Experts and Doctors on phagocytosis in Italy

Summary

Locale: Italy
Topic: phagocytosis

Top Publications

  1. Tullio V, Cuffini A, Fazari S, Carlone N. Cefonicid potentiation of human macrophage activity. Microbiologica. 1992;15:219-26 pubmed
    ..Sub-MIC cefonicid pretreatment of macrophages did not reduce phagocytosis and killing, confirming the inability of beta-lactam antibiotics to cross biological membranes. ..
  2. Fontana G, Licciardi M, Mansueto S, Schillaci D, Giammona G. Amoxicillin-loaded polyethylcyanoacrylate nanoparticles: influence of PEG coating on the particle size, drug release rate and phagocytic uptake. Biomaterials. 2001;22:2857-65 pubmed
    ..pylori by peroral administration. ..
  3. Galdiero F, Romano Carratelli C, Nuzzo I, Bentivoglio C, Galdiero E. Further characterization of the impaired protective function in mice fed with lipid diet. Med Microbiol Immunol. 1989;178:297-308 pubmed
  4. Prato M, Giribaldi G, Polimeni M, Gallo V, Arese P. Phagocytosis of hemozoin enhances matrix metalloproteinase-9 activity and TNF-alpha production in human monocytes: role of matrix metalloproteinases in the pathogenesis of falciparum malaria. J Immunol. 2005;175:6436-42 pubmed
    ..Pharmacological inhibition of MMP-9 may offer a new chance to control pathogenic mechanisms in malaria. ..
  5. Antonucci F, Alpar A, Kacza J, Caleo M, Verderio C, Giani A, et al. Cracking down on inhibition: selective removal of GABAergic interneurons from hippocampal networks. J Neurosci. 2012;32:1989-2001 pubmed publisher
  6. Leidi M, Gotti E, Bologna L, Miranda E, Rimoldi M, Sica A, et al. M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro. J Immunol. 2009;182:4415-22 pubmed publisher
    ..Our data suggest that cytokines secreted by lymphoma cells can favor alternate activation of macrophages with a high phagocytic capacity toward rituximab-opsonized targets. ..
  7. Tosi D, Valenti R, Cova A, Sovena G, Huber V, Pilla L, et al. Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens. J Immunol. 2004;172:5363-70 pubmed
    ..Together, our data suggest that the ability of IFN-DCs to efficiently prime anti-tumor CD8(+) T lymphocytes relied mostly on the positive cross-talk occurring between DCs and NK cells upon stimulation with IFN-alpha. ..
  8. Zingarelli B, Squadrito F, Ioculano M, Altavilla D, Bussolino F, Campo G, et al. Platelet activating factor interaction with tumor necrosis factor and myocardial depressant factor in splanchnic artery occlusion shock. Eur J Pharmacol. 1992;222:13-9 pubmed
    ..e. TNF-alpha and myocardial depressant factor) that are relevant to shock. ..
  9. Cima F, Matozzo V, Marin M, Ballarin L. Haemocytes of the clam Tapes philippinarum (Adams & Reeve, 1850): morphofunctional characterisation. Fish Shellfish Immunol. 2000;10:677-93 pubmed

More Information

Publications73

  1. Canale P, Squadrito F, Altavilla D, Ioculano M, Campo G, Squadrito G, et al. Beneficial effects of BAY u3405, a novel thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock. Pharmacology. 1994;49:376-85 pubmed
    ..Our data are consistent with an involvement of thromboxane A2 in splanchnic artery occlusion shock and suggest that BAY u3405 might be of benefit in low-flow states such as circulatory shock. ..
  2. Saccheri F, Pozzi C, Avogadri F, Barozzi S, Faretta M, Fusi P, et al. Bacteria-induced gap junctions in tumors favor antigen cross-presentation and antitumor immunity. Sci Transl Med. 2010;2:44ra57 pubmed publisher
    ..In conclusion, we exploited an antimicrobial response present in tumor cells to activate cytotoxic CD8 T cells specific for tumor-generated peptides that could directly recognize and kill tumor cells. ..
  3. Biswas S, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, et al. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). Blood. 2006;107:2112-22 pubmed
    ..Thus, profiling of TAMs from a murine sarcoma revealed unexpected expression of IFN-inducible chemokines, associated with an M2 phenotype (IL-10high, IL-12low), and divergent regulation of the NF-kappaB versus the IRF-3/STAT1 pathway. ..
  4. Blasi E, Brozzetti A, Francisci D, Neglia R, Cardinali G, Bistoni F, et al. Evidence of microevolution in a clinical case of recurrent Cryptococcus neoformans meningoencephalitis. Eur J Clin Microbiol Infect Dis. 2001;20:535-43 pubmed
  5. Vulcano M, Dusi S, Lissandrini D, Badolato R, Mazzi P, Riboldi E, et al. Toll receptor-mediated regulation of NADPH oxidase in human dendritic cells. J Immunol. 2004;173:5749-56 pubmed
    ..It is likely that the selective regulation of oxygen radicals production by pathogen-activated DC may function to limit pathogen dissemination during DC trafficking to secondary lymphoid tissues. ..
  6. Canesi L, Lorusso L, Ciacci C, Betti M, Rocchi M, Pojana G, et al. Immunomodulation of Mytilus hemocytes by individual estrogenic chemicals and environmentally relevant mixtures of estrogens: in vitro and in vivo studies. Aquat Toxicol. 2007;81:36-44 pubmed
    ..The results indicate that Mytilus immune parameters can be suitably utilized to evaluate the estrogenic potential of environmental samples. ..
  7. Decleva E, Menegazzi R, Busetto S, Patriarca P, Dri P. Common methodology is inadequate for studies on the microbicidal activity of neutrophils. J Leukoc Biol. 2006;79:87-94 pubmed
  8. Paroni M, Moalli F, Nebuloni M, Pasqualini F, Bonfield T, Nonis A, et al. Response of CFTR-deficient mice to long-term chronic Pseudomonas aeruginosa infection and PTX3 therapy. J Infect Dis. 2013;208:130-8 pubmed publisher
    ..These findings represent a step forward in demonstrating the therapeutic potential of PTX3 in CF. ..
  9. Schwarzer E, De Matteis F, Giribaldi G, Ulliers D, Valente E, Arese P. Hemozoin stability and dormant induction of heme oxygenase in hemozoin-fed human monocytes. Mol Biochem Parasitol. 1999;100:61-72 pubmed
    ..In conclusion, our data indicate that lack of induction of HO1 is due to the intrinsic structural characteristics of hemozoin and not to hemozoin-mediated impairment of the mechanism of HO1 induction. ..
  10. Drago L, De Vecchi E, Fassina M, Mombelli B, Bonaccorso C, Gismondo M. Antimycotic activity and phagocytosis effects of econazole in combination with ibuprofen isobuthanolammonium against vaginal strains. J Chemother. 2000;12:509-15 pubmed
    ..We conclude that the addition of ibuprofen isobuthanolammonium to econazole provides better in vitro antifungal activity. However, further studies are needed to elucidate the in vivo action of this formulation. ..
  11. Squadrito F, Sturniolo R, Altavilla D, Campo G, Trimarchi G, Scuri R, et al. Effects of fructose 1,6-diphosphate on splanchnic artery occlusion shock in the rat. Resuscitation. 1989;18:299-307 pubmed
    ..9 +/- 0.4%) and reduced plasma MDF levels (77 +/- 3 units/ml). Equivalent doses of fructose and inorganic phosphate did not improve survival, as well as lower doses of FDP. These results suggest a beneficial effect of FDP in SAO shock. ..
  12. Riganti C, Castella B, Kopecka J, Campia I, Coscia M, Pescarmona G, et al. Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells. PLoS ONE. 2013;8:e60975 pubmed publisher
    ..These data indicate that MDR+ cells have an hyper-active mevalonate pathway which is targetable with zoledronic acid to antagonize their ability to withstand chemotherapy-induced cytotoxicity and escape immunogenic cell death. ..
  13. Monti P, Mercalli A, Leone B, Valerio D, Allavena P, Piemonti L. Rapamycin impairs antigen uptake of human dendritic cells. Transplantation. 2003;75:137-45 pubmed
    ..Rapamycin has a unique and profound inhibitory effect on DC function, which seems to be at least in part mediated by the FKBP immunophilins. ..
  14. Ayi K, Giribaldi G, Skorokhod A, Schwarzer E, Prendergast P, Arese P. 16alpha-bromoepiandrosterone, an antimalarial analogue of the hormone dehydroepiandrosterone, enhances phagocytosis of ring stage parasitized erythrocytes: a novel mechanism for antimalarial activity. Antimicrob Agents Chemother. 2002;46:3180-4 pubmed
    ..We propose that enhanced ring phagocytosis due to exposure of negatively charged membrane phospholipids may explain the antimalarial activity of EPI. ..
  15. Bondanza A, Zimmermann V, Dell Antonio G, Dal Cin E, Capobianco A, Sabbadini M, et al. Cutting edge: dissociation between autoimmune response and clinical disease after vaccination with dendritic cells. J Immunol. 2003;170:24-7 pubmed
    ..The data suggest that DC vaccination consistently triggers autoimmune responses. However, clinical autoimmunity develops in susceptible subjects only. ..
  16. Polimeni M, Valente E, Aldieri E, Khadjavi A, Giribaldi G, Prato M. Role of 15-hydroxyeicosatetraenoic acid in hemozoin-induced lysozyme release from human adherent monocytes. Biofactors. 2013;39:304-14 pubmed publisher
    ..Collectively, these data suggest that 15-HETE plays a major role in nHZ-enhanced monocyte degranulation. ..
  17. Capsoni F, Ongari A, Frigerio E, Taglioni M, Altomare G. Effect of Efalizumab on neutrophil and monocyte functions in patients with psoriasis. Int J Immunopathol Pharmacol. 2008;21:437-45 pubmed
    ..Our findings suggest that neutrophils and monocytes may be among the targets of efalizumab activity in patients with psoriasis. ..
  18. Ramoino P, Usai C, Maccione S, Beltrame F, Diaspro A, Fato M, et al. Effect of the bioactive metabolite euplotin C on phagocytosis and fluid-phase endocytosis in the single-celled eukaryote Paramecium. Aquat Toxicol. 2007;85:67-75 pubmed
    ..The effect of euplotin C on the food vacuole formation and fluid-phase endocytosis is apparently mediated by a modification of microtubule network. ..
  19. Capsoni F, Sarzi Puttini P, Atzeni F, Minonzio F, Bonara P, Doria A, et al. Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis. Arthritis Res Ther. 2005;7:R250-5 pubmed
  20. Trevisani F, Castelli E, Foschi F, Parazza M, Loggi E, Bertelli M, et al. Impaired tuftsin activity in cirrhosis: relationship with splenic function and clinical outcome. Gut. 2002;50:707-12 pubmed
    ..Such an abnormality appears to be related to impaired splenic function and severity of cirrhosis, and probably favours the occurrence of bacterial infections. ..
  21. Adinolfi L, Utili R, Dilillo M, Tripodi M, Attanasio V, Ruggiero G. Intracellular activity of cefamandole and aztreonam against phagocytosed Escherichia coli and Staphylococcus aureus. J Antimicrob Chemother. 1989;24:927-35 pubmed
    ..coli that seems at least in part due to a positive cooperation of antibiotics with the O2-independent microbicidal system of macrophages. ..
  22. McDonald P, Cassatella M. Activation of transcription factor NF-kappa B by phagocytic stimuli in human neutrophils. FEBS Lett. 1997;412:583-6 pubmed
    ..To our knowledge, this represents the first demonstration that phagocytic stimuli can induce NF-kappa B activation in human neutrophils. ..
  23. Blasi E, Barluzzi R, Mazzolla R, Tancini B, Saleppico S, Puliti M, et al. Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. J Neuroimmunol. 1995;58:111-6 pubmed
    ..neoformans overcomes host defenses. ..
  24. Dri P, Cramer R, Mittenzwei H, Patriarca P. Dual effect of a protein-free hemodialysate on the oxygen uptake of phagocytosing human polymorphonuclear leucocytes. Arzneimittelforschung. 1989;39:1565-7 pubmed
    ..The results are discussed in the light of the known clinical effects of the hemodialysate. ..
  25. Carlone N, Cufini A, Tullio V, Sassella D. Comparative effects of roxithromycin and erythromycin on cellular immune functions in vitro. 2. Chemotaxis and phagocytosis of 3H-Staphylococcus aureus by human macrophages. Microbios. 1989;58:17-25 pubmed
    ..Erythromycin displayed a less stimulating effect. Pre-incubation of macrophages with the drugs caused a depression of staphylococcal uptake by phagocytes. Macrophage chemotaxis was unchanged in the presence of both macrolides. ..
  26. Maugeri N, Rovere Querini P, Evangelista V, Covino C, Capobianco A, Bertilaccio M, et al. Neutrophils phagocytose activated platelets in vivo: a phosphatidylserine, P-selectin, and {beta}2 integrin-dependent cell clearance program. Blood. 2009;113:5254-65 pubmed publisher
    ..The data suggest that the interaction between circulating platelets and neutrophils influences innate immune functions, possibly contributing to regulate vascular inflammation. ..
  27. Giglio A, Battistella S, Talarico F, Brandmayr T, Giulianini P. Circulating hemocytes from larvae and adults of Carabus (Chaetocarabus) lefebvrei Dejean 1826 (Coleoptera, Carabidae): cell types and their role in phagocytosis after in vivo artificial non-self-challenge. Micron. 2008;39:552-8 pubmed
    ..We think that these differences could be correlated with the peculiar morphology (less chitinization) and ecology of larval stages that are more sensitive to pathogens than adults. ..
  28. Braga P, Sala M, Mancini L, Da Sasso M. Phagocytosis and intracellular killing of rokitamycin-exposed staphylococci by human polymorphonuclear leukocytes. Chemotherapy. 1998;44:42-9 pubmed
    ..This effect can be correlated with the high uptake of RKM by PMNs (cellular/extracellular ratio congruent to 30.5). The relevance of these in vitro observations to clinical situations remains to be further investigated. ..
  29. Rinaldi M, Moroni P, Leino L, Laihia J, Paape M, Bannerman D. Effect of cis-urocanic acid on bovine neutrophil generation of reactive oxygen species. J Dairy Sci. 2006;89:4188-201 pubmed
    ..Together, these data suggest that cis-UCA inhibits the tissue-damaging generation of extracellular ROS while preserving neutrophil bactericidal activity...
  30. Atzeni F, Schena M, Ongari A, Carrabba M, Bonara P, Minonzio F, et al. Induction of CD69 activation molecule on human neutrophils by GM-CSF, IFN-gamma, and IFN-alpha. Cell Immunol. 2002;220:20-9 pubmed
    ..CD69 cross-linking on GM-CSF-primed neutrophils sinergized with LPS and increased TNF-alpha production and secretion suggesting a role for CD69-positive neutrophils in the pathogenesis and maintenance of different inflammatory diseases. ..
  31. Maugeri N, Malato S, Femia E, Pugliano M, Campana L, Lunghi F, et al. Clearance of circulating activated platelets in polycythemia vera and essential thrombocythemia. Blood. 2011;118:3359-66 pubmed publisher
  32. Grimaldi A, D Alessandro G, Golia M, Grössinger E, Di Angelantonio S, Ragozzino D, et al. KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages. Cell Death Dis. 2016;7:e2174 pubmed publisher
    ..Our data indicate that KCa3.1 channels are involved in the inhibitory effects exerted by the glioma microenvironment on infiltrating M/M?, suggesting a possible role as therapeutic targets in glioma. ..
  33. Rotondo R, Bertolotto M, Barisione G, Astigiano S, Mandruzzato S, Ottonello L, et al. Exocytosis of azurophil and arginase 1-containing granules by activated polymorphonuclear neutrophils is required to inhibit T lymphocyte proliferation. J Leukoc Biol. 2011;89:721-7 pubmed publisher
    ..These findings suggest that PMNs, recruited at sites of immune complex deposition, induce ARG1-dependent immune suppression through concomitant exocytosis of gelatinase and azurophil granules. ..
  34. Gallo V, Skorokhod O, Schwarzer E, Arese P. Simultaneous determination of phagocytosis of Plasmodium falciparum-parasitized and non-parasitized red blood cells by flow cytometry. Malar J. 2012;11:428 pubmed publisher
    ..The presented method may help to analyse the factors or conditions that modulate the share of np-RBC removal in vitro and in vivo and lead to a better understanding of the pathogenesis of SMA. ..
  35. Cavaliere F, Prezzo A, Bilotta C, Iacobini M, Quinti I. The lack of BTK does not impair monocytes and polymorphonuclear cells functions in X-linked agammaglobulinemia under treatment with intravenous immunoglobulin replacement. PLoS ONE. 2017;12:e0175961 pubmed publisher
    ..In monocytes, the IVIg reduce the oxidative burst and phagocytosis even if these functions remained efficient. ..
  36. Costa C, Germena G, Hirsch E. Dissection of the interplay between class I PI3Ks and Rac signaling in phagocytic functions. ScientificWorldJournal. 2010;10:1826-39 pubmed publisher
  37. Fumagalli S, Perego C, Ortolano F, De Simoni M. CX3CR1 deficiency induces an early protective inflammatory environment in ischemic mice. Glia. 2013;61:827-42 pubmed publisher
    ..Our data show that in cx3cr1(-/-) mice protection from ischemia at early time points after injury is associated with a protective inflammatory milieu, characterized by the promotion of M2 polarization markers. ..
  38. Gourlay L, Peri C, Ferrer Navarro M, Conchillo Solé O, Gori A, Rinchai D, et al. Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology. Chem Biol. 2013;20:1147-56 pubmed publisher
    ..Our strategy represents a step in the development of immunodiagnostics, in the production of specific antibodies and in the optimization of antigens for vaccine development, starting from structural and physicochemical principles. ..
  39. Sturla L, Fresia C, Guida L, Bruzzone S, Scarfi S, Usai C, et al. LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells. J Biol Chem. 2009;284:28045-57 pubmed publisher
    ..Identification of LANCL2 as a critical component of the ABA-sensing protein complex will enable the screening of synthetic ABA antagonists as prospective new anti-inflammatory and anti-diabetic agents...
  40. Stefano L, Racchetti G, Bianco F, Passini N, Gupta R, Panina Bordignon P, et al. The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor. J Neurochem. 2009;110:284-94 pubmed publisher
    ..It might in contrast be appropriate for the binding of TREM2 to Hsp60 exposed at the surface of cells closely interacting with microglia. The ensuing stimulation of phagocytosis could play protective effects on the brain. ..
  41. Katsumiti A, Gilliland D, Arostegui I, Cajaraville M. Cytotoxicity and cellular mechanisms involved in the toxicity of CdS quantum dots in hemocytes and gill cells of the mussel Mytilus galloprovincialis. Aquat Toxicol. 2014;153:39-52 pubmed publisher
    ..25 mg Cd/L but not in those exposed to ionic Cd, indicating a particle-specific effect on phagocytosis. In conclusion, cell-mediated immunity and gill cell function represent significant targets for CdS QDs toxicity...
  42. Rescigno M. Identification of a new mechanism for bacterial uptake at mucosal surfaces, which is mediated by dendritic cells. Pathol Biol (Paris). 2003;51:69-70 pubmed
    ..Rather, DC can actively participate to microbial entry across mucosal surfaces by creeping between epithelial cells and by internalizing bacteria via their dendrites. ..
  43. Granucci F, Petralia F, Urbano M, Citterio S, Di Tota F, Santambrogio L, et al. The scavenger receptor MARCO mediates cytoskeleton rearrangements in dendritic cells and microglia. Blood. 2003;102:2940-7 pubmed
    ..Thus, the MARCO receptor is important for actin cytoskeleton rearrangements and the down-regulation of antigen uptake function during DC and microglial cell maturation. ..
  44. Falasca L, Iadevaia V, Ciccosanti F, Melino G, Serafino A, Piacentini M. Transglutaminase type II is a key element in the regulation of the anti-inflammatory response elicited by apoptotic cell engulfment. J Immunol. 2005;174:7330-40 pubmed
    ..These results help explain the autoimmune phenotype developed by these mice and suggest that TG2 is a key regulatory element of the anti-inflammatory features of apoptosis. ..
  45. Braga P, Piatti G, Dal Sasso M, Maci S, Blasi F. Thymomodulin stimulates phagocytosis in vitro by rat macrophages and human polymorphonuclear cells. J Chemother. 1993;5:313-6 pubmed
  46. Ma B, Day J, Phillips H, Slootsky B, Tolosano E, Doré S. Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage. J Neuroinflammation. 2016;13:26 pubmed publisher
    ..This study suggests that microglial cells contribute to hemoglobin-heme clearance after ICH; however, the resultant iron overloads in microglia appear to decrease Iba1 expression and to further inhibit microglial phagocytosis. ..
  47. Jaillon S, Moalli F, Ragnarsdottir B, Bonavita E, Puthia M, Riva F, et al. The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection. Immunity. 2014;40:621-32 pubmed publisher
    ..These results suggest that PTX3 is an essential component of innate resistance against UTIs. Thus, the cellular and humoral arms of innate immunity exert complementary functions in mediating resistance against UTIs. ..
  48. Garlanda C, Hirsch E, Bozza S, Salustri A, De Acetis M, Nota R, et al. Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response. Nature. 2002;420:182-6 pubmed
    ..Thus, the long pentraxin Ptx3 is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents, in particular to the opportunistic fungal pathogen Aspergillus fumigatus. ..
  49. Rossi G, Capitani L, Ceciliani F, Restelli L, Paltrinieri S. Hyposialylated ?1-acid glycoprotein inhibits phagocytosis of feline neutrophils. Res Vet Sci. 2013;95:465-71 pubmed publisher
    ..This study demonstrated that hyposialylated fAGP down-regulates the phagocytic activity of feline neutrophils. ..
  50. Codolo G, Plotegher N, Pozzobon T, Brucale M, Tessari I, Bubacco L, et al. Triggering of inflammasome by aggregated ?-synuclein, an inflammatory response in synucleinopathies. PLoS ONE. 2013;8:e55375 pubmed publisher
    ..Taken together, our data support the notion that fibrillar ?Syn, likely released by neuronal degeneration, acts as an endogenous trigger inducing a strong inflammatory response in PD. ..
  51. Gagliardi M, Teloni R, Giannoni F, Pardini M, Sargentini V, Brunori L, et al. Mycobacterium bovis Bacillus Calmette-Guerin infects DC-SIGN- dendritic cell and causes the inhibition of IL-12 and the enhancement of IL-10 production. J Leukoc Biol. 2005;78:106-13 pubmed
  52. Tortorella C, Ottolenghi A, Moretti A, Jirillo E, Antonaci S. Thymostimulin administration modulates polymorph metabolic pathway in patients with chronic obstructive pulmonary disease. Immunopharmacol Immunotoxicol. 1992;14:421-37 pubmed
    ..Furthermore, COPD subjects exhibited a significant improvement of their clinical status as assessed during a one-year followup. All together, these findings suggest a potential role for thymostimulin in the treatment of COPD patients. ..
  53. Nencioni A, Schwarzenberg K, Brauer K, Schmidt S, Ballestrero A, Grunebach F, et al. Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation. Blood. 2006;108:551-8 pubmed
    ..These compounds could prove useful for tuning TLR signaling and for the treatment of inflammatory and immune-mediated disorders. ..
  54. Risso A, Turello M, Biffoni F, Antonutto G. Red blood cell senescence and neocytolysis in humans after high altitude acclimatization. Blood Cells Mol Dis. 2007;38:83-92 pubmed
    ..50% (+/-7) to 97.90% (+/-2.00)). Furthermore, the remaining young and middle-aged RBCs had acquired a senescent-like phenotype, which may account for their increased susceptibility to phagocytosis. ..
  55. Pacello F, Ceci P, Ammendola S, Pasquali P, Chiancone E, Battistoni A. Periplasmic Cu,Zn superoxide dismutase and cytoplasmic Dps concur in protecting Salmonella enterica serovar Typhimurium from extracellular reactive oxygen species. Biochim Biophys Acta. 2008;1780:226-32 pubmed publisher
    ..Moreover, the nearly additive effect of the sodC and dps mutations suggests that localization of antioxidant enzymes in different cellular compartments is required for bacterial resistance to extracytoplasmic oxidative attack...
  56. Disanza A, Scita G. Cytoskeletal regulation: coordinating actin and microtubule dynamics in membrane trafficking. Curr Biol. 2008;18:R873-5 pubmed publisher
    ..The discovery of a new NPF, WHAMM, reveals unexpected connections between the actin and microtubule cytoskeletons and membrane dynamics during ER-to-Golgi transport. ..
  57. Trielli F, Cervia D, Di Giuseppe G, Ristori C, Kruppel T, Burlando B, et al. Action mechanisms of the secondary metabolite euplotin C: signaling and functional role in Euplotes. J Eukaryot Microbiol. 2008;55:365-73 pubmed
    ..vannus. These results suggest that euplotin C exerts a marked disruption of those homeostatic mechanisms whose efficiency represents the essential prerequisite to face the challenges of the interstitial environment...
  58. Canesi L, Lorusso L, Ciacci C, Betti M, Gallo G. Effects of the brominated flame retardant tetrabromobisphenol-A (TBBPA) on cell signaling and function of Mytilus hemocytes: involvement of MAP kinases and protein kinase C. Aquat Toxicol. 2005;75:277-87 pubmed
  59. Scarfi S, Magnone M, Ferraris C, Pozzolini M, Benvenuto F, Benatti U, et al. Ascorbic acid pre-treated quartz stimulates TNF-alpha release in RAW 264.7 murine macrophages through ROS production and membrane lipid peroxidation. Respir Res. 2009;10:25 pubmed publisher
    ..Taken together these data suggest that an impairment of pulmonary macrophage phagocytosis, i.e. in the case of alcoholic subjects, could potentiate lung disease in silica-exposed individuals. ..
  60. Giribaldi G, Valente E, Khadjavi A, Polimeni M, Prato M. Macrophage inflammatory protein-1alpha mediates matrix metalloproteinase-9 enhancement in human adherent monocytes fed with malarial pigment. Asian Pac J Trop Med. 2011;4:925-30 pubmed publisher
  61. Ciacci C, Barmo C, Fabbri R, Canonico B, Gallo G, Canesi L. Immunomodulation in Mytilus galloprovincialis by non-toxic doses of hexavalent chromium. Fish Shellfish Immunol. 2011;31:1026-33 pubmed publisher
    ..Overall, the results indicate that exposure to non-toxic, environmentally relevant concentrations of Cr(VI) can modulate functional and molecular immune parameters in M. galloprovincialis. ..
  62. Sillo A, Matthias J, Konertz R, Bozzaro S, Eichinger L. Salmonella typhimurium is pathogenic for Dictyostelium cells and subverts the starvation response. Cell Microbiol. 2011;13:1793-811 pubmed publisher
    ..Inhibition of the aggregation competence and chemotactic streaming of aggregation-competent cells in the presence of Salmonella suggests interference with cAMP signalling...
  63. Granucci F, Feau S, Angeli V, Trottein F, Ricciardi Castagnoli P. Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming. J Immunol. 2003;170:5075-81 pubmed
    ..When early activated DCs interact with T cells, IL-2 produced by DCs is enriched at the site of cell-cell contact, confirming the importance of DCs-derived IL-2 in T cell activation. ..
  64. Bertelli A, Ferrara F, Diana G, Fulgenzi A, Corsi M, Ponti W, et al. Resveratrol, a natural stilbene in grapes and wine, enhances intraphagocytosis in human promonocytes: a co-factor in antiinflammatory and anticancer chemopreventive activity. Int J Tissue React. 1999;21:93-104 pubmed