Experts and Doctors on transposases in Toulouse, Languedoc Roussillon Midi Pyrénées, France
Locale: Toulouse, Languedoc Roussillon Midi Pyrénées, France
Roussigne M, Kossida S, Lavigne A, Clouaire T, Ecochard V, Glories A, et al
. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Trends Biochem Sci. 2003;28:66-9 pubmed
..Our results suggest that the THAP domain is a novel example of a DBD that is shared between cellular proteins and transposases from mobile genomic parasites. ..
Betermier M, Lefrère V, Koch C, Alazard R, Chandler M. The Escherichia coli protein, Fis: specific binding to the ends of phage Mu DNA and modulation of phage growth. Mol Microbiol. 1989;3:459-68 pubmed
..Thus, Fis may modulate Mu growth by influencing the binding of transposase, or other proteins, to the transposase binding site(s), in a way similar to its influence on Xis binding in phage lambda. ..
Berrada S, Fournier D. Transposition-mediated transcriptional overexpression as a mechanism of insecticide resistance. Mol Gen Genet. 1997;256:348-54 pubmed
..This strain had only one extra Ace gene, which overexpressed acetylcholinesterase. Thus, following transposition, resistance resulted from the overexpression of a single copy of the gene and not from gene amplification. ..
Prère M, Canal I, Wills N, Atkins J, Fayet O. The interplay of mRNA stimulatory signals required for AUU-mediated initiation and programmed -1 ribosomal frameshifting in decoding of transposable element IS911. J Bacteriol. 2011;193:2735-44 pubmed publisher
..Because of its effect on frameshifting, the Shine-Dalgarno sequence is an important determinant of the level of transposase in IS911-containing cells, and hence of the frequency of transposition. ..