Experts and Doctors on sperm head in United States


Locale: United States
Topic: sperm head

Top Publications

  1. Martin DeLeon P. Germ-cell hyaluronidases: their roles in sperm function. Int J Androl. 2011;34:e306-18 pubmed publisher
    ..Unsolved problems include functional redundancy, which can be addressed by double gene-knockouts, and identifying the murine hyase(s) involved in zona binding or whether this role shows species specificity. ..
  2. Connor W, Lin D, Wolf D, Alexander M. Uneven distribution of desmosterol and docosahexaenoic acid in the heads and tails of monkey sperm. J Lipid Res. 1998;39:1404-11 pubmed
    ..The large number of double bonds in DHA, six, and in desmosterol, two, may contribute to the membrane fluidity necessary for the motility of the sperm tails. ..
  3. Manier M, Lüpold S, Belote J, Starmer W, Berben K, Ala Honkola O, et al. Postcopulatory sexual selection generates speciation phenotypes in Drosophila. Curr Biol. 2013;23:1853-62 pubmed publisher
    ..This experimental approach to "speciation phenotypes" illustrates how knowledge of sperm precedence mechanisms can be used to predict the mechanisms and extent of reproductive isolation between populations and species. ..
  4. Huang Z, Vijayaraghavan S. Increased phosphorylation of a distinct subcellular pool of protein phosphatase, PP1gamma2, during epididymal sperm maturation. Biol Reprod. 2004;70:439-47 pubmed
    ..The distinct subcellular localization and changes in its level during sperm maturation suggest a possible role for sperm phosphorylated PP1gamma2 in signaling events during fertilization. ..
  5. Kolettis P, Burns J, Nangia A, Sandlow J. Outcomes for vasovasostomy performed when only sperm parts are present in the vasal fluid. J Androl. 2006;27:565-7 pubmed
    ..There does not appear to be a threshold obstructive interval above which VE would be indicated in this setting. If only an occasional sperm head is noted in the vasal fluid, then the surgeon should consider vasoepididymostomy. ..
  6. Antelman J, Manandhar G, Yi Y, Li R, Whitworth K, Sutovsky M, et al. Expression of mitochondrial transcription factor A (TFAM) during porcine gametogenesis and preimplantation embryo development. J Cell Physiol. 2008;217:529-43 pubmed publisher
    ..Altogether, our data on the role of TFAM in mitochondrial function and inheritance have broad implications for cell physiology and evolutionary biology. ..
  7. Manandhar G, Miranda Vizuete A, Pedrajas J, Krause W, Zimmerman S, Sutovsky M, et al. Peroxiredoxin 2 and peroxidase enzymatic activity of mammalian spermatozoa. Biol Reprod. 2009;80:1168-77 pubmed publisher
    ..Peroxidase activity in sperm extracts is not due to the glutathione system and therefore possibly involves PRDX2 and other peroxiredoxins. ..
  8. Manier M, Belote J, Berben K, Novikov D, Stuart W, Pitnick S. Resolving mechanisms of competitive fertilization success in Drosophila melanogaster. Science. 2010;328:354-7 pubmed publisher
    ..We find that competitive male fertilization success derives from a multivariate process involving ejaculate-female and ejaculate-ejaculate interactions, as well as complex sperm behavior in vivo...
  9. Yoon S, Fissore R. Release of phospholipase C zetaand [Ca2+]i oscillation-inducing activity during mammalian fertilization. Reproduction. 2007;134:695-704 pubmed

More Information


  1. Soler D, Kadunganattil S, Ramdas S, Myers K, Roca J, Slaughter T, et al. Expression of transgenic PPP1CC2 in the testis of Ppp1cc-null mice rescues spermatid viability and spermiation but does not restore normal sperm tail ultrastructure, sperm motility, or fertility. Biol Reprod. 2009;81:343-52 pubmed publisher
  2. Ala Honkola O, Manier M, Lüpold S, Pitnick S. No evidence for postcopulatory inbreeding avoidance in Drosophila melanogaster. Evolution. 2011;65:2699-705 pubmed publisher
    ..melanogaster. Analyses of mating latency, copulation duration, egg production rate, and remating interval further revealed no evidence for inbreeding avoidance. ..
  3. Higginson D, Henn K. Effects of sperm conjugation and dissociation on sperm viability in vitro. PLoS ONE. 2012;7:e34190 pubmed publisher
    ..Our results support the interpretation that, at least in some taxa, sperm conjugation is neither protective nor damaging to sperm viability. ..
  4. Wertheimer E, Krapf D, de la Vega Beltrán J, Sanchez Cardenas C, Navarrete F, Haddad D, et al. Compartmentalization of distinct cAMP signaling pathways in mammalian sperm. J Biol Chem. 2013;288:35307-20 pubmed publisher
    ..Altogether, these data suggest that cAMP pathways are compartmentalized in sperm, with Gs and tmAC in the head and Adcy10 and PKA in the flagellum. ..