Experts and Doctors on humans in Strasbourg, Alsace Champagne Ardenne Lorraine, France


Locale: Strasbourg, Alsace Champagne Ardenne Lorraine, France
Topic: humans

Top Publications

  1. Bouvier Nav P, Benveniste P, Oelkers P, Sturley S, Schaller H. Expression in yeast and tobacco of plant cDNAs encoding acyl CoA:diacylglycerol acyltransferase. Eur J Biochem. 2000;267:85-96 pubmed
  2. Biancalana V, Caron O, Gallati S, Baas F, Kress W, Novelli G, et al. Characterisation of mutations in 77 patients with X-linked myotubular myopathy, including a family with a very mild phenotype. Hum Genet. 2003;112:135-42 pubmed
    ..The spectrum of mutations is now enlarged from the very severe classic neonatal phenotype to very mild phenotype allowing survival to the age of 67 years. ..
  3. Doi M, Hirayama J, Sassone Corsi P. Circadian regulator CLOCK is a histone acetyltransferase. Cell. 2006;125:497-508 pubmed
    ..Identification of CLOCK as a novel type of DNA binding HAT reveals that chromatin remodeling is crucial for the core clock mechanism and identifies unforeseen links between histone acetylation and cellular physiology. ..
  4. Becmeur F, Reinberg O, Dimitriu C, Moog R, Philippe P. Thoracoscopic repair of congenital diaphragmatic hernia in children. Semin Pediatr Surg. 2007;16:238-44 pubmed
    ..Criteria for eligibility need more cases to be evaluated. The advantages and disadvantages of thoracoscopy versus laparoscopy are reviewed. Nevertheless, the thoracoscopic approach seems easier. ..
  5. Deddouche S, Matt N, Budd A, Mueller S, Kemp C, Galiana Arnoux D, et al. The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila. Nat Immunol. 2008;9:1425-32 pubmed publisher
    ..We propose that this family represents an evolutionary conserved set of sensors that detect viral nucleic acids and direct antiviral responses. ..
  6. Romieu P, Gobaille S, Aunis D, Zwiller J. Injection of the neuropeptide CNP into dopaminergic rat brain areas decreases alcohol intake. Ann N Y Acad Sci. 2008;1139:27-33 pubmed publisher
    ..The results indicate that changes of cyclic GMP levels in dopaminergic rat brain areas participate in the neurobiological mechanisms underlying alcohol craving after withdrawal and/or alcohol dependence...
  7. Livolsi A, Niederhoffer N, Dali Youcef N, Rambaud C, Olexa C, Mokni W, et al. Cardiac muscarinic receptor overexpression in sudden infant death syndrome. PLoS ONE. 2010;5:e9464 pubmed publisher
    ..The present study aimed to seek vago-cardiac abnormalities in SIDS victims. The cardiac level of expression of muscarinic receptors, as well as acetylcholinesterase enzyme activity were investigated...
  8. Sauer A, Letscher Bru V, Speeg Schatz C, Touboul D, Colin J, Candolfi E, et al. In vitro efficacy of antifungal treatment using riboflavin/UV-A (365 nm) combination and amphotericin B. Invest Ophthalmol Vis Sci. 2010;51:3950-3 pubmed publisher
    ..Previous treatment with amphotericin B allowed riboflavin/UV-A effectiveness against C. albicans, Fusarium sp, and A. fumigatus. This schema might be used in the future for the treatment of keratomycosis. ..
  9. Quoix E, Zalcman G, Oster J, Westeel V, Pichon E, Lavole A, et al. Carboplatin and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-small-cell lung cancer: IFCT-0501 randomised, phase 3 trial. Lancet. 2011;378:1079-88 pubmed publisher
    ..We feel that the current treatment paradigm for these patients should be reconsidered. Intergroupe Francophone de Cancérologie Thoracique, Institut National du Cancer. ..

More Information

Publications708 found, 100 shown here

  1. Gottenberg J, Seror R, Miceli Richard C, Benessiano J, Devauchelle Pensec V, Dieude P, et al. Serum levels of beta2-microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjögren's syndrome. Data at enrollment in the prospective ASSESS cohort. PLoS ONE. 2013;8:e59868 pubmed publisher
    ..9-1187.2) pg/ml, P?=?0.01 and 2.6 (2.2-2.9) vs 2.1 (1.8-2.6) mg/l, P?=?0.04, respectively). In pSS, higher levels of beta2-microglobulin and free light chains of immunoglobulins are associated with increased systemic disease activity. ..
  2. Tromp D, Dufour A, Lithfous S, Pebayle T, Després O. Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies. Ageing Res Rev. 2015;24:232-62 pubmed publisher
    ..In this review, we will present results that attempt to characterize normal and pathological cognitive aging at multiple levels by integrating structural, behavioral, inter-individual and neuroimaging measures of episodic memory. ..
  3. Lejay A, Fang F, John R, Van J, Barr M, Thaveau F, et al. Ischemia reperfusion injury, ischemic conditioning and diabetes mellitus. J Mol Cell Cardiol. 2016;91:11-22 pubmed publisher
  4. Rasmussen U, Wolf C, Mattei M, Chenard M, Bellocq J, Chambon P, et al. Identification of a new interferon-alpha-inducible gene (p27) on human chromosome 14q32 and its expression in breast carcinoma. Cancer Res. 1993;53:4096-101 pubmed
  5. Wiorowski M, Schultz P, Perrot J, Gentine A, Debry C. Indications and results of cauterization by endoscopic approach of the sphenopalatine artery in severe posterior epistaxis. Auris Nasus Larynx. 2004;31:131-3 pubmed
    ..Cauterization by endonasal approach of the sphenopalatine artery in severe posterior epistaxis is a reliable intervention. Its role is clearly defined in our department, after failure of traditional treatments by packing methods. ..
  6. Namer I, Battaglia F, Hirsch E, Constantinesco A, Marescaux C. Subtraction ictal SPECT co-registered to MRI (SISCOM) in Sturge-Weber syndrome. Clin Nucl Med. 2005;30:39-40 pubmed
  7. Leveque D, Jehl F. Molecular pharmacokinetics of catharanthus (vinca) alkaloids. J Clin Pharmacol. 2007;47:579-88 pubmed
    ..The clinical impact of these determinants (drug disposition, drug-drug interactions) is also discussed. ..
  8. Bader M, Vitale N. Phospholipase D in calcium-regulated exocytosis: lessons from chromaffin cells. Biochim Biophys Acta. 2009;1791:936-41 pubmed publisher
    ..Moreover, multiple signaling pathways converging on PLD1 regulation have been unraveled in chromaffin cells, suggesting a complex level of regulation dependant on the physiological context. ..
  9. Eschbach J, Dupuis L. Cytoplasmic dynein in neurodegeneration. Pharmacol Ther. 2011;130:348-63 pubmed publisher
    ..Here, we critically review the evidence of dynein involvement in different neurodegenerative diseases and discuss potential underlying mechanisms. ..
  10. Bloch Zupan A, Jamet X, Etard C, Laugel V, Muller J, Geoffroy V, et al. Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects. Am J Hum Genet. 2011;89:773-81 pubmed publisher
    ..Knockdown of smoc2 in zebrafish showed pharyngeal teeth that had abnormalities reminiscent of the human phenotype. Moreover, smoc2 depletion in zebrafish affected the expression of three major odontogenesis genes: dlx2, bmp2, and pitx2. ..
  11. Bedini S, Braun F, Weibel L, Aussedat M, Pereira B, Dutheil F. Stress and salivary cortisol in emergency medical dispatchers: A randomized shifts control trial. PLoS ONE. 2017;12:e0177094 pubmed publisher
    ..07). In conclusion, the incoming emergency call shift carries particular risk for dispatchers, who have greater perceived stress and a greater increase in cortisol levels. ..
  12. Schaub M, Myslinski E, Schuster C, Krol A, Carbon P. Staf, a promiscuous activator for enhanced transcription by RNA polymerases II and III. EMBO J. 1997;16:173-81 pubmed
    ..Altogether, our results emphasize the prime importance of Staf as a novel activator for enhanced transcription of snRNA and snRNA-type genes. ..
  13. Koutnikova H, Campuzano V, Foury F, Dolle P, Cazzalini O, Koenig M. Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin. Nat Genet. 1997;16:345-51 pubmed
    ..Finally, tagging experiments demonstrate that human frataxin co-localizes with a mitochondrial protein. Friedreich's ataxia is therefore a mitochondrial disease caused by a mutation in the nuclear genome. ..
  14. Vincent F, Ceraline J, Goldblum S, Klein Soyer C, Bergerat J. A new flow cytometric method to follow DNA gap filling during nucleotide excision repair of UVc-induced damage. Cytometry. 2001;45:96-101 pubmed
    ..Practical advantages include the rapidity of the method, no need for radioactivity, and the possibility to use a second and/even a third flow marker to analyse cell cycle and heterogeneous cell populations concomitantly. ..
  15. Angenieux C, Salamero J, Fricker D, Wurtz J, Maitre B, Cazenave J, et al. Common characteristics of the human and rhesus macaque CD1e molecules: conservation of biochemical and biological properties during primate evolution. Immunogenetics. 2003;54:842-9 pubmed
  16. Leroux F. Inhibition of p450 17 as a new strategy for the treatment of prostate cancer. Curr Med Chem. 2005;12:1623-9 pubmed
    ..This paper will review the possible approaches dealing with P450 17 inhibition as a chemotherapeutic strategy in the struggle against prostate cancer. ..
  17. Malacombe M, Bader M, Gasman S. Exocytosis in neuroendocrine cells: new tasks for actin. Biochim Biophys Acta. 2006;1763:1175-83 pubmed
    ..The results cited in this review are derived primarily from investigations of the adrenal medullary chromaffin cell, a cell model that is since many years a source of information concerning the molecular machinery underlying exocytosis. ..
  18. Moser T, Dosch J, Moussaoui A, Dietemann J. Wrist ligament tears: evaluation of MRI and combined MDCT and MR arthrography. AJR Am J Roentgenol. 2007;188:1278-86 pubmed
    ..MDCT arthrography appears more accurate than MRI and MR arthrography, particularly for discerning partial tears of the scapholunate and lunotriquetral ligaments that do not necessitate surgical therapy. ..
  19. Gérard M, Krol A, Carbon P. Transcription factor hStaf/ZNF143 is required for expression of the human TFAM gene. Gene. 2007;401:145-53 pubmed
    ..Altogether, our data led to the conclusion that the promoter of the human TFAM gene harbors a complex organization with at least six transcriptional regulatory elements. ..
  20. Nithart C, Demont E, Majerus S, Leybaert J, Poncelet M, Metz Lutz M. Reading disabilities in SLI and dyslexia result from distinct phonological impairments. Dev Neuropsychol. 2009;34:296-311 pubmed publisher
  21. Benga W, Krieger S, Dimitrova M, Zeisel M, Parnot M, Lupberger J, et al. Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles. Hepatology. 2010;51:43-53 pubmed publisher
    ..These findings have important implications for understanding the HCV life cycle and the development of novel antiviral strategies targeting HCV-lipoprotein interaction...
  22. Panaro F, Piardi T, Audet M, Gheza F, Woehl Jaegle M, Portolani N, et al. Laparoscopic ultrasound-guided radiofrequency ablation as a bridge to liver transplantation for hepatocellular carcinoma: preliminary results. Transplant Proc. 2010;42:1179-81 pubmed publisher
    ..However, LTA does not increase the risk of postoperative complications. There is insufficient evidence that LTA offers any benefit when used prior to OLT either for early or for advanced HCC. ..
  23. Kessler R, Partridge M, Miravitlles M, Cazzola M, Vogelmeier C, Leynaud D, et al. Symptom variability in patients with severe COPD: a pan-European cross-sectional study. Eur Respir J. 2011;37:264-72 pubmed publisher
    ..Patient-perceived COPD symptoms vary over the day and the week, and impact on daily activities; morning being the worst time of day. The majority of patients appear not to adjust treatment when symptoms worsen. ..
  24. Gottenberg J, Dayer J, Lukas C, Ducot B, Chiocchia G, Cantagrel A, et al. Serum IL-6 and IL-21 are associated with markers of B cell activation and structural progression in early rheumatoid arthritis: results from the ESPOIR cohort. Ann Rheum Dis. 2012;71:1243-8 pubmed publisher
    ..Serum IL-6 concentration is greater in RA than in UA. Increase in serum IL-6 and IL-21 levels is associated with markers of B cell activation, and IL-6 is associated with radiographic progression in patients with RA. ..
  25. Cribier B. Medical history of the representation of rosacea in the 19th century. J Am Acad Dermatol. 2013;69:S2-14 pubmed publisher
    ..This article highlights these illustrative contributions in dermatology, and includes key images that serve as a road map to early clinical understanding of skin diseases. ..
  26. Von Grabowiecki Y, Abreu P, Blanchard O, Palamiuc L, Benosman S, Mériaux S, et al. Transcriptional activator TAp63 is upregulated in muscular atrophy during ALS and induces the pro-atrophic ubiquitin ligase Trim63. elife. 2016;5: pubmed publisher
    ..Altogether, these results suggest a novel function for p63 as a contributor to muscular atrophic processes via the regulation of multiple genes, including the muscle atrophy gene Trim63. ..
  27. Fischbach M, Schmitt C, Shroff R, Zaloszyc A, Warady B. Increasing sodium removal on peritoneal dialysis: applying dialysis mechanics to the peritoneal dialysis prescription. Kidney Int. 2016;89:761-6 pubmed publisher
    ..These findings are not explained by the current 3-pore model of peritoneal permeability and require further prospective crossover studies in adults and children for validation. ..
  28. Kintz P, Cirimele V, Sachs H, Jeanneau T, Ludes B. Testing for anabolic steroids in hair from two bodybuilders. Forensic Sci Int. 1999;101:209-16 pubmed
    ..Although not yet recognized by the International Olympic Committee, hair analysis may be a useful adjunct to conventional drug testing in urine from athletes. ..
  29. Stoll C, Sauvage P. Long-term follow-up of a girl with oro-facio-digital syndrome type I due to a mutation in the OFD 1 gene. Ann Genet. 2002;45:59-62 pubmed
    ..An older brother had hydrocephaly, bilateral optic atrophy and mental retardation. A younger sister is unaffected. A mutation, an insertion of a G leading to a frameshift in the OFD 1 gene, was identified in this patient. ..
  30. Mauvieux L, Leymarie V, Helias C, Perrusson N, Falkenrodt A, Lioure B, et al. High incidence of Hox11L2 expression in children with T-ALL. Leukemia. 2002;16:2417-22 pubmed
    ..Hence, Hox11L2 expression seems to be the most frequent abnormality in childhood T-ALL to date, comparable to the t(12;21) in child B-ALL. ..
  31. Roy C, Tuchmann C. [Scrotal ultrasonography. Part I: common non-cancerous pathologies]. J Radiol. 2003;84:581-95 pubmed
    ..When a tumoral process is suspected, surgery is required to confirm the diagnosis and provide histology. The role of MR remains under evaluation...
  32. Cluet D, Bertsch C, Beyer C, Gloeckler L, Erhardt M, Gut J, et al. Detection of human immunodeficiency virus type 1 Nef and CD4 physical interaction in living human cells by using bioluminescence resonance energy transfer. J Virol. 2005;79:8629-36 pubmed
    ..Moreover, our results clearly indicate that the dileucine motif of the CD4 cytoplasmic domain, critical for the Nef-induced CD4 down-regulation, is not implicated in the Nef/CD4 complex formation in the cellular context. ..
  33. Ingenbleek Y. The nutritional relationship linking sulfur to nitrogen in living organisms. J Nutr. 2006;136:1641S-1651S pubmed publisher
  34. Mutter D, Bouras G, Forgione A, Vix M, Leroy J, Marescaux J. Two-stage totally minimally invasive approach for acute complicated diverticulitis. Colorectal Dis. 2006;8:501-5 pubmed
    ..Two patients were not re-operated because of comorbidity and one refused surgery. A two-stage totally minimally invasive approach may be a safe alternative strategy for selected cases of acute complicated diverticulitis. ..
  35. Zeniou Meyer M, Zabari N, Ashery U, Chasserot Golaz S, Haeberle A, Demais V, et al. Phospholipase D1 production of phosphatidic acid at the plasma membrane promotes exocytosis of large dense-core granules at a late stage. J Biol Chem. 2007;282:21746-57 pubmed
    ..We propose that the underlying mechanism is related to the ability of PA to alter membrane curvature and promote hemi-fusion. ..
  36. Roth S, Raul J, Willinger R. Finite element modelling of paediatric head impact: global validation against experimental data. Comput Methods Programs Biomed. 2010;99:25-33 pubmed publisher
    ..Global validation of the model against experimental data in terms of skull deflection is performed and the model is used to simulate paediatric skull fracture coming from real-world head trauma. ..
  37. Lutz P, Kieffer B. Opioid receptors: distinct roles in mood disorders. Trends Neurosci. 2013;36:195-206 pubmed publisher
  38. Zona L, Lupberger J, Sidahmed Adrar N, Thumann C, Harris H, Barnes A, et al. HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex. Cell Host Microbe. 2013;13:302-13 pubmed publisher
    ..HRas was also found to be relevant for entry of other viruses, including influenza. Our data demonstrate that viruses exploit HRas signaling for cellular entry by compartmentalization of entry factors and receptor trafficking...
  39. Ruppert E, Lalanne L, Foucher J, Zimmermann M, Hirsch E, Vidailhet P. Electroconvulsive therapy for psychosis in a patient with epilepsy related to hypothalamic hamartoma. Epileptic Disord. 2013;15:347-51 pubmed publisher
  40. Sanchez Lopez R, Alexander C, Behrendtsen O, Breathnach R, Werb Z. Role of zinc-binding- and hemopexin domain-encoded sequences in the substrate specificity of collagenase and stromelysin-2 as revealed by chimeric proteins. J Biol Chem. 1993;268:7238-47 pubmed
    ..Rather, the zinc-binding domain confers a distinct cleavage specificity on each metalloproteinase. ..
  41. Schneider L, Ehlinger M, Stanchina C, Giacomelli M, Gicquel P, Karger C, et al. Salmonella enterica subsp. arizonae bone and joints sepsis. A case report and literature review. Orthop Traumatol Surg Res. 2009;95:237-42 pubmed publisher
    ..We carry out a recall of the complex nomenclature of Salmonella, a review of the literature and provide information on the recommended precautions for reducing the risk of transmission of Salmonella from reptiles to humans. ..
  42. Williams G, Malin M, Vremec D, Chang C, Boyd R, Benoist C, et al. Mice lacking the transcription factor CIITA--a second look. Int Immunol. 1998;10:1957-67 pubmed
    ..Second, in contrast to recent results on human cell lines, CIITA is not critically involved in the IFN-gamma-induced up-regulation of MHC class I genes. ..
  43. Stoll C, Alembik Y, Tchomakov D, Messer J, Heid E, Boehm N, et al. Severe hypernatremic dehydration in an infant with Netherton syndrome. Genet Couns. 2001;12:237-43 pubmed
    ..Molecular studies revealed a mutation in SPINK 5, encoding a serine protease inhibitor. Prenatal diagnosis was performed in the second pregnancy and showed that the fetus was equally affected. ..
  44. Sauvage P, Becmeur F, Moog R, Kauffmann I. Is one-stage ureterocele repair possible in children?. Eur Urol. 2002;42:607-13; discussion 613 pubmed
    ..When this surgery is performed on older children or adolescents, the ureteroceles will be smaller with a lower risk of sphincter damage. ..
  45. Hichri H, Stoetzel C, Laurier V, Caron S, Sigaudy S, Sarda P, et al. Testing for triallelism: analysis of six BBS genes in a Bardet-Biedl syndrome family cohort. Eur J Hum Genet. 2005;13:607-16 pubmed
    ..This study underlines the genetic heterogeneity of the BBS and the involvement of possibly unidentified genes. ..
  46. Myslinski E, Gérard M, Krol A, Carbon P. Transcription of the human cell cycle regulated BUB1B gene requires hStaf/ZNF143. Nucleic Acids Res. 2007;35:3453-64 pubmed
    ..These results demonstrate that BUB1B gene transcription is positively regulated by hStaf/ZNF143, a ubiquitously expressed factor, and that the CDE-CHR tandem element was essential for G2/M-specific transcription of the BUB1B gene. ..
  47. Stoll C, Alembik Y, Dott B, Roth M. Omphalocele and gastroschisis and associated malformations. Am J Med Genet A. 2008;146A:1280-5 pubmed publisher
    ..Malformation surveillance programs should be aware that the malformations associated with omphalocele can be often classified into a recognizable malformation syndrome or pattern (44.2%). ..
  48. Kieffer C, Cribier B, Lipsker D. Neutrophilic urticarial dermatosis: a variant of neutrophilic urticaria strongly associated with systemic disease. Report of 9 new cases and review of the literature. Medicine (Baltimore). 2009;88:23-31 pubmed publisher
  49. Pinault D. Dysfunctional thalamus-related networks in schizophrenia. Schizophr Bull. 2011;37:238-43 pubmed publisher
    ..Disruption of thalamic lateral inhibition may contribute to a lack of coordination in activity between brain regions, as observed in psychiatric disorders like schizophrenia. ..
  50. Stephenson K, Schröder C, Bertschy G, Bourgin P. Complex interaction of circadian and non-circadian effects of light on mood: shedding new light on an old story. Sleep Med Rev. 2012;16:445-54 pubmed publisher
    ..Such research could improve therapeutic management of affective disorders and influence the management of societal lighting conditions. ..
  51. Collongues N, Vermersch P. Multiple sclerosis spasticity: 'state-of-the-art' questionnaire survey of specialized healthcare professionals. Expert Rev Neurother. 2013;13:21-5 pubmed publisher
  52. Bracard S, Derelle A, Tonnelet R, Barbier C, Proust F, Anxionnat R. [Endovascular treatment of giant intracranial aneurysms]. Neurochirurgie. 2016;62:25-9 pubmed publisher
    ..Subsequently, the complex procedures increased the risk of morbidity because of ischemic complications. Despite these procedures, the risk of recurrence was high. ..
  53. Baltzinger P, Moreau F, Greget M, Bédat B, Berney T, Kessler L. Unexpected Massive Hemothorax After Pancreatic Islet Transplantation: A Case Report. Transplant Proc. 2016;48:285-7 pubmed publisher
    ..This uncommon adverse event highlights the importance of close monitoring in the first days following islet transplantation. ..
  54. Thomas P, Falcoz P, Bernard A, Le Pimpec Barthes F, Jougon J, Brouchet L, et al. Bilobectomy for lung cancer: contemporary national early morbidity and mortality outcomes. Eur J Cardiothorac Surg. 2016;49:e38-43; discussion e43 pubmed publisher
    ..Additional surgical measures to prevent pleural space complications and bronchial fistula should be encouraged with this operation. In contrast, upper bilobectomy shares more or less the same hazards as lobectomy. ..
  55. Czernichow B, Simon Assmann P, Kedinger M, Arnold C, Parache M, Marescaux J, et al. Sucrase-isomaltase expression and enterocytic ultrastructure of human colorectal tumors. Int J Cancer. 1989;44:238-44 pubmed
    ..Sucrase activity was extremely low (mean values 1.1 to 1.8 mU/mg protein) and rose only exceptionally to 17.5 mU/mg prot. ..
  56. Sarde C, Thomas J, Sadoulet H, Garnier J, Mandel J. cDNA sequence of Aldgh, the mouse homolog of the X-linked adrenoleukodystrophy gene. Mamm Genome. 1994;5:810-3 pubmed
  57. de Groot R, Auwerx J, Bourouis M, Sassone Corsi P. Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy. Oncogene. 1993;8:841-7 pubmed
    ..Here we show that the products of the sgg gene can also function as negative regulators of Jun/AP-1. ..
  58. Goichot B, Sapin R, Schlienger J. Subclinical hyperthyroidism: considerations in defining the lower limit of the thyrotropin reference interval. Clin Chem. 2009;55:420-4 pubmed publisher
    ..Recent recommendations regarding subclinical thyroid dysfunction give different advice about its management, depending on whether the TSH concentration is <0.1 mIU/L or 0.1-0.4 mIU/L...
  59. Momboisse F, Lonchamp E, Calco V, Ceridono M, Vitale N, Bader M, et al. betaPIX-activated Rac1 stimulates the activation of phospholipase D, which is associated with exocytosis in neuroendocrine cells. J Cell Sci. 2009;122:798-806 pubmed publisher
  60. Dallemagne B, Perretta S, Allemann P, Asakuma M, Marescaux J. Transgastric hybrid cholecystectomy. Br J Surg. 2009;96:1162-6 pubmed publisher
    ..Further studies are essential to evaluate the role of this new approach. ..
  61. Aslam R, Atindehou M, Lavaux T, Haikel Y, Schneider F, Metz Boutigue M. Chromogranin A-derived peptides are involved in innate immunity. Curr Med Chem. 2012;19:4115-23 pubmed
    ..Finally, we demonstrate that several antimicrobial CgA-derived peptides are able to act synergistically with antibiotics against bacteria and fungi indicating their roles in innate defense. ..
  62. Santucci R, Leveque D, Herbrecht R, Fischbach M, Gérout A, Untereiner C, et al. [Medication adverse events: Impact of pharmaceutical consultations during the hospitalization of patients]. Ann Pharm Fr. 2014;72:440-50 pubmed publisher
    ..Moreover, adding one medication increases from 14 to 30% as a risk of MAE on the population. Pharmaceutical consultations during the hospital stay could reduce significantly the number of medication adverse effects. ..
  63. Latrick C, Marek M, Ouararhni K, Papin C, Stoll I, Ignatyeva M, et al. Molecular basis and specificity of H2A.Z-H2B recognition and deposition by the histone chaperone YL1. Nat Struct Mol Biol. 2016;23:309-16 pubmed publisher
    ..Collectively, our data reveal the molecular basis of H2A.Z-specific recognition by YL1 and shed light on the mechanism of H2A.Z transfer to the nucleosome by the ATP-dependent chromatin-remodeling complexes SRCAP and P400-TIP60. ..
  64. Helali M, Addeo P, Heimburger C, Detour J, Goichot B, Bachellier P, et al. Carbidopa-assisted 18F-fluorodihydroxyphenylalanine PET/CT for the localization and staging of non-functioning neuroendocrine pancreatic tumors. Ann Nucl Med. 2016;30:659-668 pubmed
    ..Contrary to widely held assumptions, our study further expands the application of CD-assisted 18F-FDOPA PET/CT for non-functioning pNETs when 68Ga-radiolabeled somatostatin analogs are not available. ..
  65. Derhy D, Sauer A, Sabou M, Letsch J, Candolfi E, Letscher Bru V, et al. Surgical treatment of Metarhizium anisopliae sclerokeratitis and endophthalmitis. Indian J Ophthalmol. 2017;65:523-526 pubmed publisher
    ..Functional outcome remained very poor. This is the first case of sclerokeratitis and endophthalmitis caused by MA ever reported. The infection was successfully treated with an aggressive combination of medical and surgical treatments. ..
  66. Mackay A, Burford A, Carvalho D, Izquierdo E, Fazal Salom J, Taylor K, et al. Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. Cancer Cell. 2017;32:520-537.e5 pubmed publisher
  67. Li X, Mantovani R, Hooft van Huijsduijnen R, Andre I, Benoist C, Mathis D. Evolutionary variation of the CCAAT-binding transcription factor NF-Y. Nucleic Acids Res. 1992;20:1087-91 pubmed
  68. Kintz P, Cirimele V, Edel Y, Tracqui A, Mangin P. Characterization of dextromoramide (Palfium) abuse by hair analysis in a denied case. Int J Legal Med. 1995;107:269-72 pubmed
    ..5 cm, corresponding to a growth period of 2 months. Concentrations were 1.09, 1.93 and 1.48 ng/mg from the root to the end, respectively. This is the first report on dextromoramide testing in human hair. ..
  69. Duclos F, Rodius F, Wrogemann K, Mandel J, Koenig M. The Friedreich ataxia region: characterization of two novel genes and reduction of the critical region to 300 kb. Hum Mol Genet. 1994;3:909-14 pubmed
    ..The lack of causative mutations in the three genes and the position of the recombination further delineate the FRDA locus to a 300 kb interval. ..
  70. Husselstein T, Schaller H, Gachotte D, Benveniste P. Delta7-sterol-C5-desaturase: molecular characterization and functional expression of wild-type and mutant alleles. Plant Mol Biol. 1999;39:891-906 pubmed
    ..The occurrence of a hydroxylated amino acid (Thr or Ser) at the position corresponding to Thr-114 in the five delta7-sterol-C5(6)-desaturases identified so far suggests that this amino acid is important for normal enzymatic function...
  71. Marin H, Vargas M, Grebici Guessoum M, Lenz V, Klein N, Bin J, et al. [Epidermoid cyst of the fourth ventricle: four case reports]. J Neuroradiol. 2002;29:146-52 pubmed
    ..DWI images are useful for postsurgical evaluation of residual tumor. Extension of the cyst into the CP angle cisterns usually precludes complete surgical resection. ..
  72. Flori E, Biancalana V, Girard Lemaire F, Favre R, Flori J, Doray B, et al. Difficulties of genetic counseling and prenatal diagnosis in a consanguineous couple segregating for the same translocation (14;15) (q11;q13) and at risk for Prader-Willi and Angelman syndromes. Eur J Hum Genet. 2004;12:181-6 pubmed
  73. Mansour Z, Kochetkova E, Ducrocq X, Vasilescu M, Maxant G, Buggenhout A, et al. Induction chemotherapy does not increase the operative risk of pneumonectomy!. Eur J Cardiothorac Surg. 2007;31:181-5 pubmed
    ..3% in group 1 and 3.4% in group 2 (p=0.675). In opposition to previous reports, induction chemotherapy did not significantly jeopardize post-operative outcome following pneumonectomy in our experience. ..
  74. Roth S, Raul J, Willinger R. Biofidelic child head FE model to simulate real world trauma. Comput Methods Programs Biomed. 2008;90:262-74 pubmed publisher
    ..These analysis point out significant differences showing that scaling down an adult head to obtain a child head does not appear relevant. Biofidelic and specific child geometry is needed to investigate child injury mechanisms. ..
  75. Battistella M, Fraitag S, Cribier B. A unique presentation of eccrine hamartoma: eccrine nevus with abnormal eccrine structures and angiomyxoid stroma. Am J Dermatopathol. 2009;31:682-4 pubmed publisher
    ..This angiomyxoid stroma was somewhat reminiscent of mucinous eccrine nevi and eccrine angiomatous hamartomas. We propose to describe this unique lesion inside the group of eccrine nevi with the term "angiomyxoid eccrine nevus."..
  76. Tavian M, Biasch K, Sinka L, Vallet J, Peault B. Embryonic origin of human hematopoiesis. Int J Dev Biol. 2010;54:1061-5 pubmed publisher
    ..The recent discovery that angiotensin-converting enzyme (ACE) is a novel cell surface marker of human HSC is discussed in detail. ..
  77. Marion V, Schlicht D, Mockel A, Caillard S, Imhoff O, Stoetzel C, et al. Bardet-Biedl syndrome highlights the major role of the primary cilium in efficient water reabsorption. Kidney Int. 2011;79:1013-25 pubmed publisher
    ..These findings suggest that the luminal receptor located on the primary cilium may be important for efficient transepithelial water absorption. ..
  78. van Laar J, Farge D, Sont J, Naraghi K, Marjanovic Z, Larghero J, et al. Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial. JAMA. 2014;311:2490-8 pubmed publisher
    ..However, HCST conferred a significant long-term event-free survival benefit. Identifier: ISRCTN54371254. ..
  79. Mazieres J, Barlesi F, Filleron T, Besse B, Monnet I, Beau Faller M, et al. Lung cancer patients with HER2 mutations treated with chemotherapy and HER2-targeted drugs: results from the European EUHER2 cohort. Ann Oncol. 2016;27:281-6 pubmed publisher
    ..This series shows the chemosensitivity of HER2-driven NSCLC, and the potential interest of HER2-targeted agents. Our results should help to define the best therapeutic strategy for these patients and to orient future clinical trials. ..
  80. Kantarjian H, Lioure B, Kim S, Atallah E, Leguay T, Kelly K, et al. A Phase II Study of Coltuximab Ravtansine (SAR3419) Monotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia. Clin Lymphoma Myeloma Leuk. 2016;16:139-45 pubmed publisher
    ..9 months (range, 1-5.6 months). Because of these results, the study was prematurely discontinued. Coltuximab ravtansine was well tolerated but was associated with a low clinical response rate in patients with relapsed or refractory ALL. ..
  81. Addeo P, Cesaretti M, Fuchshuber P, Langella S, Simoné G, Oussoultzoglou E, et al. Outcomes of liver resection for haemorrhagic hepatocellular adenoma. Int J Surg. 2016;27:34-8 pubmed publisher
    ..03). In all the resected H-HCAs, pathology showed central haemorrhagic changes with tumoral cells at the periphery of the lesions. Liver resection for H- and NH-HCAs can be achieved with no mortality and comparable short-term outcomes. ..
  82. Lucereau B, Thaveau F, Lejay A, Roussin M, Georg Y, Heim F, et al. Learning Curve of Robotic-Assisted Anastomosis: Shorter than the Laparoscopic Technique? An Educational Study. Ann Vasc Surg. 2016;33:39-44 pubmed publisher
    ..The robotic-assisted technique tended to improve suturing skills and should be considered as a valuable tool to reduce the technical learning curve. ..
  83. Berna F, Blanc F, Lebrun C, Castelnovo G, Clerc C, Debouverie M, et al. Should a psychotic or manic episode be considered an early manifestation of Multiple Sclerosis? A multiple case study. Mult Scler Relat Disord. 2016;6:93-6 pubmed publisher
    ..Based on this multiple case study, we question whether past psychotic or manic episode should be considered equivalent to a first manifestation of MS. ..
  84. Claudet I, Mouvier S, Labadie M, Manin C, Michard Lenoir A, Eyer D, et al. Unintentional Cannabis Intoxication in Toddlers. Pediatrics. 2017;140: pubmed publisher
    ..Intoxicated children are more frequent, are younger, and have intoxications that are more severe. This raises a real issue of public health. ..
  85. Mosser J, Lutz Y, Stoeckel M, Sarde C, Kretz C, Douar A, et al. The gene responsible for adrenoleukodystrophy encodes a peroxisomal membrane protein. Hum Mol Genet. 1994;3:265-71 pubmed
    ..Distinct immunofluorescence patterns were observed in cell lines from patients with Zellweger syndrome (a peroxisomal biogenesis disorder) belonging to different complementation groups...
  86. Robert I, Quirin Stricker C. A novel untranslated 'exon H' of the human choline acetyltransferase gene in placenta. J Neurochem. 2001;79:9-16 pubmed
    ..These data may be possibly explained by the presence of a placenta specific promoter in the ChAT gene, which might be the proximal promoter P1. ..
  87. Poinat P, De Arcangelis A, Sookhareea S, Zhu X, Hedgecock E, Labouesse M, et al. A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans. Curr Biol. 2002;12:622-31 pubmed
    ..Using several models, we provide the first evidence that the kinase NIK and integrins interact in vitro and in vivo. This interaction is required for proper axonal navigation in C. elegans. ..
  88. Goumon Y, Muller A, Glattard E, Marban C, Gasnier C, Strub J, et al. Identification of morphine-6-glucuronide in chromaffin cell secretory granules. J Biol Chem. 2006;281:8082-9 pubmed
    ..Taken together, our data represent an important observation on the role of morphine-6-glucuronide as a new endocrine factor. ..
  89. Arntz Y, Jourdainne L, Greiner Wacker G, Rinckenbach S, Ogier J, Voegel J, et al. Immunogold detection of types I and II chondrocyte collagen fibrils: an in situ atomic force microscopic investigation. Microsc Res Tech. 2006;69:283-90 pubmed
    ..This simple approach could be of major interest for the biologist community in routine laboratory investigations, to localize in situ, macromolecules of the extracellular matrix. ..
  90. Gomes Ferreira C, Reinberg O, Becmeur F, Allal H, De Lagausie P, Lardy H, et al. Neonatal minimally invasive surgery for congenital diaphragmatic hernias: a multicenter study using thoracoscopy or laparoscopy. Surg Endosc. 2009;23:1650-9 pubmed publisher
    ..Reduction of the herniated organs is easier using thoracoscopy. Right CDH, liver lobe herniation, and the need for a patch closure are the most frequent reasons for conversion. ..
  91. Maldonado Celis M, Bousserouel S, Gosse F, Lobstein A, Raul F. Apple procyanidins activate apoptotic signaling pathway in human colon adenocarcinoma cells by a lipid-raft independent mechanism. Biochem Biophys Res Commun. 2009;388:372-6 pubmed publisher
    ..These results highlight the potential of Pcy as a direct activator of TRAIL-death receptors in cell membrane even in the absence of lipid rafts. ..
  92. Lesot H, Clauss F, Maniere M, Schmittbuhl M. Consequences of X-linked hypohidrotic ectodermal dysplasia for the human jaw bone. Front Oral Biol. 2009;13:93-9 pubmed publisher
    ..If the changes in jaw bone morphology can be a consequence of oligodontia, the changes in bone structure seem to be tooth-independent and suggest a direct effect of the mutation on bone formation and/or remodeling. ..