Experts and Doctors on non steroidal anti inflammatory agents in Egypt


Locale: Egypt
Topic: non steroidal anti inflammatory agents

Top Publications

  1. Amin A. Spectrophotometric determination of piroxicam and tenoxicam in pharmaceutical formulations using alizarin. J Pharm Biomed Anal. 2002;29:729-36 pubmed
    ..9990 (n=10) with a relative standard deviation (R.S.D.) of </=1.2, for ten determinations of 1.0 microg ml(-1). The methods are successfully applied to the determination of piroxicam and tenoxicam in their pharmaceutical formulations. ..
  2. Mohamed H, Wadood H, Farghaly O. Potentiometric and spectrofluorimetric studies on complexation of tenoxicam with some metal ions. J Pharm Biomed Anal. 2002;28:819-26 pubmed
    ..Tenoxicam was determined by the proposed method in tablet, suppository and injection. The recovery percent ranged from 98.16 to 102.22%. The effect of 2-aminopyridine on the recovery of tenoxicam was also investigated. ..
  3. Mahmoud M, Zoheiry M, Nosseir M. Effect of combined chemotherapy and anti-inflammatory drugs on murine schistosomiasis. Arzneimittelforschung. 2002;52:294-301 pubmed
    ..So it can be concluded that in S. mansoni infection treatment with ibuprofen or naproxen is not preferable without treatment of schistosomiasis by using praziquantel. ..
  4. Taha E, Salama N, Fattah L. Spectrofluorimetric and spectrophotometric stability-indicating methods for determination of some oxicams using 7-chloro-4-nitrobenz-2-oxa-1,3-diazole (NBD-Cl). Chem Pharm Bull (Tokyo). 2006;54:653-8 pubmed
    ..The suggested procedures could be used for the determination of the above mentioned drugs in pure and dosage forms as well as in the presence of their degradation products. ..
  5. Abu Hashem A, Gouda M, Badria F. Synthesis of some new pyrimido[2',1':2,3]thiazolo[4,5-b]quinoxaline derivatives as anti-inflammatory and analgesic agents. Eur J Med Chem. 2010;45:1976-81 pubmed publisher
    ..These compounds were also screened for their analgesic and anti-inflammatory activities. Some of these compounds (3, 4, 9, 10 and 12-14) exhibited promising activities. ..
  6. Sheha M, Khedr A, Elsherief H. Biological and metabolic study of naproxen-propyphenazone mutual prodrug. Eur J Pharm Sci. 2002;17:121-30 pubmed
    ..The ester III was found to be less irritating to gastric mucosal membrane than the parent drugs. These results suggest that the synthesized prodrugs are characterized by better therapeutic index than the parent drugs. ..
  7. El Gibaly I, Safwat S, Ahmed M. Microencapsulation of ketoprofen using w/o/w complex emulsion technique. J Microencapsul. 1996;13:67-87 pubmed
    ..These films exhibited sustained release of the drug (t0 center dot 5; 58-146 h). Release rates were found to agree with the Baker and Lonsdale model, previously suggested for ketoprofen release from CAB-PS microcapsules. ..
  8. Hegazy S, El Bedewy M. Effect of probiotics on pro-inflammatory cytokines and NF-kappaB activation in ulcerative colitis. World J Gastroenterol. 2010;16:4145-51 pubmed
    ..05). Oral supplementation with probiotics could be helpful in maintaining remission and preventing relapse of UC. ..
  9. Tuorkey M, Karolin K. Anti-ulcer activity of curcumin on experimental gastric ulcer in rats and its effect on oxidative stress/antioxidant, IL-6 and enzyme activities. Biomed Environ Sci. 2009;22:488-95 pubmed publisher
    ..Curcumin appears to have a propitious protective effect against gastric ulcer development. ..

More Information


  1. Shaaban M, Saleh T, Mayhoub A, Mansour A, Farag A. Synthesis and analgesic/anti-inflammatory evaluation of fused heterocyclic ring systems incorporating phenylsulfonyl moiety. Bioorg Med Chem. 2008;16:6344-52 pubmed publisher
  2. Sayed M, Abolyosr A, Abdalla M, El Azab A. Efficacy of tamsulosin in medical expulsive therapy for distal ureteral calculi. Scand J Urol Nephrol. 2008;42:59-62 pubmed
    ..Our study reveals the efficacy of tamsulosin for the treatment of distal ureteral stones. Tamsulosin should be added to the standard medical approach for treating these stones. ..
  3. Mohamed Hussein A, Mohamed N, Ibrahim M. Changes in pulmonary function in patients with ulcerative colitis. Respir Med. 2007;101:977-82 pubmed
    ..The impairment in active disease exceeded that during the remission. Early recognition is important, as they can be strikingly steroid responsive. ..
  4. Kenawi I, Barsoum B, Youssef M. Drug-drug interaction between diclofenac, cetirizine and ranitidine. J Pharm Biomed Anal. 2005;37:655-61 pubmed
    ..The 1,2,3-substitutions in the benzene ring of 1 in the mixture appear at 1161.1 cm(-1). The (1)H NMR of the mixed drugs shows singlet, triplet and multiplet proton signals due to the same effect. ..
  5. Abdin A, Baalash A, Hamooda H. Effects of rosiglitazone and aspirin on experimental model of induced type 2 diabetes in rats: focus on insulin resistance and inflammatory markers. J Diabetes Complications. 2010;24:168-78 pubmed publisher
  6. Abdel Azeem A, Abdel Hafez A, El Karamany G, Farag H. Chlorzoxazone esters of some non-steroidal anti-inflammatory (NSAI) carboxylic acids as mutual prodrugs: design, synthesis, pharmacological investigations and docking studies. Bioorg Med Chem. 2009;17:3665-70 pubmed publisher
    ..In addition, docking of the mutual ester prodrugs (6-8) into COX-2 active site was conducted in order to predict the affinity and orientation of these prodrugs at the enzyme active site...
  7. Morsy M, Ashour O, Amin E, Rofaeil R. Gastroprotective effects of telmisartan on experimentally-induced gastric ulcers in rats. Pharmazie. 2009;64:590-4 pubmed
    ..Also, the greater gastroprotection afforded by telmisartan compared to candesartan could be partly ascribed to its PPARgamma-inducing property. ..
  8. Sayed A, Morcos M. Thymoquinone decreases AGE-induced NF-kappaB activation in proximal tubular epithelial cells. Phytother Res. 2007;21:898-9 pubmed
    ..A significant reduction of AGE-induced NF-kappaB-activation and Il-6 expression was observed. This points to potential antioxidative qualities of TQ. ..
  9. Ismail S, Mowafi H. Preoperative peritonsillar lornoxicam infiltration is not superior to intravenous lornoxicam for pain relief following tonsillectomy in adults. Eur J Anaesthesiol. 2010;27:807-11 pubmed publisher
    ..Peritonsillar infiltration or i.v. lornoxicam enhanced postoperative analgesia after tonsillectomy in adults. However, the analgesic efficacy of locally applied lornoxicam is not superior to the i.v. administration. ..