Experts and Doctors on northern blotting in Japan

Summary

Locale: Japan
Topic: northern blotting

Top Publications

  1. Ito K, Shinomura T, Zako M, Ujita M, Kimata K. Multiple forms of mouse PG-M, a large chondroitin sulfate proteoglycan generated by alternative splicing. J Biol Chem. 1995;270:958-65 pubmed
  2. Ojima T, Takagi H, Suzuma K, Oh H, Suzuma I, Ohashi H, et al. EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown. Am J Pathol. 2006;168:331-9 pubmed
    ..0 +/- 10.0% (P < 0.05). These findings suggest a novel therapeutic potential for EphA2/ephrinA1 in the treatment of neovascularization and vasopermeability abnormalities in diabetic retinopathy...
  3. Ino H, Ishizuka T, Chiba T, Tatibana M. Expression of CDK5 (PSSALRE kinase), a neural cdc2-related protein kinase, in the mature and developing mouse central and peripheral nervous systems. Brain Res. 1994;661:196-206 pubmed
    ..The expression pattern of CDK5 is quite in contrast with that of CDC2. The fact that CDK5 is expressed in terminally differentiated non-dividing neurons predicts an alternative function(s) in addition to controlling the cell cycle. ..
  4. Yoshida S, Marikawa Y, Satoh N. Posterior end mark, a novel maternal gene encoding a localized factor in the ascidian embryo. Development. 1996;122:2005-12 pubmed
    ..The ascidian tadpole is regarded as a prototype of vertebrates, implying a similar function of pem in vertebrate embryogenesis. ..
  5. Naitoh H, Mori C, Nishimura Y, Shiota K. Altered expression of retinoic acid (RA) receptor mRNAs in the fetal mouse secondary palate by all-trans and 13-cis RAs: implications for RA-induced teratogenesis. J Craniofac Genet Dev Biol. 1998;18:202-10 pubmed
  6. Nagata T, Morita T, Nozaki M, Matsushiro A. Expression of H-2K and H-2D genes by PYS-2 teratocarcinoma cells. Biochem Biophys Res Commun. 1988;157:648-56 pubmed
    ..However, we have not isolated Qa, Tla or other embryonic class I cDNAs from our PYS-2 library. ..
  7. Akao Y, Marukawa O, Morikawa H, Nakao K, Kamei M, Hachiya T, et al. The rck/p54 candidate proto-oncogene product is a 54-kilodalton D-E-A-D box protein differentially expressed in human and mouse tissues. Cancer Res. 1995;55:3444-9 pubmed
    ..In addition, the rck/p54 protein was localized to cytoplasm by immunostaining with the use of laser microscopy and by subcellular fractionation. ..
  8. Fujita Y, Mynlieff M, Dirksen R, Kim M, Niidome T, Nakai J, et al. Primary structure and functional expression of the omega-conotoxin-sensitive N-type calcium channel from rabbit brain. Neuron. 1993;10:585-98 pubmed
    ..Cell-attached patch recordings, with isotonic barium as the charge carrier, revealed distinct single channels with an average slope conductance of 14.3 pS. ..
  9. Kitawaki J, Koshiba H, Ishihara H, Kusuki I, Tsukamoto K, Honjo H. Progesterone induction of 17beta-hydroxysteroid dehydrogenase type 2 during the secretory phase occurs in the endometrium of estrogen-dependent benign diseases but not in normal endometrium. J Clin Endocrinol Metab. 2000;85:3292-6 pubmed

More Information

Publications147 found, 100 shown here

  1. Ayada Y, Kusachi S, Murakami T, Hirohata S, Takemoto S, Komatsubara I, et al. Increased expression of biglycan mRNA in pressure-overloaded rat heart. Clin Exp Hypertens. 2001;23:633-43 pubmed
  2. Ohbayashi T, Oikawa K, Iwata R, Kameta A, Evine K, Isobe T, et al. Dioxin induces a novel nuclear factor, DIF-3, that is implicated in spermatogenesis. FEBS Lett. 2001;508:341-4 pubmed
    ..Thus, these results suggest that DIF-3 may be a target gene mediating the reproductive toxicity induced by TCDD. ..
  3. Nakagawa T, Takane K, Sugimoto T, Izui K, Kouchi H, Hata S. Regulatory regions and nuclear factors involved in nodule-enhanced expression of a soybean phosphoenolpyruvate carboxylase gene: implications for molecular evolution. Mol Genet Genomics. 2003;269:163-72 pubmed
    ..This study suggests that the acquisition of two interdependent cis-acting elements resulted in molecular evolution of the nodule-enhanced GmPEPC7gene. ..
  4. Hirayoshi K, Kudo H, Takechi H, Nakai A, Iwamatsu A, Yamada K, et al. HSP47: a tissue-specific, transformation-sensitive, collagen-binding heat shock protein of chicken embryo fibroblasts. Mol Cell Biol. 1991;11:4036-44 pubmed
    ..Conversely, it is the first serpin family member that is not secreted from cells, which could be explained by acquisition of the RDEL retention signal during evolution. ..
  5. Taira M, Iizasa T, Yamada K, Shimada H, Tatibana M. Tissue-differential expression of two distinct genes for phosphoribosyl pyrophosphate synthetase and existence of the testis-specific transcript. Biochim Biophys Acta. 1989;1007:203-8 pubmed
    ..In the testis, an additional PRPS1-related transcript of 1.4 kb was noted in rats, mice and humans. This transcript may belong to a group of testis-specific gene expressions or functions. ..
  6. Itoh M, Ishihara K, Tomizawa H, Tanaka H, Kobune Y, Ishikawa J, et al. Molecular cloning of murine BST-1 having homology with CD38 and Aplysia ADP-ribosyl cyclase. Biochem Biophys Res Commun. 1994;203:1309-17 pubmed
    ..Restriction fragment length polymorphism (RFLP) was shown in BALB/c, DBA/2 and NZB vs C57BL/6, A/J, CBA/N, NZW, BXSB and MRL/lpr. RFLP was mapped to the 5' portion of the murine BST-1 gene. ..
  7. Moriyama H, Horiuchi H, Nitta T, Fukuhara T. Unusual inheritance of evolutionarily-related double-stranded RNAs in interspecific hybrid between rice plants Oryza sativa and Oryza rufipogon. Plant Mol Biol. 1999;39:1127-36 pubmed
    ..However, the total amount of these dsRNAs in the host cells remained constant (ca. 100 copies/cell). The stringent regulation of the dsRNA copy number may be responsible for their unusual inheritance. ..
  8. Seno H, Sawada M, Fukuzawa H, Morita Y, Takaishi S, Hiai H, et al. Enhanced expression of transforming growth factor (TGF) -alpha precursor and TGF-beta1 during Paneth cell regeneration. Dig Dis Sci. 2001;46:1004-10 pubmed
    ..This unique expression pattern of two growth factors may be involved in rapid regeneration of Paneth cells...
  9. Watanabe M, Ando Y, Todoroki H, Minami H, Hidaka H. Molecular cloning and sequencing of a cDNA clone encoding a new calcium binding protein, named calgizzarin, from rabbit lung. Biochem Biophys Res Commun. 1991;181:644-9 pubmed
    ..2% homology to S-100 alpha, 38.6% to S-100 beta and 40.0% to annexin II light chain, p10. By Northern blot analysis, with pCALG, a band of 1.1 kbp was detected in rabbit lung, suggesting pCALG contains nearly full length of mRNA. ..
  10. Sato S, Fujita N, Kurihara T, Kuwano R, Sakimura K, Takahashi Y, et al. cDNA cloning and amino acid sequence for human myelin-associated glycoprotein. Biochem Biophys Res Commun. 1989;163:1473-80 pubmed
    ..Although the cDNA library used here was prepared from adult human brain poly(A)+ RNA, all five clones obtained corresponded to the mRNA without exon 12 portion. ..
  11. Horinouchi K, Nakamura Y, Yamanaka H, Watabe T, Shiosaka S. Distribution of L1cam mRNA in the adult mouse brain: In situ hybridization and Northern blot analyses. J Comp Neurol. 2005;482:386-404 pubmed
    ..Some long projection neurons such as the pyramidal, mitral, principal neurons of several cranial nuclei, and presumably monoaminergic cells containing noradrenalin, dopamine, and serotonin, expressed high levels of L1cam. ..
  12. Kimura T, Tanizawa O, Mori K, Brownstein M, Okayama H. Structure and expression of a human oxytocin receptor. Nature. 1992;356:526-9 pubmed
    ..The mRNA level in the myometrium is very high at term. We conclude that the increase in receptor number in the myometrium at labour is, at least in part, due to the increase in mRNA. ..
  13. Tomatsu S, Fukuda S, Masue M, Sukegawa K, Fukao T, Yamagishi A, et al. Morquio disease: isolation, characterization and expression of full-length cDNA for human N-acetylgalactosamine-6-sulfate sulfatase. Biochem Biophys Res Commun. 1991;181:677-83 pubmed
  14. Suzuki S, Tone S, Takikawa O, Kubo T, Kohno I, Minatogawa Y. Expression of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase in early concepti. Biochem J. 2001;355:425-9 pubmed
  15. Muragaki Y, Shiota C, Inoue M, Ooshima A, Olsen B, Ninomiya Y. alpha 1(VIII)-collagen gene transcripts encode a short-chain collagen polypeptide and are expressed by various epithelial, endothelial and mesenchymal cells in newborn mouse tissues. Eur J Biochem. 1992;207:895-902 pubmed
  16. Nomura K, Sugawara T, Sato T, Sawamura D, Hashimoto I, Sugita Y, et al. Expression of laminin, type IV procollagen and 230 kDa bullous pemphigoid antigen genes by keratinocytes and fibroblasts in culture: application of the polymerase chain reaction for detection of small amounts of messenger RNA. Arch Dermatol Res. 1994;286:408-13 pubmed
  17. Sato M, Kimura T, Kurokawa K, Fujita Y, Abe K, Masuhara M, et al. Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells. Mech Dev. 2002;113:91-4 pubmed
    ..Immunohistochemical analysis revealed that PGC7 was specifically expressed in early pre-implantation embryos, PGCs and oocytes. These results suggest that PGC7 might play an important role in the development of PGCs and oocytes. ..
  18. Honoki K, Tsutsumi M, Tsujiuchi T, Kondoh S, Shiraiwa K, Miyauchi Y, et al. Expression of the transin, c-fos, and c-jun genes in rat transplantable osteosarcomas and malignant fibrous histiocytomas. Mol Carcinog. 1992;6:122-8 pubmed
    ..Expression of the c-fos and c-jun genes may play a regulatory role in this process...
  19. Shimizu Nishikawa K, Kajiwara K, Kimura M, Katsuki M, Sugaya E. Cloning and expression of SEZ-6, a brain-specific and seizure-related cDNA. Brain Res Mol Brain Res. 1995;28:201-10 pubmed
    ..Based on these findings, it is evident that SEZ-6 encodes a novel type of protein which may be related to seizure. ..
  20. Oyake M, Onodera O, Shiroishi T, Takano H, Takahashi Y, Kominami R, et al. Molecular cloning of murine homologue dentatorubral-pallidoluysian atrophy (DRPLA) cDNA: strong conservation of a polymorphic CAG repeat in the murine gene. Genomics. 1997;40:205-7 pubmed
  21. Aoki T, Koike T, Nakano T, Shibahara K, Nishimura H, Kikuchi H, et al. Rat TAFII31 gene is induced upon programmed cell death in differentiated PC12 cells deprived of NGF. Biochem Biophys Res Commun. 1997;234:230-4 pubmed
    ..Northern analysis of various organs in adult mice showed that expression levels of TAFII31 mRNA were strong in heart but weak in spleen, although this gene is ubiquitously expressed. ..
  22. Kainuma M, Chiba Y, Takeuchi M, Jigami Y. Overexpression of HUT1 gene stimulates in vivo galactosylation by enhancing UDP-galactose transport activity in Saccharomyces cerevisiae. Yeast. 2001;18:533-41 pubmed
    ..These results suggest a role for Hut1p in the transport of UDP--galactose from the cytosol into the Golgi lumen in S. cerevisiae. ..
  23. Tsuruga E, Irie K, Sakakura Y, Yajima T. Tropoelastin expression by periodontal fibroblasts. J Dent Res. 2002;81:198-202 pubmed
    ..These results suggest that the different tropoelastin expression patterns reflect the difference between HGF and HPLF phenotypes. ..
  24. Takekawa M, Itoh F, Hinoda Y, Arimura Y, Toyota M, Sekiya M, et al. Cloning and characterization of a human cDNA encoding a novel putative cytoplasmic protein-tyrosine-phosphatase. Biochem Biophys Res Commun. 1992;189:1223-30 pubmed
    ..Northern blot analysis of PTPG1 mRNA showed a 4.6-kb transcript that was detected in a wide variety of cell lines to suggest its extensive expression. ..
  25. Horikawa S, Sasuga J, Shimizu K, Ozasa H, Tsukada K. Molecular cloning and nucleotide sequence of cDNA encoding the rat kidney S-adenosylmethionine synthetase. J Biol Chem. 1990;265:13683-6 pubmed
    ..Thus, kidney- and liver-type S-adenosylmethionine synthetase isozyme mRNAs were expressed in various tissues with different tissue specificities. ..
  26. Nakamura K, Nishiguchi M, Honda K, Yamane K. The Bacillus subtilis SRP54 homologue, Ffh, has an intrinsic GTPase activity and forms a ribonucleoprotein complex with small cytoplasmic RNA in vivo. Biochem Biophys Res Commun. 1994;199:1394-9 pubmed
    ..These findings provide evidence of a ribonucleoprotein complex in B. subtilis, reminiscent of SRP. ..
  27. Akimoto S, Ono T, Tsutsui H, Kinouchi T, Kataoka K, Ohnishi Y. Complete sequence of the Bacteroides fragilis YCH46 neuraminidase-encoding gene. Biochem Biophys Res Commun. 1994;203:914-21 pubmed
    ..Northern blot analysis using an internal nanH probe revealed a single mRNA species with a length of 1.8 kb that could encode just the neuraminidase. ..
  28. Kondo M, Sutou S. Cloning and molecular characterization of cDNA encoding a mouse male-enhanced antigen-2 (Mea-2): a putative family of the Golgi autoantigen. DNA Seq. 1997;7:71-82 pubmed
    ..In situ hybridization analysis suggested that the Mea-2 gene is expressed in spermatids during spermatogenesis as already shown by Mea-1, suggesting that Mea-2 gene product as well as Mea-1 have also some role for spermatogenesis. ..
  29. Sakakibara H, Hayakawa A, Deji A, Gawronski S, Sugiyama T. His-Asp phosphotransfer possibly involved in the nitrogen signal transduction mediated by cytokinin in maize: molecular cloning of cDNAs for two-component regulatory factors and demonstration of phosphotransfer activity in vitro. Plant Mol Biol. 1999;41:563-73 pubmed
    ..These results indicate that His-Asp phosphotransfer may be involved in the transduction of nitrogen signals mediated by cytokinin, and that multiple response regulators participate in the signaling pathways. ..
  30. Kasagi Y, Tokita R, Nakata T, Imaki T, Minami S. Human growth hormone induces SOCS3 and CIS mRNA increase in the hypothalamic neurons of hypophysectomized rats. Endocr J. 2004;51:145-54 pubmed
  31. Horigane M, Ogihara K, Nakajima Y, Honda H, Taylor D. Identification and expression analysis of an actin gene from the soft tick, Ornithodoros moubata (Acari: Argasidae). Arch Insect Biochem Physiol. 2007;64:186-99 pubmed
    ..In addition, actin expression analyzed by real-time PCR before and after blood feeding was not significantly different indicating OmAct2 is an appropriate internal control for the analysis of gene expression in these ticks...
  32. Fujita T, Shirasawa T, Uchida K, Maruyama N. Isolation of cDNA clone encoding rat senescence marker protein-30 (SMP30) and its tissue distribution. Biochim Biophys Acta. 1992;1132:297-305 pubmed
  33. Kagimoto S, Yamada Y, Kubota A, Someya Y, Ihara Y, Yasuda K, et al. Human somatostatin receptor, SSTR2, is coupled to adenylyl cyclase in the presence of Gi alpha 1 protein. Biochem Biophys Res Commun. 1994;202:1188-95 pubmed
    ..These results indicate that human SSTR2 is functionally coupled to Gi alpha 1 protein but not to Gi alpha 2 or Gi alpha 3 when expressed in CHO cells. ..
  34. Watanabe D, Yamada K, Nishina Y, Tajima Y, Koshimizu U, Nagata A, et al. Molecular cloning of a novel Ca(2+)-binding protein (calmegin) specifically expressed during male meiotic germ cell development. J Biol Chem. 1994;269:7744-9 pubmed
    ..Calmegin is a novel Ca(2+)-binding protein that is specifically expressed in spermatogenesis. The highly regulated, specific, and abundant expression of calmegin suggests that it has important roles in spermatogenesis. ..
  35. Tsuzuki S, Sekiguchi S, Kamimura M, Kiuchi M, Hayakawa Y. A cytokine secreted from the suboesophageal body is essential for morphogenesis of the insect head. Mech Dev. 2005;122:189-97 pubmed
    ..The cytokine-induced fusion of bilateral procephalic lobes is thought to be evolutionarily conserved at least in insects, because of the widespread occurrence of the suboesophageal body in insect embryos. ..
  36. Kageyama R, Sasai Y, Nakanishi S. Molecular characterization of transcription factors that bind to the cAMP responsive region of the substance P precursor gene. cDNA cloning of a novel C/EBP-related factor. J Biol Chem. 1991;266:15525-31 pubmed
    ..These results demonstrate that multiple factors are responsible for transcriptional control of the substance P precursor gene through the CRE region. ..
  37. Ohkubo K, Ogata S, Misumi Y, Takami N, Sinohara H, Ikehara Y. Cloning, structure and expression of cDNA for mouse contrapsin and a related protein. Biochem J. 1991;276 ( Pt 2):337-42 pubmed
    ..The difference in molecular mass between the two may be explained by the fact that the MC-7 sequence contains three potential sites for N-glycosylation, one site less than that of MC-2. ..
  38. Katsuyama M, Nishigaki N, Sugimoto Y, Morimoto K, Negishi M, Narumiya S, et al. The mouse prostaglandin E receptor EP2 subtype: cloning, expression, and northern blot analysis. FEBS Lett. 1995;372:151-6 pubmed
    ..Northern blot analysis revealed that EP2 mRNA is expressed most abundantly in the uterus, followed by the spleen, lung, thymus, ileum, liver, and stomach. ..
  39. Yamazaki N, Shinohara Y, Shima A, Terada H. High expression of a novel carnitine palmitoyltransferase I like protein in rat brown adipose tissue and heart: isolation and characterization of its cDNA clone. FEBS Lett. 1995;363:41-5 pubmed
    ..The transcript corresponding to this cDNA was found to be abundantly expressed in BAT and heart. Therefore, the isolated clone is concluded to encode a CPTI like protein expressed in BAT and heart. ..
  40. Nakanishi I, Moutabarrik A, Hara T, Hatanaka M, Hayashi T, Syouji T, et al. Identification and characterization of membrane cofactor protein (CD46) in the human kidneys. Eur J Immunol. 1994;24:1529-35 pubmed
  41. Adachi Yamada T, Iwami M, Kataoka H, Suzuki A, Ishizaki H. Structure and expression of the gene for the prothoracicotropic hormone of the silkmoth Bombyx mori. Eur J Biochem. 1994;220:633-43 pubmed
    ..One Bombyx brain at day 0 of the fifth larval instar contained 2.4-2.8 pg PTTH mRNA, and this amount did not change markedly during larval-pupal development...
  42. Yamane K, Kawabata M, Tsuruo T. A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator. Eur J Biochem. 1997;250:794-9 pubmed
  43. Shimizu T, Kinugawa K, Sugishita Y, Sugishita K, Harada K, Matsui H, et al. Molecular cloning and expression of inducible nitric oxide synthase in chick embryonic ventricular myocytes. Cardiovasc Res. 1998;38:405-13 pubmed
    ..As like as the nucleotide and amino acid sequences, the myocardial effects of the iNOS may also be evolutionary conserved. ..
  44. Imiya K, Ishizaki T, Seiki T, Saito F, Inazawa J, Oka S, et al. cDNA cloning, genomic structure and chromosomal mapping of the mouse glucuronyltransferase-S involved in the biosynthesis of the HNK-1 carbohydrate epitope. Gene. 2002;296:29-36 pubmed
    ..Southern blot analysis and chromosomal mapping indicated that the mouse GlcAT-S gene is a single copy gene and it was mapped to the A4-B region of mouse chromosome 1. ..
  45. Sazuka T, Kinoshita M, Tomooka Y, Ikawa Y, Noda M, Kumar S. Expression of DRG during murine embryonic development. Biochem Biophys Res Commun. 1992;189:371-7 pubmed
    ..The expression of drg mRNA is greatly reduced in newborn animals. At cellular level, DRG protein can be detected in the cytoplasm. These observations suggest that DRG may play multiple roles in development and normal cell metabolism. ..
  46. Koyata H, Hiraga K. The glycine cleavage system: structure of a cDNA encoding human H-protein, and partial characterization of its gene in patients with hyperglycinemias. Am J Hum Genet. 1991;48:351-61 pubmed
  47. Hata S, Kouchi H, Suzuka I, Ishii T. Isolation and characterization of cDNA clones for plant cyclins. EMBO J. 1991;10:2681-8 pubmed
    ..Other cyclin genes may be present because, on Southern blot analysis of soybean genomic DNA, the isolated soybean cDNA probe hybridized with additional genes under low stringency...
  48. Toda K, Terashima M, Kawamoto T, Sumimoto H, Yokoyama Y, Kuribayashi I, et al. Structural and functional characterization of human aromatase P-450 gene. Eur J Biochem. 1990;193:559-65 pubmed
    ..By chloramphenicol acetyltransferase assay the region up to nucleotide position -242 relative to the transcriptional initiation site is shown to participate in the transcriptional responsiveness to this phorbol ester. ..
  49. Kataoka K, Huh N. A novel beta1,3-N-acetylglucosaminyltransferase involved in invasion of cancer cells as assayed in vitro. Biochem Biophys Res Commun. 2002;294:843-8 pubmed
    ..These results indicate that beta3GnT7 may play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues. ..
  50. Nishimatsu S, Suzuki A, Shoda A, Murakami K, Ueno N. Genes for bone morphogenetic proteins are differentially transcribed in early amphibian embryos. Biochem Biophys Res Commun. 1992;186:1487-95 pubmed
    ..Alkaline phosphatase-inducing assay using the recombinant BMP proteins has shown that at least BMP-2 and -4 have similar activity to mammalian counterparts. ..
  51. Nishi T, Weinstein J, Gillespie W, Paulson J. Complete primary structure of porcine tenascin. Detection of tenascin transcripts in adult submaxillary glands. Eur J Biochem. 1991;202:643-8 pubmed
    ..A survey of tenascin transcripts in various adult rat normal tissues, including brain, revealed that the transcripts were detected only in submaxillary glands where tenascin expression has never been reported. ..
  52. Ogawa J, Kaneko H, Masuda T, Nagata S, Hosoya H, Watanabe K. Novel neural adhesion molecules in the Contactin/F3 subgroup of the immunoglobulin superfamily: isolation and characterization of cDNAs from rat brain. Neurosci Lett. 1996;218:173-6 pubmed
    ..On the other hand, high expression of NB-3 mRNA was observed in spinal cord, as well as in cerebrum and cerebellum. In the other tissues, no expression of NB-2 and NB-3 mRNAs was detected. ..
  53. Nakajima A, Kataoka K, Takata Y, Huh N. Cathepsin-6, a novel cysteine proteinase showing homology with and co-localized expression with cathepsin J/P in the labyrinthine layer of mouse placenta. Biochem J. 2000;349 Pt 3:689-92 pubmed
    ..The structural features including the catalytic triad of the C1 proteinase family were well conserved in cathepsin-6. The expression of cathepsin-6 and cathepsin J/P was restricted in labyrinthine trophoblasts of the placenta. ..
  54. Pattanakitsakul S, Zheng J, Natsuume Sakai S, Takahashi M, Nonaka M. Aberrant splicing caused by the insertion of the B2 sequence into an intron of the complement C4 gene is the basis for low C4 production in H-2k mice. J Biol Chem. 1992;267:7814-20 pubmed
  55. Masaki S, Watanabe T. cDNA sequence analysis of CP94: rat lens fiber cell beaded-filament structural protein shows homology to cytokeratins. Biochem Biophys Res Commun. 1992;186:190-8 pubmed
  56. Yamamoto M, Shoda A, Minamino N, Matsuo H, Nishimatsu S, Ueno N, et al. Expression of thymosin beta 4 gene during Xenopus laevis embryogenesis. Biochem Biophys Res Commun. 1992;184:93-9 pubmed
    ..Northern blot analysis revealed the mRNA is maternally present at a low level and the transcript becomes abundant after gastrulation, supporting the distribution of the peptide. ..
  57. Kuge S, Ihara S, Watanabe E, Watanabe M, Takishima K, Suga T, et al. cDNAs and deduced amino acid sequences of subunits in the binding component of mouse bactericidal factor, Ra-reactive factor: similarity to mannose-binding proteins. Biochemistry. 1992;31:6943-50 pubmed
    ..Southern and Northern blotting analyses using these cDNAs indicated that the P28a and P28b polypeptides are the products of two unique mouse genes which are expressed in hepatic cells. ..
  58. Osugi T, Ding Y, Tanaka H, Kuo C, Do E, Irie Y, et al. Involvement of a single-stranded DNA binding protein, ssCRE-BP/Pur alpha, in morphine dependence. FEBS Lett. 1996;391:11-6 pubmed
    ..The levels of ssCRE-BP/Pur alpha and the transcript were not changed by chronic morphine treatment, however, the levels of an activator of ssCRE-BP/Pur alpha, which is necessary for the DNA binding, may be modulated by the treatment. ..
  59. Endo Y, Sato Y, Matsushita M, Fujita T. Cloning and characterization of the human lectin P35 gene and its related gene. Genomics. 1996;36:515-21 pubmed
    ..Both genes were assigned to a closely related region of chromosome 9 at 9q34. ..
  60. Akagi T, Kamei D, Tsuchiya N, Nishina Y, Horiguchi H, Matsui M, et al. Molecular characterization of a mouse heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its tissue-specific expression. Gene. 2000;245:267-73 pubmed
    ..The signals were confined to the nucleus. The amount of 38kDa JKTBP was estimated to be approximately 1.3x10(7) molecules per HL-60 cell. These results indicate that JKTBP is an abundant, highly conserved nuclear protein. ..
  61. Kawai H, Ota T, Suzuki F, Tatsuka M. Molecular cloning of mouse thioredoxin reductases. Gene. 2000;242:321-30 pubmed
    ..71 cR from D10Mit42, lod>3.0) and the TrxR2 gene to chromosome 16 (placed 22.56 cR from D16Mit34, lod>3.0). Thus, the mouse has at least two distinct nuclear genes for TrxR that have different translocation sites in the cell. ..
  62. Ishisaki Z, Takaishi M, Furuta I, Huh N. Calmin, a protein with calponin homology and transmembrane domains expressed in maturing spermatogenic cells. Genomics. 2001;74:172-9 pubmed
    ..In situ hybridization and immunostaining revealed that calmin was expressed in maturing spermatogenic cells at later stages. Human calmin cDNA was also isolated, and its exon/intron organization was determined. ..
  63. Sutou S, Miwa K, Matsuura T, Kawasaki Y, Ohinata Y, Mitsui Y. Native tesmin is a 60-kilodalton protein that undergoes dynamic changes in its localization during spermatogenesis in mice. Biol Reprod. 2003;68:1861-9 pubmed
    ..The persistent existence of tesmin and its temporally and spatially dynamic localization suggest that tesmin is involved in multiple stages of spermatogenesis and spermiogenesis, possibly during sperm maturation and/or morphogenesis. ..
  64. Imokawa G, Yada Y, Miyagishi M. Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes. J Biol Chem. 1992;267:24675-80 pubmed
    ..These studies suggest that ETs produced and secreted by keratinocytes play an essential role in the maintenance of melanocyte proliferation and UV hyperpigmentation in the epidermis. ..
  65. Nakamura M, Honda Z, Izumi T, Sakanaka C, Mutoh H, Minami M, et al. Molecular cloning and expression of platelet-activating factor receptor from human leukocytes. J Biol Chem. 1991;266:20400-5 pubmed
    ..The production of the mRNA was prominently increased when EoL-1 cells were treated with granulocyte macrophage colony stimulating factor, interleukin-5, and n-butyrate. ..
  66. Matsuura S, Kishi F, Kajii T. Characterization of a 5'-flanking region of the human liver/bone/kidney alkaline phosphatase gene: two kinds of mRNA from a single gene. Biochem Biophys Res Commun. 1990;168:993-1000 pubmed
    ..4 kb upstream from exon 2 and the alternative splicing in the first exon was indicated. RNA blot analysis showed that three species of mRNA of 2.5, 4.1 and 4.7 kilobases were detected in liver and developmentally regulated. ..
  67. Fukuta M, Uchimura K, Nakashima K, Kato M, Kimata K, Shinomura T, et al. Molecular cloning and expression of chick chondrocyte chondroitin 6-sulfotransferase. J Biol Chem. 1995;270:18575-80 pubmed
    ..The amino-terminal amino acid sequence of the purified protein was found in the transmembrane domain, suggesting that the purified protein might be released from the chondrocytes after proteolytic cleavage in the transmembrane domain. ..
  68. Aizawa S, Satoh H, Horie R, Ito K, Choi S, Takeuchi H, et al. Cloning and characterization of a cDNA for rat CD30 homolog and chromosomal assignment of the genomic gene. Gene. 1996;182:155-62 pubmed
    ..2, and appeared to correspond to human 1p36, where human CD30 has been mapped. The identification and characterization of the rat counterpart of human CD30 will facilitate studies of the biological function of this molecule. ..
  69. Yokokura H, Terada O, Naito Y, Hidaka H. Isolation and comparison of rat cDNAs encoding Ca2+/calmodulin-dependent protein kinase I isoforms. Biochim Biophys Acta. 1997;1338:8-12 pubmed
    ..The obtained results support the idea that CaM kinase I exists as a set of isoforms. ..
  70. Nemoto T, Ohashi K, Akashi T, Johnson J, Hirokawa K. Overexpression of protein tyrosine kinases in human esophageal cancer. Pathobiology. 1997;65:195-203 pubmed
    ..In addition, we confirmed the expression of two isoforms of DDR/trkE/Cak in normal and cancerous esophagus. Our study suggests that DDR/trkE/Cak plays an important role in the regulation of proliferation of esophageal cancer. ..
  71. Yamaguchi T, Nakamura H, Kihara Y, Taguchi M, Yoshikawa H, Otsuki M. Long-term overexpression of membrane type-1 matrix metalloproteinase and matrix metalloproteinase-2 in oleic acid-induced pancreatitis in rats. Pancreas. 2002;24:348-56 pubmed
    ..Moreover, basement membranes disorganization in the sustentacula of acinar cells and duct epithelia seems to participate in continuous derangement of acinar cells and duct epithelium. ..
  72. Fukami H, Asakura T, Hirano H, Abe K, Shimomura K, Yamakawa T. Salicylic acid carboxyl methyltransferase induced in hairy root cultures of Atropa belladonna after treatment with exogeneously added salicylic acid. Plant Cell Physiol. 2002;43:1054-8 pubmed
    ..coli, and the recombinant AbSAMT1 showed SAMT activity. When A. belladonna hairy roots were exposed to a high concentration of SA, AbSAMT1 mRNA begins to be expressed 12 h after the exposure, and steady expression continued over 144 h...
  73. Ito A, Hashimoto T, Hirai M, Takeda T, Shuntoh H, Kuno T, et al. The complete primary structure of calcineurin A, a calmodulin binding protein homologous with protein phosphatases 1 and 2A. Biochem Biophys Res Commun. 1989;163:1492-7 pubmed
    ..These data suggest that the allosteric character of this chimeric enzyme is generated by gene fusion of two separate protein families. ..
  74. Kimura Y, Nakazawa M, Yamada M. Cloning and characterization of three isoforms of OS-9 cDNA and expression of the OS-9 gene in various human tumor cell lines. J Biochem. 1998;123:876-82 pubmed
    ..OS-9 expression decreased in differentiation-induced HL-60 cells. Possible involvement of the OS-9 gene in cell growth is discussed. ..
  75. Namekawa S, Hamada F, Sawado T, Ishii S, Nara T, Ishizaki T, et al. Dissociation of DNA polymerase alpha-primase complex during meiosis in Coprinus cinereus. Eur J Biochem. 2003;270:2137-46 pubmed
    ..These results suggest that the form of the DNA polymerase alpha-primase complex is altered during meiotic development...
  76. Harada H, Kitagawa M, Tanaka N, Yamamoto H, Harada K, Ishihara M, et al. Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2. Science. 1993;259:971-4 pubmed
    ..This transformed phenotype was reversed by concomitant overexpression of the IRF-1 gene. Thus, restrained cell growth depends on a balance between these two mutually antagonistic transcription factors. ..
  77. Watanabe Y, Yamamoto M. Schizosaccharomyces pombe pcr1+ encodes a CREB/ATF protein involved in regulation of gene expression for sexual development. Mol Cell Biol. 1996;16:704-11 pubmed
    ..Alternatively, its activity may be independent of PKA, and full induction of ste11 and fbp1 expression requires the function of Pcr1 in addition to elimination of the repression by PKA. ..
  78. Ochi K, Mori T, Toyama Y, Nakamura Y, Arakawa H. Identification of semaphorin3B as a direct target of p53. Neoplasia. 2002;4:82-7 pubmed
    ..These results suggest that Sema3B might play some role in regulating cell growth as a mediator of p53 tumor-suppressor activity. ..
  79. Kanayama H, Tanaka K, Aki M, Kagawa S, Miyaji H, Satoh M, et al. Changes in expressions of proteasome and ubiquitin genes in human renal cancer cells. Cancer Res. 1991;51:6677-85 pubmed
    ..These results suggest that the proteasome- and ubiquitin-mediated system is functionally involved in the cancerous state in human kidney. ..
  80. Fukunaga R, Seto Y, Mizushima S, Nagata S. Three different mRNAs encoding human granulocyte colony-stimulating factor receptor. Proc Natl Acad Sci U S A. 1990;87:8702-6 pubmed
    ..The third class of the G-CSF receptor contained a 27-amino acid insertion in the cytoplasmic domain and was highly expressed in placenta. ..
  81. Fujii G, Tashiro K, Emori Y, Saigo K, Tanaka K, Shiokawa K. Deduced primary structure of a Xenopus proteasome subunit XC3 and expression of its mRNA during early development. Biochem Biophys Res Commun. 1991;178:1233-9 pubmed
  82. Takagi S, Hirata T, Agata K, Mochii M, Eguchi G, Fujisawa H. The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors. Neuron. 1991;7:295-307 pubmed
    ..The mRNA for the A5 antigen was present in retinal ganglion cells and visual center neurons. Nonneuronal cells in the peripheral and central nervous systems did not express the mRNA for the A5 antigen. ..
  83. Tanaka Y, Tsujimura A, Fujita N, Isono S, Isono K. Cloning and analysis of an Escherichia coli operon containing the rpmF gene for ribosomal protein L32 and the gene for a 30-kilodalton protein. J Bacteriol. 1989;171:5707-12 pubmed
    ..The results suggest that rpmF forms an operon with the gene termed g30k which codes for a 30-kilodalton protein of unknown function. At least four transcripts were found to code for ribosomal protein L32. ..
  84. Tanaka T, Horio Y, Taketoshi M, Imamura I, Ando Yamamoto M, Kangawa K, et al. Molecular cloning and sequencing of a cDNA of rat dopa decarboxylase: partial amino acid homologies with other enzymes synthesizing catecholamines. Proc Natl Acad Sci U S A. 1989;86:8142-6 pubmed
    ..These results indicate that catecholamine biosynthetic enzymes are structurally related and suggest that their homologous domains are important for catechol-protein interactions. ..
  85. Tagawa M, Shirasawa T, Fujimura S, Sakiyama S. Identification of a rat protein tyrosine phosphatase gene preferentially expressed in the embryonal brain. Cell Mol Biol Res. 1994;40:627-31 pubmed
  86. Miyamoto K, Tatsumi S, Sonoda T, Yamamoto H, Minami H, Taketani Y, et al. Cloning and functional expression of a Na(+)-dependent phosphate co-transporter from human kidney: cDNA cloning and functional expression. Biochem J. 1995;305 ( Pt 1):81-5 pubmed
    ..These findings indicate that two high-affinity Na/P(i) cotransporters (NaP(i)-3 and NPT-1) are present in human kidney cortex. ..
  87. Matsuoka K, Taoka M, Satozawa N, Nakayama H, Ichimura T, Takahashi N, et al. A nuclear factor containing the leucine-rich repeats expressed in murine cerebellar neurons. Proc Natl Acad Sci U S A. 1994;91:9670-4 pubmed
    ..The structural characteristics, localization, and the stage- and cell type-specific expression suggest a potential role of LANP in a signal transduction pathway that directs differentiation of cerebellar neurons. ..
  88. Nakamura T, Asano M, Shindo Okada N, Nishimura S, Monden Y. Cloning of the RhoB gene from the mouse genome and characterization of its promoter region. Biochem Biophys Res Commun. 1996;226:688-94 pubmed
    ..Northern blotting analysis showed that the expression of the mouse rhoB gene was induced by serum, suggesting that expression of the rhoB gene might be controlled by some signal-responsive element(s). ..
  89. Matsumoto K, Ishii N, Yoshida S, Shiosaka S, Wanaka A, Tohyama M. Molecular cloning and distinct developmental expression pattern of spliced forms of a novel zinc finger gene wiz in the mouse cerebellum. Brain Res Mol Brain Res. 1998;61:179-89 pubmed
    ..The finding that two types of wiz transcripts (wizS and wizL) are expressed with different developmental patterns might indicate separate transcription functions in the cerebellar granule cells and the extracerebellar regions. ..
  90. Kakyo M, Unno M, Tokui T, Nakagomi R, Nishio T, Iwasashi H, et al. Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1. Gastroenterology. 1999;117:770-5 pubmed
    ..rlst-1 is a counterpart of human LST-1 and is one of the important transporters in rat liver for the clearance of bile acid. The expression of rlst-1 may be under feedback regulation of cholestasis by biliary obstruction and/or sepsis. ..
  91. Kobayashi M, Ikezoe T, Uemura Y, Takeuchi T, Ueno H, Ohtsuki Y, et al. Establishment of a novel small cell lung carcinoma cell line with specific recoverin expression from a patient with cancer-associated retinopathy. Lung Cancer. 2007;56:319-26 pubmed
    ..The present study demonstrates that human recoverin is expressed in SCLC cells cultured from an anti-recoverin antibody-negative patient with CAR. KK0206 might be important for further research on SCLC related retinopathy. ..
  92. Sakurai T, Yanagisawa M, Inoue A, Ryan U, Kimura S, Mitsui Y, et al. cDNA cloning, sequence analysis and tissue distribution of rat preproendothelin-1 mRNA. Biochem Biophys Res Commun. 1991;175:44-7 pubmed
    ..These findings suggest that ET-1 may play roles as a local mediator in multiple organs both within and outside the cardiovascular system in the rat. ..