Experts and Doctors on potassium in Germany


Locale: Germany
Topic: potassium

Top Publications

  1. Hoock C, Steinmetz J, Schmidt H. Caffeine-evoked contractures in single slow (tonic) muscle fibres of the frog (Rana temporaria and R. esculenta). Pflugers Arch. 1996;432:207-14 pubmed
    ..Possible reasons for the ineffectiveness of intracellular caffeine are discussed...
  2. de Wit C, Roos F, Bolz S, Kirchhoff S, Kruger O, Willecke K, et al. Impaired conduction of vasodilation along arterioles in connexin40-deficient mice. Circ Res. 2000;86:649-55 pubmed
    ..Our observations indicate that Cx40 is required for normal transmission of endothelium-dependent vasodilator responses and may underlie altered vasomotion patterns. ..
  3. Jung K, Veen M, Altendorf K. K+ and ionic strength directly influence the autophosphorylation activity of the putative turgor sensor KdpD of Escherichia coli. J Biol Chem. 2000;275:40142-7 pubmed
  4. Estevez R, Boettger T, Stein V, Birkenhäger R, Otto E, Hildebrandt F, et al. Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion. Nature. 2001;414:558-61 pubmed
    ..This work describes the first known beta-subunit for CLC chloride channels and reveals that heteromers formed by ClC-K and barttin are crucial for renal salt reabsorption and potassium recycling in the inner ear. ..
  5. Peters M, Jeck N, Reinalter S, Leonhardt A, Tönshoff B, Klaus G G, et al. Clinical presentation of genetically defined patients with hypokalemic salt-losing tubulopathies. Am J Med. 2002;112:183-90 pubmed
    ..The aim of this study was to characterize the clinical features associated with each mutation in a large cohort of genetically defined patients...
  6. Gedrange T, Mai R, Richter G, Wolf P, Lupp A, Harzer W. X-ray microanalysis of elements in the masticatory muscle after paresis of the right masseter. J Dent Res. 2005;84:1026-30 pubmed
    ..Botox((R)) has an indirect impact on ion concentrations, resulting in changes in muscle functional capacity and adaptive compensation of paretic muscle function by other muscles...
  7. Westphal Varghese B, Erren M, Westphal M, Van Aken H, Ertmer C, Lange M, et al. Processing of stored packed red blood cells using autotransfusion devices decreases potassium and microaggregates: a prospective, randomized, single-blinded in vitro study. Transfus Med. 2007;17:89-95 pubmed
    ..e. hyperkalaemia and microvascular obstruction secondary to free cell fragments. This approach could be especially useful in patients undergoing massive transfusion and/or suffering from renal failure. ..
  8. Bender K, Nasrollahzadeh P, Timpert M, Liu B, Pott L, Kienitz M. A role for RGS10 in beta-adrenergic modulation of G-protein-activated K+ (GIRK) channel current in rat atrial myocytes. J Physiol. 2008;586:2049-60 pubmed publisher
    ..Moreover, RGS10, via PKA-dependent phosphorylation, enables a crosstalk between beta-adrenergic and muscarinic cholinergic signalling. ..
  9. Ciuman R. Stria vascularis and vestibular dark cells: characterisation of main structures responsible for inner-ear homeostasis, and their pathophysiological relations. J Laryngol Otol. 2009;123:151-62 pubmed publisher
    ..Further research on the distinct function and regulation of these structures is necessary in order to develop future clinical interventions...

More Information

Publications168 found, 100 shown here

  1. Oberleithner H, Callies C, Kusche Vihrog K, Schillers H, Shahin V, Riethmuller C, et al. Potassium softens vascular endothelium and increases nitric oxide release. Proc Natl Acad Sci U S A. 2009;106:2829-34 pubmed publisher
    ..Such a mechanism would control endothelial deformability and nitric oxide release, and thus influence systemic blood pressure. ..
  2. Geiger D, Becker D, Vosloh D, Gambale F, Palme K, Rehers M, et al. Heteromeric AtKC1{middle dot}AKT1 channels in Arabidopsis roots facilitate growth under K+-limiting conditions. J Biol Chem. 2009;284:21288-95 pubmed publisher
    ..Taken together, these findings suggest an essential role of AtKC1-like subunits for root K(+) uptake and K(+) homeostasis when plants experience conditions of K(+) limitation. ..
  3. Rotte A, Pasham V, Bhandaru M, Eichenmüller M, Yang W, Qadri S, et al. Regulation of gastric acid secretion by PKB/Akt2. Cell Physiol Biochem. 2010;25:695-704 pubmed publisher
    ..In conclusion, Akt2 suppresses gastric acid secretion and contributes to or even accounts for the inhibition of gastric acid secretion by PI3K. ..
  4. Köhler B, Wegner L, Osipov V, Raschke K. Loading of nitrate into the xylem: apoplastic nitrate controls the voltage dependence of X-QUAC, the main anion conductance in xylem-parenchyma cells of barley roots. Plant J. 2002;30:133-42 pubmed
  5. Egorov A, Angelova P, Heinemann U, Muller W. Ca2+-independent muscarinic excitation of rat medial entorhinal cortex layer V neurons. Eur J Neurosci. 2003;18:3343-51 pubmed
    ..Thus, muscarinic depolarization of EC layer V neurons appears to be primarily mediated by Ca2+-independent activation of non-specific cation channels that conduct K+ about three times as well as Na+. ..
  6. Gerevich Z, Borvendeg S, Schroder W, Franke H, Wirkner K, Nörenberg W, et al. Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia. J Neurosci. 2004;24:797-807 pubmed
    ..Hence, P2Y receptor activation by ADP, which is generated by enzymatic degradation of ATP, may decrease the release of glutamate from DRG terminals in the spinal cord and thereby partly counterbalance the algogenic effect of ATP. ..
  7. Koegel H, Alzheimer C. Expression and biological significance of Ca2+-activated ion channels in human keratinocytes. FASEB J. 2001;15:145-154 pubmed
    ..hSK4 might thus play a role in linking changes in membrane potential to the biological fate of keratinocytes. ..
  8. Schliess F, Schafer C, vom Dahl S, Fischer R, Lordnejad M, Haussinger D. Expression and regulation of the Na(+)/K(+)/2Cl(-) cotransporter NKCC1 in rat liver and human HuH-7 hepatoma cells. Arch Biochem Biophys. 2002;401:187-97 pubmed
    ..This was antagonized by the compatible organic osmolytes betaine or taurine. The data suggest a role of NKCC1 in stellate cell transformation, hepatic volume regulation, and long-term adaption to dehydrating conditions. ..
  9. Grahammer F, Artunc F, Sandulache D, Rexhepaj R, Friedrich B, Risler T, et al. Renal function of gene-targeted mice lacking both SGK1 and SGK3. Am J Physiol Regul Integr Comp Physiol. 2006;290:R945-50 pubmed
    ..Additional lack of the isoform kinase does not substantially compound the phenotype for either property. ..
  10. Sandmann M, Skłodowski K, Gajdanowicz P, Michard E, Rocha M, Gomez Porras J, et al. The K (+) battery-regulating Arabidopsis K (+) channel AKT2 is under the control of multiple post-translational steps. Plant Signal Behav. 2011;6:558-62 pubmed
    ..Here, we discuss the existence of multiple post-translational modification steps that work in concert to convert AKT2 from an inward-rectifying into a non-rectifying K (+) channel. ..
  11. Neidhardt H, Berner Z, Freikowski D, Biswas A, Winter J, Chatterjee D, et al. Influences of groundwater extraction on the distribution of dissolved As in shallow aquifers of West Bengal, India. J Hazard Mater. 2013;262:941-50 pubmed publisher
    ..Presented outcomes contribute to the discussion of anthropogenic pumping influences that endanger the limited and yet arsenic-free groundwater resources of the BDP. ..
  12. Berenbrink M, Völkel S, Heisler N, Nikinmaa M. O(2)-dependent K(+) fluxes in trout red blood cells: the nature of O(2) sensing revealed by the O(2) affinity, cooperativity and pH dependence of transport. J Physiol. 2000;526 Pt 1:69-80 pubmed
    ..49). The results of this study are consistent with an O(2) sensing mechanism differing markedly in affinity and cooperativity of O(2) binding, as well as in pH sensitivity, from bulk Hb. ..
  13. Hoener M. Role played by sodium in activity-dependent secretion of neurotrophins - revisited. Eur J Neurosci. 2000;12:3096-106 pubmed
  14. Kribben A, Feldkamp T, Horbelt M, Lange B, Pietruck F, Herget Rosenthal S, et al. ATP protects, by way of receptor-mediated mechanisms, against hypoxia-induced injury in renal proximal tubules. J Lab Clin Med. 2003;141:67-73 pubmed
    ..The data indicate that the protective effect of ATP is mediated by P(2) receptors. ..
  15. Hirsch J, Skutta N, Schlatter E. Signaling and distribution of NPR-Bi, the human splice form of the natriuretic peptide receptor type B. Am J Physiol Renal Physiol. 2003;285:F370-4 pubmed
    ..Tyrosine phosphorylation might be the missing link in the signaling pathway of CNP/NPR-Bi. ..
  16. Lang P, Kaiser S, Myssina S, Birka C, Weinstock C, Northoff H, et al. Effect of Vibrio parahaemolyticus haemolysin on human erythrocytes. Cell Microbiol. 2004;6:391-400 pubmed
    ..In conclusion, haemolysin Kanagawa induces cation permeability and activates endogenous Gardos K+ channels. Consequences include breakdown of phosphatidylserine asymmetry, which depends at least partially on cellular loss of K+. ..
  17. Jeck N, Waldegger S, Lampert A, Boehmer C, Waldegger P, Lang P, et al. Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension. Hypertension. 2004;43:1175-81 pubmed
    ..In conclusion, the mutation ClC-Kb(T481S) of the renal epithelial Cl- channel ClC-Kb strongly activates ClC-Kb chloride channel function in vitro and may predispose to the development of essential hypertension in vivo. ..
  18. Sano T, Becker D, Ivashikina N, Wegner L, Zimmermann U, Roelfsema M, et al. Plant cells must pass a K+ threshold to re-enter the cell cycle. Plant J. 2007;50:401-13 pubmed publisher
    ..Based on these findings, turgor regulation through modulation of K(+) channel density in plant cell division and cell-cycle progression is discussed...
  19. Oberleithner H, Kusche Vihrog K, Schillers H. Endothelial cells as vascular salt sensors. Kidney Int. 2010;77:490-4 pubmed publisher
    ..This sensitivity may serve as a physiological feedback mechanism to regulate local blood flow. It may also have pathophysiological relevance when sodium/potassium homeostasis is disturbed. ..
  20. Streit A, Netter M, Kempf F, Walecki M, Rinné S, Bollepalli M, et al. A specific two-pore domain potassium channel blocker defines the structure of the TASK-1 open pore. J Biol Chem. 2011;286:13977-84 pubmed publisher
    ..Our experimental data were used to validate a K(2P) open-pore homology model of TASK-1, providing structural insights for future rational design of drugs targeting K(2P) channels. ..
  21. Mulkidjanian A, Bychkov A, Dibrova D, Galperin M, Koonin E. Open questions on the origin of life at anoxic geothermal fields. Orig Life Evol Biosph. 2012;42:507-16 pubmed publisher
  22. Pasham V, Rotte A, Yang W, Zelenak C, Bhandaru M, Foller M, et al. OSR1-sensitive regulation of Na+/H+ exchanger activity in dendritic cells. Am J Physiol Cell Physiol. 2012;303:C416-26 pubmed publisher
    ..In conclusion, partial OSR1 deficiency influences Na(+)/H(+) exchanger activity, ROS formation, and migration of dendritic cells. ..
  23. von Schrenck T, Ahrens M, De Weerth A, Bobrowski C, Wolf G, Jonas L, et al. CCKB/gastrin receptors mediate changes in sodium and potassium absorption in the isolated perfused rat kidney. Kidney Int. 2000;58:995-1003 pubmed
    ..These receptors mediate changes in renal potassium and sodium absorption. In addition, gastrin causes a decrease in perfusate flow, indicating that CCKB receptors might also modulate vascular resistance in the kidney. ..
  24. Sindic A, Velic A, Başoglu C, Hirsch J, Edemir B, Kuhn M, et al. Uroguanylin and guanylin regulate transport of mouse cortical collecting duct independent of guanylate cyclase C. Kidney Int. 2005;68:1008-17 pubmed
    ..The first pathway most likely leads to an activation of the basolateral K+-conductance while the latter probably results in decreased activity of ROMK channels in the luminal membrane. ..
  25. Rübenhagen R, Morbach S, Kramer R. The osmoreactive betaine carrier BetP from Corynebacterium glutamicum is a sensor for cytoplasmic K+. EMBO J. 2001;20:5412-20 pubmed
    ..The half-maximal activation of BetP in E.coli phospholipid liposomes was correlated to an internal concentration of 221 +/- 23 mM K+. ..
  26. Stichtenoth D, Marhauer V, Tsikas D, Gutzki F, Frolich J. Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. Kidney Int. 2005;68:2197-207 pubmed
    ..Finally, the previously demonstrated shift of the thromboxane-prostacyclin balance toward prothrombotic thromboxane by specific COX-2 inhibition is confirmed. ..
  27. Lerche C, Scherer C, Seebohm G, Derst C, Wei A, Busch A, et al. Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity. J Biol Chem. 2000;275:22395-400 pubmed
    ..This functional interaction between KCNQ5 and KCNQ3, a component of the M-channel, suggests that KCNQ5 may contribute to a diversity of heteromeric channels underlying native neuronal M-currents. ..
  28. Ziegler A. X-ray microprobe analysis of epithelial calcium transport. Cell Calcium. 2002;31:307-21 pubmed
    ..Organelles, probably the smooth endoplasmic reticulum, sequester Ca(2+) during intracellular Ca(2+)-transport. A role of mitochondria as a storage site for cuticular Ca is excluded...
  29. Wen S, Schwarz J, Niculescu D, Dinu C, Bauer C, Hirdes W, et al. Functional characterization of genetically labeled gonadotropes. Endocrinology. 2008;149:2701-11 pubmed publisher
    ..Our mouse model will also be able to direct expression of other Cre recombination-dependent reporter genes to gonadotropes and, therefore, represents a versatile new tool in the understanding of gonadotrope biology. ..
  30. Fromm M, Tykocinski M, Schulzke J, Hegel U, Bentzel C. pH dependence of protamine action on apical membrane permeability in Necturus gallbladder epithelium. Biochim Biophys Acta. 1990;1027:179-84 pubmed
    ..At a solution pH of 7.1, 6 microM protamine fulfills criteria of a selective tool for reversibly altering structure and function of the tight junction in Necturus gallbladder...
  31. Treuner Lange A, Kuhn A, D rre P. The kdp system of Clostridium acetobutylicum: cloning, sequencing, and transcriptional regulation in response to potassium concentration. J Bacteriol. 1997;179:4501-12 pubmed
    ..Except for the two small peptides, all gene products could be detected in in vitro transcription-translation experiments...
  32. Katz V, Fuchs A, Conrath U. Pretreatment with salicylic acid primes parsley cells for enhanced ion transport following elicitation. FEBS Lett. 2002;520:53-7 pubmed
  33. Mähs A, Steinhorst L, Han J, Shen L, Wang Y, Kudla J. The calcineurin B-like Ca2+ sensors CBL1 and CBL9 function in pollen germination and pollen tube growth in Arabidopsis. Mol Plant. 2013;6:1149-62 pubmed publisher
    ..Together, our data identify a crucial function for CBL1 and CBL9 in pollen germination and tube growth and suggest a model in which both proteins act at the plasma membrane through regulation of K(+) homeostasis. ..
  34. Vasilets L, Takeda K, Kawamura M, Schwarz W. Significance of the glutamic acid residues Glu334, Glu959, and Glu960 of the alpha subunits of Torpedo Na+, K+ pumps for transport activity and ouabain binding. Biochim Biophys Acta. 1998;1368:137-49 pubmed
    ..We conclude that none of the mutated glutamic acid residues is essential for cation coordination, but that GIu334, and in part also Glu960, seems to be involved in preserving the ouabain-resistant conformation of the enzyme. ..
  35. Kroslak T, Koch T, Kahl E, Hollt V. Human phosphatidylethanolamine-binding protein facilitates heterotrimeric G protein-dependent signaling. J Biol Chem. 2001;276:39772-8 pubmed
    ..These data suggest a novel function of hPBP in regulating G protein and G protein-coupled receptor signaling in vivo. ..
  36. Riedel T, Schmalzing G, Markwardt F. Influence of extracellular monovalent cations on pore and gating properties of P2X7 receptor-operated single-channel currents. Biophys J. 2007;93:846-58 pubmed
  37. Schneider J, Nicolay J, Foller M, Wieder T, Lang F. Suicidal erythrocyte death following cellular K+ loss. Cell Physiol Biochem. 2007;20:35-44 pubmed
  38. Trefz F, Constable P, Lorenz I. Effect of Intravenous Small-Volume Hypertonic Sodium Bicarbonate, Sodium Chloride, and Glucose Solutions in Decreasing Plasma Potassium Concentration in Hyperkalemic Neonatal Calves with Diarrhea. J Vet Intern Med. 2017;31:907-921 pubmed publisher
    ..Small-volume hypertonic NaHCO3 infusions appear to have clinical advantages for the rapid resuscitation of hyperkalemic diarrheic calves, compared to hypertonic NaCl or glucose solutions. ..
  39. Jung K, Hamann K, Revermann A. K+ stimulates specifically the autokinase activity of purified and reconstituted EnvZ of Escherichia coli. J Biol Chem. 2001;276:40896-902 pubmed
    ..Whether K(+) accumulation, which is one of the first responses of E. coli after an osmotic upshift, is related to the stimulation of the EnvZ autokinase activity in vivo is discussed. ..
  40. Shrestha M, Shrestha P, Frenzel P, Conrad R. Effect of nitrogen fertilization on methane oxidation, abundance, community structure, and gene expression of methanotrophs in the rice rhizosphere. ISME J. 2010;4:1545-56 pubmed publisher
  41. Stumpe S, Bakker E. Requirement of a large K+-uptake capacity and of extracytoplasmic protease activity for protamine resistance of Escherichia coli. Arch Microbiol. 1997;167:126-36 pubmed
    ..Cells that cannot take up K+ rapidly remain metabolically compromised to such an extent that extracytoplasmic protease activity is not induced, leading to a prolonged susceptibility of the cells to the toxic peptide. ..
  42. Grewer C, Watzke N, Wiessner M, Rauen T. Glutamate translocation of the neuronal glutamate transporter EAAC1 occurs within milliseconds. Proc Natl Acad Sci U S A. 2000;97:9706-11 pubmed
  43. Mambretti E, Kistner K, Mayer S, Massotte D, Kieffer B, Hoffmann C, et al. Functional and structural characterization of axonal opioid receptors as targets for analgesia. Mol Pain. 2016;12: pubmed publisher
    ..Hypertonic saline acutely decreases ligand-induced internalization of MOP and thereby might improve MOP function. Further studies should explore potential clinical applications of opioids together with enhancers for regional analgesia. ..
  44. Gedrange T, Kuhn U, Walter B, Harzer W, Bauer R. Effects of 28-day mechanical and chewing stress on content of bound and diffusible ions in muscles of mastication. Exp Toxicol Pathol. 2001;53:207-13 pubmed
    ..These are considered to be indicators of more efficient contraction. The changes in ion concentration are an important factor in muscle contraction. ..
  45. Johnsen U, Hansen T, Schonheit P. Comparative analysis of pyruvate kinases from the hyperthermophilic archaea Archaeoglobus fulgidus, Aeropyrum pernix, and Pyrobaculum aerophilum and the hyperthermophilic bacterium Thermotoga maritima: unusual regulatory properties in hyperthermophil. J Biol Chem. 2003;278:25417-27 pubmed publisher
    ..Phylogenetic analysis of PK sequences of all three domains indicates a distinct archaeal cluster that includes the PK from the hyperthermophilic bacterium T. maritima...
  46. Schleussinger E, Schmid R, Bakker E. New type of kdp region with a split sensor-kinase kdpD gene located within two divergent kdp operons from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius. Biochim Biophys Acta. 2006;1759:437-41 pubmed
  47. Fischer M, Reeh P, Sauer S. Proton-induced calcitonin gene-related peptide release from rat sciatic nerve axons, in vitro, involving TRPV1. Eur J Neurosci. 2003;18:803-10 pubmed
    ..Axonal sensitivity to and sensitization by protons may be a pathophysiological mechanism involved in certain peripheral neuropathies. ..
  48. Bramkamp M, Altendorf K. Single amino acid substitution in the putative transmembrane helix V in KdpB of the KdpFABC complex of Escherichia coli uncouples ATPase activity and ion transport. Biochemistry. 2005;44:8260-6 pubmed
  49. Neupärtl M, Meyer C, Woll I, Frohns F, Kang M, Van Etten J, et al. Chlorella viruses evoke a rapid release of K+ from host cells during the early phase of infection. Virology. 2008;372:340-8 pubmed
    ..Therefore, it is reasonable to postulate that loss of K(+) and associated water fluxes from the host lower the pressure barrier to aid ejection of DNA from the virus particles into the host...
  50. Muller W, Bittner K. Differential oxidative modulation of voltage-dependent K+ currents in rat hippocampal neurons. J Neurophysiol. 2002;87:2990-5 pubmed
  51. Schubert R, Krien U, Gagov H. Protons inhibit the BK(Ca) channel of rat small artery smooth muscle cells. J Vasc Res. 2001;38:30-8 pubmed
  52. Kuner R, Kohr G, Grunewald S, Eisenhardt G, Bach A, Kornau H. Role of heteromer formation in GABAB receptor function. Science. 1999;283:74-7 pubmed
    ..Thus, the interaction of these receptors appears to be crucial for important physiological effects of GABA and provides a mechanism in receptor signaling pathways that involve a heterotrimeric GTP-binding protein. ..
  53. Westfahl C, Wolf P, Kamphues J. Estimation of inevitable macro mineral losses in amazons (Amazona spp.) as basis for the calculation of maintenance requirement. Arch Anim Nutr. 2009;63:75-85 pubmed publisher
    ..4%), potassium (21.8%) and sodium (4.5%), whereas the calcium and phosphorus content in plasma stayed constant or did not show unidirectional changes in all animals...
  54. Doring F, Derst C, Wischmeyer E, Karschin C, Schneggenburger R, Daut J, et al. The epithelial inward rectifier channel Kir7.1 displays unusual K+ permeation properties. J Neurosci. 1998;18:8625-36 pubmed
    ..These findings support the important role of this site in the regulation of K+ permeability in Kir channels by extracellular cations. ..
  55. Bauer C, Falk T, Schwarz J. An endogenous inactivating inward-rectifying potassium current in oocytes of Xenopus laevis. Pflugers Arch. 1996;432:812-20 pubmed
    ..The oxidant chloramine-T blocked the inward-rectifying K+ current without slowing its inactivation. ..
  56. Spitzer M, Reeh P, Sauer S. Mechanisms of potassium- and capsaicin-induced axonal calcitonin gene-related peptide release: involvement of L- and T-type calcium channels and TRPV1 but not sodium channels. Neuroscience. 2008;151:836-42 pubmed publisher
    ..Action potential generation and propagation are not required for axonal release mechanisms. ..
  57. Poppe M, Reimertz C, Dussmann H, Krohn A, Luetjens C, Bockelmann D, et al. Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis. J Neurosci. 2001;21:4551-63 pubmed
  58. Vormann J, Worlitschek M, Goedecke T, Silver B. Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain. J Trace Elem Med Biol. 2001;15:179-83 pubmed
    ..The simple and safe addition of an alkaline multimineral preparate was able to reduce the pain symptoms in these patients with chronic low back pain. ..
  59. Kahlert S, Zündorf G, Reiser G. Detection of de- and hyperpolarization of mitochondria of cultured astrocytes and neurons by the cationic fluorescent dye rhodamine 123. J Neurosci Methods. 2008;171:87-92 pubmed publisher
    ..This enhancement is interpreted as an increase in mitochondrial potential above the control potential. Thus, this Rh123 method described here allows a cell type-specific determination of changes of mitochondrial polarization. ..
  60. Song P, Groos S, Riederer B, Feng Z, Krabbenhöft A, Smolka A, et al. KCNQ1 is the luminal K+ recycling channel during stimulation of gastric acid secretion. J Physiol. 2009;587:3955-65 pubmed publisher
    ..The study demonstrates that the KCNQ1 channel provides K(+) to the extracellular K(+) binding site of the H(+)/K(+)-ATPase during acid secretion, and no other gastric K(+) channel can substitute for this function. ..
  61. Schneck E, Schubert T, Konovalov O, Quinn B, Gutsmann T, Brandenburg K, et al. Quantitative determination of ion distributions in bacterial lipopolysaccharide membranes by grazing-incidence X-ray fluorescence. Proc Natl Acad Sci U S A. 2010;107:9147-51 pubmed publisher
    ..The experimental findings were compared to the results of Monte Carlo simulations based on a coarse-grained minimal model of LPS molecules and showed excellent agreement. ..
  62. Tholema N, Vor der Brüggen M, Maser P, Nakamura T, Schroeder J, Kobayashi H, et al. All four putative selectivity filter glycine residues in KtrB are essential for high affinity and selective K+ uptake by the KtrAB system from Vibrio alginolyticus. J Biol Chem. 2005;280:41146-54 pubmed
    ..They also indicate that the role of KtrA lies in conferring velocity and ion coupling to the Ktr complex...
  63. Geiger D, Becker D, Lacombe B, Hedrich R. Outer pore residues control the H(+) and K(+) sensitivity of the Arabidopsis potassium channel AKT3. Plant Cell. 2002;14:1859-68 pubmed
    ..Both properties, H(+) and K(+) sensitivity, allow the fine-tuning of the phloem channel and thus seem to represent important elements in the control of membrane potential and sugar loading. ..
  64. Haupt M, Bramkamp M, Heller M, Coles M, Deckers Hebestreit G, Herkenhoff Hesselmann B, et al. The holo-form of the nucleotide binding domain of the KdpFABC complex from Escherichia coli reveals a new binding mode. J Biol Chem. 2006;281:9641-9 pubmed
  65. Hänelt I, Löchte S, Sundermann L, Elbers K, Vor der Brüggen M, Bakker E. Gain of function mutations in membrane region M2C2 of KtrB open a gate controlling K+ transport by the KtrAB system from Vibrio alginolyticus. J Biol Chem. 2010;285:10318-27 pubmed publisher
    ..These data are interpreted to mean (i) that region M(2C2) forms a flexible gate controlling K(+) translocation at the cytoplasmic side of KtrB, and (ii) that M(2C2) is required for the interaction between KtrA and KtrB...
  66. Hänelt I, Wunnicke D, Müller Trimbusch M, Vor der Brüggen M, Kraus I, Bakker E, et al. Membrane region M2C2 in subunit KtrB of the K+ uptake system KtrAB from Vibrio alginolyticus forms a flexible gate controlling K+ flux: an electron paramagnetic resonance study. J Biol Chem. 2010;285:28210-9 pubmed publisher
    ..Based on distances determined between spin-labeled residues of double-labeled variants of KtrB in the presence and absence of K(+) ions, structural models of the open and closed conformations were developed. ..
  67. Eggert K, von Wirén N. Dynamics and partitioning of the ionome in seeds and germinating seedlings of winter oilseed rape. Metallomics. 2013;5:1316-25 pubmed publisher
    ..This study documents highly dynamic changes in the ionome of seed and seedling tissues and provides evidence for potentially limiting elements during early germination and seedling establishment in rapeseed. ..
  68. Czempinski K, Zimmermann S, Ehrhardt T, Müller Röber B. New structure and function in plant K+ channels: KCO1, an outward rectifier with a steep Ca2+ dependency. EMBO J. 1997;16:2565-75 pubmed
    ..The identification of KCO1 as the first plant K+ outward channel opens a new field of structure-function studies in plant ion channels. ..
  69. Jung K, Krabusch M, Altendorf K. Cs(+) induces the kdp operon of Escherichia coli by lowering the intracellular K(+) concentration. J Bacteriol. 2001;183:3800-3 pubmed
    ..Moreover, the results imply that the signal transduction cascade mediated by KdpD and KdpE is able to integrate multiple signals. ..
  70. Priebe L, Friedrich M, Benndorf K. Functional interaction between K(ATP) channels and the Na(+)-K(+) pump in metabolically inhibited heart cells of the guinea-pig. J Physiol. 1996;492 ( Pt 2):405-17 pubmed
  71. Schonfeld P, Schüttig R, Wojtczak L. Rapid release of Mg(2+) from liver mitochondria by nonesterified long-chain fatty acids in alkaline media. Arch Biochem Biophys. 2002;403:16-24 pubmed
    ..It is hypothesized that fatty acids activate an intrinsic Mg(2+)/H(+) exchanger that is related to, or identical with, the K(+)/H(+) exchanger. ..
  72. Peters B, Teubner P, Clausmeyer S, Puschner T, Maser Gluth C, Wrede H, et al. StAR expression and the long-term aldosterone response to high-potassium diet in Wistar-Kyoto and spontaneously hypertensive rats. Am J Physiol Endocrinol Metab. 2007;292:E16-23 pubmed
    ..This increase alone is not sufficient to increase aldosterone production in the presence of normal Cyp11b2 mRNA levels. ..
  73. Oehmichen M, Hennig R, Meissner C. Near-drowning and clinical laboratory changes. Leg Med (Tokyo). 2008;10:1-5 pubmed
  74. Palmer A, Chiesa V, Schmid A, Münch G, Grobbel B, Zimmermann P, et al. Tetrahydrochromenoimidazoles as potassium-competitive acid blockers (P-CABs): structure-activity relationship of their antisecretory properties and their affinity toward the hERG channel. J Med Chem. 2010;53:3645-74 pubmed publisher
    ..Several tetrahydrochromenoimidazoles were identified that possessed a comparable profile as the candidate 4. ..
  75. Heine R, Pika U, Lehmann Horn F. A novel SCN4A mutation causing myotonia aggravated by cold and potassium. Hum Mol Genet. 1993;2:1349-53 pubmed
    ..In addition, the close-by occurring substitution of valine for methionine at position 1592 known to cause hyperkalemic periodic paralysis was deduced for six families with the myotonic, non-dystrophic form of this disease...
  76. Schneider A, Smith R, Kautz A, Weisshart K, Grosse F, Nasheuer H. Primase activity of human DNA polymerase alpha-primase. Divalent cations stabilize the enzyme activity of the p48 subunit. J Biol Chem. 1998;273:21608-15 pubmed
    ..A complex of bacterially expressed primase and baculovirus-expressed p180 and p68 was assembled in vitro and shown to support replication of simian virus 40 DNA in a cell-free system. ..
  77. Burkhardt C, Zacharias M. Modelling ion binding to AA platform motifs in RNA: a continuum solvent study including conformational adaptation. Nucleic Acids Res. 2001;29:3910-8 pubmed
    ..The approach could be helpful to identify putative ion binding sites in nucleic acid structures determined at low resolution or with experimental methods that do not allow identification of ion binding sites. ..
  78. Specht H, Peterziel H, Bajohrs M, Gerdes H, Krieglstein K, Unsicker K. Transforming growth factor beta2 is released from PC12 cells via the regulated pathway of secretion. Mol Cell Neurosci. 2003;22:75-86 pubmed
    ..Our results indicate that a substantial portion of TGF-beta2 is secreted by the regulated secretory pathway in PC12 cells and hippocampal neurons. ..
  79. Roychowdhury S, Noack J, Engelmann M, Wolf G, Horn T. AMPA receptor-induced intracellular calcium response in the paraventricular nucleus is modulated by nitric oxide: calcium imaging in a hypothalamic organotypic cell culture model. Nitric Oxide. 2006;14:290-9 pubmed
    ..Taken together, these data suggest that AMPA mediates the glutamate-induced [Ca(2+)](i) rises within the PVN, where endogenous NO is able to modulate such glutamate signaling in OCC. ..
  80. Bachmann O, Juric M, Seidler U, Manns M, Yu H. Basolateral ion transporters involved in colonic epithelial electrolyte absorption, anion secretion and cellular homeostasis. Acta Physiol (Oxf). 2011;201:33-46 pubmed publisher
    ..Finally, disturbances of basolateral electrolyte transport during disease states such as mucosal inflammation will be reviewed. ..
  81. Burckhardt B, Lorenz J, Burckhardt G, Steffgen J. Interactions of benzylpenicillin and non-steroidal anti-inflammatory drugs with the sodium-dependent dicarboxylate transporter NaDC-3. Cell Physiol Biochem. 2004;14:415-24 pubmed
    ..The data show hitherto unknown effects of monovalent anionic drugs on a transporter for divalent di- and tricarboxylates. ..
  82. Zimmermann B, Plank C, Konrad M, Stöhr W, Gravou Apostolatou C, Rascher W, et al. Hydrochlorothiazide in CLDN16 mutation. Nephrol Dial Transplant. 2006;21:2127-32 pubmed
    ..However, the short-term efficacy of HCT to reduce hypercalciuria in FHHNC has not yet been demonstrated in a clinical trial...
  83. Callies C, Fels J, Liashkovich I, Kliche K, Jeggle P, Kusche Vihrog K, et al. Membrane potential depolarization decreases the stiffness of vascular endothelial cells. J Cell Sci. 2011;124:1936-42 pubmed publisher
    ..This depolarization-induced decrease in the stiffness of endothelial cells could play a role in flow-mediated nitric-oxide-dependent vasodilation. ..
  84. Kixm ller D, Strahl H, Wende A, Greie J. Archaeal transcriptional regulation of the prokaryotic KdpFABC complex mediating K(+) uptake in H. salinarum. Extremophiles. 2011;15:643-52 pubmed publisher
  85. Hirsch J, Meyer M, Mägert H, Forssmann W, Mollerup S, Herter P, et al. cGMP-dependent and -independent inhibition of a K+ conductance by natriuretic peptides: molecular and functional studies in human proximal tubule cells. J Am Soc Nephrol. 1999;10:472-80 pubmed
    ..These findings indicate that natriuretic peptides regulate electrogenic transport processes via cGMP-dependent and -independent pathways that influence the Vm of IHKE-1 cells. ..
  86. Bertrand J, Altendorf K, Bramkamp M. Amino acid substitutions in putative selectivity filter regions III and IV in KdpA alter ion selectivity of the KdpFABC complex from Escherichia coli. J Bacteriol. 2004;186:5519-22 pubmed
    ..Replacement of the glycine residues in KdpA at positions 345 and 470, members of putative selectivity filter regions III and IV, alters the ion selectivity of the KdpFABC complex. ..
  87. Meier S, Kovalchuk Y, Rose C. Properties of the new fluorescent Na+ indicator CoroNa Green: comparison with SBFI and confocal Na+ imaging. J Neurosci Methods. 2006;155:251-9 pubmed
    ..In conclusion, CoroNa may prove to be a valuable tool for confocal Na+ imaging in fine cellular processes. ..
  88. Linz D, Schotten U, Neuberger H, Bohm M, Wirth K. Combined blockade of early and late activated atrial potassium currents suppresses atrial fibrillation in a pig model of obstructive apnea. Heart Rhythm. 2011;8:1933-9 pubmed publisher
    ..Neither amiodarone nor blockade of I(Kr) or I(Kur)/I(to) attenuated NTP-induced AERP shortening. However, the combined blockade of I(Kur)/I(to) and I(Kr) suppressed NTP-induced AERP shortening. ..
  89. Voelkner P, Puppe W, Altendorf K. Characterization of the KdpD protein, the sensor kinase of the K(+)-translocating Kdp system of Escherichia coli. Eur J Biochem. 1993;217:1019-26 pubmed
    ..Furthermore, replacement of the conserved histidine (His673), the predicted phosphorylation site in KdpD, by glutamine revealed that phosphorylation of KdpD was no longer possible. ..
  90. Gassel M, Möllenkamp T, Puppe W, Altendorf K. The KdpF subunit is part of the K(+)-translocating Kdp complex of Escherichia coli and is responsible for stabilization of the complex in vitro. J Biol Chem. 1999;274:37901-7 pubmed
    ..Although KdpF is not essential for the function of the Kdp complex in vivo, it is part of the complex and functions as a stabilizing element in vitro. The corresponding operon should now be referred to as kdpFABC. ..
  91. Karle C, Gehrig T, Wodopia R, Höschele S, Kreye V, Katus H, et al. Hypoxia-induced inhibition of whole cell membrane currents and ion transport of A549 cells. Am J Physiol Lung Cell Mol Physiol. 2004;286:L1154-60 pubmed
    ..It appears, therefore, that a hypoxia-induced change in membrane conductance and membrane potential might be a link between hypoxia and alveolar ion transport inhibition. ..
  92. Heermann R, Jung K. The complexity of the 'simple' two-component system KdpD/KdpE in Escherichia coli. FEMS Microbiol Lett. 2010;304:97-106 pubmed publisher
    ..Here, we will discuss the complexity of a 'simple' two-component system and its interconnectivity with metabolism and the general stress response. ..