Experts and Doctors on bacterial proteins in Paris, Île de France, France

Summary

Locale: Paris, Île de France, France
Topic: bacterial proteins

Top Publications

  1. Munier H, Gilles A, Glaser P, Krin E, Danchin A, Sarfati R, et al. Isolation and characterization of catalytic and calmodulin-binding domains of Bordetella pertussis adenylate cyclase. Eur J Biochem. 1991;196:469-74 pubmed
    ..Reassociation was enhanced by calmodulin itself, which 'trapped' the two complementary peptides into a stable, native-like, ternary complex, which shows similar catalytic properties to intact adenylate cyclase...
  2. Berthet F, Rauzier J, Lim E, Philipp W, Gicquel B, Portnoi D. Characterization of the Mycobacterium tuberculosis erp gene encoding a potential cell surface protein with repetitive structures. Microbiology. 1995;141 ( Pt 9):2123-30 pubmed
    ..leprae, erp sequences were found in other members of the M. tuberculosis complex, but not in other mycobacteria tested. These results suggest that erp might encode a cell surface component shared by major pathogenic mycobacteria. ..
  3. Plumbridge J, Kolb A. DNA loop formation between Nag repressor molecules bound to its two operator sites is necessary for repression of the nag regulon of Escherichia coli in vivo. Mol Microbiol. 1993;10:973-81 pubmed
    ..These observations show that repression is the result of co-operative binding of the repressor to its two sites, resulting in the formation of a loop of DNA. ..
  4. Old I, Margarita D, Saint Girons I. Unique genetic arrangement in the dnaA region of the Borrelia burgdorferi linear chromosome: nucleotide sequence of the dnaA gene. FEMS Microbiol Lett. 1993;111:109-14 pubmed
    ..In addition B. burgdorferi DnaA protein differs considerably from those of other eubacteria in a normally highly conserved region at the C-terminus of the polypeptide which may be involved in DNA binding. ..
  5. Arthur M, Reynolds P, Courvalin P. Glycopeptide resistance in enterococci. Trends Microbiol. 1996;4:401-7 pubmed
  6. Franza T, Sauvage C, Expert D. Iron regulation and pathogenicity in Erwinia chrysanthemi 3937: role of the Fur repressor protein. Mol Plant Microbe Interact. 1999;12:119-28 pubmed
    ..These findings indicate that, in E. chrysanthemi 3937, (i) Fur negatively controls iron transport and genes encoding PelD and PelE, and (ii) additional factor(s) mediate iron regulation of the pel genes. ..
  7. Izadi Pruneyre N, Wolff N, Redeker V, Wandersman C, Delepierre M, Lecroisey A. NMR studies of the C-terminal secretion signal of the haem-binding protein, HasA. Eur J Biochem. 1999;261:562-8 pubmed
    ..This flexibility may be a prerequisite to the recognition of HasA by its ABC transporter. We determine the cleavage site of the C-terminal extremity of the protein and analyse the effect of the cleavage on the haem acquisition process...
  8. Francetic O, Badaut C, Rimsky S, Pugsley A. The ChiA (YheB) protein of Escherichia coli K-12 is an endochitinase whose gene is negatively controlled by the nucleoid-structuring protein H-NS. Mol Microbiol. 2000;35:1506-17 pubmed
    ..A possible physiological function of ChiA (YheB) endochitinase in E. coli K-12 is discussed. ..
  9. Balandina A, Kamashev D, Rouviere Yaniv J. The bacterial histone-like protein HU specifically recognizes similar structures in all nucleic acids. DNA, RNA, and their hybrids. J Biol Chem. 2002;277:27622-8 pubmed

More Information

Publications280 found, 100 shown here

  1. Depardieu F, Bonora M, Reynolds P, Courvalin P. The vanG glycopeptide resistance operon from Enterococcus faecalis revisited. Mol Microbiol. 2003;50:931-48 pubmed
    ..Sequence determination of the flanking regions of the vanG cluster in donor and transconjugants revealed the same 4 bp direct repeats and 22 bp imperfect inverted repeats that delineated the large element. ..
  2. Arluison V, Folichon M, Marco S, Derreumaux P, Pellegrini O, Seguin J, et al. The C-terminal domain of Escherichia coli Hfq increases the stability of the hexamer. Eur J Biochem. 2004;271:1258-65 pubmed
    ..On the basis of these results, we propose that the C-terminal domain could protect the interface between the subunits and stabilize the hexameric Hfq structure. The origin of this C-terminal domain is also discussed. ..
  3. Cazalet C, Gomez Valero L, Rusniok C, Lomma M, Dervins Ravault D, Newton H, et al. Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease. PLoS Genet. 2010;6:e1000851 pubmed publisher
    ..longbeachae is encapsulated. These species-specific differences may account for the different environmental niches and disease epidemiology of these two Legionella species...
  4. Pennini M, Perrinet S, Dautry Varsat A, Subtil A. Histone methylation by NUE, a novel nuclear effector of the intracellular pathogen Chlamydia trachomatis. PLoS Pathog. 2010;6:e1000995 pubmed publisher
    ..Thus, NUE is secreted by Chlamydia, translocates to the host cell nucleus and has enzymatic activity towards eukaryotic substrates. This work is the first description of a bacterial effector that directly targets mammalian histones. ..
  5. André G, Haudecoeur E, Monot M, Ohtani K, Shimizu T, Dupuy B, et al. Global regulation of gene expression in response to cysteine availability in Clostridium perfringens. BMC Microbiol. 2010;10:234 pubmed publisher
    ..The existence of links between the C. perfringens virulence regulon and sulfur metabolism prompted us to analyze this metabolism in more detail...
  6. Poirel L, Al Maskari Z, Al Rashdi F, Bernabeu S, Nordmann P. NDM-1-producing Klebsiella pneumoniae isolated in the Sultanate of Oman. J Antimicrob Chemother. 2011;66:304-6 pubmed publisher
    ..In both isolates, the bla(NDM-1) gene was located on plasmids that were of similar size (170 kb), but of different incompatibility groups. This is the first description of NDM-1 producers in the Arabian peninsula and in the Middle East. ..
  7. Rolando M, Buchrieser C. Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy. Future Microbiol. 2012;7:369-81 pubmed publisher
    ..In this review, we focus on those effectors in the repertoire of L. pneumophila proteins that target key cellular pathways by specific post-translational modifications...
  8. Caillet Saguy C, Piccioli M, Turano P, Lukat Rodgers G, Wolff N, Rodgers K, et al. Role of the iron axial ligands of heme carrier HasA in heme uptake and release. J Biol Chem. 2012;287:26932-43 pubmed publisher
    ..Here, we demonstrate that these states do not naturally occur in the free protein but can only be driven by the interaction with the partner proteins. ..
  9. Durand S, Jahn N, Condon C, Brantl S. Type I toxin-antitoxin systems in Bacillus subtilis. RNA Biol. 2012;9:1491-7 pubmed publisher
    ..Here we review what is known about these confirmed and putative toxin-antitoxin families in B. subtilis, their regulatory mechanisms, their potential roles and how they may link to the physiology of the cell. ..
  10. Turlin E, Debarbouille M, Augustyniak K, Gilles A, Wandersman C. Staphylococcus aureus FepA and FepB proteins drive heme iron utilization in Escherichia coli. PLoS ONE. 2013;8:e56529 pubmed publisher
    ..Our results show that the function in heme iron extraction is conserved in the two orthologous systems. ..
  11. Plumbridge J. A dominant mutation in the gene for the Nag repressor of Escherichia coli that renders the nag regulon uninducible. J Gen Microbiol. 1992;138:1011-7 pubmed
    ..The mutation is semi-dominant since heterozygous diploids have reduced growth rates on glucosamine and N-acetylglucosamine compared to the wild-type strain. ..
  12. Kaminski P, Mandon K, Arigoni F, Desnoues N, Elmerich C. Regulation of nitrogen fixation in Azorhizobium caulinodans: identification of a fixK-like gene, a positive regulator of nifA. Mol Microbiol. 1991;5:1983-91 pubmed
    ..A model of regulation, based on these data, is presented and might explain the unusual ability of A. caulinodans to fix nitrogen both under symbiotic conditions and in the free-living state. ..
  13. Msadek T, Kunst F, Rapoport G. MecB of Bacillus subtilis, a member of the ClpC ATPase family, is a pleiotropic regulator controlling competence gene expression and growth at high temperature. Proc Natl Acad Sci U S A. 1994;91:5788-92 pubmed
    ..In response to an unknown signal, active ComK would accumulate through a positive feedback loop, leading to expression of competence genes allowing DNA uptake. ..
  14. Pugsley A, Francetic O. Protein secretion in Escherichia coli K-12: dead or alive?. Cell Mol Life Sci. 1998;54:347-52 pubmed
  15. Rowe Magnus D, Guerout A, Mazel D. Bacterial resistance evolution by recruitment of super-integron gene cassettes. Mol Microbiol. 2002;43:1657-69 pubmed
    ..These results demonstrate that otherwise phenotypically sensitive strains may still be a genetic source for the evolution of resistance to clinically relevant antibiotics through integron-mediated recombination events...
  16. Nora T, Lomma M, Gomez Valero L, Buchrieser C. Molecular mimicry: an important virulence strategy employed by Legionella pneumophila to subvert host functions. Future Microbiol. 2009;4:691-701 pubmed publisher
    ..Collectively, these data have shed new light on the virulence strategies of L. pneumophila, a major aspect of which is molecular mimicry. ..
  17. Allaoui A, Mounier J, Pr vost M, Sansonetti P, Parsot C. icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread. Mol Microbiol. 1992;6:1605-16 pubmed
    ..These results indicate that IcsB is involved in the lysis of the protrusions, a step necessary for intercellular spread...
  18. Bachellier S, Clement J, Hofnung M, Gilson E. Bacterial interspersed mosaic elements (BIMEs) are a major source of sequence polymorphism in Escherichia coli intergenic regions including specific associations with a new insertion sequence. Genetics. 1997;145:551-62 pubmed
    ..Unlike BIMEs, IS 1397 is not detected in all E. coli isolates. Possible relationships between the presence of this IS element and the evolution of BIMEs are discussed. ..
  19. Geissmann T, Touati D. Hfq, a new chaperoning role: binding to messenger RNA determines access for small RNA regulator. EMBO J. 2004;23:396-405 pubmed
    ..Thus, Hfq is a critical chaperone in vivo and in vitro, changing the folding of the target mRNA to make it subject to the small RNA regulator. ..
  20. Ruimy R, Armand Lefevre L, Barbier F, Ruppe E, Cocojaru R, Mesli Y, et al. Comparisons between geographically diverse samples of carried Staphylococcus aureus. J Bacteriol. 2009;191:5577-83 pubmed publisher
    ..Phylogenetic analysis revealed a highly divergent and uncharacterized genotype (ST1223) within Cambodia. This lineage is related to CC75, which has previously been observed only in remote aboriginal populations in northern Australia. ..
  21. Laalami S, Sacerdot C, Vachon G, Mortensen K, Sperling Petersen H, Cenatiempo Y, et al. Structural and functional domains of E coli initiation factor IF2. Biochimie. 1991;73:1557-66 pubmed
    ..Here we review evidence which indicates the functional importance of the different structural domains of IF2, emphasizing new information obtained by in vivo experiments. ..
  22. Debarbouille M, Martin Verstraete I, Kunst F, Rapoport G. The Bacillus subtilis sigL gene encodes an equivalent of sigma 54 from gram-negative bacteria. Proc Natl Acad Sci U S A. 1991;88:9092-6 pubmed
    ..These results indicate that the sigL gene encodes an equivalent of the sigma 54 factor in B. subtilis, to our knowledge, the first of this type to be identified in Gram-positive bacteria. ..
  23. Gilson E, Perrin D, Hofnung M. DNA polymerase I and a protein complex bind specifically to E. coli palindromic unit highly repetitive DNA: implications for bacterial chromosome organization. Nucleic Acids Res. 1990;18:3941-52 pubmed
    ..The other activity contained at least five polypeptides. Its binding to PU DNA sequences was confirmed by native gel electrophoresis. Implications for the possible origin and functions of PU are discussed. ..
  24. Bonnefoy E, Almeida A, Rouviere Yaniv J. Lon-dependent regulation of the DNA binding protein HU in Escherichia coli. Proc Natl Acad Sci U S A. 1989;86:7691-5 pubmed
  25. Heym B, Alzari P, Honor N, Cole S. Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis. Mol Microbiol. 1995;15:235-45 pubmed
    ..The second group comprises a frequently occurring amino acid substitution and a single mutation that are both located in the C-terminal domain but do not noticeably alter either enzyme activity or heat stability...
  26. Cruz Ramos H, Boursier L, Moszer I, Kunst F, Danchin A, Glaser P. Anaerobic transcription activation in Bacillus subtilis: identification of distinct FNR-dependent and -independent regulatory mechanisms. EMBO J. 1995;14:5984-94 pubmed
    ..Thus induction of genes involved in anaerobic respiration requires in B.subtilis at least two levels of regulation: activation of fnr transcription and activation of FNR to induce transcription of FNR-dependent promoters. ..
  27. Joutel A, Ducros A, Alamowitch S, Cruaud C, Domenga V, Marechal E, et al. A human homolog of bacterial acetolactate synthase genes maps within the CADASIL critical region. Genomics. 1996;38:192-8 pubmed
  28. Demers B, Sansonetti P, Parsot C. Induction of type III secretion in Shigella flexneri is associated with differential control of transcription of genes encoding secreted proteins. EMBO J. 1998;17:2894-903 pubmed publisher
  29. Arthur M, Depardieu F, Cabanie L, Reynolds P, Courvalin P. Requirement of the VanY and VanX D,D-peptidases for glycopeptide resistance in enterococci. Mol Microbiol. 1998;30:819-30 pubmed
    ..Thus, VanX and VanY had non-overlapping functions involving the hydrolysis of D-Ala-D-Ala and the removal of D-Ala from membrane-bound lipid intermediates respectively. ..
  30. Mavris M, Page A, Tournebize R, Demers B, Sansonetti P, Parsot C. Regulation of transcription by the activity of the Shigella flexneri type III secretion apparatus. Mol Microbiol. 2002;43:1543-53 pubmed
    ..This suggests that the activity of secretion is sensed by the presence of free IpgC, which acts as a coactivator to allow MxiE to activate transcription at its target promoters...
  31. Vignon G, Köhler R, Larquet E, Giroux S, Prevost M, Roux P, et al. Type IV-like pili formed by the type II secreton: specificity, composition, bundling, polar localization, and surface presentation of peptides. J Bacteriol. 2003;185:3416-28 pubmed
    ..Abnormally long pili that extend beyond the outer membrane are produced only when pilus length control and retraction are deregulated by overproduction of the major pseudopilus subunit (PulG). ..
  32. Slamti L, Perchat S, Gominet M, Vilas B as G, Fouet A, Mock M, et al. Distinct mutations in PlcR explain why some strains of the Bacillus cereus group are nonhemolytic. J Bacteriol. 2004;186:3531-8 pubmed publisher
    ..We also found that the plcR genes of three B. anthracis strains belonging to different phylogenetic groups contained the same nonsense mutation, suggesting that this mutation is a distinctive trait of this species...
  33. Kim D, Lenzen G, Page A, Legrain P, Sansonetti P, Parsot C. The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes. Proc Natl Acad Sci U S A. 2005;102:14046-51 pubmed
    ..This finding indicates that OspG negatively controls the host innate response induced by S. flexneri upon invasion of the epithelium. ..
  34. Davison S, Couture Tosi E, Candela T, Mock M, Fouet A. Identification of the Bacillus anthracis (gamma) phage receptor. J Bacteriol. 2005;187:6742-9 pubmed
    ..B. thuringiensis 97-27, a strain which, by sequence analysis, is predicted to harbor a GamR-like protein, is resistant to the phage but nevertheless displays phage binding...
  35. Courvalin P. Vancomycin resistance in gram-positive cocci. Clin Infect Dis. 2006;42 Suppl 1:S25-34 pubmed
    ..The diversity, regulation, evolution, and recent dissemination of methicillin-resistant Staphylococcus aureus are then discussed. ..
  36. Aires J, Doucet Populaire F, Butel M. Tetracycline resistance mediated by tet(W), tet(M), and tet(O) genes of Bifidobacterium isolates from humans. Appl Environ Microbiol. 2007;73:2751-4 pubmed
    ..tet(W) and tet(M) were found in 26 and 7%, respectively, of the Bifidobacterium isolates, and one isolate contained both genes. Chromosomal DNA hybridization showed that there was one chromosomal copy of tet(W) and/or tet(M)...
  37. Veziris N, Martin C, Brossier F, Bonnaud F, Denis F, Aubry A. Treatment failure in a case of extensively drug-resistant tuberculosis associated with selection of a GyrB mutant causing fluoroquinolone resistance. Eur J Clin Microbiol Infect Dis. 2007;26:423-5 pubmed
  38. Haentjens Sitri J, Allemand F, Springer M, Chiaruttini C. A competition mechanism regulates the translation of the Escherichia coli operon encoding ribosomal proteins L35 and L20. J Mol Biol. 2008;375:612-25 pubmed
    ..We show that the pseudoknot, which is known to be essential for L20 binding and regulation, also enhances 30S binding to mRNA as if this structure is specifically recognised by the ribosome. ..
  39. Sacquin Mora S, Sebban P, Derrien V, Frick B, Lavery R, Alba Simionesco C. Probing the flexibility of the bacterial reaction center: the wild-type protein is more rigid than two site-specific mutants. Biochemistry. 2007;46:14960-8 pubmed
    ..L212Glu, which is systematically conserved in all photosynthetic bacteria, seems to be one of the key residues that exerts a distant control over the rigidity of the core of the protein. ..
  40. Delevoye C, Nilges M, Dehoux P, Paumet F, Perrinet S, Dautry Varsat A, et al. SNARE protein mimicry by an intracellular bacterium. PLoS Pathog. 2008;4:e1000022 pubmed publisher
    ..Moreover, point mutations in the central layer of IncA SNARE-like motifs resulted in the loss of binding to host SNAREs. Altogether, our data demonstrate for the first time mimicry of the SNARE motif by a bacterium. ..
  41. Rusniok C, Vallenet D, Floquet S, Ewles H, Mouzé Soulama C, Brown D, et al. NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis. Genome Biol. 2009;10:R110 pubmed publisher
  42. Servet C, Ghelis T, Richard L, Zilberstein A, Savoure A. Proline dehydrogenase: a key enzyme in controlling cellular homeostasis. Front Biosci (Landmark Ed). 2012;17:607-20 pubmed
  43. Meinzer U, Barreau F, Esmiol Welterlin S, Jung C, Villard C, Léger T, et al. Yersinia pseudotuberculosis effector YopJ subverts the Nod2/RICK/TAK1 pathway and activates caspase-1 to induce intestinal barrier dysfunction. Cell Host Microbe. 2012;11:337-51 pubmed publisher
    ..Thus, YopJ alters intestinal permeability and promotes the dissemination of Yersinia as well as commensal bacteria by exploiting the mucosal inflammatory response...
  44. Govind R, Dupuy B. Secretion of Clostridium difficile toxins A and B requires the holin-like protein TcdE. PLoS Pathog. 2012;8:e1002727 pubmed publisher
    ..TcdE appears to be the first example of a bacterial protein that releases toxins into the environment by a phage-like system...
  45. Bonazzi M, Kühbacher A, Toledo Arana A, Mallet A, Vasudevan L, Pizarro Cerda J, et al. A common clathrin-mediated machinery co-ordinates cell-cell adhesion and bacterial internalization. Traffic. 2012;13:1653-66 pubmed publisher
  46. Rebuffat S. Microcins in action: amazing defence strategies of Enterobacteria. Biochem Soc Trans. 2012;40:1456-62 pubmed publisher
    ..They offer new and promising tracks for further design and engineering of novel efficient antibiotics. ..
  47. Collot M, Wilms C, Bentkhayet A, Marcaggi P, Couchman K, Charpak S, et al. CaRuby-Nano: a novel high affinity calcium probe for dual color imaging. elife. 2015;4: pubmed publisher
    ..We tested the new indicator using in vitro and in vivo experiments demonstrating the high sensitivity of CaRuby-Nano as well as its power in dual color imaging experiments. ..
  48. Mazodier P, Guglielmi G, Davies J, Thompson C. Characterization of the groEL-like genes in Streptomyces albus. J Bacteriol. 1991;173:7382-6 pubmed
    ..At least two groEL-like genes were present in all 12 Streptomyces species tested; they were not closely linked in the genome. groEL1, but not groEL2, was adjacent to a groES-like gene. ..
  49. Kaminski P, Elmerich C. Involvement of fixLJ in the regulation of nitrogen fixation in Azorhizobium caulinodans. Mol Microbiol. 1991;5:665-73 pubmed
    ..Using pnifH-lacZ and pnifA-lacZ fusions, it was shown that the FixLJ products controlled the expression of nifH and nifA in bacteria grown in the free-living state. ..
  50. Raibaud O, Vidal Ingigliardi D, Richet E. A complex nucleoprotein structure involved in activation of transcription of two divergent Escherichia coli promoters. J Mol Biol. 1989;205:471-85 pubmed
    ..We propose a model for the nucleoprotein structure that might be involved in transcription activation at these divergent promoters. ..
  51. Honor N, Bergh S, Chanteau S, Doucet Populaire F, Eiglmeier K, Garnier T, et al. Nucleotide sequence of the first cosmid from the Mycobacterium leprae genome project: structure and function of the Rif-Str regions. Mol Microbiol. 1993;7:207-14 pubmed
    ..This finding may well be significant as M. leprae, an intracellular pathogen, lives within macrophages...
  52. Betton J, Boscus D, Missiakas D, Raina S, Hofnung M. Probing the structural role of an alpha beta loop of maltose-binding protein by mutagenesis: heat-shock induction by loop variants of the maltose-binding protein that form periplasmic inclusion bodies. J Mol Biol. 1996;262:140-50 pubmed
    ..We found that the extent of formation of inclusion bodies in the periplasm of E. coli, from misfolded loop variant MBPs, correlated with the level of heat-shock response regulated by the alternate heat-shock sigma factor, sigma 24...
  53. Arthur M, Depardieu F, Gerbaud G, Galimand M, Leclercq R, Courvalin P. The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction. J Bacteriol. 1997;179:97-106 pubmed
    ..Activation of the VanR response regulator in the absence of VanS may involve autophosphorylation of VanR with acetyl phosphate or phosphorylation by a heterologous histidine protein kinase...
  54. Grillot Courvalin C, Goussard S, Huetz F, Ojcius D, Courvalin P. Functional gene transfer from intracellular bacteria to mammalian cells. Nat Biotechnol. 1998;16:862-6 pubmed
    ..Expression of the acquired genes occurs in both dividing and quiescent cells. The only requirement for bacteria to transfer genetic material into nonprofessional phagocytic cells and macrophages is the ability to invade the host cell. ..
  55. Nassif X. Genomics of Neisseria meningitidis. Int J Med Microbiol. 2002;291:419-23 pubmed
    ..This review will address the new possibilities offered by the recent availability of meningococcal genome sequences. ..
  56. Boccara M, Mills C, Zeier J, Anzi C, Lamb C, Poole R, et al. Flavohaemoglobin HmpX from Erwinia chrysanthemi confers nitrosative stress tolerance and affects the plant hypersensitive reaction by intercepting nitric oxide produced by the host. Plant J. 2005;43:226-37 pubmed
  57. Chaput C, Ecobichon C, Cayet N, Girardin S, Werts C, Guadagnini S, et al. Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape. PLoS Pathog. 2006;2:e97 pubmed publisher
    ..pylori infection...
  58. Coornaert A, Lu A, Mandin P, Springer M, Gottesman S, Guillier M. MicA sRNA links the PhoP regulon to cell envelope stress. Mol Microbiol. 2010;76:467-79 pubmed publisher
    ..In addition, we found that Hfq strongly affects the expression of phoP independently of MicA, raising the possibility that even more sRNAs, which remain to be identified, could regulate PhoPQ synthesis. ..
  59. Beaufort N, Corvazier E, Hervieu A, Choqueux C, Dussiot M, Louedec L, et al. The thermolysin-like metalloproteinase and virulence factor LasB from pathogenic Pseudomonas aeruginosa induces anoikis of human vascular cells. Cell Microbiol. 2011;13:1149-67 pubmed publisher
    ..Thus, among P. aeruginosa-secreted metalloproteinases, LasB can induce vascular cell anoikis through simultaneous proteolysis of ECM components and cell receptors, suggesting the uPAR-vitronectin axis as a major target in this process. ..
  60. Norel F, Pisano M, Nicoli J, Popoff M. Nucleotide sequence of the plasmid-borne virulence gene mkfA encoding a 28 kDa polypeptide from Salmonella typhimurium. Res Microbiol. 1989;140:263-5 pubmed
  61. Maucuer A, Camonis J, Sobel A. Stathmin interaction with a putative kinase and coiled-coil-forming protein domains. Proc Natl Acad Sci U S A. 1995;92:3100-4 pubmed
    ..The molecular and biological characterization of KIS, CC1, and CC2 proteins will give further insights into the molecular functions and mechanisms of action of stathmin as a relay of integrated intracellular regulatory pathways. ..
  62. Lim E, Rauzier J, Timm J, Torrea G, Murray A, Gicquel B, et al. Identification of mycobacterium tuberculosis DNA sequences encoding exported proteins by using phoA gene fusions. J Bacteriol. 1995;177:59-65 pubmed
    ..This approach thus appears to identify sequences directing protein export, and we expect that more extensive screening of such libraries will lead to a better understanding of protein export in M. tuberculosis. ..
  63. Calogero S, Gardan R, Glaser P, Schweizer J, Rapoport G, Debarbouille M. RocR, a novel regulatory protein controlling arginine utilization in Bacillus subtilis, belongs to the NtrC/NifA family of transcriptional activators. J Bacteriol. 1994;176:1234-41 pubmed
    ..After LevR, RocR is the second example of an activator stimulating sigma 54-dependent promoters in gram-positive bacteria. ..
  64. Dumay V, Danchin A, Crasnier M. Regulation of Escherichia coli adenylate cyclase activity during hexose phosphate transport. Microbiology. 1996;142 ( Pt 3):575-83 pubmed
    ..We present data indicating that Glc6P per se or its degradation is unlikely to be responsible for the low cAMP level. It is concluded that the level of cAMP in the cell is determined by the flux of Glc6P through UhpT. ..
  65. Camus A, Kress C, Babinet C, Barra J. Unexpected behavior of a gene trap vector comprising a fusion between the Sh ble and the lacZ genes. Mol Reprod Dev. 1996;45:255-63 pubmed
    ..Germline chimeras were subsequently obtained and 15 mouse lines have been established. Intercrosses of animals heterozygous for the insertion revealed a mutant phenotype in several lines. ..
  66. Chiaruttini C, Milet M, Springer M. Translational coupling by modulation of feedback repression in the IF3 operon of Escherichia coli. Proc Natl Acad Sci U S A. 1997;94:9208-13 pubmed
    ..The result is a novel type of translational coupling, where unfolding of the pseudoknot by ribosomes translating IF3 does not increase expression of L35 directly, but alleviates its repression by L20. ..
  67. De Reuse H, Taha M. RegF, an SspA homologue, regulates the expression of the Neisseria gonorrhoeae pilE gene. Res Microbiol. 1997;148:289-303 pubmed publisher
    ..gonorrhoeae, RegF acts as a negative regulator of pilE transcription, and (ii) in E. coli, RegF increases pilE transcription by preventing sigma 54-associated steric hindrance at pilE promoters described previously...
  68. Possot O, Vignon G, Bomchil N, Ebel F, Pugsley A. Multiple interactions between pullulanase secreton components involved in stabilization and cytoplasmic membrane association of PulE. J Bacteriol. 2000;182:2142-52 pubmed
  69. Wolff N, Sapriel G, Bodenreider C, Chaffotte A, Delepelaire P. Antifolding activity of the SecB chaperone is essential for secretion of HasA, a quickly folding ABC pathway substrate. J Biol Chem. 2003;278:38247-53 pubmed
    ..Refolding of both mutants was much slower than that of wild-type HasA and they were secreted essentially independently of SecB. We conclude that SecB has mainly an antifolding function in the HasA ABC secretion pathway. ..
  70. Raibaud S, Vachette P, Guillier M, Allemand F, Chiaruttini C, Dardel F. How bacterial ribosomal protein L20 assembles with 23 S ribosomal RNA and its own messenger RNA. J Biol Chem. 2003;278:36522-30 pubmed
  71. Sabet C, Lecuit M, Cabanes D, Cossart P, Bierne H. LPXTG protein InlJ, a newly identified internalin involved in Listeria monocytogenes virulence. Infect Immun. 2005;73:6912-22 pubmed publisher
    ..In conclusion, this postgenomic approach identified InlJ as a new virulence factor among the proteins belonging to the internalin family in L. monocytogenes...
  72. Helaine S, Dyer D, Nassif X, Pelicic V, Forest K. 3D structure/function analysis of PilX reveals how minor pilins can modulate the virulence properties of type IV pili. Proc Natl Acad Sci U S A. 2007;104:15888-93 pubmed
  73. Matta M, Gousseff M, Monsel F, Poyart C, Diebold B, Podglajen I, et al. First case of Streptococcus oligofermentans endocarditis determined based on sodA gene sequences after amplification directly from valvular samples. J Clin Microbiol. 2009;47:855-6 pubmed publisher
    ..It was responsible for the endocarditis and left forearm abscess of a 43-year-old woman. Identification was made using molecular techniques performed directly from valvular and surgical samples. ..
  74. Falord M, Mäder U, Hiron A, Debarbouille M, Msadek T. Investigation of the Staphylococcus aureus GraSR regulon reveals novel links to virulence, stress response and cell wall signal transduction pathways. PLoS ONE. 2011;6:e21323 pubmed publisher
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    ..A null mutant, constructed by disruption of nrfA, exhibited the same phenotype as the missense mutant. Thus, an additional factor can be added to the already complex system of nifA regulation in A. caulinodans...
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