Experts and Doctors on membrane transport proteins in Paris, Île de France, France

Summary

Locale: Paris, Île de France, France
Topic: membrane transport proteins

Top Publications

  1. Vanet A, Plumbridge J, Alix J. Cotranscription of two genes necessary for ribosomal protein L11 methylation (prmA) and pantothenate transport (panF) in Escherichia coli K-12. J Bacteriol. 1993;175:7178-88 pubmed
    ..Although no promoter activity was detected immediately upstream of prmA, S1 mapping detected 5' ends of mRNA in this region, implying that some mRNA processing occurs within the bicistronic panF-prmA mRNA. ..
  2. Dupre S, Haguenauer Tsapis R. Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase. Mol Cell Biol. 2001;21:4482-94 pubmed
    ..Doa4p thus appears to be involved in the deubiquitination of endocytosed plasma membrane proteins, some of them carrying UbK63 linkages. ..
  3. Reis A, Dubois Laforgue D, Bellanne Chantelot C, Timsit J, Velho G. A polymorphism in the promoter of UCP2 gene modulates lipid levels in patients with type 2 diabetes. Mol Genet Metab. 2004;82:339-44 pubmed
    ..The implications of this effect in the evolution of type 2 diabetes and its macrovascular complications deserve to be investigated. ..
  4. Enninga J, Rosenshine I. Imaging the assembly, structure and activity of type III secretion systems. Cell Microbiol. 2009;11:1462-70 pubmed publisher
    ..Furthermore, we highlight recent imaging innovations with the potential to provide better insight into the T3SS structure and function. ..
  5. Bankir L, Yang B. New insights into urea and glucose handling by the kidney, and the urine concentrating mechanism. Kidney Int. 2012;81:1179-98 pubmed publisher
    ..These hypotheses are all based on published findings. They may not all be confirmed later on, but we hope they will stimulate further research in new directions. ..
  6. Picciotto M, Zoli M, Rimondini R, Lena C, Marubio L, Pich E, et al. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature. 1998;391:173-7 pubmed
    ..Our results strongly support the idea that the beta2-containing neuronal nicotinic acetylcholine receptor is involved in mediating the reinforcing properties of nicotine. ..
  7. van Endert P. Genes regulating MHC class I processing of antigen. Curr Opin Immunol. 1999;11:82-8 pubmed
    ..Finally, genetic evidence suggests an important influence of an unidentified gene, in the MHC complex, on MHC class I processing...
  8. Sidoux Walter F, Lucien N, Olives B, Gobin R, Rousselet G, Kamsteeg E, et al. At physiological expression levels the Kidd blood group/urea transporter protein is not a water channel. J Biol Chem. 1999;274:30228-35 pubmed
  9. Blons H, Feldmann D, Duval V, Messaz O, Denoyelle F, Loundon N, et al. Screening of SLC26A4 (PDS) gene in Pendred's syndrome: a large spectrum of mutations in France and phenotypic heterogeneity. Clin Genet. 2004;66:333-40 pubmed
    ..The main clinical characteristics were: early hearing loss, fluctuation in terms of during deafness evolution, and the presence of an enlarged vestibular aqueduct...

More Information

Publications104 found, 100 shown here

  1. Nubel T, Ricquier D. Respiration under control of uncoupling proteins: Clinical perspective. Horm Res. 2006;65:300-10 pubmed
    ..This lively awaited information may be the basis for potential pharmacological targeting of the UCPs in future. ..
  2. Sancho Shimizu V, Zhang S, Abel L, Tardieu M, Rozenberg F, Jouanguy E, et al. Genetic susceptibility to herpes simplex virus 1 encephalitis in mice and humans. Curr Opin Allergy Clin Immunol. 2007;7:495-505 pubmed
    ..This is not only crucial for the understanding of immunity to herpes simplex virus 1, but also for the diagnosis and treatment of herpes simplex encephalitis. ..
  3. Rolland A, Tande D, Herrero M, Luquin M, Vazquez Claverie M, Karachi C, et al. Evidence for a dopaminergic innervation of the pedunculopontine nucleus in monkeys, and its drastic reduction after MPTP intoxication. J Neurochem. 2009;110:1321-9 pubmed publisher
  4. Cheval L, Pierrat F, Dossat C, Genete M, Imbert Teboul M, Duong Van Huyen J, et al. Atlas of gene expression in the mouse kidney: new features of glomerular parietal cells. Physiol Genomics. 2011;43:161-73 pubmed publisher
    ..Finally, functional annotation of glomerulus-specific transcripts suggested a high proliferation activity of glomerular cells. Immunolabeling for PCNA confirmed a high percentage of proliferating cells in the glomerulus parietal sheet. ..
  5. André P, Saubamea B, Cochois Guégan V, Marie Claire C, Cattelotte J, Smirnova M, et al. Transport of biogenic amine neurotransmitters at the mouse blood-retina and blood-brain barriers by uptake1 and uptake2. J Cereb Blood Flow Metab. 2012;32:1989-2001 pubmed publisher
    ..These heterogeneous transport properties of the brain and retina NVUs suggest that the BBB helps protect the brain against biogenic amine neurotransmitters in the plasma while the BRB has more of a metabolic/endocrine role. ..
  6. Beaufort N, Corvazier E, Mlanaoindrou S, de Bentzmann S, Pidard D. Disruption of the endothelial barrier by proteases from the bacterial pathogen Pseudomonas aeruginosa: implication of matrilysis and receptor cleavage. PLoS ONE. 2013;8:e75708 pubmed publisher
  7. Rigaud J, Mosser G, Lacapere J, Olofsson A, Levy D, Ranck J. Bio-Beads: an efficient strategy for two-dimensional crystallization of membrane proteins. J Struct Biol. 1997;118:226-35 pubmed
    ..Different crystals could be produced from all protein preparations, with optical diffraction down to 20-25 A in negative stain. ..
  8. Jouanguy E, Zhang S, Chapgier A, Sancho Shimizu V, Puel A, Picard C, et al. Human primary immunodeficiencies of type I interferons. Biochimie. 2007;89:878-83 pubmed
    ..These novel inherited disorders strongly suggest that type I IFN-mediated immunity is essential for protection against natural infections caused by several viruses in humans. ..
  9. Molinari F, Kaminska A, Fiermonte G, Boddaert N, Raas Rothschild A, Plouin P, et al. Mutations in the mitochondrial glutamate carrier SLC25A22 in neonatal epileptic encephalopathy with suppression bursts. Clin Genet. 2009;76:188-94 pubmed publisher
    ..Comparison of the clinical features of patients from both families suggests that SLC25A22 mutations are responsible for a novel clinically recognizable epileptic encephalopathy with SB. ..
  10. Mazuet C, Yoon E, Boyer S, Pignier S, Blanc T, Doehring I, et al. A penicillin- and metronidazole-resistant Clostridium botulinum strain responsible for an infant botulism case. Clin Microbiol Infect. 2016;22:644.e7-644.e12 pubmed publisher
    ..botulinum. This is the first report of a C. botulinum isolate resistant to penicillins. This stresses the importance of antibiotic susceptibility testing for adequate therapy of botulism. ..
  11. Bakouh N, Bellanca S, Nyboer B, Moliner Cubel S, Karim Z, Sanchez C, et al. Iron is a substrate of the Plasmodium falciparum chloroquine resistance transporter PfCRT in Xenopus oocytes. J Biol Chem. 2017;292:16109-16121 pubmed publisher
    ..If these findings in the Xenopus model extend to P. falciparum in vivo, our data suggest that PfCRT might play a role in iron homeostasis, which is essential for the parasite's development in erythrocytes. ..
  12. Fabre V, Beaufour C, Evrard A, Rioux A, Hanoun N, Lesch K, et al. Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter. Eur J Neurosci. 2000;12:2299-310 pubmed
    ..Such effects were not detected in 5-HTT-/- mice, further confirming the occurrence of marked alterations of 5-HT1A and 5-HT1B autoreceptors in these animals. ..
  13. Herve D, Le Moine C, Corvol J, Belluscio L, Ledent C, Fienberg A, et al. Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum. J Neurosci. 2001;21:4390-9 pubmed
    ..Together, these results identify Galpha(olf) as a critical and regulated component of both dopamine and adenosine signaling. ..
  14. Rebsam A, Seif I, Gaspar P. Refinement of thalamocortical arbors and emergence of barrel domains in the primary somatosensory cortex: a study of normal and monoamine oxidase a knock-out mice. J Neurosci. 2002;22:8541-52 pubmed
    ..Our results indicate that the barrel-deficient phenotype of MAOA-KO mice results from an altered refinement of the TCA arbors in their target layer IV, involving branch elaboration and collateral retraction during early postnatal life. ..
  15. Kalatzis V, Cohen Solal L, Cordier B, Frishberg Y, Kemper M, Nuutinen E, et al. Identification of 14 novel CTNS mutations and characterization of seven splice site mutations associated with cystinosis. Hum Mutat. 2002;20:439-46 pubmed
    ..8%. Interestingly, the few undetectable mono- or bi-allelic mutations segregated mostly in the noninfantile forms, suggesting that these individuals carry mutations either in the introns or in unidentified regulatory sequences. ..
  16. Legros F, Lombes A, Frachon P, Rojo M. Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol Biol Cell. 2002;13:4343-54 pubmed
    ..These results show that human mitochondria represent a single cellular compartment whose exchanges and interconnectivity are dynamically regulated by the balance between continuous fusion and fission reactions. ..
  17. Froger N, Jammoul F, Gaucher D, Cadetti L, Lorach H, Dégardin J, et al. Taurine is a crucial factor to preserve retinal ganglion cell survival. Adv Exp Med Biol. 2013;775:69-83 pubmed publisher
    ..These data suggest that the retinal taurine level is a crucial marker to prevent RGC damage in major retinal diseases. ..
  18. Gómez Zepeda D, Chaves C, Taghi M, Sergent P, Liu W, Chhuon C, et al. Targeted unlabeled multiple reaction monitoring analysis of cell markers for the study of sample heterogeneity in isolated rat brain cortical microvessels. J Neurochem. 2017;142:597-609 pubmed publisher
    ..89) and moderate to high with Bcrp (r ? 0.77), that can be found also in pericytes and astrocytes. Therefore, Pecam-1 was selected as a marker for the normalization of the quantification of the proteins of endothelial cells. ..
  19. Martres M, Demeneix B, Hanoun N, Hamon M, Giros B. Up- and down-expression of the dopamine transporter by plasmid DNA transfer in the rat brain. Eur J Neurosci. 1998;10:3607-16 pubmed
    ..These data indicate that non-viral transfer of the sense or antisense coding sequence of DAT can be used as a novel approach to induce long-term changes in central DA neurotransmission. ..
  20. Gasnier B, Scherman D, Henry J. Inactivation of the catecholamine transporter during the preparation of chromaffin granule membrane 'ghosts'. FEBS Lett. 1987;222:215-9 pubmed
    ..The reserpine to dihydrotetrabenazine binding ratio (10-25%) is an estimate of the proportion of correctly resealed vesicles. ..
  21. Chauleau M, Mora L, Serba J, de Zamaroczy M. FtsH-dependent processing of RNase colicins D and E3 means that only the cytotoxic domains are imported into the cytoplasm. J Biol Chem. 2011;286:29397-407 pubmed publisher
    ..Even though the OmpT-catalyzed in vitro cleavage also liberates the catalytic domain from colicins D and E3, it is not involved in the processing of nuclease colicins during their import into the cytoplasm. ..
  22. Olives B, Martial S, Mattei M, Matassi G, Rousselet G, Ripoche P, et al. Molecular characterization of a new urea transporter in the human kidney. FEBS Lett. 1996;386:156-60 pubmed
    ..By in situ hybridization, the gene encoding HUT2 has been assigned to chromosome 18q12.1-q21-1, as found previously for the Kidd/urea transporter HUT11, suggesting that both genes evolved from duplication of a common ancestor. ..
  23. Upton A, Ravary A, Salichon N, Moessner R, Lesch K, Hen R, et al. Lack of 5-HT(1B) receptor and of serotonin transporter have different effects on the segregation of retinal axons in the lateral geniculate nucleus compared to the superior colliculus. Neuroscience. 2002;111:597-610 pubmed
  24. Fribourg P, Chami M, Sorzano C, Gubellini F, Marabini R, Marco S, et al. 3D cryo-electron reconstruction of BmrA, a bacterial multidrug ABC transporter in an inward-facing conformation and in a lipidic environment. J Mol Biol. 2014;426:2059-69 pubmed publisher
    ..Overall, the data are consistent with a mechanism of drug transport involving large conformational changes of BmrA and show that a bacterial ABC exporter can adopt at least two open inward conformations in lipid membrane...
  25. Krejci E, Gasnier B, Botton D, Isambert M, Sagne C, Gagnon J, et al. Expression and regulation of the bovine vesicular monoamine transporter gene. FEBS Lett. 1993;335:27-32 pubmed
  26. Kalatzis V, Cherqui S, Antignac C, Gasnier B. Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter. EMBO J. 2001;20:5940-9 pubmed
  27. Aubert Pivert E, Davies J. Biosynthesis of butirosin in Bacillus circulans NRRL B3312: identification by sequence analysis and insertional mutagenesis of the butB gene involved in antibiotic production. Gene. 1994;147:1-11 pubmed
    ..It is proposed that ButB plays a role in the export of But from the producing organism. ..
  28. Cartron J, Ripoche P. Urea transport and Kidd blood groups. Transfus Clin Biol. 1995;2:309-15 pubmed
    ..All these findings provide evidence that the Kidd locus encodes for the human erythrocyte urea transporter, offering new prospects for biological study of urea transporters and their tissue-specific regulation. ..
  29. Boyer J, Michaux G, Fairhead C, Gaillon L, Dujon B. Sequence and analysis of a 26.9 kb fragment from chromosome XV of the yeast Saccharomyces cerevisiae. Yeast. 1996;12:1575-86 pubmed
    ..The present sequence corresponds to coordinates 772,331 to 799,187 of the entire chromosome XV sequence which can be retrieved by anonymous ftp (ftp. mips. embnet. org). ..
  30. Callebaut I, Mornon J. The human EBNA-2 coactivator p100: multidomain organization and relationship to the staphylococcal nuclease fold and to the tudor protein involved in Drosophila melanogaster development. Biochem J. 1997;321 ( Pt 1):125-32 pubmed
    ..We named this heretofore undescribed domain the 'tudor domain' and highlight within it five invariant residues which could be involved in one of the essential roles played by these proteins. ..
  31. Lucien N, Sidoux Walter F, Olives B, Moulds J, Le Pennec P, Cartron J, et al. Characterization of the gene encoding the human Kidd blood group/urea transporter protein. Evidence for splice site mutations in Jknull individuals. J Biol Chem. 1998;273:12973-80 pubmed
    ..These findings provide a rational explanation for the lack of Kidd/urea transporter protein and defect in urea transport of Jknull cells. ..
  32. Masson J, Sagne C, Hamon M, El Mestikawy S. Neurotransmitter transporters in the central nervous system. Pharmacol Rev. 1999;51:439-64 pubmed
  33. Ferrandez Y, Monlezun L, Phan G, Benabdelhak H, Benas P, Ulryck N, et al. Stoichiometry of the MexA-OprM binding, as investigated by blue native gel electrophoresis. Electrophoresis. 2012;33:1282-7 pubmed publisher
    ..Then we proved that MexA has to be palmitylated in order to stabilized the complex formation with OprM. Finally, we provided evidence for a two by two (2, 4, 6, or upper) binding of palmitylated MexA per trimer of OprM. ..
  34. Binet R, Wandersman C. Cloning of the Serratia marcescens hasF gene encoding the Has ABC exporter outer membrane component: a TolC analogue. Mol Microbiol. 1996;22:265-73 pubmed
    ..This suggests that the various functions of TolC could correspond to distinct domains on the protein...
  35. Galan J, Haguenauer Tsapis R. Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein. EMBO J. 1997;16:5847-54 pubmed
    ..We have thus identified a natural target of Lys63-linked ubiquitin chains. We have also shown that monoubiquitination is sufficient to induce permease endocytosis, but that Lys63-linked ubiquitin chains appear to stimulate this process. ..
  36. Millan M, Gobert A, Lejeune F, Newman Tancredi A, Rivet J, Auclair A, et al. S33005, a novel ligand at both serotonin and norepinephrine transporters: I. Receptor binding, electrophysiological, and neurochemical profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine. J Pharmacol Exp Ther. 2001;298:565-80 pubmed
    ..It enhances extracellular levels of 5-HT and NE throughout corticolimbic structures and selectively elevates dialysis levels of DA in frontal cortex versus subcortical regions...
  37. Koszul R, Malpertuy A, Frangeul L, Bouchier C, Wincker P, Thierry A, et al. The complete mitochondrial genome sequence of the pathogenic yeast Candida (Torulopsis) glabrata. FEBS Lett. 2003;534:39-48 pubmed
    ..Three group I introns each with an intronic open reading frame are present in the COX1 gene. This sequence is available under accession number AJ511533...
  38. Chambrey R, Goossens D, Bourgeois S, Picard N, Bloch Faure M, Leviel F, et al. Genetic ablation of Rhbg in the mouse does not impair renal ammonium excretion. Am J Physiol Renal Physiol. 2005;289:F1281-90 pubmed
    ..We conclude that Rhbg is not a critical determinant of NH(4)(+) excretion by the kidney and of NH(4)(+) detoxification by the liver in vivo. ..
  39. Hurtaud C, Gelly C, Bouillaud F, Levi Meyrueis C. Translation control of UCP2 synthesis by the upstream open reading frame. Cell Mol Life Sci. 2006;63:1780-9 pubmed
    ..We discuss our results within the framework of the existing models explaining initiation of translation downstream of a uORF. ..
  40. Izzedine H, Hulot J, Villard E, Goyenvalle C, Dominguez S, Ghosn J, et al. Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy. J Infect Dis. 2006;194:1481-91 pubmed
    ..2% of the group 2 control subjects (P<.01). No association was observed between ABCC4 polymorphism and TDF-induced rPT in the present study. ABCC2 haplotypes are associated with rPT induced by TDF in HIV-1-infected patients. ..
  41. Soares R, Do T, Mabondzo A, Pons G, Chhun S. Ontogeny of ABC and SLC transporters in the microvessels of developing rat brain. Fundam Clin Pharmacol. 2016;30:107-16 pubmed publisher
    ..Accordingly to our results, we suppose that age may be another factor influencing brain exposure to antiepileptics as a consequence of different expression patterns of efflux transporters between the adult and immature BBB. ..
  42. Lebrand C, Cases O, Wehrle R, Blakely R, Edwards R, Gaspar P. Transient developmental expression of monoamine transporters in the rodent forebrain. J Comp Neurol. 1998;401:506-24 pubmed
    ..These expressions did not seem to be dependent on peripheral neural inputs, since monocular enucleations and infraorbital nerve cuts effected on the day of birth, did not modify the period of transporter expression or of extinction. ..
  43. Cherqui S, Kalatzis V, Trugnan G, Antignac C. The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif. J Biol Chem. 2001;276:13314-21 pubmed
    ..Using site-directed mutagenesis studies we identified a novel conformational lysosomal-sorting motif, the core of which was delineated to YFPQA (amino acids 281-285)...
  44. Fontayne A, Dang P, Gougerot Pocidalo M, El Benna J. Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation. Biochemistry. 2002;41:7743-50 pubmed
    ..In addition, phosphorylation of some serines could have an inhibitory effect on oxidase activation. ..
  45. Cherqui S, Sevin C, Hamard G, Kalatzis V, Sich M, Pequignot M, et al. Intralysosomal cystine accumulation in mice lacking cystinosin, the protein defective in cystinosis. Mol Cell Biol. 2002;22:7622-32 pubmed
    ..This animal model will prove an invaluable and unique tool for testing emerging therapeutics for cystinosis. ..
  46. Bayle F, Leroy S, Gourion D, Millet B, Olie J, Poirier M, et al. 5HTTLPR polymorphism in schizophrenic patients: further support for association with violent suicide attempts. Am J Med Genet B Neuropsychiatr Genet. 2003;119B:13-7 pubmed
    ..Although replication studies are warranted, these results in schizophrenia further support the hypothesis that 5HTTLPR polymorphism is a risk factor for violent suicidal behavior. ..
  47. Le Fur S, Le Stunff C, Dos Santos C, Bougneres P. The common -866 G/A polymorphism in the promoter of uncoupling protein 2 is associated with increased carbohydrate and decreased lipid oxidation in juvenile obesity. Diabetes. 2004;53:235-9 pubmed
    ..6 +/- 1.2) of calories derived from carbohydrates to those from lipids compared with G/A or G/G obese children (1.4 +/- 0.2, P = 0.003), suggesting a role for UCP2 in the partitioning of metabolic fuels. ..
  48. Zidi Yahiaoui N, Mouro Chanteloup I, D Ambrosio A, Lopez C, Gane P, Le Van Kim C, et al. Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells. Biochem J. 2005;391:33-40 pubmed
    ..Natl. Acad. Sci. U.S.A. 101, 17222-17227] constitute a family of NH3 channels in mammalian cells...
  49. Lucotte G, Mercier G, Dieterlen F, Yuasa I. A decreasing gradient of 374F allele frequencies in the skin pigmentation gene SLC45A2, from the north of West Europe to North Africa. Biochem Genet. 2010;48:26-33 pubmed publisher
    ..869). The results confirm that the distribution of the 374F allele may reflect the ultraviolet radiation level and can be associated with skin color variation in these regions. ..
  50. Martinez Jéhanne V, Pichon C, du Merle L, Poupel O, Cayet N, Bouchier C, et al. Role of the vpe carbohydrate permease in Escherichia coli urovirulence and fitness in vivo. Infect Immun. 2012;80:2655-66 pubmed publisher
    ..These findings confirm that carbohydrate transport and metabolism underlie the ability of UPEC strains to colonize the host intestine and to infect various host sites. ..
  51. Biville F, Turlin E, Gasser F. Mutants of Escherichia coli producing pyrroloquinoline quinone. J Gen Microbiol. 1991;137:1775-82 pubmed
    ..Glucose utilization by EF mutants was strictly aerobic as expected from a PQQ-dependent catabolism. The regulation of PQQ production by E. coli is discussed. ..
  52. Olives B, Neau P, Bailly P, Hediger M, Rousselet G, Cartron J, et al. Cloning and functional expression of a urea transporter from human bone marrow cells. J Biol Chem. 1994;269:31649-52 pubmed
    ..These findings suggest that HUT11 is most likely responsible for the facilitated urea transport in human red blood cells. ..
  53. Adelbrecht C, Agid Y, Raisman Vozari R. Effect of the weaver mutation on the expression of dopamine membrane transporter, tyrosine hydroxylase and vesicular monoamine transporter in dopaminergic neurons of the substantia nigra and the ventral tegmental area. Brain Res Mol Brain Res. 1996;43:291-300 pubmed
    ..The alteration of the DA membrane transporter could play a role in the progression of DA neuronal death in the wv mice. ..
  54. Sagne C, El Mestikawy S, Isambert M, Hamon M, Henry J, Giros B, et al. Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases. FEBS Lett. 1997;417:177-83 pubmed
    ..These observations, consistent with previous data on GABA and glycine uptake by synaptic vesicles, demonstrate that the mouse clone encodes a vesicular inhibitory amino acid transporter. ..
  55. Strobel A, Combettes Souverain M, Doare L, Strosberg A, Issad T. Rat uncoupling protein 2 (UCP2): expression in obese ventromedial hypothalamus (VMH)-lesioned animals. Int J Obes Relat Metab Disord. 1998;22:1121-6 pubmed
  56. Rioux A, Fabre V, Lesch K, Moessner R, Murphy D, Lanfumey L, et al. Adaptive changes of serotonin 5-HT2A receptors in mice lacking the serotonin transporter. Neurosci Lett. 1999;262:113-6 pubmed
  57. Quentin F, Eladari D, Cheval L, Lopez C, Goossens D, Colin Y, et al. RhBG and RhCG, the putative ammonia transporters, are expressed in the same cells in the distal nephron. J Am Soc Nephrol. 2003;14:545-54 pubmed
    ..In conclusion, RhBG and RhCG are present in a major site of ammonia secretion in the kidney, i.e., the CNT and CD, in agreement with their putative role in ammonium transport. ..
  58. Rumajogee P, Vergé D, Hanoun N, Brisorgueil M, Hen R, Lesch K, et al. Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP. Eur J Neurosci. 2004;19:937-44 pubmed
  59. Taillé C, El Benna J, Lanone S, Dang M, Ogier Denis E, Aubier M, et al. Induction of heme oxygenase-1 inhibits NAD(P)H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability. J Biol Chem. 2004;279:28681-8 pubmed
    ..This study provides a new mechanism to explain HO-1 anti-oxidant properties. ..
  60. Albert S, Blons H, Jonard L, Feldmann D, Chauvin P, Loundon N, et al. SLC26A4 gene is frequently involved in nonsyndromic hearing impairment with enlarged vestibular aqueduct in Caucasian populations. Eur J Hum Genet. 2006;14:773-9 pubmed
    ..SLC26A4 could be the second most frequent gene implicated in nonsyndromic deafness after GJB2, in this Caucasian population...
  61. Lepagnol Bestel A, Maussion G, Boda B, Cardona A, Iwayama Y, Delezoide A, et al. SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects. Mol Psychiatry. 2008;13:385-97 pubmed publisher
  62. Grailhe R, Cardona A, Even N, Seif I, Changeux J, Cloëz Tayarani I. Regional changes in the cholinergic system in mice lacking monoamine oxidase A. Brain Res Bull. 2009;78:283-9 pubmed publisher
    ..Our data suggest that genetic deficiency in MAOA enzyme is associated with changes in cholinergic activity, which may account for some of the behavioral alterations observed in mice and humans lacking MAOA. ..
  63. Jonard L, Niasme Grare M, Bonnet C, Feldmann D, Rouillon I, Loundon N, et al. Screening of SLC26A4, FOXI1 and KCNJ10 genes in unilateral hearing impairment with ipsilateral enlarged vestibular aqueduct. Int J Pediatr Otorhinolaryngol. 2010;74:1049-53 pubmed publisher
    ..To investigate the implication of SLC26A4, FOXI and KCNJ10 genes in unilateral hearing impairment associated with ipsilateral inner ear malformation (Enlargement of the vestibular aqueduct and/or Mondini dysplasia)...
  64. Kelly Aubert M, Trudel S, Fritsch J, Nguyen Khoa T, Baudouin Legros M, Moriceau S, et al. GSH monoethyl ester rescues mitochondrial defects in cystic fibrosis models. Hum Mol Genet. 2011;20:2745-59 pubmed publisher
    ..These studies provide evidence for a critical role of a mtGSH defect in mitochondrial dysfunction and abnormal IL-8 secretion in CF cells and reveal the therapeutic potential of mitochondria-targeted antioxidants in CF. ..
  65. Yoon E, Chabane Y, Goussard S, Snesrud E, Courvalin P, Dé E, et al. Contribution of resistance-nodulation-cell division efflux systems to antibiotic resistance and biofilm formation in Acinetobacter baumannii. MBio. 2015;6: pubmed publisher
  66. Scherman D, Gasnier B, Jaudon P, Henry J. Hydrophobicity of the tetrabenazine-binding site of the chromaffin granule monoamine transporter. Mol Pharmacol. 1988;33:72-7 pubmed
    ..Reserpine, haloperidol, and chlorpromazine have much lower intrinsic affinity for the TBZ-binding site. ..
  67. Henry J, Sagne C, Bedet C, Gasnier B. The vesicular monoamine transporter: from chromaffin granule to brain. Neurochem Int. 1998;32:227-46 pubmed
    ..The possibility of regulations at the vesicular transporter level and of their effect on the quantum size has to be investigated. The vesicular monoamine transporter is also an important target for brain imaging. ..
  68. Plumbridge J, Vimr E. Convergent pathways for utilization of the amino sugars N-acetylglucosamine, N-acetylmannosamine, and N-acetylneuraminic acid by Escherichia coli. J Bacteriol. 1999;181:47-54 pubmed
    ..The existence of a ManNAc kinase and epimerase within the nan operon allows us to propose that the pathways for dissimilation of the three amino sugars GlcNAc, ManNAc, and NANA, all converge at the step of GlcNAc-6-P. ..
  69. Llorente B, Dujon B. Transcriptional regulation of the Saccharomyces cerevisiae DAL5 gene family and identification of the high affinity nicotinic acid permease TNA1 (YGR260w). FEBS Lett. 2000;475:237-41 pubmed
    ..Its apparent K(m) of 1.7 microM is low enough to allow the uptake of the low concentrations of nicotinic acid normally secreted by wild type cells. ..
  70. Millan M, Dekeyne A, Papp M, La Rochelle C, MacSweeny C, Peglion J, et al. S33005, a novel ligand at both serotonin and norepinephrine transporters: II. Behavioral profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine. J Pharmacol Exp Ther. 2001;298:581-91 pubmed
    ..It exerts its actions more potently than venlafaxine and clomipramine, and its overall profile is distinct from those of citalopram and reboxetine...
  71. Fumeron F, Betoulle D, Nicaud V, Evans A, Kee F, Ruidavets J, et al. Serotonin transporter gene polymorphism and myocardial infarction: Etude Cas-Témoins de l'Infarctus du Myocarde (ECTIM). Circulation. 2002;105:2943-5 pubmed
    ..This could be attributable to the effect of the polymorphism on serotonin-mediated platelet activation or smooth muscle cell proliferation or on other risk factors, such as depression or response to stress. ..
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