Experts and Doctors on saccharomyces cerevisiae proteins in Australia


Locale: Australia
Topic: saccharomyces cerevisiae proteins

Top Publications

  1. Squires J, Preiss T. Function and detection of 5-methylcytosine in eukaryotic RNA. Epigenomics. 2010;2:709-15 pubmed publisher
    ..In this article we review the occurrence, function and biochemical detection of m(5)C in eukaryotic RNA, and provide perspectives on the biological roles of this modification in the transcriptome. ..
  2. Sinclair D, Dawes I. Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae. Genetics. 1995;140:1213-22 pubmed
    ..Representatives from three complementation groups were also unable to grow on glycine as sole nitrogen source (gsd1-3). Assays of the rate of glycine uptake and decarboxylation have provided insights into the nature of the mutations. ..
  3. Couttas T, Raftery M, Padula M, Herbert B, Wilkins M. Methylation of translation-associated proteins in Saccharomyces cerevisiae: Identification of methylated lysines and their methyltransferases. Proteomics. 2012;12:960-72 pubmed publisher
    ..We suggest that enzyme YBR271W is named EF methyltransferase 2 (Efm2), in line with the recent naming of YHL039W as Efm1. ..
  4. Brymora A, Valova V, Larsen M, Roufogalis B, Robinson P. The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene. J Biol Chem. 2001;276:29792-7 pubmed
    ..Phospholipase D bound RalA in a nucleotide-independent manner. This places the RalA signaling system in mammalian nerve terminals, where the exocyst may act as an effector for activated RalA in directing sites of exocytosis. ..
  5. Senapin S, Clark Walker G, Chen X, Seraphin B, Daugeron M. RRP20, a component of the 90S preribosome, is required for pre-18S rRNA processing in Saccharomyces cerevisiae. Nucleic Acids Res. 2003;31:2524-33 pubmed
    ..As the protein encoded by YOR145c is found in pre-ribosomal particles and the mutant strain is defective in ribosomal RNA processing, we have renamed it as RRP20. ..
  6. Gecz J, Shaw M, Bellon J, de Barros Lopes M. Human wild-type SEDL protein functionally complements yeast Trs20p but some naturally occurring SEDL mutants do not. Gene. 2003;320:137-44 pubmed
  7. Vajjhala P, Catchpoole E, Nguyen C, Kistler C, Munn A. Vps4 regulates a subset of protein interactions at the multivesicular endosome. FEBS J. 2007;274:1894-907 pubmed
    ..Our studies indicate that the MIT domain has a dual role in substrate binding and recruitment to endosomes and indicate that Vps4 disassembles the MVB sorting machinery by direct effects on multiple proteins. ..
  8. Fong C, Temple M, Alic N, Chiu J, Durchdewald M, Thorpe G, et al. Oxidant-induced cell-cycle delay in Saccharomyces cerevisiae: the involvement of the SWI6 transcription factor. FEMS Yeast Res. 2008;8:386-99 pubmed publisher
    ..These data show that functions such as heat shock response, and glucose transport are involved in the response. ..
  9. Tsoi B, Beckhouse A, Gelling C, Raftery M, Chiu J, Tsoi A, et al. Essential role of one-carbon metabolism and Gcn4p and Bas1p transcriptional regulators during adaptation to anaerobic growth of Saccharomyces cerevisiae. J Biol Chem. 2009;284:11205-15 pubmed publisher
    ..During anaerobic starvation for l-serine, this essential amino acid is preferentially directed to the cell wall, indicating the existence of a regulatory mechanism to balance competing cellular demands. ..

More Information


  1. Low J, Hart Smith G, Erce M, Wilkins M. Analysis of the proteome of Saccharomyces cerevisiae for methylarginine. J Proteome Res. 2013;12:3884-99 pubmed publisher
  2. Holt S, Cordente A, Williams S, Capone D, Jitjaroen W, Menz I, et al. Engineering Saccharomyces cerevisiae to release 3-Mercaptohexan-1-ol during fermentation through overexpression of an S. cerevisiae Gene, STR3, for improvement of wine aroma. Appl Environ Microbiol. 2011;77:3626-32 pubmed publisher
    ..These data provide direct evidence for a yeast enzyme able to release aromatic thiols in vitro that can be applied in the development of self-cloned yeast to enhance wine flavor. ..
  3. Gauci V, Beckhouse A, Lyons V, Beh E, Rogers P, Dawes I, et al. Zinc starvation induces a stress response in Saccharomyces cerevisiae that is mediated by the Msn2p and Msn4p transcriptional activators. FEMS Yeast Res. 2009;9:1187-95 pubmed publisher
    ..This research provides a better understanding of the molecular mechanisms involved in the yeast response to zinc deficiency during fermentation. ..
  4. Huang K, Filarsky M, Padula M, Raftery M, Herbert B, Wilkins M. Micropreparative fractionation of the complexome by blue native continuous elution electrophoresis. Proteomics. 2009;9:2494-502 pubmed publisher
    ..We illustrate the utility of the technique in the analysis of Saccharomyces cerevisiae cellular lysate. ..
  5. Vajjhala P, Nguyen C, Landsberg M, Kistler C, Gan A, King G, et al. The Vps4 C-terminal helix is a critical determinant for assembly and ATPase activity and has elements conserved in other members of the meiotic clade of AAA ATPases. FEBS J. 2008;275:1427-49 pubmed publisher
    ..We propose that Vps4 SRH function requires an intact C-terminal helix. Co-evolution of a distinct Vps4 SRH and C-terminal helix in meiotic clade AAA ATPases supports this possibility. ..
  6. Southey M, Jenkins M, Mead L, Whitty J, Trivett M, Tesoriero A, et al. Use of molecular tumor characteristics to prioritize mismatch repair gene testing in early-onset colorectal cancer. J Clin Oncol. 2005;23:6524-32 pubmed
    ..Tumor-based approaches for triaging early-onset colorectal cancer patients for MMR gene mutation testing, irrespective of family history, appear to be an efficient screening strategy for HNPCC. ..
  7. Senapin S, Chen X, Clark Walker G. Transcription of TIM9, a new factor required for the petite-positive phenotype of Saccharomyces cerevisiae, is defective in spt7 mutants. Curr Genet. 2003;44:202-10 pubmed
  8. Utama B, Kennedy D, Ru K, Mattick J. Isolation and characterization of a new nucleolar protein, Nrap, that is conserved from yeast to humans. Genes Cells. 2002;7:115-32 pubmed
    ..Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript. ..
  9. Holmgreen S, Huang D, Adams J, Cory S. Survival activity of Bcl-2 homologs Bcl-w and A1 only partially correlates with their ability to bind pro-apoptotic family members. Cell Death Differ. 1999;6:525-32 pubmed
    ..The results may reflect critical threshold affinities but also suggest that certain pro-apoptotic proteins may also contribute to apoptosis by a mechanism independent of binding pro-survival proteins. ..
  10. Woollatt E, Pine K, Shine J, Sutherland G, Iismaa T. Human Sec63 endoplasmic reticulum membrane protein, map position 6q21. Chromosome Res. 1999;7:77 pubmed
  11. Smith F, Hawkesford M, Prosser I, Clarkson D. Isolation of a cDNA from Saccharomyces cerevisiae that encodes a high affinity sulphate transporter at the plasma membrane. Mol Gen Genet. 1995;247:709-15 pubmed
    ..We conclude that the SUL1 cDNA encodes a S. cerevisiae high affinity sulphate transporter that is responsible for the transfer of sulphate across the plasma membrane from the external medium. ..