Experts and Doctors on vascular remodeling in Germany
Topic: vascular remodeling
Krueger F, Kappert K, Foryst Ludwig A, Kramer F, Clemenz M, Grzesiak A, et al. AT1-receptor blockade attenuates outward aortic remodeling associated with diet-induced obesity in mice. Clin Sci (Lond). 2017;131:1989-2005 pubmed publisher
..The HFD-induced vascular pathology was reduced by AT1-receptor antagonist telmisartan. ..
Kammertoens T, Friese C, Arina A, Idel C, Briesemeister D, Rothe M, et al. Tumour ischaemia by interferon-? resembles physiological blood vessel regression. Nature. 2017;545:98-102 pubmed publisher
..A better mechanistic understanding of how solid tumours are rejected may aid the design of more effective protocols for adoptive T-cell therapy. ..
Hubert A, Bochenek M, Schütz E, Gogiraju R, Munzel T, Schafer K. Selective Deletion of Leptin Signaling in Endothelial Cells Enhances Neointima Formation and Phenocopies the Vascular Effects of Diet-Induced Obesity in Mice. Arterioscler Thromb Vasc Biol. 2017;37:1683-1697 pubmed publisher
..These observations and the identification of endothelin-1 as soluble mediator of the cardiovascular risk factor obesity may have relevant therapeutic implications. ..