Experts and Doctors on pectobacterium carotovorum in Finland


Locale: Finland
Topic: pectobacterium carotovorum

Top Publications

  1. Hyytiäinen H, Montesano M, Palva E. Global regulators ExpA (GacA) and KdgR modulate extracellular enzyme gene expression through the RsmA-rsmB system in Erwinia carotovora subsp. carotovora. Mol Plant Microbe Interact. 2001;14:931-8 pubmed
    ..This study indicates a central role for the RsmA-rsmB regulatory system during pathogenesis, integrating signals from the ExpA (GacA) and KdgR global regulators of extracellular enzyme production in E. carotovora subsp. carotovora. ..
  2. Lehtimäki S, Rantakari A, Routtu J, Tuikkala A, Li J, Virtaharju O, et al. Characterization of the hrp pathogenicity cluster of Erwinia carotovora subsp. carotovora: high basal level expression in a mutant is associated with reduced virulence. Mol Genet Genomics. 2003;270:263-72 pubmed
    ..but this is the first demonstration that high basal-level expression of hrp -regulated genes may actually have a negative impact on disease progress in a susceptible host plant. ..
  3. Mattinen L, Somervuo P, Nykyri J, Nissinen R, Kouvonen P, Corthals G, et al. Microarray profiling of host-extract-induced genes and characterization of the type VI secretion cluster in the potato pathogen Pectobacterium atrosepticum. Microbiology. 2008;154:2387-96 pubmed publisher
    ..The results suggest that the type VI secretion system of P. atrosepticum is needed for secretion of Hcps but not for virulence on its host plant, potato. ..
  4. Brader G, Mikkelsen M, Halkier B, Tapio Palva E. Altering glucosinolate profiles modulates disease resistance in plants. Plant J. 2006;46:758-67 pubmed
    ..Arabidopsis with modified GS profiles provide important tools for evaluating the biological effects of individual GSs and thereby show potential as biotechnological tools for the generation of plants with tailor-made disease resistance. ..
  5. Brader G, Tas E -, Palva E. Jasmonate-dependent induction of indole glucosinolates in Arabidopsis by culture filtrates of the nonspecific pathogen Erwinia carotovora. Plant Physiol. 2001;126:849-60 pubmed
    ..The breakdown products of IGS and other glucosinolates were able to inhibit growth of E. carotovora. The results suggest that IGS is of importance in the defense against bacterial pathogens. ..
  6. Papageorgiou A, Posypanova G, Andersson C, Sokolov N, Krasotkina J. Structural and functional insights into Erwinia carotovora L-asparaginase. FEBS J. 2008;275:4306-16 pubmed publisher
    ..carotovora asparaginase has limited potential as an antileukemic drug, despite its promising low glutaminase activity. Our analysis may be applicable to the therapeutic evaluation of other asparaginases as well. ..
  7. Rantakari A, Virtaharju O, Vähämiko S, Taira S, Palva E, Saarilahti H, et al. Type III secretion contributes to the pathogenesis of the soft-rot pathogen Erwinia carotovora: partial characterization of the hrp gene cluster. Mol Plant Microbe Interact. 2001;14:962-8 pubmed
    ..The hrcC- strain was able to multiply and cause disease in Arabidopsis, but the population kinetics were altered so that growth was delayed during the early stages of infection...
  8. Kariola T, Palomäki T, Brader G, Palva E. Erwinia carotovora subsp. carotovora and Erwinia-derived elicitors HrpN and PehA trigger distinct but interacting defense responses and cell death in Arabidopsis. Mol Plant Microbe Interact. 2003;16:179-87 pubmed
    ..The two elicitors produced by E. carotovora subsp. carotovora also cooperate in triggering increased production of superoxide and lesion formation...
  9. Hyytiäinen H, Sjöblom S, Palomaki T, Tuikkala A, Tapio Palva E. The PmrA-PmrB two-component system responding to acidic pH and iron controls virulence in the plant pathogen Erwinia carotovora ssp. carotovora. Mol Microbiol. 2003;50:795-807 pubmed
    ..We propose that PmrA-PmrB TCS is involved in controlling of bacterial response to external pH and iron and is crucial for bacterial virulence and survival in planta...

More Information


  1. Mattinen L, Tshuikina M, Mäe A, Pirhonen M. Identification and characterization of Nip, necrosis-inducing virulence protein of Erwinia carotovora subsp. carotovora. Mol Plant Microbe Interact. 2004;17:1366-75 pubmed
    ..A mutant strain of E. carotovora subsp. carotovora lacking the nip gene showed reduced virulence in potato tuber assay but was unaffected in virulence in potato stem or on other tested host plants...
  2. Brader G, Sjöblom S, Hyytiäinen H, Sims Huopaniemi K, Palva E. Altering substrate chain length specificity of an acylhomoserine lactone synthase in bacterial communication. J Biol Chem. 2005;280:10403-9 pubmed
    ..Our data identify critical residues that define the size of the substrate-binding pocket of the AHSL synthase and will help in understanding and manipulating this bacterial language...