstrate that variation of one extra G residue in ureD determines the ureolytic activity of Y. pestis but does not affect its virulence for mice or its ability to multiply and disseminate...
  10. Laudet V, Stehelin D, Clevers H. Ancestry and diversity of the HMG box superfamily. Nucleic Acids Res. 1993;21:2493-501 pubmed
    ..Finally, we provide a tree for the highly complex group of SRY-like ('Sox' genes), clustering at least 40 different loci that rapidly diverged in various animal lineages. ..
  11. Hervé M, Angeli V, Pinzar E, Wintjens R, Faveeuw C, Narumiya S, et al. Pivotal roles of the parasite PGD2 synthase and of the host D prostanoid receptor 1 in schistosome immune evasion. Eur J Immunol. 2003;33:2764-72 pubmed
    ..We also suggest that DP1 is important in the Th1/Th2 balance of the immune response and in inflammatory reactions during infection. ..
  12. Tulasne D, Deheuninck J, Lourenco F, Lamballe F, Ji Z, Leroy C, et al. Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage. Mol Cell Biol. 2004;24:10328-39 pubmed
    ..Finally, HGF/SF treatment does not favor MET cleavage and apoptosis, confirming the known survival role of ligand-activated MET. Our results show that stress stimuli convert the MET survival receptor into a proapoptotic factor. ..
  13. Neutelings G, Fenart S, Lucau Danila A, Hawkins S. Identification and characterization of miRNAs and their potential targets in flax. J Plant Physiol. 2012;169:1754-66 pubmed publisher
  14. Pancre V, Pierce R, Fournier F, Mehtali M, Delanoye A, Capron A, et al. Effect of ubiquitin on platelet functions: possible identity with platelet activity suppressive lymphokine (PASL). Eur J Immunol. 1991;21:2735-41 pubmed
    ..This molecule and PASL share several similarities in their functional and physicochemical properties. PASL could therefore belong to the family of ubiquitins. ..
  15. Audie J, Janin A, Porchet N, Copin M, Gosselin B, Aubert J. Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization. J Histochem Cytochem. 1993;41:1479-85 pubmed
    ..The choice of oligonucleotide probes was made to amplify the signal by hybridization of many small probes on the same mRNA molecules. A characteristic pattern of mucin gene expression was observed for each mucosa. ..
  16. Soichot M, Hennart B, Al Saabi A, Leloire A, Froguel P, Levy Marchal C, et al. Identification of a variable number of tandem repeats polymorphism and characterization of LEF-1 response elements in the promoter of the IDO1 gene. PLoS ONE. 2011;6:e25470 pubmed publisher
    ..These data offer new insights, and suggest further studies, into the role of IDO in various pathological conditions, particularly in cancer where IDO and the Wnt pathway are strongly dysregulated. ..
  17. Dufosse J, Porchet N, Audie J, Guyonnet Duperat V, Laine A, Van Seuningen I, et al. Degenerate 87-base-pair tandem repeats create hydrophilic/hydrophobic alternating domains in human mucin peptides mapped to 11p15. Biochem J. 1993;293 ( Pt 2):329-37 pubmed
    ..The mRNAs are expressed both in the respiratory and in the digestive tracts. These human mucin probes may be important in assessing the abnormal mucins associated with inflammatory diseases or carcinoma from human mucosae. ..
  18. Guyonnet Duperat V, Audie J, Debailleul V, Laine A, Buisine M, Galiegue Zouitina S, et al. Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes?. Biochem J. 1995;305 ( Pt 1):211-9 pubmed
    ..The functional significance for secreted mucins of these cysteine-rich subdomains and the modular organization of mucin peptides are discussed. ..
  19. Furman C, Rundlöf A, Larigauderie G, Jaye M, Bricca G, Copin C, et al. Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins. Free Radic Biol Med. 2004;37:71-85 pubmed
  20. Meunier I, Lenaers G, Bocquet B, Baudoin C, Piro Megy C, Cubizolle A, et al. A dominant mutation in MAPKAPK3, an actor of p38 signaling pathway, causes a new retinal dystrophy involving Bruch's membrane and retinal pigment epithelium. Hum Mol Genet. 2016;25:916-26 pubmed publisher
    ..These findings shed new lights on Bruch's membrane/RPE pathophysiology and will open studies of this signaling pathway in diseases with RPE and Bruch's membrane alterations, such as age-related macular degeneration. ..
  21. Mantini C, Souppart L, Noël C, Duong T, Mornet M, Carroger G, et al. Molecular characterization of a new Tetratrichomonas species in a patient with empyema. J Clin Microbiol. 2009;47:2336-9 pubmed publisher
    ..This observation raised the questions of the real prevalence of pulmonary trichomonosis in humans, the zoonotic potential of trichomonads, and the existence of human-host-adapted strains...
  22. Van Rechem C, Rood B, Touka M, Pinte S, Jenal M, Guerardel C, et al. Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1). J Biol Chem. 2009;284:20927-35 pubmed publisher
    ..Taken together, our results implicate the tumor suppressor HIC1 in the transcriptional regulation of the chemokine receptor CXCR7, a key player in the promotion of tumorigenesis in a wide variety of cell types. ..
  23. Clement K, Vaisse C, Manning B, Basdevant A, Guy Grand B, Ruiz J, et al. Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity. N Engl J Med. 1995;333:352-4 pubmed
    ..02). People with the Trp64Arg mutation of the gene for the beta 3-adrenergic receptor may have an increased capacity to gain weight. ..
  24. Guerardel C, Deltour S, Pinte S, Monte D, Begue A, Godwin A, et al. Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53. J Biol Chem. 2001;276:3078-89 pubmed
    ..Thus, HIC-1 function in the cell is controlled by a complex interplay of transcriptional and translational regulation, which could be differently affected in many human cancers. ..
  25. Baulard A, Betts J, Engohang Ndong J, Quan S, McAdam R, Brennan P, et al. Activation of the pro-drug ethionamide is regulated in mycobacteria. J Biol Chem. 2000;275:28326-31 pubmed publisher
    ..This study opens up new avenues of research relating to ETH activation in mycobacteria, possibly leading to an improved efficacy of ETH and to the generation of new anti-mycobacterial agents...
  26. Jonckheere N, Velghe A, Ducourouble M, Copin M, Renes I, Van Seuningen I. The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors. FEBS J. 2011;278:282-94 pubmed publisher
    ..The characterization of the structural and functional features of the Muc5b mucin gene will provide us with a strong base to develop studies in murine models aimed at the identification of its biological role in lung pathophysiology. ..
  27. Carnoy C, Roten C. The dif/Xer recombination systems in proteobacteria. PLoS ONE. 2009;4:e6531 pubmed publisher
    ..Our study highlights the complexity of dif/Xer recombinase systems in proteobacteria and paves the way for systematic detection of these components in prokaryotes...
  28. Gouignard N, Vanderstraete M, Cailliau K, Lescuyer A, Browaeys E, Dissous C. Schistosoma mansoni: structural and biochemical characterization of two distinct Venus Kinase Receptors. Exp Parasitol. 2012;132:32-9 pubmed publisher
    ..Recombinant SmVKR1 and SmVKR2 exhibit tyrosine kinase activities dependent on the binding of distinct small ligand molecules. SmVKR1 and SmVKR2 could represent paralogs with different functions in the parasite. ..
  29. Locht C, Geoffroy M, Renauld G. Common accessory genes for the Bordetella pertussis filamentous hemagglutinin and fimbriae share sequence similarities with the papC and papD gene families. EMBO J. 1992;11:3175-83 pubmed
    ..Deletion analyses suggest that fhaB and the downstream genes can be transcribed as a polycistronic operon, and primer extension analysis revealed the presence of a second promoter between fhaB and fhaD...
  30. Bonnefond A, Philippe J, Durand E, Dechaume A, Huyvaert M, Montagne L, et al. Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene. PLoS ONE. 2012;7:e37423 pubmed publisher
    ..e. KCNJ11, ABCC8 and INS). Therefore, the molecular diagnosis of MODY should include KCNJ11 as affected carriers can be ideally treated with oral sulfonylureas. ..
  31. Vincent M, Geneviève D, Ostertag A, Marlin S, Lacombe D, Martin Coignard D, et al. Treacher Collins syndrome: a clinical and molecular study based on a large series of patients. Genet Med. 2016;18:49-56 pubmed publisher
    ..Even though TCOF1 and POLR1D were associated with extreme clinical variability, we found no phenotype-genotype correlation. In cases with a typical phenotype of TCS, 6/146 (4%) remained with an unidentified molecular defect. ..
  32. Leiba J, Carrère Kremer S, Blondiaux N, Dimala M, Wohlkonig A, Baulard A, et al. The Mycobacterium tuberculosis transcriptional repressor EthR is negatively regulated by Serine/Threonine phosphorylation. Biochem Biophys Res Commun. 2014;446:1132-8 pubmed publisher
    ..Together, these findings are the first demonstration of EthR phosphorylation and indicate that phosphorylation negatively affects its DNA-binding activity, which may impact ETH resistance levels in M. tb. ..
  33. Porchet N, Nguyen V, Dufosse J, Audie J, Guyonnet Duperat V, Gross M, et al. Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs. Biochem Biophys Res Commun. 1991;175:414-22 pubmed
    ..This clone hybridized to polydisperse messages produced by human tracheo-bronchial and human colonic mucosae. The gene (proposed name MUC 4) from which cDNA is derived maps to chromosome 3. ..
  34. Boutin P, Dina C, Vasseur F, Dubois S, Corset L, Séron K, et al. GAD2 on chromosome 10p12 is a candidate gene for human obesity. PLoS Biol. 2003;1:E68 pubmed
    ..01, respectively). These data support the hypothesis of the orexigenic effect of GABA in humans and of a contribution of genes involved in GABA metabolism in the modulation of food intake and in the development of morbid obesity. ..
  35. Pineda Torra I, Claudel T, Duval C, Kosykh V, Fruchart J, Staels B. Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor. Mol Endocrinol. 2003;17:259-72 pubmed
    ..These results provide molecular evidence for a cross-talk between the FXR and PPARalpha pathways in humans. ..
  36. Crepieux P, Coll J, Stehelin D. The Ets family of proteins: weak modulators of gene expression in quest for transcriptional partners. Crit Rev Oncog. 1994;5:615-38 pubmed
    ..This review focuses on such interactions and also explores dysregulated expression of the Ets proteins in human cancers. ..
  37. Broly F, Marez D, Lo Guidice J, Sabbagh N, Legrand M, Boone P, et al. A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency. Hum Genet. 1995;96:601-3 pubmed
  38. Lassalle P, Molet S, Janin A, Heyden J, Tavernier J, Fiers W, et al. ESM-1 is a novel human endothelial cell-specific molecule expressed in lung and regulated by cytokines. J Biol Chem. 1996;271:20458-64 pubmed
    ..These data suggest that ESM-1 may have potent implications in the areas of vascular cell biology and human lung physiology. ..
  39. Dao Phan H, Formstecher P, Lefebvre P. Disruption of the glucocorticoid receptor assembly with heat shock protein 90 by a peptidic antiglucocorticoid. Mol Endocrinol. 1997;11:962-72 pubmed
    ..More importantly, these results demonstrate that targeting specific protein/protein interaction interfaces is a powerful means to specifically modulate nuclear receptor signaling pathways in a ligand-independent manner. ..
  40. Spruyt N, Delarbre C, Gachelin G, Laudet V. Complete sequence of the amphioxus (Branchiostoma lanceolatum) mitochondrial genome: relations to vertebrates. Nucleic Acids Res. 1998;26:3279-85 pubmed
    ..Altogether, these data clearly emphasise the close relationships between amphioxus and vertebrates, and reinforce the notion that prochordates may be viewed as the brother group of vertebrates...
  41. Delattre A, Clantin B, Saint N, Locht C, Villeret V, Jacob Dubuisson F. Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily. FEBS J. 2010;277:4755-65 pubmed publisher
  42. Laudet V, Hanni C, Coll J, Catzeflis F, Stehelin D. Evolution of the nuclear receptor gene superfamily. EMBO J. 1992;11:1003-13 pubmed
    ..These data suggest a complex evolutionary history for nuclear receptor genes in which gene duplication events and swapping between domains of different origins took place. ..
  43. Morelle W, Capon C, Balduyck M, Sautiere P, Kouach M, Michalski C, et al. Chondroitin sulphate covalently cross-links the three polypeptide chains of inter-alpha-trypsin inhibitor. Eur J Biochem. 1994;221:881-8 pubmed
  44. de Vos P, Saladin R, Auwerx J, Staels B. Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J Biol Chem. 1995;270:15958-61 pubmed
    ..Modulation of ob expression may therefore constitute a mechanism through which hormonal, pharmacological, or other factors control body weight homeostasis. ..
  45. Fréville A, Cailliau Maggio K, Pierrot C, Tellier G, Kalamou H, Lafitte S, et al. Plasmodium falciparum encodes a conserved active inhibitor-2 for Protein Phosphatase type 1: perspectives for novel anti-plasmodial therapy. BMC Biol. 2013;11:80 pubmed publisher
  46. Adelmant G, Begue A, Stehelin D, Laudet V. A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity. Proc Natl Acad Sci U S A. 1996;93:3553-8 pubmed
  47. Desseyn J, Rousseau K, Laine A. Fifty-nine bp repeat polymorphism in the uncommon intron 36 of the human mucin gene MUC5B. Electrophoresis. 1999;20:493-6 pubmed
    ..Southern blot experiments revealed the locus specificity of the repeat. The sequence of the repeat unit does not match the consensus sequence of Chi-related minisatellites. ..
  48. Ahier A, Rondard P, Gouignard N, Khayath N, Huang S, Trolet J, et al. A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacids. PLoS ONE. 2009;4:e5651 pubmed publisher
    ..The identification of RTKs specific for parasites and insect vectors raises new perspectives for the control of human parasitic and infectious diseases...
  49. Kherrouche Z, De Launoit Y, Monte D. The NRF-1/alpha-PAL transcription factor regulates human E2F6 promoter activity. Biochem J. 2004;383:529-36 pubmed
    ..Our results indicate that NRF-1/alpha-PAL is implicated in the regulation of basal E2F6 gene expression. ..
  50. Bailly C, Arafa R, Tanious F, Laine W, Tardy C, Lansiaux A, et al. Molecular determinants for DNA minor groove recognition: design of a bis-guanidinium derivative of ethidium that is highly selective for AT-rich DNA sequences. Biochemistry. 2005;44:1941-52 pubmed
    ..The chemical modulation of the ethidium exocyclic amines is a profitable option to tune the nucleic acid recognition properties of phenylphenanthridinium dyes. ..
  51. Dei Cas E, Chabé M, Moukhlis R, Durand Joly I, Aliouat E, Stringer J, et al. Pneumocystis oryctolagi sp. nov., an uncultured fungus causing pneumonia in rabbits at weaning: review of current knowledge, and description of a new taxon on genotypic, phylogenetic and phenotypic bases. FEMS Microbiol Rev. 2006;30:853-71 pubmed
    ..The present work focuses on Pneumocystis oryctolagi sp. nov. from Old-World rabbits. This new species has been described on the basis of both biological and phylogenetic species concepts. ..
  52. Ghoussaini M, Vatin V, Lecoeur C, Abkevich V, Younus A, Samson C, et al. Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity. J Clin Endocrinol Metab. 2007;92:4403-9 pubmed
    ..Our results altogether suggest that MCHR2 is not a major contributor to polygenic obesity and support a modest effect of the A76A SNP on food intake abnormalities in childhood. ..
  53. Holder Espinasse M, Martin Coignard D, Escande F, Manouvrier Hanu S. A new mutation in TP63 is associated with age-related pathology. Eur J Hum Genet. 2007;15:1115-20 pubmed
    ..The latter findings have never been reported in this condition, and could be secondary to a new TP63 deletion that has been identified in this family...
  54. Gerbod D, Edgcomb V, Noel C, Vanacova S, Wintjens R, Tachezy J, et al. Phylogenetic relationships of class II fumarase genes from trichomonad species. Mol Biol Evol. 2001;18:1574-84 pubmed
    ..Alternatively, it may have been acquired via a separate endosymbiotic event or lateral gene transfer. ..
  55. Sautiere P, Martinage A, Belaiche D, Arkhis A, Chevaillier P. Comparison of the amino acid sequences of human protamines HP2 and HP3 and of intermediate basic nuclear proteins HPS1 and HPS2. Structural evidence that HPS1 and HPS2 are pro-protamines. J Biol Chem. 1988;263:11059-62 pubmed
    ..Their amino-terminal amino acid sequences have also been determined. The structural data thus obtained suggest that HPS1 and HPS2 are precursors of human protamines HP2 and HP3. ..
  56. Bouton D, Escriva H, de Mendonça R, Glineur C, Bertin B, Noel C, et al. A conserved retinoid X receptor (RXR) from the mollusk Biomphalaria glabrata transactivates transcription in the presence of retinoids. J Mol Endocrinol. 2005;34:567-82 pubmed
    ..The nucleotide sequence reported in this paper has been submitted to the GenBank/EBI Data Bank with accession no. AY048663...
  57. Vanderstraete M, Gouignard N, Ahier A, Morel M, Vicogne J, Dissous C. The venus kinase receptor (VKR) family: structure and evolution. BMC Genomics. 2013;14:361 pubmed publisher
  58. Audie J, Tetaert D, Pigny P, Buisine M, Janin A, Aubert J, et al. Mucin gene expression in the human endocervix. Hum Reprod. 1995;10:98-102 pubmed
    ..The expression of the MUC 4 gene appears to be influenced by the oestro-progesterone ratio. During the ovulatory cycle, there are only a few differences concerning the variations of expression of all other MUC genes...
  59. Akbar H, Pinçon C, Aliouat Denis C, Derouiche S, Taylor M, Pottier M, et al. Characterizing Pneumocystis in the lungs of bats: understanding Pneumocystis evolution and the spread of Pneumocystis organisms in mammal populations. Appl Environ Microbiol. 2012;78:8122-36 pubmed publisher
    ..Moreover, the link between genetic variability of Pneumocystis isolated from populations of the same bat species and their geographic area could be exploited in terms of phylogeography. ..
  60. Duterque Coquillaud M, Niel C, Plaza S, Stehelin D. New human erg isoforms generated by alternative splicing are transcriptional activators. Oncogene. 1993;8:1865-73 pubmed
    ..The results indicated that all these erg isoforms are able to bind the ETS binding site in a specific manner. Our data using transient transfection assays indicate that erg protein isoforms function as transcriptional activators. ..
  61. Escande F, Lemaitre L, Moniaux N, Batra S, Aubert J, Buisine M. Genomic organization of MUC4 mucin gene. Towards the characterization of splice variants. Eur J Biochem. 2002;269:3637-44 pubmed
    ..Moreover, we have shown that the different MUC4 transcripts are generated by several mechanisms, including the alternative use of cassette exons, exon skipping or use of cryptic splice donor/acceptor sites. ..
  62. Oger F, Dubois F, Caby S, No l C, Cornette J, Bertin B, et al. The class I histone deacetylases of the platyhelminth parasite Schistosoma mansoni. Biochem Biophys Res Commun. 2008;377:1079-84 pubmed publisher
  63. Odaert M, Devalckenaere A, Trieu Cuot P, Simonet M. Molecular characterization of IS1541 insertions in the genome of Yersinia pestis. J Bacteriol. 1998;180:178-81 pubmed
    ..These motifs might constitute hot spots for insertion of this IS1541 element within the Y. pestis genome...
  64. Sirard J, Didierlaurent A, Cayet D, Sierro F, Rumbo M. Toll-like receptor 5- and lymphotoxin beta receptor-dependent epithelial Ccl20 expression involves the same NF-kappaB binding site but distinct NF-kappaB pathways and dynamics. Biochim Biophys Acta. 2009;1789:386-94 pubmed publisher
    ..In summary, different NF-kappaB pathways modulate CCL20 transcription by operating on the same NF-kappaB binding site in the same cell type. ..
  65. Pinte S, Guerardel C, Deltour Balerdi S, Godwin A, Leprince D. Identification of a second G-C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1. Oncogene. 2004;23:4023-31 pubmed
    ..Our results thus highlight the existence of an unexpected complex transcriptional regulation of HIC1. ..
  66. Preudhomme C, Roumier C, Hildebrand M, Dallery Prudhomme E, Lantoine D, Lai J, et al. Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myeloma. Oncogene. 2000;19:2023-32 pubmed
    ..It is the first report which describes the recurrent chromosomal alteration of a GTP-binding protein encoding gene, in patients with hematopoietic malignancies. ..
  67. Moniaux N, Escande F, Batra S, Porchet N, Laine A, Aubert J. Alternative splicing generates a family of putative secreted and membrane-associated MUC4 mucins. Eur J Biochem. 2000;267:4536-44 pubmed
    ..Although no specific function has yet been discovered for the family of proteins putatively produced from the unique MUC4 gene, we suspect that the MUC4 proteins may be implicated in the integrity and renewal of the epithelium. ..
  68. Lynch P, Krivosic Horber R, Reyford H, Monnier N, Quane K, Adnet P, et al. Identification of heterozygous and homozygous individuals with the novel RYR1 mutation Cys35Arg in a large kindred. Anesthesiology. 1997;86:620-6 pubmed
    ..The sensitivity of muscle samples to caffeine clearly distinguished the two homozygotes from other heterozygous-susceptible individuals. No clear differentiation was observed with the halothane contracture results. ..
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