Experts and Doctors on viola in Sweden

Summary

Locale: Sweden
Topic: viola

Top Publications

  1. Goransson U, Broussalis A, Claeson P. Expression of Viola cyclotides by liquid chromatography-mass spectrometry and tandem mass spectrometry sequencing of intercysteine loops after introduction of charges and cleavage sites by aminoethylation. Anal Biochem. 2003;318:107-17 pubmed
    ..The strategy for converting conserved cysteines to enzymatic cleavage sites might also benefit the study of other peptides and proteins displaying similar structural problems for MS analysis...
  2. Goransson U, Sjögren M, Svangård E, Claeson P, Bohlin L. Reversible antifouling effect of the cyclotide cycloviolacin O2 against barnacles. J Nat Prod. 2004;67:1287-90 pubmed
    ..Cycloviolacin O2 was isolated from the terrestrial plant Viola odorata by strong cation exchange and reversed-phase HPLC and identified by mass spectrometry following aminoethylation and enzymatic cleavage...
  3. Herrmann A, Burman R, Mylne J, Karlsson G, Gullbo J, Craik D, et al. The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity. Phytochemistry. 2008;69:939-52 pubmed publisher
    ..The IC(50)-values of the bracelet cyclotides vibi E, G and H ranged between 0.96 and 5.0 microM while the Möbius cyclotide vibi D was not cytotoxic at 30 microM...
  4. Pränting M, Lööv C, Burman R, Goransson U, Andersson D. The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria. J Antimicrob Chemother. 2010;65:1964-71 pubmed publisher
    ..To determine the antibacterial activity of small cyclic plant proteins, i.e. cyclotides, and the importance of the surface exposed charged residues for activity...
  5. Yeshak M, Burman R, Asres K, Goransson U. Cyclotides from an extreme habitat: characterization of cyclic peptides from Viola abyssinica of the Ethiopian highlands. J Nat Prod. 2011;74:727-31 pubmed publisher
  6. Marcussen T, Blaxland K, Windham M, Haskins K, Armstrong F. Establishing the phylogenetic origin, history, and age of the narrow endemic Viola guadalupensis (Violaceae). Am J Bot. 2011;98:1978-88 pubmed publisher
    ..Its affinities within Viola section Chamaemelanium have been the subject of some debate. Furthermore, the polyploid and presumably reticulate relationships within this section remain largely unknown...
  7. Lindholm P, Goransson U, Johansson S, Claeson P, Gullbo J, Larsson R, et al. Cyclotides: a novel type of cytotoxic agents. Mol Cancer Ther. 2002;1:365-9 pubmed
    ..This, together with the exceptional chemical and biological stability of cyclotides, makes them interesting in particular for their potential as pharmacological tools and possibly as leads to antitumor agents...
  8. Svangård E, Goransson U, Smith D, Verma C, Backlund A, Bohlin L, et al. Primary and 3-D modelled structures of two cyclotides from Viola odorata. Phytochemistry. 2003;64:135-42 pubmed
    ..The images of vodo M and vodo N show amphipathic structures with considerable surface hydrophobicity for a protein modelled in a polar environment...