Experts and Doctors on humans in Toulouse, Languedoc Roussillon Midi Pyrénées, France


Locale: Toulouse, Languedoc Roussillon Midi Pyrénées, France
Topic: humans

Top Publications

  1. Lazorthes Y, Bes J, Sagen J, Tafani M, Tkaczuk J, Sallerin B, et al. Transplantation of human chromaffin cells for control of intractable cancer pain. Acta Neurochir Suppl. 1995;64:97-100 pubmed
    ..A progressive decrease in metenkephalin release was observed from 2 to 4 months after the transplantation. Two patients with a long-term follow-up (8 and 12 months) needed another intrathecal chromaffin cell graft. ..
  2. Millevoi S, Loulergue C, Dettwiler S, Karaa S, Keller W, Antoniou M, et al. An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries. EMBO J. 2006;25:4854-64 pubmed
    ..These results therefore uncover a direct role of the U2AF 65/CF I(m) 59 interaction in the functional coordination of splicing and 3' end processing. ..
  3. Cammas A, Pileur F, Bonnal S, Lewis S, Leveque N, Holcik M, et al. Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs. Mol Biol Cell. 2007;18:5048-59 pubmed
    ..Our data highlight a new way to regulate protein synthesis in eukaryotes through the subcellular relocalization of a nuclear mRNA-binding protein. ..
  4. Sarrabayrouse G, Pich C, Moriez R, Armand Labit V, Rochaix P, Favre G, et al. Melanoma cells treated with GGTI and IFN-gamma allow murine vaccination and enhance cytotoxic response against human melanoma cells. PLoS ONE. 2010;5:e9043 pubmed publisher
  5. Delrieu J, Piau A, Caillaud C, Voisin T, Vellas B. Managing cognitive dysfunction through the continuum of Alzheimer's disease: role of pharmacotherapy. CNS Drugs. 2011;25:213-26 pubmed publisher
    ..There is currently insufficient evidence for recommending combination therapy in Alzheimer's disease. ..
  6. Galiacy S, Froment C, Mouton Barbosa E, Erraud A, Chaoui K, Desjardins L, et al. Deeper in the human cornea proteome using nanoLC-Orbitrap MS/MS: An improvement for future studies on cornea homeostasis and pathophysiology. J Proteomics. 2011;75:81-92 pubmed publisher
  7. Schieber A, Kelly Irving M, Delpierre C, Lepage B, Bensafi A, Afrite A, et al. Is perceived social distance between the patient and the general practitioner related to their disagreement on patient's health status?. Patient Educ Couns. 2013;91:97-104 pubmed publisher
    ..Physicians need to be conscious that their own perception influences the quality of the interaction with their patients, potentially resulting in unequal health care trajectories. ..
  8. Montastruc F, Gardette V, Cantet C, Piau A, Lapeyre Mestre M, Vellas B, et al. Potentially inappropriate medication use among patients with Alzheimer disease in the REAL.FR cohort: be aware of atropinic and benzodiazepine drugs!. Eur J Clin Pharmacol. 2013;69:1589-97 pubmed publisher
    ..They also indicate that the characteristics of the disease and the pharmacodynamic/pharmacokinetic profile of the drugs prescribed are not sufficiently taken into account by physicians when prescribing for AD patients. ..
  9. Aubry K, Vergez S, De Mones E, Moriniere S, Choussy O, Malard O, et al. Morbidity and mortality revue of the French group of transoral robotic surgery: a multicentric study. J Robot Surg. 2016;10:63-7 pubmed publisher
    ..TORS is a safe technique for the treatment of head and neck tumors. We identified some risk factors for complications which should systematically be studied in order to reduce its morbidity. ..

More Information

Publications546 found, 100 shown here

  1. Quang N, Pestourie C, Cibiel A, Ducongé F. How to measure the affinity of aptamers for membrane proteins expressed on the surface of living adherent cells. Methods. 2016;97:35-43 pubmed publisher
    ..Relevant issues are discussed including the labeling of aptamers, the cells preparation, the incubation, the washings, the use of non-specific competitors, the data analysis and finally the reporting. ..
  2. Lhermusier T, Severin S, Van Rothem J, Garcia C, Bertrand Michel J, Le Faouder P, et al. ATP-binding cassette transporter 1 (ABCA1) deficiency decreases platelet reactivity and reduces thromboxane A2 production independently of hematopoietic ABCA1. J Thromb Haemost. 2016;14:585-95 pubmed publisher
    ..Absence of ABCA1 and low HDL level induce reduction of platelet reactivity by decreasing positive feedback loops, particularly TXA2 production through a hematopoietic ABCA1-independent mechanism. ..
  3. Wahlgren N, Moreira T, Michel P, Steiner T, Jansen O, Cognard C, et al. Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN. Int J Stroke. 2016;11:134-47 pubmed publisher
    ..The statement is supported by ESO, European Society of Minimally Invasive Neurological Therapy (ESMINT), European Society of Neuroradiology (ESNR), and European Academy of Neurology (EAN). ..
  4. Corpet D, Pierre F. Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. Cancer Epidemiol Biomarkers Prev. 2003;12:391-400 pubmed
  5. Le Cabec V, Emorine L, Toesca I, Cougoule C, Maridonneau Parini I. The human macrophage mannose receptor is not a professional phagocytic receptor. J Leukoc Biol. 2005;77:934-43 pubmed
    ..Our new expression vector could represent a useful tool to study the receptor and its partnership further. ..
  6. Mansuy J, Bendall R, Legrand Abravanel F, Saune K, Miedouge M, Ellis V, et al. Hepatitis E virus antibodies in blood donors, France. Emerg Infect Dis. 2011;17:2309-12 pubmed publisher
    ..5% of voluntary blood donors in southwestern France. This finding suggests HEV is highly endemic to this region. The high HEV prevalence may reflect local dietary practices, such as eating uncooked pork and game products...
  7. Chaput B, Nouaille de Gorce H, Courtade Saidi M, Apredoaei C, Rongieres M, Chavoin J, et al. [The role of a systematic second look at 48-72 hours in high-pressure injection injuries to the hand: a retrospective study]. Chir Main. 2012;31:250-5 pubmed publisher
    ..This second debridement allows excision of the newly formed necrosis and to evacuate the remaining toxic residues. Finally, patients reported good functional outcome. ..
  8. Danton A, Montastruc F, Sommet A, Durrieu G, Bagheri H, Bondon Guitton E, et al. Importance of cytochrome P450 (CYP450) in adverse drug reactions due to drug-drug interactions: a PharmacoVigilance study in France. Eur J Clin Pharmacol. 2013;69:885-8 pubmed publisher
    ..All interactions involved CYP inhibitors, mainly for CYP3A4/5. The percentage of ADRs reported in the pharmacovigilance database and related to CYP450-induced DDIs appears to be relatively low (~ 1-2 %). ..
  9. Dent E, Hoogendijk E. Psychosocial resources: moderators or mediators of frailty outcomes?. J Am Med Dir Assoc. 2015;16:258-9 pubmed publisher
  10. Olivier Abbal P. Measuring the preventability of adverse drug reactions in France: A 2015 overview. Therapie. 2016;71:195-202 pubmed publisher
    ..Thus, assessing medical preventability should address the causes of ADRs and not the responsibility of healthcare professionals. Finally, certain ideas are proposed to improve the French scale and pursue its validation. ..
  11. Gong F, Clouaire T, Aguirrebengoa M, Legube G, Miller K. Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair. J Cell Biol. 2017;216:1959-1974 pubmed publisher
    ..Thus, this study identifies a crucial function for KDM5A in demethylating H3K4 to allow ZMYND8-NuRD to operate within damaged chromatin to repair DSBs. ..
  12. Mantienne C, Albucher J, Catalaa I, Sevely A, Cognard C, Manelfe C. MRI in Lyme disease of the spinal cord. Neuroradiology. 2001;43:485-8 pubmed
    ..Vasculitis is probably the major mechanism. MRI findings are nonspecific and the diagnosis is given by serum and CSF analyses. Early treatment with antibiotics and high doses steroids may result in complete recovery, as in this case. ..
  13. Lamant L, de Reynies A, Duplantier M, Rickman D, Sabourdy F, Giuriato S, et al. Gene-expression profiling of systemic anaplastic large-cell lymphoma reveals differences based on ALK status and two distinct morphologic ALK+ subtypes. Blood. 2007;109:2156-64 pubmed
    ..Once confirmed on a larger number of patients, the results of the present study could be used for clinical and therapeutic management of patients at the time of diagnosis. ..
  14. Bounes V, Dehours E, Houze Cerfon V, Vallé B, Lipton R, Ducassé J. Quality of publications in emergency medicine. Am J Emerg Med. 2013;31:297-301 pubmed publisher
    ..Emergency medicine research volume, quality, and grants activity must increase in order for EM to progress within academic medicine. ..
  15. Didierlaurent D, Ribes S, Caselles O, Jaudet C, Cazalet J, Batatia H, et al. A new respiratory gating device to improve 4D PET/CT. Med Phys. 2013;40:032501 pubmed publisher
    ..Future works will focus on patients where the authors expect a significant improvement of specificity and sensitivity of PET/CT examinations. ..
  16. Soto M, van Kan G, Nourhashemi F, Gillette Guyonnet S, Cesari M, Cantet C, et al. Angiotensin-converting enzyme inhibitors and Alzheimer's disease progression in older adults: results from the Réseau sur la Maladie d'Alzheimer Français cohort. J Am Geriatr Soc. 2013;61:1482-8 pubmed publisher
    ..9 vs 9.7 ± 0.4; P = .03). The use of ACE-Is in older adults with AD is associated with a slower rate of cognitive decline independent of hypertension. Future research is needed to explore the role of ACE-Is in long-term AD progression. ..
  17. Jean C, Tollon Y, Raynaud Messina B, Wright M. The mammalian interphase centrosome: two independent units maintained together by the dynamics of the microtubule cytoskeleton. Eur J Cell Biol. 1999;78:549-60 pubmed
  18. Girard J, Baekkevold E, Feliu J, Brandtzaeg P, Amalric F. Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules. Proc Natl Acad Sci U S A. 1999;96:12772-7 pubmed
    ..Together, these results demonstrate that SUT-1 is a distinct human Na(+)-coupled sulfate transporter, likely to play a major role in sulfate incorporation in HEV. ..
  19. Clerc P, Leung Theung Long S, Wang T, Dockray G, Bouisson M, Delisle M, et al. Expression of CCK2 receptors in the murine pancreas: proliferation, transdifferentiation of acinar cells, and neoplasia. Gastroenterology. 2002;122:428-37 pubmed
    ..ElasCCK2 mice provide a model for carcinogenesis by transformation and dedifferentiation of acinar cells. ..
  20. Bohler T, Nolting J, Kamar N, Gurragchaa P, Reisener K, Glander P, et al. Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans. Ther Drug Monit. 2007;29:77-86 pubmed
    ..We conclude that these biomarkers used in whole-blood assays are suitable for PD of immune modulators in clinical trials. ..
  21. Querleu D, Gladieff L, Delannes M, Mery E, Ferron G, Rafii A. [Preservation of fertility in gynaecologic cancers]. Bull Cancer. 2008;95:487-94 pubmed publisher
    ..Young patients presenting with gynaecologic cancers must be informed about fertility preserving options whenever applicable. ..
  22. Marijon E, de Guillebon M, Bordachar P, Jacob S, Vahdat O, Sidobre L, et al. Safety of deferring the reimplantation of pacing systems after their removal for infectious complications in selected patients: a 1-year follow-up study. J Cardiovasc Electrophysiol. 2010;21:540-4 pubmed publisher
  23. Mazereeuw Hautier J, Bezio S, Mahe E, Bodemer C, Eschard C, Viseux V, et al. Segmental and nonsegmental childhood vitiligo has distinct clinical characteristics: a prospective observational study. J Am Acad Dermatol. 2010;62:945-9 pubmed publisher
    ..23% vs 0%, P = .0001). Not all patients underwent laboratory investigations. Segmental and nonsegmental types of vitiligo have distinguishing clinical characteristics. ..
  24. Tremollieres F. [Connective tissue and prolapse genesis]. Gynecol Obstet Fertil. 2010;38:388-93 pubmed publisher
    ..The better understanding of the underlying determinants of pelvic floor disorders with a special focus on genetic factors may offer new therapeutic strategies, in addition to or replacement of surgical procedures...
  25. Lefevre L, Gales A, Olagnier D, Bernad J, Perez L, Burcelin R, et al. PPAR? ligands switched high fat diet-induced macrophage M2b polarization toward M2a thereby improving intestinal Candida elimination. PLoS ONE. 2010;5:e12828 pubmed publisher
    ..In conclusion, our data demonstrate a dual benefit of PPAR? ligands because they promote mucosal defence mechanisms against GI candidiasis through M2a macrophage polarization while regulating blood glucose level. ..
  26. Delobel P, Saliou A, Nicot F, Dubois M, Trancart S, Tangre P, et al. Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure. PLoS ONE. 2011;6:e21655 pubmed publisher
    ..However the presence of minor NNRTI-resistant viruses need not always result in virological escape. NCT00122551. ..
  27. Charosky S, Guigui P, Blamoutier A, Roussouly P, Chopin D. Complications and risk factors of primary adult scoliosis surgery: a multicenter study of 306 patients. Spine (Phila Pa 1976). 2012;37:693-700 pubmed publisher
    ..Risk factors include number of instrumented vertebra, fusion to the sacrum, PSO, and preoperative pelvic tilt of 26° or more. There is a 44% risk of a new operation in the 6-year-period after the primary procedure. ..
  28. Latil A, Libon C, Templier M, Junquero D, Lantoine Adam F, Nguyen T. Hexanic lipidosterolic extract of Serenoa repens inhibits the expression of two key inflammatory mediators, MCP-1/CCL2 and VCAM-1, in vitro. BJU Int. 2012;110:E301-7 pubmed publisher
    ..These findings provide new insights into the anti-inflammatory effects of the hexanic lipidosterolic extract of Serenoa repens, Permixon®, in benign prostatic hyperplasia. ..
  29. Anastasova V, Mahalatchimy A, Rial Sebbag E, Antó Boqué J, Keil T, Sunyer J, et al. Communication of results and disclosure of incidental findings in longitudinal paediatric research. Pediatr Allergy Immunol. 2013;24:389-94 pubmed publisher
    ..As there is no consensus within European Birth cohorts how to deal with results and incidental findings, we propose a general policy. ..
  30. Fougère B, Vellas B, Billet S, Martin P, Gallucci M, Cesari M. Air Pollution modifies the association between successful and pathological aging throughout the frailty condition. Ageing Res Rev. 2015;24:299-303 pubmed publisher
    ..Evidence is presented on how air pollution can modify the bidirectional association between successful and pathological aging throughout the frailty conditions. ..
  31. Pierot L, Moret J, Turjman F, Herbreteau D, Raoult H, Barreau X, et al. WEB Treatment of Intracranial Aneurysms: Clinical and Anatomic Results in the French Observatory. AJNR Am J Neuroradiol. 2016;37:655-9 pubmed publisher
    ..6%); and aneurysm remnant, in 12/58 aneurysms (20.7%). This prospective French Observatory study showed very good safety of aneurysm treatment with the WEB, with a high rate of adequate aneurysm occlusion at 1 year (79.3%). ..
  32. Voigt S, Giulio Tonolo F, Lyons J, Kucera J, Jones B, Schneiderhan T, et al. Global trends in satellite-based emergency mapping. Science. 2016;353:247-52 pubmed publisher
    ..We present an outlook on the future use of Earth observation technology for disaster response and mitigation by putting past and current developments into context and perspective. ..
  33. Carpene C, Galitzky J, Fontana E, Atgie C, Lafontan M, Berlan M. Selective activation of beta3-adrenoceptors by octopamine: comparative studies in mammalian fat cells. Naunyn Schmiedebergs Arch Pharmacol. 1999;359:310-21 pubmed
    ..These data suggest that, among the biogenic amines metabolically related to catecholamines, octopamine can be considered as the most selective for beta3-ARs...
  34. Lacroix Triki M, Beyris L, Martel P, Marques B. Low-grade endometrial stromal sarcoma arising from sciatic nerve endometriosis. Obstet Gynecol. 2004;104:1147-9 pubmed
    ..Endometrial stromal sarcoma arising from extrauterine endometriosis is a rare and not easily diagnosed tumor. We present a case arising from sciatic nerve endometriosis in a 50-year-old woman...
  35. Audebert M, Salles B, Weinfeld M, Calsou P. Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway. J Mol Biol. 2006;356:257-65 pubmed
    ..Taken together these results reveal functional parallels between the PARP-1 and DNA-PK-dependent end-joining processes. ..
  36. Braniste V, Leveque M, Buisson Brenac C, Bueno L, Fioramonti J, Houdeau E. Oestradiol decreases colonic permeability through oestrogen receptor beta-mediated up-regulation of occludin and junctional adhesion molecule-A in epithelial cells. J Physiol. 2009;587:3317-28 pubmed publisher
    ..These findings highlight the importance of the ER beta pathway in the control of colonic paracellular transport and mucosal homeostasis. ..
  37. du Rieu M, Torrisani J, Selves J, Al Saati T, Souque A, Dufresne M, et al. MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions. Clin Chem. 2010;56:603-12 pubmed publisher
    ..Aberrant microRNA production is an early event in the development of PanIN. Our findings indicate that miR-21 warrants further investigation as a marker for early detection of PDAC. ..
  38. Ousset M, Bouquet F, Fallone F, Biard D, Dray C, Valet P, et al. Loss of ATM positively regulates the expression of hypoxia inducible factor 1 (HIF-1) through oxidative stress: Role in the physiopathology of the disease. Cell Cycle. 2010;9:2814-22 pubmed
    ..Our compelling results highlight a new link between ATM deficiency and the clinical features of the disease and provide a molecular link between ATM downregulation and the increase in tumor angiogenesis observed in human breast cancers. ..
  39. Tanne A, Neyrolles O. C-type lectins in immunity to Mycobacterium tuberculosis. Front Biosci (Schol Ed). 2011;3:1147-64 pubmed
    ..They may also favor the host, by inducing immune defenses, such as autophagy, phagosome maturation, apoptosis and various bactericidal mechanisms. ..
  40. Bras S, Martin Lannerée S, Gobert V, Augé B, Breig O, Sanial M, et al. Myeloid leukemia factor is a conserved regulator of RUNX transcription factor activity involved in hematopoiesis. Proc Natl Acad Sci U S A. 2012;109:4986-91 pubmed publisher
    ..Thus, we propose that the regulation of RUNX protein levels is a conserved feature of MLF family members that could be critical for normal and pathological blood cell development. ..
  41. Talmont F, Mouledous L, Boué J, Mollereau C, Dietrich G. Denatured G-protein coupled receptors as immunogens to generate highly specific antibodies. PLoS ONE. 2012;7:e46348 pubmed publisher
    ..This new immunizing strategy validated with three different human GPCR (μ-opioid, κ-opioid, neuropeptide FF2 receptors) might be generalized to other members of the GPCR family. ..
  42. Lugo Villarino G, Neyrolles O. Dressed not to kill: CD16+ monocytes impair immune defence against tuberculosis. Eur J Immunol. 2013;43:327-30 pubmed publisher
    ..Together with other recent reports, the article by Balboa et al. sheds new light on the function of CD16(+) monocytes in health and disease; in this commentary, we discuss the implications stemming from these findings. ..
  43. Kamar N, Rostaing L, Izopet J. Hepatitis E virus infection in immunosuppressed patients: natural history and therapy. Semin Liver Dis. 2013;33:62-70 pubmed publisher
    ..The aim of this review is to summarize the incidence, natural history, risk factors, and treatment of HEV infections in immunosuppressed patients. HEV-induced extrahepatic manifestations are described. ..
  44. Tallet J, Albaret J, Barral J. Developmental changes in lateralized inhibition of symmetric movements in children with and without Developmental Coordination Disorder. Res Dev Disabil. 2013;34:2523-32 pubmed publisher
    ..More theoretically, the specific improvement in selective inhibition of the left finger suggests a progressive development of inter-hemispheric communication during typical development that is absent or delayed in children with DCD. ..
  45. Rouzaud Laborde C, Delmas C, Mialet Perez J, Pizzinat N, Biendel Picquet C, Boudou N, et al. First evidence of increased plasma serotonin levels in Tako-Tsubo cardiomyopathy. Biomed Res Int. 2013;2013:847069 pubmed publisher
    ..The objective of our study was to investigate evidence of serotonin release from patients with TTC in comparison with patients with ST elevation myocardial infarction (STEMI) and healthy control subjects (HCS)...
  46. Joguet G, Mansuy J, Matusali G, Hamdi S, Walschaerts M, Pavili L, et al. Effect of acute Zika virus infection on sperm and virus clearance in body fluids: a prospective observational study. Lancet Infect Dis. 2017;17:1200-1208 pubmed publisher
    ..Whole blood seems to be the best specimen for Zika virus RNA detection, diagnosis, and follow-up. Agence de la Biomédecine/Agence Régionale de Santé de la Guadeloupe/Inserm-REACTing. ..
  47. Lefrère V, Vincent A, Amalric F. Drosophila melanogaster poly(A)-binding protein: cDNA cloning reveals an unusually long 3'-untranslated region of the mRNA, also present in other eukaryotic species [corrected]. Gene. 1990;96:219-25 pubmed
    ..melanogaster PABP mRNA is shown to exist also in other eukaryotes including vertebrate species. It suggests that important regulatory sequences intrinsic to the PABP mRNA are present within this 3'-untranslated region. ..
  48. Boneu B, Leger P. [Oral anticoagulant treatment: practical aspects and significance of anticoagulant clinics]. Ann Cardiol Angeiol (Paris). 2002;51:164-8 pubmed
    ..It has been reported that these structures reduce the incidence of bleeding and of thrombotic events by 3 to 4 times...
  49. Mazieres J, Antonia T, Daste G, Muro Cacho C, Berchery D, Tillement V, et al. Loss of RhoB expression in human lung cancer progression. Clin Cancer Res. 2004;10:2742-50 pubmed
    ..RhoB loss of expression occurs very frequently in lung carcinogenesis, reinforcing its putative tumor suppressive activity, and raising the value of its potential use in cancer therapy. ..
  50. Auge N, Maupas Schwalm F, Elbaz M, Thiers J, Waysbort A, Itohara S, et al. Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation. Circulation. 2004;110:571-8 pubmed
    ..These pathways may constitute a potential therapeutic target for modulating the oxLDL-induced proliferation of SMCs in atherosclerosis or restenosis. ..
  51. Aressy B, Bugler B, Valette A, Biard D, Ducommun B. Moderate variations in CDC25B protein levels modulate the response to DNA damaging agents. Cell Cycle. 2008;7:2234-40 pubmed
  52. Al Saati T, Clerc P, Hanoun N, Peuget S, Lulka H, Gigoux V, et al. Oxidative stress induced by inactivation of TP53INP1 cooperates with KrasG12D to initiate and promote pancreatic carcinogenesis in the murine pancreas. Am J Pathol. 2013;182:1996-2004 pubmed publisher
  53. Tafti M, Lammers G, Dauvilliers Y, Overeem S, Mayer G, Nowak J, et al. Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity. Sleep. 2016;39:581-7 pubmed publisher
    ..34 [1.15-1.57] P = 2.43*10(-4)). Our findings provide a genetic basis for increased susceptibility to infectious factors or an immune cytotoxic mechanism in narcolepsy, potentially targeting hypocretin neurons. ..
  54. Lacombe C, Viallard V, Schaak S, Paris H. Identification and subcellular distribution of the Gi-proteins in the enterocytic-differentiated adenocarcinoma cell-line, Caco-2. Biol Cell. 1996;88:123-9 pubmed
    ..Based upon double-labelling experiments with antibody against rough endoplasmic reticulum (RER), there is a strong possibility that intra-cellular sites of alpha i2-subunit correspond to association with RER membranes. ..
  55. Delvaux M, Louvel D, Lagier E, Scherrer B, Abitbol J, Frexinos J. The kappa agonist fedotozine relieves hypersensitivity to colonic distention in patients with irritable bowel syndrome. Gastroenterology. 1999;116:38-45 pubmed
    ..Fedotozine seems capable of reversing visceral hypersensitivity observed in these patients and could have some beneficial action on their symptoms. ..
  56. Magnaval J, Mansuy J, Villeneuve L, Cassaing S. A retrospective study of autochthonous strongyloïdiasis in Région Midi-Pyrénées (Southwestern France). Eur J Epidemiol. 2000;16:179-82 pubmed
    ..No case of larva currens was observed. These results suggest that a permanent transmission of strongyloïdiasis possibly exists in Région Midi-Pyrénées, requiring further prospective studies. ..
  57. Subra J, Cautain B, Xystrakis E, Mas M, Lagrange D, van der Heijden H, et al. The balance between CD45RChigh and CD45RClow CD4 T cells in rats is intrinsic to bone marrow-derived cells and is genetically controlled. J Immunol. 2001;166:2944-52 pubmed
    ..The identification and functional characterization of genes in these regions controlling the CD45RC(high)/CD45RC(low) Th cell subpopulations may shed light on key regulatory mechanisms of pathogenic immune responses. ..
  58. Baldin V, Pelpel K, Cazales M, Cans C, Ducommun B. Nuclear localization of CDC25B1 and serine 146 integrity are required for induction of mitosis. J Biol Chem. 2002;277:35176-82 pubmed
    ..Serine 146 phosphorylation is proposed to be a key event in the regulation of the CDC25B function in the initiation of mammalian mitosis. ..
  59. Bertrand C, Fabre N, Moulis C. A new coumarin glucoside, coumarins and alkaloids from Ruta corsica roots. Fitoterapia. 2004;75:242-4 pubmed
  60. Kamar N, Faure P, Dupuis E, Cointault O, Joseph Hein K, Durand D, et al. Villous atrophy induced by mycophenolate mofetil in renal-transplant patients. Transpl Int. 2004;17:463-7 pubmed
    ..It is mandatory to differentiate coeliac disease from MMF-induced villous atrophy because, in the latter case, a gluten-free diet is not required. ..
  61. Fontaine S, Gaches F, Lamant L, Uzan M, Bennet A, Caron P. An unusual form of Riedel's thyroiditis: a case report and review of the literature. Thyroid. 2005;15:85-8 pubmed
    ..We observed a dramatic improvement after surgery with absence of fever and normalization of inflammatory parameters. The role of EBV infection in the process of this unusual form of Riedel's thyroiditis is discussed...
  62. Depoil D, Zaru R, Guiraud M, Chauveau A, Harriague J, Bismuth G, et al. Immunological synapses are versatile structures enabling selective T cell polarization. Immunity. 2005;22:185-94 pubmed
    ..The combination of sustained signaling with preferential and rapid polarization provides a mechanism for the high sensitivity and selectivity of T cell responses. ..
  63. Vantourout P, Martinez L, Fabre A, Collet X, Champagne E. Ecto-F1-ATPase and MHC-class I close association on cell membranes. Mol Immunol. 2008;45:485-92 pubmed
    ..This demonstrates that the TCR target F1-ATPase is in close contact with MHC-I antigens which are known to control Vgamma9/Vdelta2 T cell activity through binding to natural killer inhibitory receptors. ..
  64. Roux F, Lauwers F, Oucheng N, Say B, Joly B, Gollogly J. Treatment of frontoethmoidal meningoencephalocele in Cambodia: a low-cost procedure for developing countries. J Neurosurg. 2007;107:11-21 pubmed
    ..The authors developed a low-cost humanitarian program with the goals of treating frontoethmoidal MECs, ensuring careful postoperative follow-up, and teaching Khmer surgeons how to treat these malformations...
  65. Moro C, Klimcakova E, Lafontan M, Berlan M, Galitzky J. Phosphodiesterase-5A and neutral endopeptidase activities in human adipocytes do not control atrial natriuretic peptide-mediated lipolysis. Br J Pharmacol. 2007;152:1102-10 pubmed
    ..Functional PDE-5A and NEP activities were present in human adipocytes, however these enzymes did not play a major role in the regulation of ANP-mediated lipolysis. ..
  66. Laffosse J, Abid A, Accadbled F, Knör G, Sales de Gauzy J, Cahuzac J. Surgical correction of Madelung's deformity by combined corrective radioulnar osteotomy: 14 cases with four-year minimum follow-up. Int Orthop. 2009;33:1655-61 pubmed publisher
    ..This technique provides satisfactory and encouraging results and does not compromise the surgical future of the wrist. However, longer follow-up is required to assess recurrence or possible long-term degenerative consequences...
  67. Edouard T, Grunenwald S, Gennero I, Salles J, Tauber M. Prevalence of IGF1 deficiency in prepubertal children with isolated short stature. Eur J Endocrinol. 2009;161:43-50 pubmed publisher
    ..7 years, P=0.03). The prevalence of primary IGFD was 20% in children with isolated SS. Concerning the pathophysiology, our study emphasizes that IGFD in some children may be secondary to nutritional deficiency or to maturational delay. ..
  68. de Glisezinski I, Larrouy D, Bajzova M, Koppo K, Polak J, Berlan M, et al. Adrenaline but not noradrenaline is a determinant of exercise-induced lipid mobilization in human subcutaneous adipose tissue. J Physiol. 2009;587:3393-404 pubmed publisher
    ..For the moment, it is unknown if results apply specifically to SCAT and exercise only or if conclusions could be extended to all forms of lipolysis in humans. ..
  69. Nasr N, Ruidavets J, Arnal J, Sie P, Larrue V. Association of neutrophil count with microembolization in patients with symptomatic carotid artery stenosis. Atherosclerosis. 2009;207:519-23 pubmed publisher
    ..Our findings suggest that neutrophils may play a role in the pathogenesis of stroke related to carotid atherosclerosis. ..
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