Experts and Doctors on protozoan proteins in Germany

Summary

Locale: Germany
Topic: protozoan proteins

Top Publications

  1. Palfi Z, Lane W, Bindereif A. Biochemical and functional characterization of the cis-spliceosomal U1 small nuclear RNP from Trypanosoma brucei. Mol Biochem Parasitol. 2002;121:233-43 pubmed
    ..The 5' end of U1 snRNA in the U1 snRNP is accessible for and functional in specific recognition of the 5' splice site of the poly(A) polymerase intron. ..
  2. Gräf R, Euteneuer U, Ho T, Rehberg M. Regulated expression of the centrosomal protein DdCP224 affects microtubule dynamics and reveals mechanisms for the control of supernumerary centrosome number. Mol Biol Cell. 2003;14:4067-74 pubmed
  3. Lin S, Gross U, Bohne W. Two internal type II NADH dehydrogenases of Toxoplasma gondii are both required for optimal tachyzoite growth. Mol Microbiol. 2011;82:209-21 pubmed publisher
    ..Together, our studies indicate that although TgNDH2-I and TgNDH2-II are individually non-essential, the expression of both internal isoforms is required to maintain the mitochondrial physiology in T. gondii tachyzoites. ..
  4. K ller J, M ller U, Schmid B, Missel A, Kruft V, Stuart K, et al. Trypanosoma brucei gBP21. An arginine-rich mitochondrial protein that binds to guide RNA with high affinity. J Biol Chem. 1997;272:3749-57 pubmed
    ..In contrast, the gRNA-gBP21 complex formation was sensitive to potassium and ammonium cations, thus indicating a contribution of ionic contacts to the binding...
  5. Schierwater B, Dellaporta S, DeSalle R. Is the evolution of Cnox-2 Hox/ParaHox genes "multicolored" and "polygenealogical?". Mol Phylogenet Evol. 2002;24:374-8 pubmed
    ..The existing data on possible gene functions also reveal a quite heterogeneous picture. It seems conceivable that part of the "multicolored" picture relates to a "polygenealogical" origin of the Cnox-2 gene. ..
  6. Rehberg M, Kleylein Sohn J, Faix J, Ho T, Schulz I, Gräf R. Dictyostelium LIS1 is a centrosomal protein required for microtubule/cell cortex interactions, nucleus/centrosome linkage, and actin dynamics. Mol Biol Cell. 2005;16:2759-71 pubmed
  7. Ceylan S, Seidel V, Ziebart N, Berndt C, Dirdjaja N, Krauth Siegel R. The dithiol glutaredoxins of african trypanosomes have distinct roles and are closely linked to the unique trypanothione metabolism. J Biol Chem. 2010;285:35224-37 pubmed publisher
    ..Grx1 and, less efficiently, also Grx2 catalyze the reduction of GSSG by trypanothione. Thus, the Grxs play exclusive roles in the trypanothione-based thiol redox metabolism of African trypanosomes...
  8. Maercker C, Lipps H. A macronuclear DNA molecule from the hypotrichous ciliate Stylonychia lemnae encoding a t-complex polypeptide 1-like protein. Gene. 1994;141:147-8 pubmed
    ..A macronuclear DNA molecule from Stylonychia lemnae with a size of 1891 nucleotides was cloned and sequenced. The 507-amino-acid computer-predicted sequence shares 41.9% identity with the mouse t-complex polypeptide 1 (TCP1)...
  9. Aebischer T, Harbecke D, Ilg T. Proteophosphoglycan, a major secreted product of intracellular Leishmania mexicana amastigotes, is a poor B-cell antigen and does not elicit a specific conventional CD4+ T-cell response. Infect Immun. 1999;67:5379-85 pubmed
    ..The complex glycan chains of aPPG, which exhibit important biological functions for the parasite, may therefore also have evolved to evade detection by the immune system of the host organism. ..

More Information

Publications131 found, 100 shown here

  1. Erdmann M, Scholz A, Melzer I, Schmetz C, Wiese M. Interacting protein kinases involved in the regulation of flagellar length. Mol Biol Cell. 2006;17:2035-45 pubmed
    ..This is the first time that two interacting components of a signaling cascade have been described in the genus Leishmania. Moreover, we set the stage for the analysis of reversible phosphorylation in flagellar morphogenesis...
  2. Ferreira da Silva M, Barbosa H, Gross U, Lüder C. Stress-related and spontaneous stage differentiation of Toxoplasma gondii. Mol Biosyst. 2008;4:824-34 pubmed publisher
    ..Together, these results strongly indicate that the complex cellular environment, besides exogenous stress factors, may govern the developmental differentiation of T. gondii. ..
  3. Pretzel J, Gehr M, Eisenkolb M, Wang L, Fritz Wolf K, Rahlfs S, et al. Characterization and redox regulation of Plasmodium falciparum methionine adenosyltransferase. J Biochem. 2016;160:355-367 pubmed
    ..This phenomenon connects cellular S-adenosylmethionine synthesis to the redox state of PfalMAT and therefore to the cellular redox homeostasis. ..
  4. Shahi S, Krauth Siegel R, Clayton C. Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei. Mol Microbiol. 2002;43:1129-38 pubmed
    ..Overexpression of TbMRPE had little effect on susceptibility to melarsoprol but did give two- to threefold resistance to suramin...
  5. Kunfermann A, Lienau C, Illarionov B, Held J, Grawert T, Behrendt C, et al. IspC as target for antiinfective drug discovery: synthesis, enantiomeric separation, and structural biology of fosmidomycin thia isosters. J Med Chem. 2013;56:8151-62 pubmed publisher
    ..Notably, IspC displays a high level of enantioselectivity for an ?-substituted fosmidomycin derivative. ..
  6. Naumann B, Busch A, Allmer J, Ostendorf E, Zeller M, Kirchhoff H, et al. Comparative quantitative proteomics to investigate the remodeling of bioenergetic pathways under iron deficiency in Chlamydomonas reinhardtii. Proteomics. 2007;7:3964-79 pubmed
  7. Stocker S, Hiery M, Marriott G. Phototactic migration of Dictyostelium cells is linked to a new type of gelsolin-related protein. Mol Biol Cell. 1999;10:161-78 pubmed
    ..We also present evidence for further representatives of the GRP125 type in Dictyostelium, as well as in heterologous cells from lower to higher eukaryotes. ..
  8. Reiss M, Viebig N, Brecht S, Fourmaux M, Soete M, Di Cristina M, et al. Identification and characterization of an escorter for two secretory adhesins in Toxoplasma gondii. J Cell Biol. 2001;152:563-78 pubmed
    ..We hypothesize that during invasion, MIC6 along with adhesins establishes a bridge between the host cell and the parasite. ..
  9. Irmer H, Clayton C. Degradation of the unstable EP1 mRNA in Trypanosoma brucei involves initial destruction of the 3'-untranslated region. Nucleic Acids Res. 2001;29:4707-15 pubmed
    ..The instability element may cause extremely rapid deadenylation, or it may be targeted by an endonuclease. ..
  10. Woehlbier U, Epp C, Hackett F, Blackman M, Bujard H. Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasion. Malar J. 2010;9:77 pubmed publisher
    ..The findings reported provide further support for the development of vaccines based on MSP-1/6/7 and AMA-1, which would possibly include a combination of these antigens. ..
  11. Sessler N, Krug K, Nordheim A, Mordmüller B, Macek B. Analysis of the Plasmodium falciparum proteasome using Blue Native PAGE and label-free quantitative mass spectrometry. Amino Acids. 2012;43:1119-29 pubmed publisher
    ..This study shows that BN PAGE in combination with label-free quantification and PCP is applicable to the analysis of multiprotein complexes directly from complex protein mixtures. ..
  12. Denninger V, Figarella K, Schönfeld C, Brems S, Busold C, Lang F, et al. Troglitazone induces differentiation in Trypanosoma brucei. Exp Cell Res. 2007;313:1805-19 pubmed
    ..To further investigate the mechanisms responsible for these changes, microarray analyses were performed, showing an upregulation of expression site associated gene 8 (ESAG8), a potential differentiation regulator. ..
  13. Petry F, Jakobi V, Wagner S, Tessema T, Thiel S, Loos M. Binding and activation of human and mouse complement by Cryptosporidium parvum (Apicomplexa) and susceptibility of C1q- and MBL-deficient mice to infection. Mol Immunol. 2008;45:3392-400 pubmed publisher
    ..The contribution of the complement system and the lectin pathway in particular to the host defence against cryptosporidiosis may become apparent in situations of immunodeficiency such as HIV infections or in early childhood. ..
  14. Röhrig U, Gerisch G, Morozova L, Schleicher M, Wegner A. Coactosin interferes with the capping of actin filaments. FEBS Lett. 1995;374:284-6 pubmed
  15. Schirenbeck A, Arasada R, Bretschneider T, Stradal T, Schleicher M, Faix J. The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation. Proc Natl Acad Sci U S A. 2006;103:7694-9 pubmed publisher
    ..Our data suggest that DdVASP is complexed with dDia2 in filopodial tips and support formin-mediated filament elongation by bundling nascent actin filaments...
  16. Herrmann D, Pantchev N, Vrhovec M, Barutzki D, Wilking H, Frohlich A, et al. Atypical Toxoplasma gondii genotypes identified in oocysts shed by cats in Germany. Int J Parasitol. 2010;40:285-92 pubmed publisher
    ..To our knowledge this is the first description of the presence of T. gondii genotypes different from the clonal Types I, II and III in the faeces of naturally infected cats. ..
  17. Brenndörfer M, Boshart M. Selection of reference genes for mRNA quantification in Trypanosoma brucei. Mol Biochem Parasitol. 2010;172:52-5 pubmed publisher
    ..For comparison of other conditions, the ranking algorithm is recommended to verify a reliable and valid normalization that is instrumental to quantitative analysis of gene expression. ..
  18. Pinchai N, Lee B, Holler E. Stage specific expression of poly(malic acid)-affiliated genes in the life cycle of Physarum polycephalum. Spherulin 3b and polymalatase. FEBS J. 2006;273:1046-55 pubmed
    ..Quantitative PCR then revealed low levels of mRNA in amoebae, high levels in plasmodia, and also low levels in spherules, in agreement with the expression under transcriptional regulation in these cells. ..
  19. Preusser C, Palfi Z, Bindereif A. Special Sm core complex functions in assembly of the U2 small nuclear ribonucleoprotein of Trypanosoma brucei. Eukaryot Cell. 2009;8:1228-34 pubmed publisher
    ..Together they form a high-affinity, U2-specific binding complex. This trypanosome-specific assembly differs from the mammalian system and provides a functional role for the Sm core variation found in the trypanosomal U2 snRNP. ..
  20. Tung S, Unal C, Ley A, Peña C, Tunggal B, Noegel A, et al. Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila. Cell Microbiol. 2010;12:765-80 pubmed publisher
    ..We conclude that ATG9 and hence macroautophagy has a protective role during pathogen infection. ..
  21. Zimorski V, Major P, Hoffmann K, Brás X, Martin W, Gould S. The N-terminal sequences of four major hydrogenosomal proteins are not essential for import into hydrogenosomes of Trichomonas vaginalis. J Eukaryot Microbiol. 2013;60:89-97 pubmed publisher
  22. Schwede A, Ellis L, Luther J, Carrington M, Stoecklin G, Clayton C. A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells. Nucleic Acids Res. 2008;36:3374-88 pubmed publisher
    ..In both species, depletion of Caf1 homologues inhibited deadenylation of bulk RNA and resulted in an increase in average poly(A) tail length...
  23. Singh A, Minia I, Droll D, Fadda A, Clayton C, Erben E. Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks. Nucleic Acids Res. 2014;42:4652-68 pubmed publisher
    ..Recruitment of MKT1-containing regulatory complexes to mRNAs via sequence-specific mRNA-binding proteins could thus control several different post-transcriptional regulons. ..
  24. Jenne N, Rauchenberger R, Hacker U, Kast T, Maniak M. Targeted gene disruption reveals a role for vacuolin B in the late endocytic pathway and exocytosis. J Cell Sci. 1998;111 ( Pt 1):61-70 pubmed
    ..Furthermore, in the mutants post-lysosomal vacuoles are dramatically increased in size and accumulate endocytic marker, suggesting a role for vacuolin B in targeting the vacuole for exocytosis. ..
  25. Winckler T, Trautwein C, Tschepke C, Neuhauser C, Zündorf I, Beck P, et al. Gene function analysis by amber stop codon suppression: CMBF is a nuclear protein that supports growth and development of Dictyostelium amoebae. J Mol Biol. 2001;305:703-14 pubmed
    ..Our results demonstrate that amber stop codon suppression may be a useful strategy to stably underexpress proteins whose coding genes cannot be successfully disrupted by homologous recombination. ..
  26. Huttenlauch I, Stick R. Occurrence of articulins and epiplasmins in protists. J Eukaryot Microbiol. 2003;50:15-8 pubmed
    ..Moreover, we present evidence that epiplasmins and articulins represent two distinct classes of cytoskeletal proteins. ..
  27. Na J, Tunggal B, Eichinger L. STATc is a key regulator of the transcriptional response to hyperosmotic shock. BMC Genomics. 2007;8:123 pubmed
    ..At least two signalling pathways are activated in Dictyostelium cells subjected to hypertonicity. STATc is responsible for the transcriptional changes of one of them. ..
  28. Willmund F, Dorn K, Schulz Raffelt M, Schroda M. The chloroplast DnaJ homolog CDJ1 of Chlamydomonas reinhardtii is part of a multichaperone complex containing HSP70B, CGE1, and HSP90C. Plant Physiol. 2008;148:2070-82 pubmed publisher
    ..As HSP70B, CDJ1, and CGE1 are derived from the endosymbiont, whereas HSP90C is of eukaryotic origin, we observe in the chloroplast the interaction of two chaperone systems of distinct evolutionary origin...
  29. Chu T, Lingelbach K, Przyborski J. Genetic evidence strongly support an essential role for PfPV1 in intra-erythrocytic growth of P. falciparum. PLoS ONE. 2011;6:e18396 pubmed publisher
    ..Our data provide strong genetic evidence that PfPV1 is essential for survival of blood stage P. falciparum, and further highlight the importance of parasitophorous vacuole proteins in this part of the parasite's life cycle. ..
  30. Santos de Macedo C, Gerold P, Jung N, Azzouz N, Kimmel J, Schwarz R. Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues. Eur J Biochem. 2001;268:6221-8 pubmed
  31. Njuguna J, Nassar M, Hoerauf A, Kaiser A. Cloning, expression and functional activity of deoxyhypusine synthase from Plasmodium vivax. BMC Microbiol. 2006;6:91 pubmed
    ..vivax, on the basis of specific enzymatic activity, cross-reactivity with a polyclonal antibody against human DHS, and amino acid identity with DHS homologs from the rodent malaria parasite, P. yoelii, and human P. falciparum strains. ..
  32. Steiner T, Lamerz A, Hess P, Breithaupt C, Krapp S, Bourenkov G, et al. Open and closed structures of the UDP-glucose pyrophosphorylase from Leishmania major. J Biol Chem. 2007;282:13003-10 pubmed
    ..The presented structures together with mutagenesis analyses provide a basis for a detailed analysis of the catalytic mechanism and for the design of species-specific UGPase inhibitors. ..
  33. Deponte M, Rahlfs S, Becker K. Peroxiredoxin systems of protozoal parasites. Subcell Biochem. 2007;44:219-29 pubmed
  34. Schilde C, Schönemann B, Sehring I, Plattner H. Distinct subcellular localization of a group of synaptobrevin-like SNAREs in Paramecium tetraurelia and effects of silencing SNARE-specific chaperone NSF. Eukaryot Cell. 2010;9:288-305 pubmed publisher
    ..The distinct distributions of these SNAREs emphasize the considerable differentiation of membrane trafficking, particularly along the endo-/phagocytic pathway, in this protozoan...
  35. Fadda A, Färber V, Droll D, Clayton C. The roles of 3'-exoribonucleases and the exosome in trypanosome mRNA degradation. RNA. 2013;19:937-47 pubmed publisher
    ..Results suggested that the exosome is involved in the processing of trypanosome snoRNAs. There was no correlation between effects on half-lives and on mRNA abundance...
  36. Mejia P, Diez Silva M, Kamena F, Lu F, Fernandes S, Seeberger P, et al. Human C1-Inhibitor Suppresses Malaria Parasite Invasion and Cytoadhesion via Binding to Parasite Glycosylphosphatidylinositol and Host Cell Receptors. J Infect Dis. 2016;213:80-9 pubmed publisher
    ..This study reveals that C1INH is a potential therapeutic antimalarial molecule able to interfere with severe-disease etiology at multiple levels through specific interactions with both parasite PfGPIs and host cell receptors. ..
  37. Tjaden J, Haferkamp I, Boxma B, Tielens A, Huynen M, Hackstein J. A divergent ADP/ATP carrier in the hydrogenosomes of Trichomonas gallinae argues for an independent origin of these organelles. Mol Microbiol. 2004;51:1439-46 pubmed
    ..Thus, our data support the hypothesis that the various hydrogenosomes evolved repeatedly and independently...
  38. Luu V, Brems S, Hoheisel J, Burchmore R, Guilbride D, Clayton C. Functional analysis of Trypanosoma brucei PUF1. Mol Biochem Parasitol. 2006;150:340-9 pubmed
    ..Alternatively, PUF proteins may be needed in differentiating trypanosomes or in non-culturable life-cycle stages. ..
  39. Schebb N, Vielhaber T, Jousset A, Karst U. Development of a liquid chromatography-based screening methodology for proteolytic enzyme activity. J Chromatogr A. 2009;1216:4407-15 pubmed publisher
    ..The described methodology represents a tool for serine protease screening in complex mixtures by a fast ESI-MS/MS identification of active samples followed by the separation and isolation of active sample constituents in LC-BCD. ..
  40. Schwede A, Manful T, Jha B, Helbig C, Bercovich N, Stewart M, et al. The role of deadenylation in the degradation of unstable mRNAs in trypanosomes. Nucleic Acids Res. 2009;37:5511-28 pubmed publisher
    ..The results support a model in which trypanosome mRNAs can be degraded by at least two different, partially independent, cytoplasmic degradation pathways attacking both ends of the mRNA. ..
  41. Preußer C, Jaé N, Bindereif A. mRNA splicing in trypanosomes. Int J Med Microbiol. 2012;302:221-4 pubmed publisher
    ..Recent genome-wide studies demonstrated that alternative trans-splicing increases mRNA and protein diversity in these organisms. In this mini-review we give an overview of the current state of research on trans-splicing. ..
  42. Almasalmeh A, Krenc D, Wu B, Beitz E. Structural determinants of the hydrogen peroxide permeability of aquaporins. FEBS J. 2014;281:647-56 pubmed publisher
    ..Thus, generally, AQPs must be considered as putative players in situations of oxidative stress (e.g. in Plasmodium-infected red blood cells, immune cells, the cardiovascular system or cells expressing AQP8 in their mitochondria)...
  43. Gastens M, Fischer H. Toxoplasma gondii eukaryotic translation initiation factor 4A associated with tachyzoite virulence is down-regulated in the bradyzoite stage. Int J Parasitol. 2002;32:1225-34 pubmed
    ..The down-regulation of eIF4A in attenuated T. gondii parasites and in the bradyzoite stage implies a role in tuning of the homeostasis of protein biosynthesis. ..
  44. Strehle A, Schleicher M, Faix J. Trix, a novel Rac guanine-nucleotide exchange factor from Dictyostelium discoideum is an actin-binding protein and accumulates at endosomes. Eur J Cell Biol. 2006;85:1035-45 pubmed
    ..Our results suggest that Trix is specifically involved in a Rho GTPase-signaling pathway that is required for regulation of the actin cytoskeleton during exocytosis. ..
  45. Somesh B, Neffgen C, Iijima M, Devreotes P, Rivero F. Dictyostelium RacH regulates endocytic vesicular trafficking and is required for localization of vacuolin. Traffic. 2006;7:1194-212 pubmed
    ..Overexpression of mistargeted RacH mutants did not recapitulate the phenotypes of a strain overexpressing nonmutated RacH, indicating that the function of this protein is in great part related to its subcellular localization. ..
  46. Schlecker T, Schmidt A, Dirdjaja N, Voncken F, Clayton C, Krauth Siegel R. Substrate specificity, localization, and essential role of the glutathione peroxidase-type tryparedoxin peroxidases in Trypanosoma brucei. J Biol Chem. 2005;280:14385-94 pubmed
    ..Thus, the cellular functions of the glutathione peroxidase-type enzymes cannot be taken over by the 2 Cys-peroxiredoxins that also occur in the cytosol and mitochondrion of the parasite. ..
  47. Kaller M, F ldesi B, Nellen W. Localization and organization of protein factors involved in chromosome inheritance in Dictyostelium discoideum. Biol Chem. 2007;388:355-65 pubmed publisher
    ..In addition, it is associated with the centrosome throughout the cell cycle. The results indicate that, similar to Orc2 homologs from other organisms, it is required for different processes in chromosome inheritance...
  48. Külzer S, Gehde N, Przyborski J. Return to sender: use of Plasmodium ER retrieval sequences to study protein transport in the infected erythrocyte and predict putative ER protein families. Parasitol Res. 2009;104:1535-41 pubmed publisher
    ..Furthermore, using our knowledge of ER retrieval signals, we identify Plasmodium ER protein families and assign putative functions to them. ..
  49. Schwassmann H, Rexroth S, Seelert H, Dencher N. Metabolism controls dimerization of the chloroplast FoF1 ATP synthase in Chlamydomonas reinhardtii. FEBS Lett. 2007;581:1391-6 pubmed
    ..As compared to photoautotrophic growth, an increased assembly of ATP synthase dimers on the expense of preexisting monomers during photomixotrophic growth was observed, demonstrating a metabolic control of the dimerization process. ..
  50. Schulte T, Sharples F, Hiller R, Hofmann E. X-ray structure of the high-salt form of the peridinin-chlorophyll a-protein from the dinoflagellate Amphidinium carterae: modulation of the spectral properties of pigments by the protein environment. Biochemistry. 2009;48:4466-75 pubmed publisher
  51. Schulz I, Erle A, Gräf R, Krüger A, Lohmeier H, Putzler S, et al. Identification and cell cycle-dependent localization of nine novel, genuine centrosomal components in Dictyostelium discoideum. Cell Motil Cytoskeleton. 2009;66:915-28 pubmed publisher
  52. Rauchenberger R, Hacker U, Murphy J, Niewöhner J, Maniak M. Coronin and vacuolin identify consecutive stages of a late, actin-coated endocytic compartment in Dictyostelium. Curr Biol. 1997;7:215-8 pubmed
    ..Vacuoles were coated with filamentous actin along the entire post-lysosomal pathway, and the integrity of the actin coat was required for exocytosis. ..
  53. Flohe L, Hecht H, Steinert P. Glutathione and trypanothione in parasitic hydroperoxide metabolism. Free Radic Biol Med. 1999;27:966-84 pubmed
    ..By generally accepted criteria of target selection and feasibility considerations tryparedoxin and tryparedoxin peroxidase can at present be rated as the most appealing target structures for the development of antiparasitic drugs. ..
  54. Wurst M, Robles A, Po J, Luu V, Brems S, Marentije M, et al. An RNAi screen of the RRM-domain proteins of Trypanosoma brucei. Mol Biochem Parasitol. 2009;163:61-5 pubmed publisher
    ..The small, single-RRM protein TbRBP3 specifically associated with 10 mRNAs in trypanosome lysates, but RBP3 depletion did not affect the transcriptome...
  55. Westphal M, Jungbluth A, Heidecker M, Muhlbauer B, Heizer C, Schwartz J, et al. Microfilament dynamics during cell movement and chemotaxis monitored using a GFP-actin fusion protein. Curr Biol. 1997;7:176-83 pubmed
    ..Other clusters of GFP-actin might represent stores of monomeric actin in the form of complexes with actin-sequestering proteins. ..
  56. Bakheit M, Schnittger L, Salih D, Boguslawski K, Beyer D, Fadl M, et al. Application of the recombinant Theileria annulata surface protein in an indirect ELISA for the diagnosis of tropical theileriosis. Parasitol Res. 2004;92:299-302 pubmed
    ..Our test has proved its suitability for the diagnosis of tropical theileriosis and could be used in serological surveys to map out the prevalence of the disease or to monitor vaccination efficiencies in disease-free populations...
  57. Weide T, Bockau U, Rave A, Herrmann L, Hartmann M. A recombinase system facilitates cloning of expression cassettes in the ciliate Tetrahymena thermophila. BMC Microbiol. 2007;7:12 pubmed
    ..However, the AT-richness of the genome and an unusual codon usage cause problems in cloning and expression of the ciliate DNA. To overcome these technical hiatuses we developed a Cre-dependent recombinase system...
  58. Daunderer C, Gräf R. Molecular analysis of the cytosolic Dictyostelium gamma-tubulin complex. Eur J Cell Biol. 2002;81:175-84 pubmed
    ..Dictyostelium is thus the first organism investigated so far where the three proteins do not interact stably in the cytosol...
  59. Rivero F, Illenberger D, Somesh B, Dislich H, Adam N, Meyer A. Defects in cytokinesis, actin reorganization and the contractile vacuole in cells deficient in RhoGDI. EMBO J. 2002;21:4539-49 pubmed
    ..Our results indicate that GDI1 plays a central role in the regulation of signal transduction cascades mediated by Rho GTPases. ..
  60. Eszterbauer E, Kallert D, Grabner D, El Matbouli M. Differentially expressed parasite genes involved in host recognition and invasion of the triactinomyxon stage of Myxobolus cerebralis (Myxozoa). Parasitology. 2009;136:367-77 pubmed publisher
    ..cerebralis TAMs. ..
  61. Daunderer C, Schliwa M, Graf R. Dictyostelium centrin-related protein (DdCrp), the most divergent member of the centrin family, possesses only two EF hands and dissociates from the centrosome during mitosis. Eur J Cell Biol. 2001;80:621-30 pubmed
    ..The striking differences of DdCrp to all other centrins may be related to the distinct structure and duplication mode of the Dictyostelium centrosome. ..
  62. Martens H, Novotny J, Oberstrass J, Steck T, Postlethwait P, Nellen W. RNAi in Dictyostelium: the role of RNA-directed RNA polymerases and double-stranded RNase. Mol Biol Cell. 2002;13:445-53 pubmed
    ..Both RrpA and a target gene were required for production of detectable amounts of about 23mers, suggesting that target sequences are involved in about 23mer amplification. ..
  63. Lanzer M, Wickert H, Krohne G, Vincensini L, Braun Breton C. Maurer's clefts: a novel multi-functional organelle in the cytoplasm of Plasmodium falciparum-infected erythrocytes. Int J Parasitol. 2006;36:23-36 pubmed
    ..Here, we review our current knowledge of the ultrastructure of Maurer's clefts, their proteinaceous composition and their function in protein trafficking. ..
  64. Marko M, Prabhu Y, Muller R, Blau Wasser R, Schleicher M, Noegel A. The annexins of Dictyostelium. Eur J Cell Biol. 2006;85:1011-22 pubmed
  65. Tsiavaliaris G, Fujita Becker S, D rrwang U, Diensthuber R, Geeves M, Manstein D. Mechanism, regulation, and functional properties of Dictyostelium myosin-1B. J Biol Chem. 2008;283:4520-7 pubmed publisher
    ..In this respect, its motor properties appear to be more closely related to Dictyostelium myosin-2 and rabbit skeletal muscle myosin...
  66. Samereier M, Baumann O, Meyer I, Gr f R. Analysis of Dictyostelium TACC reveals differential interactions with CP224 and unusual dynamics of Dictyostelium microtubules. Cell Mol Life Sci. 2011;68:275-87 pubmed publisher
  67. Abass E, Bollig N, Reinhard K, Camara B, Mansour D, Visekruna A, et al. rKLO8, a novel Leishmania donovani - derived recombinant immunodominant protein for sensitive detection of visceral leishmaniasis in Sudan. PLoS Negl Trop Dis. 2013;7:e2322 pubmed publisher
    ..The aim of this study is to improve diagnosis of VL in East Africa by testing a new antigen from an autochthonous L. donovani strain in Sudan...
  68. Muller S, Windhof I, Maximov V, Jurkowski T, Jeltsch A, Förstner K, et al. Target recognition, RNA methylation activity and transcriptional regulation of the Dictyostelium discoideum Dnmt2-homologue (DnmA). Nucleic Acids Res. 2013;41:8615-27 pubmed publisher
    ..As expression levels and binding of DnmA to a target in vivo are apparently not necessarily accompanied by methylation, we propose an additional biological function of DnmA apart from methylation. ..
  69. Blusch J, Nellen W. Folate responsiveness during growth and development of Dictyostelium: separate but related pathways control chemotaxis and gene regulation. Mol Microbiol. 1994;11:331-5 pubmed
    ..Therefore we conclude that the pathways for chemotaxis and for gene regulation diverge downstream of a common receptor type...
  70. Rosinke B, Renner C, Mayr E, Jaenicke R, Holak T. Ca2+-loaded spherulin 3a from Physarum polycephalum adopts the prototype gamma-crystallin fold in aqueous solution. J Mol Biol. 1997;271:645-55 pubmed
    ..Since spherulin 3a has a structure corresponding to one domain of bovine gammaB(II)-crystallin, it represents a hypothetical ancestral gamma-crystallin precursor structure...
  71. Eichinger L, Bahler M, Dietz M, Eckerskorn C, Schleicher M. Characterization and cloning of a Dictyostelium Ste20-like protein kinase that phosphorylates the actin-binding protein severin. J Biol Chem. 1998;273:12952-9 pubmed
    ..The presence of a Ste20-like severin kinase in Dictyostelium suggests a direct signal transduction from the plasma membrane to the cytoskeleton by phosphorylation of actin-binding proteins. ..
  72. Hansen M, Kun J, Schultz J, Beitz E. A single, bi-functional aquaglyceroporin in blood-stage Plasmodium falciparum malaria parasites. J Biol Chem. 2002;277:4874-82 pubmed
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