Experts and Doctors on nervous system diseases in United States

Summary

Locale: United States
Topic: nervous system diseases

Top Publications

  1. Iuorno J, Kolostyak K, Mejico L. Therapies with potential toxicity of neuro-ophthalmic interest. Curr Opin Ophthalmol. 2003;14:339-43 pubmed
    ..Appropriate management requires prompt recognition of these associations. Practitioners should be familiar with these neuro-ophthalmic manifestations because they may present in the course of daily practice. ..
  2. Espinosa P, Choudry B, Wilbourn R, Espinosa P, Vaishnav A. Pituitary apoplexy: a neurological emergency case report. J Ky Med Assoc. 2007;105:538-40 pubmed
    ..Rapid recognition, prompt management, and neurosurgical referral was lifesaving in this patient. ..
  3. Berger J, Weaver A, Greenlee J, Wahlen G. Neurologic consequences of autoimmune polyglandular syndrome type 1. Neurology. 2008;70:2248-51 pubmed publisher
    ..The neurologic complications of this disorder have not been well characterized...
  4. Farooqui A, Farooqui T, Panza F, Frisardi V. Metabolic syndrome as a risk factor for neurological disorders. Cell Mol Life Sci. 2012;69:741-62 pubmed publisher
  5. Backonja M. Use of anticonvulsants for treatment of neuropathic pain. Neurology. 2002;59:S14-7 pubmed
    ..Evidence supporting the efficacy of anticonvulsants in treatment of such pain is evolving. Additional clinical trials should provide information that will better define their role in neuropathic pain. ..
  6. Kumar N, Low P. Myeloneuropathy and anemia due to copper malabsorption. J Neurol. 2004;251:747-9 pubmed
    ..The limited literature on neurological manifestations of acquired copper deficiency suggests that the clinical presentation resembles the myeloneuropathy seen with vitamin B12 deficiency. ..
  7. Fan L, Pang Y, Lin S, Tien L, Ma T, Rhodes P, et al. Minocycline reduces lipopolysaccharide-induced neurological dysfunction and brain injury in the neonatal rat. J Neurosci Res. 2005;82:71-82 pubmed
    ..These results suggest that inhibition of microglial activation by minocycline may have long-term protective effects in the neonatal brain on infection-induced brain injury and associated neurologic dysfunction in the rat. ..
  8. Rodriguez R, Fernandez H, Haq I, Okun M. Pearls in patient selection for deep brain stimulation. Neurologist. 2007;13:253-60 pubmed
    ..These areas must be adequately addressed prior to any surgical procedure. ..
  9. Kilburn K. Neurobehavioral and pulmonary impairment in 105 adults with indoor exposure to molds compared to 100 exposed to chemicals. Toxicol Ind Health. 2009;25:681-92 pubmed publisher
    ..Vital capacities were reduced in both groups. Neurobehavioral and pulmonary impairments associated with exposures to indoor molds and mycotoxins were not different from those with various chemical exposures. ..

More Information

Publications140 found, 100 shown here

  1. Barnes G, Slevin J. Ionotropic glutamate receptor biology: effect on synaptic connectivity and function in neurological disease. Curr Med Chem. 2003;10:2059-72 pubmed
    ..Identification of therapeutic pharmacologic targets and development of antagonists specific to the disease process remain central themes in epilepsy and stroke research. ..
  2. Souayah N, Hassan A, Krivitskaya N, Lee H, Michas Martin A, Cruz A, et al. Neurosarcoidosis presenting as an anterior horn syndrome. J Neuroimmunol. 2010;225:132-6 pubmed publisher
    ..We hypothesize that meningeal granulomatous inflammation compressed the exiting anterior roots which resulted in motor dysfunction with preservation of peripheral sensory fibers. ..
  3. Stoffel J, McGuire E. Outcome of urethral closure in patients with neurologic impairment and complete urethral destruction. Neurourol Urodyn. 2006;25:19-22 pubmed
    ..Most have serious co-mobidities and a single operation does not usually solve all the problems. Persistence does almost always result in continence. ..
  4. Wu J, Ricker M, Muench J. Copper deficiency as cause of unexplained hematologic and neurologic deficits in patient with prior gastrointestinal surgery. J Am Board Fam Med. 2006;19:191-4 pubmed
    ..We report the case of a 51-year-old woman admitted for nonspecific neurologic symptoms ultimately found to be due to copper malabsorption. ..
  5. Owens K, Glassman S, Howard J, Djurasovic M, Witten J, Carreon L. Perioperative complications with rhBMP-2 in transforaminal lumbar interbody fusion. Eur Spine J. 2011;20:612-7 pubmed publisher
    ..It will be necessary to weigh this incidence of complications against the complication rate associated with ICBG harvest and any differential benefit in obtaining a solid arthrodesis. ..
  6. Park K, Pepine C. Pathophysiologic mechanisms linking impaired cardiovascular health and neurologic dysfunction: the year in review. Cleve Clin J Med. 2010;77 Suppl 3:S40-5 pubmed publisher
  7. Yalvac M, Yarat A, Mercan D, Rizvanov A, Palotás A, Sahin F. Characterization of the secretome of human tooth germ stem cells (hTGSCs) reveals neuro-protection by fine-tuning micro-environment. Brain Behav Immun. 2013;32:122-30 pubmed publisher
    ..This report reveals for the first time that the neuro-protective secretome of hTGSCs and the micro-environment of cells have a mutual and dynamic impact on one another. ..
  8. Potluri K, Holt D, Hou S. Neurologic complications in renal transplantation. Handb Clin Neurol. 2014;121:1245-55 pubmed publisher
    ..The prevalence of stroke is reported to be around 8% with age>40 years, diabetic nephropathy as the underlying cause of end-stage kidney disease, and peripheral vascular disease being the strongest predictors. ..
  9. Friedman J, Goerss S, Meyer F, Piepgras D, Pichelmann M, McIver J, et al. Volumetric quantification of Fisher Grade 3 aneurysmal subarachnoid hemorrhage: a novel method to predict symptomatic vasospasm on admission computerized tomography scans. J Neurosurg. 2002;97:401-7 pubmed
    ..Prospective application of software-based volumetric quantification of cisternal SAH may predict which patients will develop DIND. ..
  10. Sellon D, Knowles D, Greiner E, Long M, Hines M, Hochstatter T, et al. Depletion of natural killer cells does not result in neurologic disease due to Sarcocystis neurona in mice with severe combined immunodeficiency. J Parasitol. 2004;90:782-8 pubmed
    ..These results indicate that IFN-gamma mediates protection from neurologic disease in SCID mice. Protective levels of IFN-gamma may originate from a low number of nondepleted NK cells or from a non-T cell, non-NK cell population...
  11. Farooqui A, Horrocks L, Farooqui T. Interactions between neural membrane glycerophospholipid and sphingolipid mediators: a recipe for neural cell survival or suicide. J Neurosci Res. 2007;85:1834-50 pubmed
  12. Jones L, McDonald D, Borum P. Acylcarnitines: role in brain. Prog Lipid Res. 2010;49:61-75 pubmed publisher
    ..In summary, carnitine is not merely a cofactor in beta-oxidation, but rather it has many known and yet to be discovered functions in physiology. ..
  13. Zinchuk A, Flanagan E, Tubridy N, Miller W, McCullough L. Attitudes of US medical trainees towards neurology education: "Neurophobia" - a global issue. BMC Med Educ. 2010;10:49 pubmed publisher
    ..Studies are needed to quantify the effect of these interventions on confidence of trainees when dealing with patients presenting with neurological complaints. ..
  14. Zlokovic B, Griffin J. Cytoprotective protein C pathways and implications for stroke and neurological disorders. Trends Neurosci. 2011;34:198-209 pubmed publisher
  15. Dasgupta T, Ladd A. The importance of CELF control: molecular and biological roles of the CUG-BP, Elav-like family of RNA-binding proteins. Wiley Interdiscip Rev RNA. 2012;3:104-21 pubmed publisher
    ..Dysregulation of CELF-mediated programs has been implicated in the pathogenesis of human diseases affecting the heart, skeletal muscles, and nervous system. ..
  16. Janigro D. Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier. Epilepsia. 2012;53 Suppl 1:26-34 pubmed publisher
  17. Hota P, Buck M. Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions. Cell Mol Life Sci. 2012;69:3765-805 pubmed publisher
    ..The structural information is helping the plexin field to focus on key questions at the protein structural, cellular, as well as organism level that collaboratoria of investigations are likely to answer. ..
  18. Maher C, Piepgras D, Brown R, Friedman J, Pollock B. Cerebrovascular manifestations in 321 cases of hereditary hemorrhagic telangiectasia. Stroke. 2001;32:877-82 pubmed
    ..By comparison, pulmonary arteriovenous fistulae are a much more frequent cause of neurological symptoms in this population. ..
  19. Fonteh A, Harrington R, Huhmer A, Biringer R, Riggins J, Harrington M. Identification of disease markers in human cerebrospinal fluid using lipidomic and proteomic methods. Dis Markers. 2006;22:39-64 pubmed
    ..Combining lipidomics and proteomics will enhance existing knowledge of disease pathology and increase the likelihood of discovering specific markers and biochemical mechanisms of brain diseases. ..
  20. Silvers J, Aksenov M, Aksenova M, Beckley J, Olton P, Mactutus C, et al. Dopaminergic marker proteins in the substantia nigra of human immunodeficiency virus type 1-infected brains. J Neurovirol. 2006;12:140-5 pubmed
    ..These results suggest that decreases in TH, the rate-limiting enzyme of dopamine synthesis, may be a factor in the neurological manifestations of HIV infection. ..
  21. Judson M. Extrapulmonary sarcoidosis. Semin Respir Crit Care Med. 2007;28:83-101 pubmed
    ..This article reviews the clinical presentation and therapy of extrapulmonary sarcoidosis. ..
  22. Allen G. Risk factors for development of neurologic disease after experimental exposure to equine herpesvirus-1 in horses. Am J Vet Res. 2008;69:1595-600 pubmed publisher
    ..The importance of achieving immunity related to high concentrations of vaccine-induced CTLPs in horses at high risk for exposure to neuropathogenic strains of EHV-1 is indicated. ..
  23. Smith K, Allen G, Branscum A, Frank Cook R, Vickers M, Timoney P, et al. The increased prevalence of neuropathogenic strains of EHV-1 in equine abortions. Vet Microbiol. 2010;141:5-11 pubmed publisher
    ..This finding clearly suggests that additional research is required before the genetic basis of the neuropathogenic phenotype in EHV-1 is fully understood. ..
  24. Dowling N, Tomaszewski Farias S, Reed B, Sonnen J, Strauss M, Schneider J, et al. Neuropathological associates of multiple cognitive functions in two community-based cohorts of older adults. J Int Neuropsychol Soc. 2011;17:602-14 pubmed
    ..Results show that cognition is complexly determined by multiple disease substrates. Neuropathological variables and brain weight contributed approximately a third to half of the explained variance in different cognitive domains. ..
  25. Miwa J, Freedman R, Lester H. Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses. Neuron. 2011;70:20-33 pubmed publisher
    ..We also discuss how these contemporary advances can motivate attempts to exploit nicotinic systems therapeutically in Parkinson's disease, cognitive decline, epilepsy, and schizophrenia. ..
  26. Dugger B, Murray M, Boeve B, Parisi J, Benarroch E, Ferman T, et al. Neuropathological analysis of brainstem cholinergic and catecholaminergic nuclei in relation to rapid eye movement (REM) sleep behaviour disorder. Neuropathol Appl Neurobiol. 2012;38:142-52 pubmed publisher
    ..The mechanism of selective ?-synuclein-mediated neuronal loss in these nuclei remains to be determined. ..
  27. Khaing Z, Schmidt C. Advances in natural biomaterials for nerve tissue repair. Neurosci Lett. 2012;519:103-14 pubmed publisher
    ..In addition, newly developed advanced fabrication techniques to further develop the next generation natural biomaterials-based therapeutic devices are discussed. ..
  28. Johnson R, Mitchell G. Common mechanisms of compensatory respiratory plasticity in spinal neurological disorders. Respir Physiol Neurobiol. 2013;189:419-28 pubmed publisher
    ..Through this contrast, we hope to understand the multilayered strategies used to "fight" for adequate breathing in the face of mounting pathology. ..
  29. Farooqui A, Ong W, Horrocks L. Plasmalogens, docosahexaenoic acid and neurological disorders. Adv Exp Med Biol. 2003;544:335-54 pubmed
  30. Yasuhara T, Hara K, Maki M, Masuda T, Sanberg C, Sanberg P, et al. Dietary supplementation exerts neuroprotective effects in ischemic stroke model. Rejuvenation Res. 2008;11:201-14 pubmed publisher
    ..These data demonstrate the remarkable neuroprotective effects of NT-020 when given prior to stroke, possibly acting via its neurogenic potential. ..
  31. Stump D, Beck M, Radovsky A, Garman R, Freshwater L, Sheets L, et al. Developmental neurotoxicity study of dietary bisphenol A in Sprague-Dawley rats. Toxicol Sci. 2010;115:167-82 pubmed publisher
    ..There was no evidence that BPA is a developmental neurotoxicant in rats, and the NOAEL for developmental neurotoxicity was 2250 ppm, the highest dose tested (164 and 410 mg/kg/day during gestation and lactation, respectively). ..
  32. Sakamoto K, Karelina K, Obrietan K. CREB: a multifaceted regulator of neuronal plasticity and protection. J Neurochem. 2011;116:1-9 pubmed publisher
    ..We also discuss work showing that CREB is a critical component of the neuroprotective transcriptional network, and data indicating that CREB dysregulation contributes to an array of neuropathological conditions. ..
  33. Bodnar R. Endogenous opiates and behavior: 2012. Peptides. 2013;50:55-95 pubmed publisher
  34. Kelly M, Lenke L, Godzik J, Pellisé F, Shaffrey C, Smith J, et al. Retrospective analysis underestimates neurological deficits in complex spinal deformity surgery: a Scoli-RISK-1 Study. J Neurosurg Spine. 2017;27:68-73 pubmed publisher
    ..These findings validate concerns regarding retrospective cohort studies and confirm the need for and value of carefully designed prospective, observational cohort studies in ASD. ..
  35. OCHOA J, Campero M, Serra J, Bostock H. Hyperexcitable polymodal and insensitive nociceptors in painful human neuropathy. Muscle Nerve. 2005;32:459-72 pubmed
    ..This similarity, and the striking heat dependence of the spontaneous pain, suggest that a common feature may be altered expression or modulation of vanilloid 1 receptor, provoking abnormal nociceptor discharges. ..
  36. Pallotto E, Kilbride H. Perinatal outcome and later implications of intrauterine growth restriction. Clin Obstet Gynecol. 2006;49:257-69 pubmed
    ..Morbidities associated with preterm delivery appear to be additive to those associated with fetal growth restriction so IUGR, preterm infants may be at great risk for poor neurodevelopmental outcome. ..
  37. Hall E, Traystman R. Role of animal studies in the design of clinical trials. Front Neurol Neurosci. 2009;25:10-33 pubmed publisher
  38. Nozaki K, Silver R, Stickler D, Abou Fayssal N, Giglio P, Kamen D, et al. Neurological deficits during treatment with tumor necrosis factor-alpha antagonists. Am J Med Sci. 2011;342:352-5 pubmed publisher
    ..Determining if the relationship between the neurological deficits and TNF-? antagonist therapy is causal can be challenging and can impact patient care. ..
  39. Pollock J. Transient neurologic symptoms: etiology, risk factors, and management. Reg Anesth Pain Med. 2002;27:581-6 pubmed
  40. Koide M, Nystoriak M, Krishnamoorthy G, O Connor K, Bonev A, Nelson M, et al. Reduced Ca2+ spark activity after subarachnoid hemorrhage disables BK channel control of cerebral artery tone. J Cereb Blood Flow Metab. 2011;31:3-16 pubmed publisher
    ..This phenomenon may contribute to decreased cerebral blood flow and poor outcome after aneurysmal SAH. ..
  41. McKay W. Neurophysiological characterization of the 'new anatomy' and motor control that results from neurological injury or disease. Clin Neurol Neurosurg. 2012;114:447-54 pubmed publisher
    ..Measured through multiple-muscle recordings of selected motor-task performance, these domains can be useful in quantifying the severity of CNS damage and changes achieved through recovery or treatment. ..
  42. Spencer P, Kisby G, Ludolph A. Slow toxins, biologic markers, and long-latency neurodegenerative disease in the western Pacific region. Neurology. 1991;41:62-6; discussion 66-8 pubmed
    ..This paper explores the possible relationship between tumorigenesis and long-latency neurotoxicity, and discusses possible biologic markers of cycad exposure and subclinical neurodegenerative disease...
  43. Tani M, Fuentes M, Peterson J, Trapp B, Durham S, Loy J, et al. Neutrophil infiltration, glial reaction, and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes. J Clin Invest. 1996;98:529-39 pubmed
    ..Late-onset neurological symptoms in MBP-N51/KC mice may indicate unanticipated consequences of CNS chemokine expression. ..
  44. Berger J, Fannin M. The "bedsheet" Babinski. South Med J. 2002;95:1178-9 pubmed
    ..Although typically elicited by stroking the plantar surface of the foot with a firm object, other means of obtaining the response have been described...
  45. Judson M. Sarcoidosis: clinical presentation, diagnosis, and approach to treatment. Am J Med Sci. 2008;335:26-33 pubmed publisher
    ..Sarcoidosis may remit spontaneously or remain stable. Therefore, therapy is not mandated for the disease. This report reviews the clinical presentation, diagnostic approach, and treatment of sarcoidosis. ..
  46. Bousquet Moore D, Mains R, Eipper B. Peptidylgycine ?-amidating monooxygenase and copper: a gene-nutrient interaction critical to nervous system function. J Neurosci Res. 2010;88:2535-45 pubmed publisher
  47. Titsworth W, Hester J, Correia T, Reed R, Williams M, Guin P, et al. Reduction of catheter-associated urinary tract infections among patients in a neurological intensive care unit: a single institution's success. J Neurosurg. 2012;116:911-20 pubmed publisher
  48. Westmark C, Westmark P, Malter J. Soy-based diet exacerbates seizures in mouse models of neurological disease. J Alzheimers Dis. 2013;33:797-805 pubmed publisher
    ..Thus, the soy isoflavone daidzein recapitulated seizure induction in vivo and altered A?PP expression in vitro. These results have important implications for individuals on soy-based diets as well as for rodent model research. ..
  49. Seal R, Amara S. Excitatory amino acid transporters: a family in flux. Annu Rev Pharmacol Toxicol. 1999;39:431-56 pubmed
    ..This review summarizes current knowledge of the structural and functional diversity of excitatory amino acid transporters and explores how they might serve as targets for drug design. ..
  50. Lee Y, McKinnon P. Responding to DNA double strand breaks in the nervous system. Neuroscience. 2007;145:1365-74 pubmed
    ..Thus, there are distinct requirements for each DNA DSB repair pathway during neural development, which have important implications for understanding diseases of the nervous system...
  51. Hu X, Fan Q, Hou H, Yan R. Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling. J Neurochem. 2016;136:234-49 pubmed publisher
    ..The dependence of Nrg on the cleavage by BACE1 is best manifested by disrupting the critical role of Nrg in the control of axonal myelination, schizophrenic behaviors as well as the formation and maintenance of muscle spindles. ..
  52. Ney J, Johnson B, Knabel T, Craft K, Kaufman J. Neurologist ambulatory care, health care utilization, and costs in a large commercial dataset. Neurology. 2016;86:367-74 pubmed publisher
    ..Neurologist involvement with care is associated with greater unadjusted allowed payments, but fewer adverse events and less acute care utilization. ..
  53. Anji A, Kumari M. Guardian of Genetic Messenger-RNA-Binding Proteins. Biomolecules. 2016;6:4 pubmed publisher
    ..We further discuss the conventional methods and newer techniques that are employed to identify RNA-binding proteins. ..
  54. Nadeau S, Wu S. CIMT as a behavioral engine in research on physiological adjuvants to neurorehabilitation: the challenge of merging animal and human research. NeuroRehabilitation. 2006;21:107-30 pubmed
    ..We consider modifications in current approaches that might more efficiently advance neurorehabilitation science. ..
  55. Won J, Singh A, Singh I. Lactosylceramide: a lipid second messenger in neuroinflammatory disease. J Neurochem. 2007;103 Suppl 1:180-91 pubmed
  56. Thayer J, Sternberg E. Neural aspects of immunomodulation: focus on the vagus nerve. Brain Behav Immun. 2010;24:1223-8 pubmed publisher
    ..Then we will provide an overview of what is known from both animal and human studies including neuroimaging and clinical studies. Finally, we will discuss some of the challenges and opportunities in this exciting area of investigation. ..
  57. Obermeier B, Daneman R, Ransohoff R. Development, maintenance and disruption of the blood-brain barrier. Nat Med. 2013;19:1584-96 pubmed publisher
    ..We then discuss how BBB disruption can cause or contribute to neurological disease. Finally, we examine how this knowledge can be used to explore new possibilities for BBB repair. ..
  58. Wen R, Banik B, Pathak R, Kumar A, Kolishetti N, Dhar S. Nanotechnology inspired tools for mitochondrial dysfunction related diseases. Adv Drug Deliv Rev. 2016;99:52-69 pubmed publisher
    ..In this review, we present an extensive coverage of possible therapeutic targets in different compartments of mitochondria for cancer, cardiovascular, and mitochondrial dysfunction related diseases. ..
  59. Cotten C, Goldstein R, McDonald S, Goldberg R, Salhab W, Carlo W, et al. Apolipoprotein E genotype and outcome in infants with hypoxic-ischemic encephalopathy. Pediatr Res. 2014;75:424-30 pubmed publisher
    ..None of the differences were statistically significant. CP prevalence was also similar among genotype groups. Disability was not associated with the APOE genotype in this cohort of HIE survivors. ..
  60. Levine S, Wetzel D, Eilert A. Neuropathology of twitcher mice: examination by histochemistry, immunohistochemistry, lectin histochemistry and Fourier transform infrared microspectroscopy. Int J Dev Neurosci. 1994;12:275-88 pubmed
  61. Titsworth W, Hester J, Correia T, Reed R, Guin P, Archibald L, et al. The effect of increased mobility on morbidity in the neurointensive care unit. J Neurosurg. 2012;116:1379-88 pubmed publisher
    ..Among neurointensive care unit patients, increased mobility can be achieved quickly and safely with associated reductions in LOS and hospital-acquired infections using the PUMP Plus program. ..
  62. Elmer J, Torres C, Aufderheide T, Austin M, Callaway C, Golan E, et al. Association of early withdrawal of life-sustaining therapy for perceived neurological prognosis with mortality after cardiac arrest. Resuscitation. 2016;102:127-35 pubmed publisher
    ..After OHCA, death following WLST-N<72 may be common and is potentially avoidable. Reducing WLST-N<72 has national public health implications and may afford an opportunity to decrease mortality after OHCA. ..
  63. Gold B, Villafranca J. Neuroimmunophilin ligands: the development of novel neuroregenerative/ neuroprotective compounds. Curr Top Med Chem. 2003;3:1368-75 pubmed
    ..We suggest that components of steroid receptor complexes are novel targets for the design of neuroregenerative/neuroprotective drugs. ..
  64. Sun J, Hu H, Ren X, Simpkins J. Tert-butylhydroquinone compromises survival in murine experimental stroke. Neurotoxicol Teratol. 2016;54:15-21 pubmed publisher
    ..These data indicate that tBHQ-exacerbated stroke damage might due to the compromised BBB permeability in permanent stroke. ..
  65. McJunkin J, de los Reyes E, Irazuzta J, Caceres M, Khan R, Minnich L, et al. La Crosse encephalitis in children. N Engl J Med. 2001;344:801-7 pubmed
    ..La Crosse encephalitis is a mosquito-borne disease that can be mistaken for herpes simplex encephalitis. It has been reported in 28 states but may be underrecognized...
  66. Vernino S, Lennon V. Autoantibody profiles and neurological correlations of thymoma. Clin Cancer Res. 2004;10:7270-5 pubmed
    ..Serological evaluation of a patient's profile of neuronal and muscle autoantibodies may aid in preoperative identification of an indeterminate mediastinal mass. ..
  67. Huang Z. Molecular regulation of neuronal migration during neocortical development. Mol Cell Neurosci. 2009;42:11-22 pubmed publisher
    ..These findings have not only enhanced our understanding of normal neuron migration but also revealed insights into the etiologies of several neurological diseases where these processes go awry. ..
  68. Rahman M, Bidari S, Quisling R, Friedman W. Spontaneous intracranial hypotension: dilemmas in diagnosis. Neurosurgery. 2011;69:4-14; discussion 14 pubmed publisher
    ..Here, based on a comprehensive literature review, we describe the epidemiology, presentation, diagnostic workup and treatment of SIH. ..
  69. Struble R, Cady C, Nathan B, McAsey M. Apolipoprotein E may be a critical factor in hormone therapy neuroprotection. Front Biosci. 2008;13:5387-405 pubmed
    ..Future studies of HT should evaluate the effects of apoE genotype and production estradiol on neuroprotection. ..
  70. Bidinost C, Matsumoto M, Chung D, Salem N, Zhang K, Stockton D, et al. Heterozygous and homozygous mutations in PITX3 in a large Lebanese family with posterior polar cataracts and neurodevelopmental abnormalities. Invest Ophthalmol Vis Sci. 2006;47:1274-80 pubmed
    ..Also studied were two siblings who were homozygous for the PITX3 mutation who had microphthalmia and significant neurologic impairment...
  71. Vogelbaum M, Sampson J, Kunwar S, Chang S, Shaffrey M, Asher A, et al. Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results. Neurosurgery. 2007;61:1031-7; discussion 1037-8 pubmed
    ..CB (0.5 microg/mL) administered via convection-enhanced delivery before standard radiochemotherapy seems to be well tolerated in adults with newly diagnosed malignant gliomas. Further clinical study assessment is warranted. ..
  72. Hsiao Y, Tong Z, Westfall J, Ault J, Page McCaw P, Ferland R. Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking. Hum Mol Genet. 2009;18:3926-41 pubmed publisher
    ..Overall, our data indicate that the distribution and functioning of Rab8a is regulated by Ahi1, not only affecting cilium formation, but also vesicle transport...
  73. Yao C, El Khoury R, Wang W, Byrd T, Pehek E, Thacker C, et al. LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease. Neurobiol Dis. 2010;40:73-81 pubmed publisher
    ..These invertebrate models will be useful for studying pathogenesis of PD and for development of potential therapeutics for the disease. ..
  74. Neuwelt E, Bauer B, Fahlke C, Fricker G, Iadecola C, Janigro D, et al. Engaging neuroscience to advance translational research in brain barrier biology. Nat Rev Neurosci. 2011;12:169-82 pubmed publisher
  75. McIntyre C, Foutz T. Computational modeling of deep brain stimulation. Handb Clin Neurol. 2013;116:55-61 pubmed publisher
  76. Harrington M, Aebersold R, Martin B, Merril C, Hood L. Identification of a brain-specific human cerebrospinal fluid glycoprotein, beta-trace protein. Appl Theor Electrophor. 1993;3:229-34 pubmed
    ..Proteins of different mass and charge from beta-trace protein were clearly immunostained in samples of eight tissues.(ABSTRACT TRUNCATED AT 250 WORDS) ..
  77. Malley L, Hansen J, Everds N, Warheit D. 4-week inhalation toxicity study with a mixture of dichloroethylene and perfluorobutylethylene in rats. Inhal Toxicol. 2002;14:773-87 pubmed
    ..Under the conditions of the study, the no-observed-effect level (NOEL) was 400 ppm in males and females based on clinical signs of toxicity during exposure to 2000 or 8000 ppm. ..
  78. Kent P, Michet C, Luthra H. Relapsing polychondritis. Curr Opin Rheumatol. 2004;16:56-61 pubmed
    ..This article summarizes important aspects of the disease with a focus on recent information regarding clinical manifestations, disease associations, pathogenesis, and advances in therapeutics...
  79. Marra C, Maxwell C, Tantalo L, Eaton M, Rompalo A, Raines C, et al. Normalization of cerebrospinal fluid abnormalities after neurosyphilis therapy: does HIV status matter?. Clin Infect Dis. 2004;38:1001-6 pubmed
    ..Future studies should address whether more intensive therapy for neurosyphilis is warranted in HIV-infected individuals...
  80. Fox C, Ramig L, Ciucci M, Sapir S, McFarland D, Farley B. The science and practice of LSVT/LOUD: neural plasticity-principled approach to treating individuals with Parkinson disease and other neurological disorders. Semin Speech Lang. 2006;27:283-99 pubmed
  81. Markowski V. Report of the 26th annual meeting of the Behavioral Toxicology Society. Neurotoxicol Teratol. 2007;29:586-7 pubmed
  82. Wortzel H, Oster T, Anderson C, Arciniegas D. Pathological laughing and crying : epidemiology, pathophysiology and treatment. CNS Drugs. 2008;22:531-45 pubmed
  83. Kim C, Waldman I, Blakely R, Kim K. Functional gene variation in the human norepinephrine transporter: association with attention deficit hyperactivity disorder. Ann N Y Acad Sci. 2008;1129:256-60 pubmed publisher
    ..Moreover, we observed a significant association of the -3081(T) variant with ADHD. Altered transcription of SLC6A2 may therefore represent a novel risk factor for the development of ADHD. ..
  84. Pasternak J, Lanier W. Is nitrous oxide use appropriate in neurosurgical and neurologically at-risk patients?. Curr Opin Anaesthesiol. 2010;23:544-50 pubmed publisher
    ..Except in a few specific circumstances, there exists no conclusive evidence to support the dogmatic avoidance of nitrous oxide in neurosurgical patients. ..
  85. Nakagawa S, Castro V, Toborek M. Infection of human pericytes by HIV-1 disrupts the integrity of the blood-brain barrier. J Cell Mol Med. 2012;16:2950-7 pubmed publisher
    ..These findings indicate that human brain pericytes can be infected with HIV-1 and suggest that infected pericytes are involved in the progression of HIV-1-induced CNS damage. ..
  86. Oluigbo C, Salma A, Rezai A. Deep brain stimulation for neurological disorders. IEEE Rev Biomed Eng. 2012;5:88-99 pubmed publisher
    ..The clinical results from studies on DBS show that it has great potential making it one of most promising fields which could be used to address challenging neurological problems. ..
  87. Backonja M, Attal N, Baron R, Bouhassira D, Drangholt M, Dyck P, et al. Value of quantitative sensory testing in neurological and pain disorders: NeuPSIG consensus. Pain. 2013;154:1807-19 pubmed publisher
    ..When appropriate standards, as discussed here, are applied, QST can provide important and unique information about the functional status of somatosensory system, which would be complementary to already existing clinical methods. ..
  88. Melian E. Radiation therapy in neurologic disease. Handb Clin Neurol. 2014;121:1181-98 pubmed publisher
    ..In addition we review the more commonly seen side effects and complications of treatment which may be seen by the neurologist. ..
  89. Heroux A, Pamboukian S. Neurologic aspects of heart transplantation. Handb Clin Neurol. 2014;121:1229-36 pubmed publisher
    ..In children, seizures are the most common neurologic complication, although other neurologic complication rates are comparable. ..
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