Experts and Doctors on ralstonia solanacearum in France


Locale: France
Topic: ralstonia solanacearum

Top Publications

  1. Peeters N, Carrère S, Anisimova M, Plener L, Cazalé A, Genin S. Repertoire, unified nomenclature and evolution of the Type III effector gene set in the Ralstonia solanacearum species complex. BMC Genomics. 2013;14:859 pubmed publisher
  2. Poueymiro M, Genin S. Secreted proteins from Ralstonia solanacearum: a hundred tricks to kill a plant. Curr Opin Microbiol. 2009;12:44-52 pubmed publisher
    ..solanacearum Type III effectors subvert host cellular pathways, either by mimicking action of key host proteins or by inducing their subcellular relocalization. ..
  3. Lonjon F, Turner M, Henry C, Rengel D, Lohou D, van de Kerkhove Q, et al. Comparative Secretome Analysis of Ralstonia solanacearum Type 3 Secretion-Associated Mutants Reveals a Fine Control of Effector Delivery, Essential for Bacterial Pathogenicity. Mol Cell Proteomics. 2016;15:598-613 pubmed publisher
    ..HpaB was required for bacterial pathogenicity on multiple hosts whereas HpaG was found to be specifically required for full R. solanacearum pathogenicity on the legume plant Medicago truncatula. ..
  4. Meyer D, Cunnac S, Guéneron M, Declercq C, Van Gijsegem F, Lauber E, et al. PopF1 and PopF2, two proteins secreted by the type III protein secretion system of Ralstonia solanacearum, are translocators belonging to the HrpF/NopX family. J Bacteriol. 2006;188:4903-17 pubmed
    ..However, although one of these proteins is clearly related to PopF1 and PopF2, the other seems to be different and related to NopX proteins, thus showing that translocators might be variable in R. solanacearum. ..
  5. Turner M, Jauneau A, Genin S, Tavella M, Vailleau F, Gentzbittel L, et al. Dissection of bacterial Wilt on Medicago truncatula revealed two type III secretion system effectors acting on root infection process and disease development. Plant Physiol. 2009;150:1713-22 pubmed publisher
    ..However, later disease symptoms were reduced in the gala7 mutant, indicating a key role in later stages of infection. ..
  6. Godiard L, Sauviac L, Torii K, Grenon O, Mangin B, Grimsley N, et al. ERECTA, an LRR receptor-like kinase protein controlling development pleiotropically affects resistance to bacterial wilt. Plant J. 2003;36:353-65 pubmed
    ..solanacearum as indicated by reduced wilt symptoms and impaired bacterial growth, suggesting unexpected cross-talk between resistance and developmental pathways. ..
  7. Guy E, Lautier M, Chabannes M, Roux B, Lauber E, Arlat M, et al. xopAC-triggered immunity against Xanthomonas depends on Arabidopsis receptor-like cytoplasmic kinase genes PBL2 and RIPK. PLoS ONE. 2013;8:e73469 pubmed publisher
    ..Within this subfamily, PBL2 and RIPK RLCK genes but not BIK1 are important for xopAC-specified effector-triggered immunity and Arabidopsis resistance to Xcc. ..
  8. Genin S, Denny T. Pathogenomics of the Ralstonia solanacearum species complex. Annu Rev Phytopathol. 2012;50:67-89 pubmed publisher
  9. Remigi P, Anisimova M, Guidot A, Genin S, Peeters N. Functional diversification of the GALA type III effector family contributes to Ralstonia solanacearum adaptation on different plant hosts. New Phytol. 2011;192:976-87 pubmed publisher
    ..We conclude that functional divergence of the GALA family likely accounts for its remarkable conservation during R. solanacearum evolution and could contribute to R. solanacearum's adaptation on several host plants...

More Information


  1. Danchin E, Rosso M, Vieira P, de Almeida Engler J, Coutinho P, Henrissat B, et al. Multiple lateral gene transfers and duplications have promoted plant parasitism ability in nematodes. Proc Natl Acad Sci U S A. 2010;107:17651-6 pubmed publisher
    ..Multiple functional acquisitions of exogenous genes that provide selective advantage were probably crucial for the emergence and proficiency of plant parasitism in nematodes...
  2. Genin S. Molecular traits controlling host range and adaptation to plants in Ralstonia solanacearum. New Phytol. 2010;187:920-8 pubmed publisher
    ..These hrpG-dependent genes control major steps during the interaction with plant cells, and probably determine the ecological behaviour of the microorganism, being required for the establishment of pathogenesis or mutualism...
  3. Genin S, Boucher C. Lessons learned from the genome analysis of ralstonia solanacearum. Annu Rev Phytopathol. 2004;42:107-34 pubmed
    ..It also provided insights into possible mechanisms contributing to the rapid adaptation of the bacterium to its environment in general and to its interaction with plants in particular...
  4. Cunnac S, Occhialini A, Barberis P, Boucher C, Genin S. Inventory and functional analysis of the large Hrp regulon in Ralstonia solanacearum: identification of novel effector proteins translocated to plant host cells through the type III secretion system. Mol Microbiol. 2004;53:115-28 pubmed publisher
    ..solanacearum virulence...
  5. Delaspre F, Nieto Penalver C, Saurel O, Kiefer P, Gras E, Milon A, et al. The Ralstonia solanacearum pathogenicity regulator HrpB induces 3-hydroxy-oxindole synthesis. Proc Natl Acad Sci U S A. 2007;104:15870-5 pubmed
    ..The failure to detect induction by HDF of the described endogenous quorum-sensing circuits of the pathogen points to a role in interfering with cell-cell signaling of rivalling bacteria. ..
  6. Wicker E, Grassart L, Coranson Beaudu R, Mian D, Guilbaud C, Fegan M, et al. Ralstonia solanacearum strains from Martinique (French West Indies) exhibiting a new pathogenic potential. Appl Environ Microbiol. 2007;73:6790-801 pubmed
    ..Phylotype II/4NPB constitutes a new pathogenic variant of R. solanacearum that has recently appeared in Martinique and may be latently prevalent throughout Caribbean and Central/South America...
  7. Valls M, Genin S, Boucher C. Integrated regulation of the type III secretion system and other virulence determinants in Ralstonia solanacearum. PLoS Pathog. 2006;2:e82 pubmed
  8. Lavie M, Seunes B, Prior P, Boucher C. Distribution and sequence analysis of a family of type ill-dependent effectors correlate with the phylogeny of Ralstonia solanacearum strains. Mol Plant Microbe Interact. 2004;17:931-40 pubmed
    ..The implications of these observations in terms of bacterial evolution, gene acquisition, and horizontal gene transfers are discussed...
  9. Bernoux M, Timmers T, Jauneau A, Briere C, de Wit P, Marco Y, et al. RD19, an Arabidopsis cysteine protease required for RRS1-R-mediated resistance, is relocalized to the nucleus by the Ralstonia solanacearum PopP2 effector. Plant Cell. 2008;20:2252-64 pubmed publisher
    ..We propose that RD19 associates with PopP2 to form a nuclear complex that is required for activation of the RRS1-R-mediated resistance response...
  10. Poueymiro M, Cunnac S, Barberis P, Deslandes L, Peeters N, Cazale Noel A, et al. Two type III secretion system effectors from Ralstonia solanacearum GMI1000 determine host-range specificity on tobacco. Mol Plant Microbe Interact. 2009;22:538-50 pubmed publisher
    ..benthamiana. avrA appears to be the target of various DNA insertions or mobile elements that probably allow R. solanacearum to evade the recognition and defense responses of tobacco...
  11. Remenant B, Coupat Goutaland B, Guidot A, Cellier G, Wicker E, Allen C, et al. Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence. BMC Genomics. 2010;11:379 pubmed publisher
    ..The data are still too fragmentary to link genomic classification and phenotypes, but these new genome sequences identify a pan-genome more representative of the diversity in the R. solanancearum species complex. ..
  12. Cellier G, Prior P. Deciphering phenotypic diversity of Ralstonia solanacearum strains pathogenic to potato. Phytopathology. 2010;100:1250-61 pubmed publisher
    ..solanacearum species complex. ..
  13. Vailleau F, Sartorel E, Jardinaud M, Chardon F, Genin S, Huguet T, et al. Characterization of the interaction between the bacterial wilt pathogen Ralstonia solanacearum and the model legume plant Medicago truncatula. Mol Plant Microbe Interact. 2007;20:159-67 pubmed
    ..The results indicate that the root pathosystem for M. truncatula will provide useful traits for molecular analyses of disease and resistance in this model plant species. ..
  14. Angot A, Peeters N, Lechner E, Vailleau F, Baud C, Gentzbittel L, et al. Ralstonia solanacearum requires F-box-like domain-containing type III effectors to promote disease on several host plants. Proc Natl Acad Sci U S A. 2006;103:14620-5 pubmed
  15. Tasset C, Bernoux M, Jauneau A, Pouzet C, Briere C, Kieffer Jacquinod S, et al. Autoacetylation of the Ralstonia solanacearum effector PopP2 targets a lysine residue essential for RRS1-R-mediated immunity in Arabidopsis. PLoS Pathog. 2010;6:e1001202 pubmed publisher
  16. Gonzalez A, Plener L, Restrepo S, Boucher C, Genin S. Detection and functional characterization of a large genomic deletion resulting in decreased pathogenicity in Ralstonia solanacearum race 3 biovar 2 strains. Environ Microbiol. 2011;13:3172-85 pubmed publisher
    ..In addition, this study indicated that three type III secretion system effectors or a type VI secretion system present within the 77 kb region have no or very minor contribution to pathogenicity...
  17. Racap J, Belbahri L, Engelhardt S, Lacombe B, Lee J, Lochman J, et al. Ca2+-dependent lipid binding and membrane integration of PopA, a harpin-like elicitor of the hypersensitive response in tobacco. Mol Microbiol. 2005;58:1406-20 pubmed publisher
    ..These characteristics suggest that PopA is part of a system that aims to attach the host cell plasma membrane and to allow molecules cross this barrier...
  18. Effantin G, Hamasaki R, Kawasaki T, Bacia M, Moriscot C, Weissenhorn W, et al. Cryo-electron microscopy three-dimensional structure of the jumbo phage ?RSL1 infecting the phytopathogen Ralstonia solanacearum. Structure. 2013;21:298-305 pubmed publisher
    ..Our structural analyses indicate that ?RSL1 is an unusual member of the Myoviridae that employs conserved protein machines related to different phages and bacteria. ..
  19. Cunnac S, Boucher C, Genin S. Characterization of the cis-acting regulatory element controlling HrpB-mediated activation of the type III secretion system and effector genes in Ralstonia solanacearum. J Bacteriol. 2004;186:2309-18 pubmed
    ..solanacearum strain GMI1000. Among the 114 genes identified, a subset of promoters was found to have a structural relationship with hrp promoters, thus providing a pool of candidate genes encoding TTSS effectors. ..
  20. Genin S, Brito B, Denny T, Boucher C. Control of the Ralstonia solanacearum Type III secretion system (Hrp) genes by the global virulence regulator PhcA. FEBS Lett. 2005;579:2077-81 pubmed publisher
    ..This control of hrp gene expression by PhcA is realized at the level of the HrpG regulatory protein...