Experts and Doctors on animals in Strasbourg, Alsace Champagne Ardenne Lorraine, France

Summary

Locale: Strasbourg, Alsace Champagne Ardenne Lorraine, France
Topic: animals

Top Publications

  1. Nagpal S, Zelent A, Chambon P. RAR-beta 4, a retinoic acid receptor isoform is generated from RAR-beta 2 by alternative splicing and usage of a CUG initiator codon. Proc Natl Acad Sci U S A. 1992;89:2718-22 pubmed
    ..RAR-beta 4 exhibits a tissue-specific pattern of expression and distinct transcriptional activation properties when compared with the other RAR-beta isoforms. ..
  2. Stoetzel C, Weber B, Bourgeois P, Bolcato Bellemin A, Perrin Schmitt F. Dorso-ventral and rostro-caudal sequential expression of M-twist in the postimplantation murine embryo. Mech Dev. 1995;51:251-63 pubmed
    ..In addition, we show the existence of some previously undescribed subsets of scattered cells that express M-twist and thus might participate in murine embryo development. ..
  3. Ruel L, Pantesco V, Lutz Y, Simpson P, Bourouis M. Functional significance of a family of protein kinases encoded at the shaggy locus in Drosophila. EMBO J. 1993;12:1657-69 pubmed
    ..This protein probably also functions as part of a signal transduction cascade in the imaginal neuroepithelium, where cells have to choose between epidermal and neural fates. ..
  4. Baltzinger M, Relaix F, Remy P. Transcription of XLPOU3, a brain-specific gene, during Xenopus laevis early embryogenesis. Mech Dev. 1996;58:103-14 pubmed
    ..In addition, XLPOU3 transcription is observed in a restricted region of the auditory vesicle during development. The results suggest that XLPOU3 may participate in patterning the central nervous system during early Xenopus development. ..
  5. Teclemariam Mesbah R, Kalsbeek A, Buijs R, Pevet P. Oxytocin innervation of spinal preganglionic neurons projecting to the superior cervical ganglion in the rat. Cell Tissue Res. 1997;287:481-6 pubmed
    ..The implications of these observations for the overall timing message received by the spinal preganglionic neurons are discussed. ..
  6. Fimia G, De Cesare D, Sassone Corsi P. CBP-independent activation of CREM and CREB by the LIM-only protein ACT. Nature. 1999;398:165-9 pubmed
    ..ACT may define a previously undiscovered class of tissue-specific coactivators whose function could be specific for distinct cellular differentiation programmes. ..
  7. Fajas L, Landsberg R, Huss Garcia Y, Sardet C, Lees J, Auwerx J. E2Fs regulate adipocyte differentiation. Dev Cell. 2002;3:39-49 pubmed
    ..This underscores the complex role of the E2F protein family in the control of both cell proliferation and differentiation. ..
  8. Boudard D, Mendoza J, Hicks D. Loss of photic entrainment at low illuminances in rats with acute photoreceptor degeneration. Eur J Neurosci. 2009;30:1527-36 pubmed publisher
    ..Our study provides a comprehensive model of photoreceptor degeneration at the adult stage and a simple and versatile method to investigate the relation between retinal photoreceptors and the circadian system. ..
  9. Charles A, Guilbert A, Bouitbir J, Goette Di Marco P, Enache I, Zoll J, et al. Effect of postconditioning on mitochondrial dysfunction in experimental aortic cross-clamping. Br J Surg. 2011;98:511-6 pubmed publisher
    ..Mitochondrial protection to reduce reperfusion injury in clinical vascular surgery may be warranted. ..

More Information

Publications470 found, 100 shown here

  1. Saadi Thiers K, Huck O, Simonis P, Tilly P, Fabre J, Tenenbaum H, et al. Periodontal and systemic responses in various mice models of experimental periodontitis: respective roles of inflammation duration and Porphyromonas gingivalis infection. J Periodontol. 2013;84:396-406 pubmed publisher
    ..This study compared the effect of Porphyromonas gingivalis (Pg) infection and experimental periodontitis duration at local and systemic levels in various models...
  2. Saubusse T, Masson J, Le Dimma M, Abrial D, Marcé C, Martin Schaller R, et al. How to survey classical swine fever in wild boar (Sus scrofa) after the completion of oral vaccination? Chasing away the ghost of infection at different spatial scales. Vet Res. 2016;47:21 pubmed publisher
    ..We recommend using quantitative serological tools, hunting data modelling and capture approaches for better interpreting serological results after vaccination completion. Surveillance perspectives are further discussed. ..
  3. Guy B, Geist M, Dott K, Spehner D, Kieny M, Lecocq J. A specific inhibitor of cysteine proteases impairs a Vif-dependent modification of human immunodeficiency virus type 1 Env protein. J Virol. 1991;65:1325-31 pubmed
    ..These observations suggest that a cysteine protease activity is associated with Vif and that this activity plays a role in Env maturation. ..
  4. Nicolas E, Nappi A, Lemaitre B. Expression of antimicrobial peptide genes after infection by parasitoid wasps in Drosophila. Dev Comp Immunol. 1996;20:175-81 pubmed
    ..As the parasitoids elicit a cellular response, our data suggest that the antimicrobial responses are activated and/or regulated by mechanisms that are independent of those mediating cellular encapsulation. ..
  5. Masson R, Lefebvre O, Noel A, Fahime M, Chenard M, Wendling C, et al. In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy. J Cell Biol. 1998;140:1535-41 pubmed
    ..Therefore, ST3 represents an appropriate target for specific MMP inhibitor(s) in future therapeutical approaches directed against the stromal compartment of human carcinomas. ..
  6. Tabopda T, Liu J, Ngadjui B, Luu B. Cytotoxic triterpene and sesquiterpene lactones from Elephantopus mollis and induction of apoptosis in neuroblastoma cells. Planta Med. 2007;73:376-80 pubmed
    ..No significant difference was observed for cytotoxicity of compound 5 towards all 3 cell lines tested. ..
  7. Lamy V, Roussi S, Chaabi M, Gosse F, Schall N, Lobstein A, et al. Chemopreventive effects of lupulone, a hop {beta}-acid, on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis. Carcinogenesis. 2007;28:1575-81 pubmed
    ..These observations suggest the use of lupulones for colon cancer chemoprevention trials. ..
  8. Agez L, Laurent V, Guerrero H, Pevet P, Masson Pévet M, Gauer F. Endogenous melatonin provides an effective circadian message to both the suprachiasmatic nuclei and the pars tuberalis of the rat. J Pineal Res. 2009;46:95-105 pubmed publisher
    ..These results show that NOR can be regulated by the melatonin circadian rhythm in the PT and could be the link between the physiological action of melatonin and the core of the molecular circadian clock in this tissue. ..
  9. Arnold J, Murera D, Arbogast F, Fauny J, Muller S, Gros F. Autophagy is dispensable for B-cell development but essential for humoral autoimmune responses. Cell Death Differ. 2016;23:853-64 pubmed publisher
    ..Thus, treatments specifically targeting autophagy might be beneficial in systemic autoimmune diseases. ..
  10. Brand N, Petkovich M, Chambon P. Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-alpha). Nucleic Acids Res. 1990;18:6799-806 pubmed
  11. de Murcia G, Menissier de Murcia J. Poly(ADP-ribose) polymerase: a molecular nick-sensor. Trends Biochem Sci. 1994;19:172-6 pubmed
    ..Cloning of the PARP gene has allowed the development of genetic and molecular approaches to elucidate the structure and function of this abundant and highly conserved enzyme. ..
  12. de Groot R, Auwerx J, Bourouis M, Sassone Corsi P. Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy. Oncogene. 1993;8:841-7 pubmed
    ..Here we show that the products of the sgg gene can also function as negative regulators of Jun/AP-1. ..
  13. Dimarcq J, Imler J, Lanot R, Ezekowitz R, Hoffmann J, Janeway C, et al. Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression. Insect Biochem Mol Biol. 1997;27:877-86 pubmed
    ..We also report that expression of several regulatory molecules thought to be involved in the immune response is up-regulated by ecdysone in l(2)mbn cells. ..
  14. Paul S, Snary D, Hoebeke J, Allen D, Balloul J, Bizouarne N, et al. Targeted macrophage cytotoxicity using a nonreplicative live vector expressing a tumor-specific single-chain variable region fragment. Hum Gene Ther. 2000;11:1417-28 pubmed
    ..Furthermore, activated macrophages expressing the membrane-bound scFv specifically lyse target cells expressing the MUC1 antigen but not cells that do not express MUC1. ..
  15. Bolanos Jimenez F, Bordais A, Behra M, Strahle U, Sahel J, Rendon A. Dystrophin and Dp71, two products of the DMD gene, show a different pattern of expression during embryonic development in zebrafish. Mech Dev. 2001;102:239-41 pubmed
    ..The complementary patterns of expression of dystrophin and Dp71 suggest that these two proteins exert different functions during embryonic development in zebrafish. ..
  16. Challet E, Pitrosky B, Sicard B, Malan A, Pevet P. Circadian organization in a diurnal rodent, Arvicanthis ansorgei Thomas 1910: chronotypes, responses to constant lighting conditions, and photoperiodic changes. J Biol Rhythms. 2002;17:52-64 pubmed
    ..The data indicate that A. ansorgei is an interesting experimental model to understand the regulation of the circadian timing system in day-active species. ..
  17. Angenieux C, Salamero J, Fricker D, Wurtz J, Maitre B, Cazenave J, et al. Common characteristics of the human and rhesus macaque CD1e molecules: conservation of biochemical and biological properties during primate evolution. Immunogenetics. 2003;54:842-9 pubmed
  18. Garwood J, Heck N, Reichardt F, Faissner A. Phosphacan short isoform, a novel non-proteoglycan variant of phosphacan/receptor protein tyrosine phosphatase-beta, interacts with neuronal receptors and promotes neurite outgrowth. J Biol Chem. 2003;278:24164-73 pubmed
    ..Hence, the identification of this novel isoform of phosphacan/receptor protein tyrosine phosphatase-beta provides a new component in cell-cell and cell-extracellular matrix signaling events in which these proteins have been implicated. ..
  19. Coowar D, Bouissac J, Hanbali M, Paschaki M, Mohier E, Luu B. Effects of indole fatty alcohols on the differentiation of neural stem cell derived neurospheres. J Med Chem. 2004;47:6270-82 pubmed
    ..Analysis of the expression of the Notch pathway genes in neurospheres treated during the differentiation phase with 13c (n = 18) revealed a significant decrease in the transcription of the Notch 4 receptor...
  20. Stoetzel C, Muller J, Laurier V, Davis E, Zaghloul N, Vicaire S, et al. Identification of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome. Am J Hum Genet. 2007;80:1-11 pubmed
  21. Momboisse F, Ory S, Calco V, Malacombe M, Bader M, Gasman S. Calcium-regulated exocytosis in neuroendocrine cells: intersectin-1L stimulates actin polymerization and exocytosis by activating Cdc42. Ann N Y Acad Sci. 2009;1152:209-14 pubmed publisher
    ..Here, we propose that the neuronal guanine nucleotide exchange factor, intersectin-1L, activates the GTPase Cdc42, which in turn provides de novo actin filaments that are important for calcium-regulated exocytosis in PC12 cells. ..
  22. Minoux M, Antonarakis G, Kmita M, Duboule D, Rijli F. Rostral and caudal pharyngeal arches share a common neural crest ground pattern. Development. 2009;136:637-45 pubmed publisher
    ..These results provide insights into how facial and throat structures are assembled during development, and have implications for the evolution of the pharyngeal region of the vertebrate head. ..
  23. Saleh M, Jehl F, Dory A, Lefevre S, Prevost G, Gaucher D, et al. Ocular penetration of topically applied linezolid in a rabbit model. J Cataract Refract Surg. 2010;36:488-92 pubmed publisher
    ..Linezolid could be a valuable alternative in cases of increased resistance to vancomycin. ..
  24. Bessot J, Metz Favre C, Rame J, de Blay F, Pauli G. Tropomyosin or not tropomyosin, what is the relevant allergen in house dust mite and snail cross allergies?. Eur Ann Allergy Clin Immunol. 2010;42:3-10 pubmed
    ..The effects of HDM immunotherapy in snail allergy are questioned. Knowledge of taxonomy can contribute to more precise evaluation of cross reactivities between crustaceans and molluscs. ..
  25. Bai P, Canto C, Oudart H, Brunyánszki A, Cen Y, Thomas C, et al. PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation. Cell Metab. 2011;13:461-468 pubmed publisher
    ..These data show how PARP-1 inhibition has strong metabolic implications through the modulation of SIRT1 activity, a property that could be useful in the management not only of metabolic diseases, but also of cancer. ..
  26. Fafi Kremer S, Fauvelle C, Felmlee D, Zeisel M, Lepiller Q, Fofana I, et al. Neutralizing antibodies and pathogenesis of hepatitis C virus infection. Viruses. 2012;4:2016-30 pubmed publisher
    ..This review summarizes recent concepts of the role of neutralizing antibodies in viral clearance and protection, and highlights consequences of viral escape from neutralizing antibodies in the pathogenesis of HCV infection. ..
  27. Lutz P, Kieffer B. Opioid receptors: distinct roles in mood disorders. Trends Neurosci. 2013;36:195-206 pubmed publisher
  28. Girardi E, Chane Woon Ming B, Messmer M, Kaukinen P, Pfeffer S. Identification of RNase L-dependent, 3'-end-modified, viral small RNAs in Sindbis virus-infected mammalian cells. MBio. 2013;4:e00698-13 pubmed publisher
    ..Altogether, our findings indicate that in our system RNA silencing is not active against Sindbis virus (SINV) and might open the way to a better understanding of the antiviral response mediated by a novel class of small RNAs. ..
  29. Schwitzer T, Schwan R, Angioi Duprez K, Giersch A, Laprévote V. The Endocannabinoid System in the Retina: From Physiology to Practical and Therapeutic Applications. Neural Plast. 2016;2016:2916732 pubmed publisher
    ..Finally, we argue for the relevance of functional retinal measures in cannabis users to evaluate the impact of cannabis use on human retinal processing. ..
  30. Maitre M. [Memory and synaptic plasticity]. Ann Biol Clin (Paris). 1996;54:49-66 pubmed
    ..The building of new synaptic contacts and/or the plastic evolution of existing synapses could explain long-term LTP and long-term memory traces. ..
  31. Strub J, Goumon Y, Lugardon K, Capon C, Lopez M, Moniatte M, et al. Antibacterial activity of glycosylated and phosphorylated chromogranin A-derived peptide 173-194 from bovine adrenal medullary chromaffin granules. J Biol Chem. 1996;271:28533-40 pubmed
  32. Leroy C, Poisbeau P, Keller A, Nehlig A. Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy. J Physiol. 2004;557:473-87 pubmed
    ..The failure of benzodiazepine and neurosteroid to potentiate inhibition early after SE may be a critical factor in the development of epileptogenesis and occurrence of seizures. ..
  33. Dufour V, Pascalis O, Petit O. Face processing limitation to own species in primates: a comparative study in brown capuchins, Tonkean macaques and humans. Behav Processes. 2006;73:107-13 pubmed
    ..This work suggests in all species tested the existence of a common trait inherited from the primate ancestor: an efficient system to identify individual faces of own species only. ..
  34. Calon A, Gross I, Lhermitte B, Martin E, Beck F, Duclos B, et al. Different effects of the Cdx1 and Cdx2 homeobox genes in a murine model of intestinal inflammation. Gut. 2007;56:1688-95 pubmed
    ..This is mirrored by different functional interactions of the CDX1 and CDX2 proteins with SMAD3, a major element of the TGFbeta signalling pathway. ..
  35. Paul S, Geist M, Dott K, Snary D, Taylor Papadimitriou J, Acres B, et al. Specific tumor cell targeting by a recombinant MVA expressing a functional single chain antibody on the surface of intracellular mature virus (IMV) particles. Viral Immunol. 2007;20:664-71 pubmed
    ..The construct containing the antibody was able to bind a MUC-1 specific 60mer peptide. Moreover, targeted virus infects MUC-1-expressing cells in vitro more efficiently. ..
  36. Gobert A, Gutmann B, Taschner A, Gossringer M, Holzmann J, Hartmann R, et al. A single Arabidopsis organellar protein has RNase P activity. Nat Struct Mol Biol. 2010;17:740-4 pubmed publisher
    ..Finally, we show that Arabidopsis PRORP1 can replace the bacterial ribonucleoprotein RNase P in Escherichia coli cells. PRORP2 and PRORP3, two paralogs of PRORP1, are both localized in the nucleus. ..
  37. Bobu C, Sandu C, Laurent V, Felder Schmittbuhl M, Hicks D. Prolonged light exposure induces widespread phase shifting in the circadian clock and visual pigment gene expression of the Arvicanthis ansorgei retina. Mol Vis. 2013;19:1060-73 pubmed
  38. Pasquaretta C, Battesti M, Klenschi E, Bousquet C, Sueur C, Mery F. How social network structure affects decision-making in Drosophila melanogaster. Proc Biol Sci. 2016;283:20152954 pubmed publisher
    ..In particular, we found that the variance of individual centrality parameters among informed flies was lower in the case of a 'follow' outcome compared with the case of an 'avoid' outcome. ..
  39. Mendoza Viveros L, Chiang C, Ong J, Hegazi S, Cheng A, Bouchard Cannon P, et al. miR-132/212 Modulates Seasonal Adaptation and Dendritic Morphology of the Central Circadian Clock. Cell Rep. 2017;19:505-520 pubmed publisher
    ..Our results reveal that, by regulating the dendritic structure of SCN neurons through a MeCP2-dependent mechanism, miR-132/212 affects the capacity of the SCN to encode seasonal time. ..
  40. Genschik P, Philipps G, Gigot C, Fleck J. Cloning and sequence analysis of a cDNA clone from Arabidopsis thaliana homologous to a proteasome alpha subunit from Drosophila. FEBS Lett. 1992;309:311-5 pubmed
    ..This subunit might share important functions in both kingdoms, as revealed by the important conservation between plants and animals. In plant cells it is encoded by a single-copy gene and probably regulated by stress and/of division. ..
  41. Baltzinger M, Payen E, Remy P. Nucleotide sequence of XLPOU3 cDNA, a member of the POU domain gene family expressed in Xenopus laevis embryos. Nucleic Acids Res. 1992;20:1993 pubmed
  42. Matthes H, Boschert U, Amlaiky N, Grailhe R, Plassat J, Muscatelli F, et al. Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Mol Pharmacol. 1993;43:313-9 pubmed
  43. Baltzinger M, Mager Heckel A, Remy P. Xl erg: expression pattern and overexpression during development plead for a role in endothelial cell differentiation. Dev Dyn. 1999;216:420-33 pubmed
    ..In both cases, accumulation of erythrocytes in structures not connected with the blood circulatory system can be observed. Our data suggest that Xl erg may be involved in cell motility and in the development of the circulatory system. ..
  44. Lagueux M, Perrodou E, Levashina E, Capovilla M, Hoffmann J. Constitutive expression of a complement-like protein in toll and JAK gain-of-function mutants of Drosophila. Proc Natl Acad Sci U S A. 2000;97:11427-32 pubmed
    ..We also observe a constitutive expression in gain-of-function Toll mutants. We discuss the possible roles of these novel complement-like proteins in the Drosophila host defense. ..
  45. Vermot J, Gallego Llamas J, Fraulob V, Niederreither K, Chambon P, Dolle P. Retinoic acid controls the bilateral symmetry of somite formation in the mouse embryo. Science. 2005;308:563-6 pubmed
    ..These data implicate retinoic acid as an endogenous signal that maintains the bilateral synchrony of mesoderm segmentation, and therefore controls bilateral symmetry, in vertebrate embryos. ..
  46. Fofana I, Krieger S, Grunert F, Glauben S, Xiao F, Fafi Kremer S, et al. Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes. Gastroenterology. 2010;139:953-64, 964.e1-4 pubmed publisher
    ..Monoclonal antibodies against the HCV entry factor CLDN1 might be used to prevent HCV infection, such as after liver transplantation, and might also restrain virus spread in chronically infected patients. ..
  47. Maillé A, Roeder J. Inferences about the location of food in lemurs (Eulemur macaco and Eulemur fulvus): a comparison with apes and monkeys. Anim Cogn. 2012;15:1075-83 pubmed publisher
    ..The results are compared with the performances recorded in apes and monkeys under the same paradigm. ..
  48. Vernay A, Sellal F, Rene F. Evaluating Behavior in Mouse Models of the Behavioral Variant of Frontotemporal Dementia: Which Test for Which Symptom?. Neurodegener Dis. 2016;16:127-39 pubmed publisher
  49. Chypre M, Seaman J, Cordeiro O, Willen L, Knoop K, Buchanan A, et al. Characterization and application of two RANK-specific antibodies with different biological activities. Immunol Lett. 2016;171:5-14 pubmed publisher
    ..This characterization of two monoclonal antibodies should now allow better evaluation of their application as therapeutic reagents and investigative tools. ..
  50. Smith W, Nakshatri H, Leroy P, Rees J, Chambon P. A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter. EMBO J. 1991;10:2223-30 pubmed
    ..The control of CRBPI gene transcription by RA-RAR complexes interacting with the RARE characterized here may correspond to a feedback mechanism important in regulating retinoid metabolism and action. ..
  51. Aunis D, Bader M. The cytoskeleton as a barrier to exocytosis in secretory cells. J Exp Biol. 1988;139:253-66 pubmed
    ..This dissolution of cytoskeletal filaments should result in granule detachment and permit granules free access to exocytotic sites on the plasma membrane. ..
  52. Masquilier D, Foulkes N, Mattei M, Sassone Corsi P. Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript. Cell Growth Differ. 1993;4:931-7 pubmed
    ..Finally, we show the conservation of CREM cyclic AMP transcriptional inducibility in humans and establish that the induced transcripts correspond to the mouse ICER products. ..
  53. Imbert G, Trottier Y, Beckmann J, Mandel J. The gene for the TATA binding protein (TBP) that contains a highly polymorphic protein coding CAG repeat maps to 6q27. Genomics. 1994;21:667-8 pubmed
  54. Huet F, Ruiz C, Richards G. Puffs and PCR: the in vivo dynamics of early gene expression during ecdysone responses in Drosophila. Development. 1993;118:613-27 pubmed
    ..As these molecules have homologues in vertebrates, our analysis may have general implications for the organisation of hormonal responses in vivo. ..
  55. Fausser J, Ungewickell E, Ruch J, Lesot H. Interaction of vinculin with the clathrin heavy chain. J Biochem. 1993;114:498-503 pubmed
    ..Presence of clathrin light chain (CLC) associated with the CHC did not affect its interaction with vinculin. Vinculin did not interact with the CLC. ..
  56. Kieffer Combeau S, Meyer J, Lesot H. Cell-matrix interactions and cell-cell junctions during epithelial histo-morphogenesis in the developing mouse incisor. Int J Dev Biol. 2001;45:733-42 pubmed
    ..Apoptosis was transiently observed in the contiguous mesenchyme. This affected osteoblasts and also nerve cells close to the labial part of the cervical loop. ..
  57. Poirel V, Cailotto C, Streicher D, Pevet P, Masson Pévet M, Gauer F. MT1 melatonin receptor mRNA tissular localization by PCR amplification. Neuro Endocrinol Lett. 2003;24:33-8 pubmed
    ..Our present data strengthen the idea that the nocturnally restricted melatonin secretion could be one internal zeitgeber that putatively distributes the endogenous circadian rhythmicity to all tissues expressing melatonin receptors. ..
  58. Raveloson H, Le Minor J, Rumpler Y, Schmittbuhl M. Shape of the lateral mandibular outline in Lemuridae: a quantitative analysis of variability using elliptical Fourier analysis. Folia Primatol (Basel). 2005;76:245-61 pubmed
    ..The patterns of intergeneric and intrageneric shape variations of the mandible in Lemuridae presented here provide a valuable resource for the analysis of variation among living and fossil lemurids. ..
  59. Pevet P, Agez L, Bothorel B, Saboureau M, Gauer F, Laurent V, et al. Melatonin in the multi-oscillatory mammalian circadian world. Chronobiol Int. 2006;23:39-51 pubmed
    ..The molecular mechanisms underlying this chronobiotic effect have also been investigated in rats. REV-ERB alpha seems to be the initial molecular target. ..
  60. Cassel J, Lazaris A, Birthelmer A, Jackisch R. Spatial reference- (not working- or procedural-) memory performance of aged rats in the water maze predicts the magnitude of sulpiride-induced facilitation of acetylcholine release by striatal slices. Neurobiol Aging. 2007;28:1270-85 pubmed
  61. Rejiba S, Wack S, Aprahamian M, Hajri A. K-ras oncogene silencing strategy reduces tumor growth and enhances gemcitabine chemotherapy efficacy for pancreatic cancer treatment. Cancer Sci. 2007;98:1128-36 pubmed
    ..The improvement of gemcitabine-based chemotherapy suggests that this strategy might be used therapeutically against human pancreatic cancer to potentiate the effects of conventional therapy. ..
  62. Gérard M, Krol A, Carbon P. Transcription factor hStaf/ZNF143 is required for expression of the human TFAM gene. Gene. 2007;401:145-53 pubmed
    ..Altogether, our data led to the conclusion that the promoter of the human TFAM gene harbors a complex organization with at least six transcriptional regulatory elements. ..
  63. Maitre B, Angenieux C, Salamero J, Hanau D, Fricker D, Signorino F, et al. Control of the intracellular pathway of CD1e. Traffic. 2008;9:431-45 pubmed publisher
    ..This ubiquitin-dependent pathway may explain several features of the very particular intracellular traffic of CD1e in dendritic cells compared with other CD1 molecules. ..
  64. Pain L, Oberling P, Mainsongeon M, Moulinoux J, Simonnet G. Delayed aversive effects of high-dose fentanyl. Prevention by a polyamine-deficient diet. Behav Brain Res. 2008;190:119-23 pubmed publisher
    ..The 24-h delayed aversive effects of fentanyl were not observed in animals submitted to a polyamine-deficient diet, suggesting an NMDA-dependent mechanism. ..
  65. Francois J, Ferrandon A, Koning E, Angst M, Sandner G, Nehlig A. Selective reorganization of GABAergic transmission in neonatal ventral hippocampal-lesioned rats. Int J Neuropsychopharmacol. 2009;12:1097-110 pubmed publisher
  66. Betton D, Greib N, Schlotterbeck H, Joshi G, Ubeaud Sequier G, Diemunsch P. The pharmacokinetics of ropivacaine after intraperitoneal administration: instillation versus nebulization. Anesth Analg. 2010;111:1140-5 pubmed publisher
    ..The free fraction of ropivacaine was also similar in the 2 groups. The pharmacokinetic profile of ropivacaine nebulization is similar to direct intraperitoneal instillation, but with a lower absorption rate. ..
  67. Bourjade M, Thierry B, Call J, Dufour V. Are monkeys able to plan for future exchange?. Anim Cogn. 2012;15:783-95 pubmed publisher
    ..Instead, these results may reflect subjects' strengths and weaknesses in their time-related comprehension of the task...
  68. Compe E, Egly J. TFIIH: when transcription met DNA repair. Nat Rev Mol Cell Biol. 2012;13:343-54 pubmed publisher
    ..In this way, studies of TFIIH have revealed tight molecular connections between transcription and DNA repair and have helped to define the concept of 'transcription diseases'. ..
  69. Marois E, Scali C, Soichot J, Kappler C, Levashina E, Catteruccia F. High-throughput sorting of mosquito larvae for laboratory studies and for future vector control interventions. Malar J. 2012;11:302 pubmed publisher
    ..The developed method will greatly facilitate both laboratory studies of mosquito vectorial capacity requiring high-throughput approaches and future field interventions in the fight against infectious disease vectors. ..
  70. Gronemeyer H, Turcotte B, Quirin Stricker C, Bocquel M, Meyer M, Krozowski Z, et al. The chicken progesterone receptor: sequence, expression and functional analysis. EMBO J. 1987;6:3985-94 pubmed
    ..No stimulation of transcription can be detected when the C-terminal deletion extends into region C, indicating that this region is involved in the recognition of the hormone responsive element (HRE) of the MMTV LTR. ..
  71. Schuster C, Myslinski E, Krol A, Carbon P. Staf, a novel zinc finger protein that activates the RNA polymerase III promoter of the selenocysteine tRNA gene. EMBO J. 1995;14:3777-87 pubmed
    ..This constitutes the first demonstration of the capacity of a cloned factor to activate RNA polymerase III transcription in vivo. ..
  72. Katz J, Benoist C, Mathis D. Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice. Eur J Immunol. 1993;23:3358-60 pubmed
    ..We question this interpretation because NOD mice lacking MHC class I molecules, hence CD8+ T cells, do not display even insulitis when expected. ..
  73. Kolbe H, Huber A, Cordier P, Rasmussen U, Bouchon B, Jaquinod M, et al. Xenoxins, a family of peptides from dorsal gland secretion of Xenopus laevis related to snake venom cytotoxins and neurotoxins. J Biol Chem. 1993;268:16458-64 pubmed
    ..Potential functions of xenoxins as well as evolutionary aspects are discussed. ..
  74. Hoffmann J, Hetru C, Reichhart J. The humoral antibacterial response of Drosophila. FEBS Lett. 1993;325:63-6 pubmed
    ..We argue that the Drosophila host defense is homologous to the mammalian acute phase response. ..
  75. Matthes H, Maldonado R, Simonin F, Valverde O, Slowe S, Kitchen I, et al. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature. 1996;383:819-23 pubmed
    ..We conclude that the mu-opioid-receptor gene product is the molecular target of morphine in vivo and that it is a mandatory component of the opioid system for morphine action...
  76. Dumortier H, Klein Gunnewiek J, Roussel J, van Aarssen Y, Briand J, van Venrooij W, et al. At least three linear regions but not the zinc-finger domain of U1C protein are exposed at the surface of the protein in solution and on the human spliceosomal U1 snRNP particle. Nucleic Acids Res. 1998;26:5486-91 pubmed
    ..The N-terminal region of U1C, which is functional in U1 snRNP assembly, is apparently not located at the surface of the U1 snRNP particle. ..
  77. Servillo G, Della Fazia M, Sassone Corsi P. Transcription factor CREM coordinates the timing of hepatocyte proliferation in the regenerating liver. Genes Dev. 1998;12:3639-43 pubmed
    ..Expression of cyclins A, B, D1, E, and cdc2, of c-fos and tyrosine aminotransferase is deregulated. CREM mutation results in delayed S-phase entry, impairing the synchronization of proliferation. ..
  78. Williams G, Malin M, Vremec D, Chang C, Boyd R, Benoist C, et al. Mice lacking the transcription factor CIITA--a second look. Int Immunol. 1998;10:1957-67 pubmed
    ..Second, in contrast to recent results on human cell lines, CIITA is not critically involved in the IFN-gamma-induced up-regulation of MHC class I genes. ..
  79. Scrivener Y, Cribier B. [Morphology of sweat glands]. Morphologie. 2002;86:5-17 pubmed
    ..Sweat glands can be involved in various inflammatory processes and can lead to a large range of both benign and malignant tumors. ..
  80. Langley K, Hepp R, Grant N, Aunis D, Rodriguez Pena A. Thyroid hormones regulate adrenal chromaffin cell SNAP-25. Ann N Y Acad Sci. 2002;971:277-80 pubmed
  81. Abraham J, Himoudi N, Kien F, Berland J, Codran A, Bartosch B, et al. Comparative immunogenicity analysis of modified vaccinia Ankara vectors expressing native or modified forms of hepatitis C virus E1 and E2 glycoproteins. Vaccine. 2004;22:3917-28 pubmed
    ..Comparison of the three vectors shows an increase in the humoral response when antigens are secreted or membrane bound, and slightly in the cellular response when antigens are exposed on the cell surface. ..
  82. De Arcangelis A, Georges Labouesse E, Adams J. Expression of fascin-1, the gene encoding the actin-bundling protein fascin-1, during mouse embryogenesis. Gene Expr Patterns. 2004;4:637-43 pubmed
    ..Limb tendons appeared strongly positive. There was weak expression in heart ventricles. These results show that fascin-1 is principally expressed in neural and mesenchymal derivatives during embryonic development. ..
  83. Leclerc V, Pelte N, El Chamy L, Martinelli C, Ligoxygakis P, Hoffmann J, et al. Prophenoloxidase activation is not required for survival to microbial infections in Drosophila. EMBO Rep. 2006;7:231-5 pubmed
    ..This raises the question with regard to the precise function of phenoloxidase activation in defence, if any. ..
  84. Hu B, Nadiri A, Kuchler Bopp S, Perrin Schmitt F, Peters H, Lesot H. Tissue engineering of tooth crown, root, and periodontium. Tissue Eng. 2006;12:2069-75 pubmed
    ..Based on these results, we propose a refined strategy for tooth tissue engineering that may help to eventually generate morphologically defined teeth...
  85. Hechler B, Nonne C, Eckly A, Magnenat S, Rinckel J, Denis C, et al. Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization. J Thromb Haemost. 2010;8:173-84 pubmed publisher
    ..Collagen, VWF and thrombin all appear to contribute to thrombosis after deep arterial lesion. ..
  86. Masquida B, Beckert B, Jossinet F. Exploring RNA structure by integrative molecular modelling. N Biotechnol. 2010;27:170-83 pubmed publisher
    ..These aspects as well as the necessary steps towards automation will be discussed. ..
  87. Mathieu B, Delecolle J, Garros C, Balenghien T, Setier Rio M, Candolfi E, et al. Simultaneous quantification of the relative abundance of species complex members: application to Culicoides obsoletus and Culicoides scoticus (Diptera: Ceratopogonidae), potential vectors of bluetongue virus. Vet Parasitol. 2011;182:297-306 pubmed publisher
    ..This approach is an important contribution to medical entomology for investigating the vector role of arthropod sibling species...
  88. Zahid M, Turek M, Xiao F, Thi V, Guerin M, Fofana I, et al. The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination. Hepatology. 2013;57:492-504 pubmed publisher
    ..Interestingly, this postbinding function of SR-BI appears to be unrelated to HDL interaction but to be directly linked to its lipid transfer function...
  89. Philippe L, Alsaleh G, Pichot A, Ostermann E, Zuber G, Frisch B, et al. MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes. Ann Rheum Dis. 2013;72:1071-9 pubmed publisher
    ..Our data point toward an important role for miR-20a in the regulation of pro-inflammatory cytokines release, by controlling ASK1 expression in RA FLS. ..
  90. Collange O, Charles A, Bouitbir J, Chenard M, Zoll J, Diemunsch P, et al. Methylene blue protects liver oxidative capacity after gut ischaemia-reperfusion in the rat. Eur J Vasc Endovasc Surg. 2013;45:168-75 pubmed publisher
    ..Early impairment of liver mitochondrial respiration was related to blood lactate levels (r(2) = 0.45). MB restored liver mitochondrial function. MB protected against gut IR-induced liver mitochondria dysfunction. ..
  91. Lesage S, Drouet V, Majounie E, Deramecourt V, Jacoupy M, Nicolas A, et al. Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy. Am J Hum Genet. 2016;98:500-513 pubmed publisher
    ..This work suggests that loss of function of VPS13C is a cause of autosomal-recessive early-onset parkinsonism with a distinctive phenotype of rapid and severe progression. ..
  92. Van den Hooff P, Galvan M. Actions of 5-hydroxytryptamine and 5-HT1A receptor ligands on rat dorso-lateral septal neurones in vitro. Br J Pharmacol. 1992;106:893-9 pubmed
    ..7. It is concluded that the 5-HT-induced membrane hyperpolarization of rat dorso-lateral septal neurones is mediated by 5-HTA receptors. ..