Experts and Doctors on platelet activation in France


Locale: France
Topic: platelet activation

Top Publications

  1. Mouthon M, Gaugler M, Van der Meeren A, Vandamme M, Gourmelon P, Wagemaker G. Single administration of thrombopoietin to lethally irradiated mice prevents infectious and thrombotic events leading to mortality. Exp Hematol. 2001;29:30-40 pubmed
  2. Arnaud J, Bost M, Vitoux D, Labarere J, Galan P, Faure H, et al. Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites. J Am Coll Nutr. 2007;26:405-11 pubmed
    ..These results support the hypothesis that a low-dose multi-antioxidant supplementation may contributes to a reduction in platelet activation which is beneficial for cardiovascular function. ..
  3. Villeneuve J, Block A, Le Bousse Kerdiles M, Lepreux S, Nurden P, Ripoche J, et al. Tissue inhibitors of matrix metalloproteinases in platelets and megakaryocytes: a novel organization for these secreted proteins. Exp Hematol. 2009;37:849-56 pubmed publisher
    ..TIMPs are synthesized and organized in MKs and platelets independently of other secreted proteins present in alpha-granule pools. ..
  4. Alvarez Guerra M, Hernandez M, Escolar G, Chiavaroli C, Garay R, Hannaert P. The hemostatic agent ethamsylate enhances P-selectin membrane expression in human platelets and cultured endothelial cells. Thromb Res. 2002;107:329-35 pubmed
    ..These results support the view that ethamsylate acts on the first step of hemostasis, by improving platelet adhesiveness and restoring capillary resistance. ..
  5. Djaafri I, Maurice P, Labas V, Vinh J, Lemesle M, Arbeille B, et al. Platelet type III collagen binding protein (TIIICBP) presents high biochemical and functional similarities with kindlin-3. Biochimie. 2012;94:416-26 pubmed publisher
  6. Lhermusier T, Chap H, Payrastre B. Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome. J Thromb Haemost. 2011;9:1883-91 pubmed publisher
  7. Loyau S, Dumont B, Ollivier V, Boulaftali Y, Feldman L, Ajzenberg N, et al. Platelet glycoprotein VI dimerization, an active process inducing receptor competence, is an indicator of platelet reactivity. Arterioscler Thromb Vasc Biol. 2012;32:778-85 pubmed publisher
    ..GPVI dimers could represent a new marker to analyze platelet reactivity. ..
  8. Berrou E, Adam F, Lebret M, Planche V, Fergelot P, Issertial O, et al. Gain-of-Function Mutation in Filamin A Potentiates Platelet Integrin ?IIb?3 Activation. Arterioscler Thromb Vasc Biol. 2017;37:1087-1097 pubmed publisher
  9. Pedrono F, Cheminade C, Legrand A. Natural 1-O-alkylglycerols reduce platelet-activating factor-induced release of [3H]-serotonin in rabbit platelets. Prostaglandins Leukot Essent Fatty Acids. 2004;71:19-23 pubmed
    ..These data show that alkylglycerols inhibit partially and specifically PAF-induced platelet stimulation and suggest that this effect could result from interfering with PAF receptors...

More Information


  1. Schaff M, Receveur N, Bourdon C, Wurtz V, Denis C, Orend G, et al. Novel function of tenascin-C, a matrix protein relevant to atherosclerosis, in platelet recruitment and activation under flow. Arterioscler Thromb Vasc Biol. 2011;31:117-24 pubmed publisher
    ..This study provides evidence that TN-C serves as a novel adhesive matrix for platelets in a context that is relevant to atherothrombosis. ..