Experts and Doctors on skeletal muscle in United States


Locale: United States
Topic: skeletal muscle

Top Publications

  1. Gerhart D, Enerson B, Zhdankina O, Leino R, Drewes L. Expression of the monocarboxylate transporter MCT2 by rat brain glia. Glia. 1998;22:272-81 pubmed
    ..The results lend support to the concept that astrocytes play a significant role in cerebral energy metabolism by transporting lactate and other monocarboxylates. ..
  2. Mozdziak P, Pulvermacher P, Schultz E. Unloading of juvenile muscle results in a reduced muscle size 9 wk after reloading. J Appl Physiol (1985). 2000;88:158-64 pubmed
    ..Juvenile soleus muscles failed to achieve normal muscle size 9 wk after reloading because there was incomplete compensation for the hindlimb-suspension-induced interruptions in myonuclear accretion and DNA unit size expansion...
  3. de Paula Brotto M, van Leyen S, Brotto L, Jin J, Nosek C, Nosek T. Hypoxia/fatigue-induced degradation of troponin I and troponin C: new insights into physiologic muscle fatigue. Pflugers Arch. 2001;442:738-44 pubmed
  4. Al Shekhlee A, Katirji B. Electrodiagnostic features of acute paralytic poliomyelitis associated with West Nile virus infection. Muscle Nerve. 2004;29:376-80 pubmed
    ..This report highlights the value of the electrodiagnostic studies in the diagnosis and prognosis of focal or generalized weakness due to acute paralytic poliomyelitis associated with WNV infection. ..
  5. Salihu H, Tchuinguem G, Aliyu M, Kouam L. Prune belly syndrome and associated malformations. A 13-year experience from a developing country. West Indian Med J. 2003;52:281-4 pubmed
    ..In conclusion, Cameroonian babies with prune belly syndrome presented with clinical features that were comparable to those observed in developed nations. ..
  6. Starnes J, Choilawala A, Taylor R, Nelson M, Delp M. Myocardial heat shock protein 70 expression in young and old rats after identical exercise programs. J Gerontol A Biol Sci Med Sci. 2005;60:963-9 pubmed
    ..Our results indicate an age-related decrease in HSP70 production in heart and liver following chronic exercise. Furthermore, the aged heart does not increase its antioxidant enzyme defenses to compensate for the HSP70 deficit. ..
  7. Atit R, Sgaier S, Mohamed O, Taketo M, Dufort D, Joyner A, et al. Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. Dev Biol. 2006;296:164-76 pubmed
    ..Our results indicate that the mouse central dermomyotome gives rise to dermis, muscle, and brown fat, and that Wnt signalling normally instructs cells to select the dorsal dermal fate. ..
  8. Wang H, Sorenson E, Spinner R, Windebank A. Electrophysiologic findings and grip strength after nerve injuries in the rat forelimb. Muscle Nerve. 2008;38:1254-65 pubmed publisher
    ..We conclude that it is possible to conduct minimally invasive electrophysiologic testing in rat forelimbs. The CMAP is a valid parameter that shows the typical time course of nerve regeneration and reinnervation. ..
  9. Hilton G, Montgomery J, Krehbiel C, Yates D, Hutcheson J, Nichols W, et al. Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers. J Anim Sci. 2009;87:1394-406 pubmed publisher
    ..07). Zilpaterol is a strong repartitioning agent that increases meat yield through increased protein and decreased fat deposition. ..

More Information

Publications326 found, 100 shown here

  1. Sorenson E, Chen J, Daube J. Obturator neuropathy: causes and outcome. Muscle Nerve. 2002;25:605-7 pubmed
    ..Twenty-two patients with obturator neuropathy were identified. The clinical outcome of patients with acute obturator neuropathy treated conservatively was good regardless of etiology or severity. ..
  2. Bamman M, Hill V, Adams G, Haddad F, Wetzstein C, Gower B, et al. Gender differences in resistance-training-induced myofiber hypertrophy among older adults. J Gerontol A Biol Sci Med Sci. 2003;58:108-16 pubmed
    ..05). In summary, gender differences in load-induced myofiber hypertrophy among older adults cannot be explained by levels of circulating IGF-1 or dehydroepiandrosterone sulfate, or by expression of the myogenic transcripts examined. ..
  3. Staud R, Cannon R, Mauderli A, Robinson M, Price D, Vierck C. Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome. Pain. 2003;102:87-95 pubmed
    ..Abnormal input from muscle nociceptors appears to underlie production of central sensitization in FMS that generalizes to input from cutaneous nociceptors. ..
  4. Jin J, Brotto M, Hossain M, Huang Q, Brotto L, Nosek T, et al. Truncation by Glu180 nonsense mutation results in complete loss of slow skeletal muscle troponin T in a lethal nemaline myopathy. J Biol Chem. 2003;278:26159-65 pubmed
    ..These results lay the foundation for understanding the molecular pathophysiology and the potential targeted therapy of ANM. ..
  5. Burneo J, Arnold T, Palmer C, Kuzniecky R, Oh S, Faught E. Adult-onset neuronal ceroid lipofuscinosis (Kufs disease) with autosomal dominant inheritance in Alabama. Epilepsia. 2003;44:841-6 pubmed
  6. Felice K, Jones J, Conway S. Facioscapulohumeral dystrophy presenting as infantile facial diplegia and late-onset limb-girdle myopathy in members of the same family. Muscle Nerve. 2005;32:368-72 pubmed
    ..In difficult cases, facial muscle electromyography may help to differentiate myopathic from neuropathic weakness, and help guide further diagnostic studies. ..
  7. Jeftinija D, Wang Q, Hebert S, Norris C, Yan Z, Rich M, et al. The Ca(V) 1.2 Ca(2+) channel is expressed in sarcolemma of type I and IIa myofibers of adult skeletal muscle. Muscle Nerve. 2007;36:482-90 pubmed
    ..2 and type IIa-positive fibers. Taken together, these data suggest that the Ca(V) 1.2 Ca(2+) channel is expressed in adult skeletal muscle in a fiber type-specific manner, which may help to maintain oxidative muscle phenotype. ..
  8. Bakkar N, Wang J, Ladner K, Wang H, Dahlman J, Carathers M, et al. IKK/NF-kappaB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis. J Cell Biol. 2008;180:787-802 pubmed publisher
    ..Together, these data reveal a unique IKK/NF-kappaB signaling switch that functions to both inhibit differentiation and promote myotube homeostasis. ..
  9. Mortazavi A, Williams B, McCue K, Schaeffer L, Wold B. Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods. 2008;5:621-8 pubmed publisher
    ..We observed 1.45 x 10(5) distinct splices, and alternative splices were prominent, with 3,500 different genes expressing one or more alternate internal splices. ..
  10. Marzetti E, Wohlgemuth S, Lees H, Chung H, Giovannini S, Leeuwenburgh C. Age-related activation of mitochondrial caspase-independent apoptotic signaling in rat gastrocnemius muscle. Mech Ageing Dev. 2008;129:542-9 pubmed publisher
    ..Our findings indicate that the mitochondrial caspase-independent apoptotic pathway may play a more prominent role in skeletal muscle loss than caspase-mediated apoptosis. ..
  11. Galvez R, Stacy J, Howley A. Exertional rhabdomyolysis in seven division-1 swimming athletes. Clin J Sport Med. 2008;18:366-8 pubmed publisher
  12. Wu F, Wilson J. Peroxynitrite-dependent activation of protein phosphatase type 2A mediates microvascular endothelial barrier dysfunction. Cardiovasc Res. 2009;81:38-45 pubmed publisher
    ..This nitration in PP2Ac is correlated with PP2A activation that mediates endothelial barrier dysfunction. ..
  13. Fattah A, Figus A, Mathur B, Ramakrishnan V. The transverse myocutaneous gracilis flap: technical refinements. J Plast Reconstr Aesthet Surg. 2010;63:305-13 pubmed publisher
    ..It is also a reliable salvage flap in cases of previous flap failure. ..
  14. Hogan K, Powers P, Gregg R. Cloning of the human skeletal muscle alpha 1 subunit of the dihydropyridine-sensitive L-type calcium channel (CACNL1A3). Genomics. 1994;24:608-9 pubmed
  15. Venema V, Ju H, Zou R, Venema R. Interaction of neuronal nitric-oxide synthase with caveolin-3 in skeletal muscle. Identification of a novel caveolin scaffolding/inhibitory domain. J Biol Chem. 1997;272:28187-90 pubmed
    ..Inhibitory interactions mediated by two different caveolin domains may thus be a general feature of enzyme docking to caveolin proteins in plasmalemmal caveolae. ..
  16. Balagopal P, Rooyackers O, Adey D, Ades P, Nair K. Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans. Am J Physiol. 1997;273:E790-800 pubmed
    ..01). A decline in the synthesis rate of myosin heavy chain implies a decreased ability to remodel this important muscle contractile protein and likely contributes to the declining muscle mass and contractile function in the elderly. ..
  17. Kirwan J, Del Aguila L, Hernandez J, Williamson D, O Gorman D, Lewis R, et al. Regular exercise enhances insulin activation of IRS-1-associated PI3-kinase in human skeletal muscle. J Appl Physiol (1985). 2000;88:797-803 pubmed
    ..60, P < 0.02). We conclude that regular exercise leads to greater insulin-stimulated IRS-1-associated PI3-kinase activation in human skeletal muscle, thus facilitating enhanced insulin-mediated glucose uptake...
  18. Talwalkar S, Parker J, Heffner R, Parker J. Adult central core disease. Clinical, histologic and genetic aspects: case report and review of the literature. Clin Neuropathol. 2006;25:180-4 pubmed
    ..We describe a 58-year-old man diagnosed with CCD, who is one of the oldest individuals reported with CCD diagnosed by a muscle biopsy. The clinical, pathological and genetic features of this rare entity are discussed herein...
  19. Souayah N, Karim H, Kamin S, McArdle J, Marcus S. Severe botulism after focal injection of botulinum toxin. Neurology. 2006;67:1855-6 pubmed
    ..Electrophysiologic findings demonstrated complete denervation with complete electrical silence. She had a lengthy recovery but was able to ambulate by discharge. ..
  20. Liu M, Walter G, Pathare N, Forster R, Vandenborne K. A quantitative study of bioenergetics in skeletal muscle lacking carbonic anhydrase III using 31P magnetic resonance spectroscopy. Proc Natl Acad Sci U S A. 2007;104:371-6 pubmed
    ..Because the tension decrease during fatigue is known to be the same in the two genotypes, we conclude that a lack of CA III impairs mitochondrial ATP synthesis. ..
  21. Bansode R, Huang W, Roy S, Mehta M, Mehta K. Protein kinase C deficiency increases fatty acid oxidation and reduces fat storage. J Biol Chem. 2008;283:231-6 pubmed
    ..The ability of PKCbeta deficiency to promote fat burning in adipocytes may suggest novel therapeutic strategies for obesity and obesity-related disorders. ..
  22. Rotwein P, Wilson E. Distinct actions of Akt1 and Akt2 in skeletal muscle differentiation. J Cell Physiol. 2009;219:503-11 pubmed publisher
    ..Our results define isoform-specific Akt actions in muscle cells, and demonstrate that both Akts are necessary for full myoblast differentiation and maturation. ..
  23. Barbour A, Schmidt S, Rout W, Ben David K, Burkhardt O, Derendorf H. Soft tissue penetration of cefuroxime determined by clinical microdialysis in morbidly obese patients undergoing abdominal surgery. Int J Antimicrob Agents. 2009;34:231-5 pubmed publisher
    ..Concentrations in the ISF of soft tissues following a single 1.5 g dose may be high enough to prevent infections with Gram-positive organisms but may be insufficient to prevent infections with Gram-negative organisms. ..
  24. Xu R, DeVries S, Camboni M, Martin P. Overexpression of Galgt2 reduces dystrophic pathology in the skeletal muscles of alpha sarcoglycan-deficient mice. Am J Pathol. 2009;175:235-47 pubmed publisher
  25. Smith W, Fetz E. Synaptic linkages between corticomotoneuronal cells affecting forelimb muscles in behaving primates. J Neurophysiol. 2009;102:1040-8 pubmed publisher
    ..Reconstruction of the cortical locations of CM cells affecting 12 different muscles showed a wide and overlapping distribution of cortical colonies of forelimb muscles. ..
  26. Lee R, Tikunova S, Kline K, Zot H, Hasbun J, Minh N, et al. Effect of Ca2+ binding properties of troponin C on rate of skeletal muscle force redevelopment. Am J Physiol Cell Physiol. 2010;299:C1091-9 pubmed publisher
    ..Thus TnC mutants with altered Ca(2+) binding properties can control the rate of contraction by modulating thin filament activation without directly affecting intrinsic cross-bridge cycling rates...
  27. Adams M, Anderson K, Froehner S. The alpha-syntrophin PH and PDZ domains scaffold acetylcholine receptors, utrophin, and neuronal nitric oxide synthase at the neuromuscular junction. J Neurosci. 2010;30:11004-10 pubmed publisher
    ..We conclude that the PH1 and PDZ domains of alpha-syntrophin work in concert to facilitate the localization of AChRs and nNOS at the NMJ. ..
  28. Behnke B, McDonough P, Padilla D, Musch T, Poole D. Oxygen exchange profile in rat muscles of contrasting fibre types. J Physiol. 2003;549:597-605 pubmed
  29. Heinrich G. A novel BDNF gene promoter directs expression to skeletal muscle. BMC Neurosci. 2003;4:11 pubmed
    ..They can now be subjected to detailed molecular and genetic analyses to identify the cellular mechanisms by which the transcription factors that act on these regions control BDNF gene expression. ..
  30. Ryan N, Zwetsloot K, Westerkamp L, Hickner R, Pofahl W, Gavin T. Lower skeletal muscle capillarization and VEGF expression in aged vs. young men. J Appl Physiol (1985). 2006;100:178-85 pubmed
    ..There were no effects of exercise or age on muscle Flt-1 mRNA or protein or KDR protein. These results confirm that skeletal muscle capillarization and VEGF expression are lower in aged compared with young men. ..
  31. Samerotte A, Drazen J, Brand G, Seibel B, Yancey P. Correlation of trimethylamine oxide and habitat depth within and among species of teleost fish: an analysis of causation. Physiol Biochem Zool. 2007;80:197-208 pubmed
    ..Overall, the data strongly support the hypothesis that TMAO is adaptively regulated with depth in deep-sea teleosts. Whether lipid metabolism is the source of that TMAO is a question that remains to be tested fully. ..
  32. Forgacs E, Cartwright S, Sakamoto T, Sellers J, Corrie J, Webb M, et al. Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power stroke. J Biol Chem. 2008;283:766-73 pubmed
    ..The dissociation of ADP from the lead head is decreased by up to 250-fold. ..
  33. Hooper S, Hobbs K, Thuma J. Invertebrate muscles: thin and thick filament structure; molecular basis of contraction and its regulation, catch and asynchronous muscle. Prog Neurobiol. 2008;86:72-127 pubmed publisher
    ..The molecular basis of the stretch activation underlying asynchronous muscle activity, however, remains unresolved. ..
  34. Hodnett B, Xiang L, Dearman J, Carter C, Hester R. K(ATP)-mediated vasodilation is impaired in obese Zucker rats. Microcirculation. 2008;15:485-94 pubmed publisher
    ..Channel subunit expression was similar in femoral arteries. The impaired functional vasodilation in the OZR is associated with altered K(ATP) channel sensitivity. ..
  35. Blana D, Kirsch R, Chadwick E. Combined feedforward and feedback control of a redundant, nonlinear, dynamic musculoskeletal system. Med Biol Eng Comput. 2009;47:533-42 pubmed publisher
  36. Pandya K, Radke F. Benign skin lesions: lipomas, epidermal inclusion cysts, muscle and nerve biopsies. Surg Clin North Am. 2009;89:677-87 pubmed publisher
    ..Although the procedures are straightforward, there are important technical issues to assist in getting the best specimen to avoid confounding disease diagnosis. ..
  37. Medeiros E, Phelps M, Fuentes F, Bradley T. Overexpression of follistatin in trout stimulates increased muscling. Am J Physiol Regul Integr Comp Physiol. 2009;297:R235-42 pubmed publisher
    ..It remains to be determined whether the double muscling in trout is due to inhibition of myostatin, other growth factors, or both...
  38. Hogan K, Gregg R, Powers P. The structure of the gene encoding the human skeletal muscle alpha 1 subunit of the dihydropyridine-sensitive L-type calcium channel (CACNL1A3). Genomics. 1996;31:392-4 pubmed
    ..Knowledge of the genomic structure of the CACNL1A3 gene, which spans 90 kb and consists of 44 exons, will facilitate the search for additional mutations in CACNL1A3 that cause neuromuscular disease. ..
  39. Garvey W, Maianu L, Zhu J, Brechtel Hook G, Wallace P, Baron A. Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance. J Clin Invest. 1998;101:2377-86 pubmed
    ..Based on these data, we propose that human insulin resistance involves a defect in GLUT4 traffic and targeting leading to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface. ..
  40. Mal A, Sturniolo M, Schiltz R, Ghosh M, Harter M. A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program. EMBO J. 2001;20:1739-53 pubmed
    ..These results provide for a model which postulates that MyoD may be co-dependent on HDAC1 and P/CAF for temporally controlling its transcriptional activity before and after the differentiation of muscle cells. ..
  41. Ahern C, Powers P, Biddlecome G, Roethe L, Vallejo P, Mortenson L, et al. Modulation of L-type Ca2+ current but not activation of Ca2+ release by the gamma1 subunit of the dihydropyridine receptor of skeletal muscle. BMC Physiol. 2001;1:8 pubmed
    ..voltage relationship as control myotubes. The L-type Ca2+ channel function, but not the SR Ca2+ release triggering function of the skeletal muscle dihydropyridine receptor, is modulated by the gamma1 subunit. ..
  42. Clark B, Manini T, Mayer J, Ploutz Snyder L, Graves J. Electromyographic activity of the lumbar and hip extensors during dynamic trunk extension exercise. Arch Phys Med Rehabil. 2002;83:1547-52 pubmed
    ..These findings raise questions as to the efficacy of added loading and multiple sets during trunk extension exercise. ..
  43. Alvarez G, Beske S, Ballard T, Davy K. Sympathetic neural activation in visceral obesity. Circulation. 2002;106:2533-6 pubmed
    ..Furthermore, these findings may have important implications for understanding the increased risk of developing cardiovascular diseases in individuals with visceral obesity. ..
  44. Lan H, Rabaglia M, Stoehr J, Nadler S, Schueler K, Zou F, et al. Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility. Diabetes. 2003;52:688-700 pubmed
    ..We propose that increased hepatic lipogenic capacity protects the B6-ob/ob mice from the development of type 2 diabetes. ..
  45. Gu J, Fortepiani L, Reckelhoff J, Adair T, Wang J, Hall J. Increased expression of vascular endothelial growth factor and capillary density in hearts of spontaneously hypertensive rats. Microcirculation. 2004;11:689-97 pubmed
    ..The data are consistent with the possibility that VEGF may contribute to capillary growth as a compensatory response to hypertension. ..
  46. Borst S, Conover C, Bagby G. Association of resistin with visceral fat and muscle insulin resistance. Cytokine. 2005;32:39-44 pubmed
    ..Elevation of circulating cytokines may play a role in the development of muscle insulin resistance. ..
  47. Mast B, Simoneau D. Latissimus dorsi breast reconstruction utilizing functional muscle transfer and tissue expansion. Ann Plast Surg. 2006;56:36-9 pubmed
    ..All patients demonstrated excellent retention of breast shape/definition. This study demonstrates that functional muscle transfer and tissue expansion results in low capsular contracture rates and excellent retained breast shape. ..
  48. O Leary V, Jorett A, Marchetti C, Gonzalez F, Phillips S, Ciaraldi T, et al. Enhanced adiponectin multimer ratio and skeletal muscle adiponectin receptor expression following exercise training and diet in older insulin-resistant adults. Am J Physiol Endocrinol Metab. 2007;293:E421-7 pubmed
    ..03, AdipoR2 P < 0.02). These data suggest that part of the improvement in insulin sensitivity following exercise and diet may be due to changes in the adiponectin oligomeric distribution and enhanced membrane receptor expression. ..
  49. Liu M, Yue Y, Li D, Duan D. Catalase overexpression does not impair extensor digitorum longus muscle function in normal mice. Muscle Nerve. 2007;36:833-41 pubmed
    ..Taken together, we have developed a novel AAV vector to enhance catalase expression. Lack of apparent toxicity in normal muscle strongly supports further exploration of this vector to reduce oxidative stress-induced muscle damage. ..
  50. Otis J, Brown L, Guidot D. Oxidant-induced atrogin-1 and transforming growth factor-beta1 precede alcohol-related myopathy in rats. Muscle Nerve. 2007;36:842-8 pubmed
    ..Therefore, targeted anti-oxidant treatments such as procysteine supplementation may benefit individuals with chronic alcohol abuse, particularly if given prior to the development of clinically significant myopathy. ..
  51. Kibler W, Sciascia A, Uhl T, Tambay N, Cunningham T. Electromyographic analysis of specific exercises for scapular control in early phases of shoulder rehabilitation. Am J Sports Med. 2008;36:1789-98 pubmed publisher
    ..Inferior glide and low row can be performed early in rehabilitation because of their limited range of motion, while lawnmower and robbery, which require larger movements, can be instituted later in the sequence. ..
  52. Gupte A, Bomhoff G, Geiger P. Age-related differences in skeletal muscle insulin signaling: the role of stress kinases and heat shock proteins. J Appl Physiol (1985). 2008;105:839-48 pubmed publisher
    ..A greater constitutive HSP expression and lower stress kinase activation may account for the ability of slow-twitch muscles to preserve the capacity to respond to insulin and maintain glucose homeostasis with age. ..
  53. Casey D, Curry T, Joyner M. Measuring muscle blood flow: a key link between systemic and regional metabolism. Curr Opin Clin Nutr Metab Care. 2008;11:580-6 pubmed publisher
    ..Recognizing the advantages and limitations of each technique is essential to translational researchers studying the effects of nutrition and metabolism on muscle blood flow. ..
  54. Chumanov E, Wall Scheffler C, Heiderscheit B. Gender differences in walking and running on level and inclined surfaces. Clin Biomech (Bristol, Avon). 2008;23:1260-8 pubmed publisher
    ..Our findings indicate females display greater non-sagittal motion. Future studies are needed to better define the relationship of these differences to injury risk. ..
  55. Masi A, Hannon J. Human resting muscle tone (HRMT): narrative introduction and modern concepts. J Bodyw Mov Ther. 2008;12:320-32 pubmed publisher
    ..Interdisciplinary research on HRMT and its biodynamics promises greater effectiveness of clinical practitioners and productivity of investigators, which warrants priority attention. ..
  56. Gomes F, Rezende E, Malisch J, Lee S, Rivas D, Kelly S, et al. Glycogen storage and muscle glucose transporters (GLUT-4) of mice selectively bred for high voluntary wheel running. J Exp Biol. 2009;212:238-48 pubmed publisher
    ..All mice showed some glycogen depletion during nightly wheel running, in muscles and/or liver, but the magnitude of this depletion was not large and hence does not seem to be limiting to the evolution of even-higher wheel running. ..
  57. Miyazaki M, Esser K. REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch. Am J Physiol Cell Physiol. 2009;296:C583-92 pubmed publisher
    ..These findings demonstrate that REDD2 is a skeletal muscle specific inhibitory modulator of mTOR signaling and identify TSC2 and 14-3-3 as key molecular links between REDD2 and mTOR function. ..
  58. McMullen C, Ferry A, Gamboa J, Andrade F, Dupont Versteegden E. Age-related changes of cell death pathways in rat extraocular muscle. Exp Gerontol. 2009;44:420-5 pubmed publisher
    ..Based on these data, we suggest that the decrease in autophagy with age leads to the accumulation of damaged organelles, particularly mitochondria, which results in the decrease in function observed in EOM with age. ..
  59. Choi H, Selpides P, Nowell M, Rourke B. Functional overload in ground squirrel plantaris muscle fails to induce myosin isoform shifts. Am J Physiol Regul Integr Comp Physiol. 2009;297:R578-86 pubmed publisher
  60. Siegel A, Atchison K, Fisher K, Davis G, Cornelison D. 3D timelapse analysis of muscle satellite cell motility. Stem Cells. 2009;27:2527-38 pubmed publisher
    ..Together, these data suggest that satellite cell migration in vivo may be more extensive than currently thought, and could be regulated by combinations of signals, including adhesive haptotaxis, soluble factors, and guidance cues. ..
  61. Mendell J, Rodino Klapac L, Rosales Quintero X, Kota J, Coley B, Galloway G, et al. Limb-girdle muscular dystrophy type 2D gene therapy restores alpha-sarcoglycan and associated proteins. Ann Neurol. 2009;66:290-7 pubmed publisher
    ..Sustained gene expression was seen, but studies over longer time periods without immunotherapy will be required for design of vascular delivery gene therapy trials. ..
  62. Roseguini B, Davis M, Harold Laughlin M. Rapid vasodilation in isolated skeletal muscle arterioles: impact of branch order. Microcirculation. 2010;17:83-93 pubmed publisher
    ..Furthermore, the average TD before vasodilation supports a role for metabolic signals as contributors to the ROV. ..
  63. Marras W, Granata K. Changes in trunk dynamics and spine loading during repeated trunk exertions. Spine (Phila Pa 1976). 1997;22:2564-70 pubmed
    ..This study has shown that spine loading patterns do indeed change with repetition, suggesting that one needs to monitor these changes throughout repetitive lifting tasks if low back disorder risk is to be minimized. ..
  64. Hamrick M, McPherron A, Lovejoy C, Hudson J. Femoral morphology and cross-sectional geometry of adult myostatin-deficient mice. Bone. 2000;27:343-9 pubmed
  65. Sreekumar R, Unnikrishnan J, Fu A, Nygren J, Short K, Schimke J, et al. Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscle. Am J Physiol Endocrinol Metab. 2002;283:E38-43 pubmed
    ..Alterations in transcripts of many genes involved in reactive oxygen scavenging function may contribute to the increase in longevity reported with CR. ..
  66. Cheadle M, Cunningham M, Greiner E. Prevalence of sarcocysts in Florida black bears (Ursus americanus floridanus). J Parasitol. 2002;88:629-30 pubmed
    ..Two of 132 (1.5%) black bears had muscle sections containing sarcocysts. One sarcocyst was observed per muscle section. The sarcocysts averaged 181.5 x 99.0 microm by light microscopy of hematoxylin and eosin-stained sections. ..
  67. Dirks A, Leeuwenburgh C. Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12. Free Radic Biol Med. 2004;36:27-39 pubmed
    ..Calorie restriction is able to lower the apoptotic potential in aged skeletal muscle by altering several key apoptotic proteins toward cellular survival, thereby reducing the potential for sarcopenia. ..
  68. Kobayashi S, Yamamoto T, Parness J, Ikemoto N. Antibody probe study of Ca2+ channel regulation by interdomain interaction within the ryanodine receptor. Biochem J. 2004;380:561-9 pubmed
  69. Smith J, Haney J. Foodweb transfer, accumulation, and depuration of microcystins, a cyanobacterial toxin, in pumpkinseed sunfish (Lepomis gibbosus). Toxicon. 2006;48:580-9 pubmed
    ..Sunfish retained MC in their liver and muscle tissue, showing no significant changes in toxin concentration over 2 weeks of fasted depuration. ..
  70. Heatwole C, Moxley R. The nondystrophic myotonias. Neurotherapeutics. 2007;4:238-51 pubmed
  71. Palmer B, Suzuki T, Wang Y, Barnes W, Miller M, Maughan D. Two-state model of acto-myosin attachment-detachment predicts C-process of sinusoidal analysis. Biophys J. 2007;93:760-9 pubmed
    ..Experimental results from activated cardiac muscle examined at different temperatures and containing predominately alpha- or beta-myosin heavy chain isoforms were found to be consistent with the above interpretation. ..
  72. Marcinek D, Amara C, Matz K, Conley K, Schenkman K. Wavelength shift analysis: a simple method to determine the contribution of hemoglobin and myoglobin to in vivo optical spectra. Appl Spectrosc. 2007;61:665-9 pubmed
    ..This advance will facilitate comparison of the metabolic properties between individual muscles and provides a fully noninvasive approach to measuring local respiration that can be adapted for clinical use. ..
  73. Zhao Y, Zeng H, Nam J, Agarwal S. Fabrication of skeletal muscle constructs by topographic activation of cell alignment. Biotechnol Bioeng. 2009;102:624-31 pubmed publisher
    ..The findings demonstrate that the on-chip device holds promise for providing an efficient means for guided muscle tissue construction. ..
  74. Hortobagyi T, Solnik S, Gruber A, Rider P, Steinweg K, Helseth J, et al. Interaction between age and gait velocity in the amplitude and timing of antagonist muscle coactivation. Gait Posture. 2009;29:558-64 pubmed publisher
    ..015). It is concluded that there is an interaction between age and gait velocity in the amplitude and timing of antagonist muscle coactivation. ..
  75. Mudalige W, Tao T, Lehrer S. Ca2+-dependent photocrosslinking of tropomyosin residue 146 to residues 157-163 in the C-terminal domain of troponin I in reconstituted skeletal muscle thin filaments. J Mol Biol. 2009;389:575-83 pubmed publisher
    ..Tm muscle thin filaments. ..
  76. Shin G, D Souza C, Liu Y. Creep and fatigue development in the low back in static flexion. Spine (Phila Pa 1976). 2009;34:1873-8 pubmed publisher
    ..In vivo measurements of low back flexion posture and muscle activity before, during, and after static flexion...
  77. Dowthwaite J, Scerpella T. Skeletal geometry and indices of bone strength in artistic gymnasts. J Musculoskelet Neuronal Interact. 2009;9:198-214 pubmed
    ..Further research is necessary to address sex-, maturity- and bone tissue-specific adaptation, as well as maintenance of benefits beyond loading cessation. ..
  78. Asakura A, Lyons G, Tapscott S. The regulation of MyoD gene expression: conserved elements mediate expression in embryonic axial muscle. Dev Biol. 1995;171:386-98 pubmed
    ..The functional conservation of the regulatory region of the mouse myoD gene in Xenopus embryos suggests that the regulatory pathway that activates myoD gene transcription in axial muscles is conserved among vertebrates. ..
  79. Chen L, Lo C, Numann R, Cuddy M. Characterization of the human and rat phospholemman (PLM) cDNAs and localization of the human PLM gene to chromosome 19q13.1. Genomics. 1997;41:435-43 pubmed
    ..The high degree of sequence and functional conservation among the mammalian PLM proteins indicates that this gene is conserved throughout evolution. ..
  80. Halliwill J. Segregated signal averaging of sympathetic baroreflex responses in humans. J Appl Physiol (1985). 2000;88:767-73 pubmed
    ..This approach provides an objective, rapid method to analyze nerve recordings...
  81. Luo Y, Davis J, Smillie L, Rall J. Determinants of relaxation rate in rabbit skinned skeletal muscle fibres. J Physiol. 2002;545:887-901 pubmed
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