Experts and Doctors on nerve tissue proteins in Germany


Locale: Germany
Topic: nerve tissue proteins

Top Publications

  1. Schneider T, Reiter C, Eule E, Bader B, Lichte B, Nie Z, et al. Restricted expression of the irreC-rst protein is required for normal axonal projections of columnar visual neurons. Neuron. 1995;15:259-71 pubmed
    ..Epigenesis of the phenotypes can be explained partially on the bases of homophilic irreC-rst interactions. ..
  2. Schroder S, Morris S, Knorr R, Plessmann U, Weber K, Nguyen G, et al. Primary structure of the neuronal clathrin-associated protein auxilin and its expression in bacteria. Eur J Biochem. 1995;228:297-304 pubmed
    ..Recombinant auxilin expressed in and purified from bacteria by affinity chromatography is functional with respect to clathrin binding. ..
  3. Schnutgen F, Borchers T, Muller T, Spener F. Heterologous expression and characterisation of mouse brain fatty acid binding protein. Biol Chem Hoppe Seyler. 1996;377:211-5 pubmed
    ..By Western blotting using affinity purified rabbit antibodies raised against the recombinant B-FABP it was demonstrated that in adult mice, B-FABP is predominantly expressed in the olfactory bulb. ..
  4. Kuhlbrodt K, Herbarth B, Sock E, Enderich J, Hermans Borgmeyer I, Wegner M. Cooperative function of POU proteins and SOX proteins in glial cells. J Biol Chem. 1998;273:16050-7 pubmed
    ..Our data suggest the existence of a specific code in which POU proteins require specific Sox proteins to exhibit cooperative effects in glial cells. ..
  5. Elsing C, Gorski J, Boeker C, Stremmel W. Long-chain fatty acid uptake by skeletal myocytes: a confocal laser scanning microscopy study. Cell Mol Life Sci. 1998;54:744-50 pubmed
    ..Membrane hyper- and depolarization decreased uptake rates. This study demonstrates for the first time kinetic data from isolated myocytes with evidence for a carrier-mediated transport mechanism for long-chain fatty acids. ..
  6. Bernstein H, Keilhoff G, Seidel B, Stanarius A, Huang P, Fishman M, et al. Expression of hypothalamic peptides in mice lacking neuronal nitric oxide synthase: reduced beta-END immunoreactivity in the arcuate nucleus. Neuroendocrinology. 1998;68:403-11 pubmed
    ..Hence, the reduction of hypothalamic beta-END is probably a posttranslational event that might reflect a disturbed endorphinergic innervation of those hypothalamic neurons which normally express nNOS. ..
  7. Dörflinger U, Pscherer A, Moser M, Rümmele P, Schule R, Buettner R. Activation of somatostatin receptor II expression by transcription factors MIBP1 and SEF-2 in the murine brain. Mol Cell Biol. 1999;19:3736-47 pubmed
    ..In summary, our data for the first time define a regulatory role for the transcription factor MIBP1 in mediating spatially and temporally regulated SSTR-2 expression in the brain. ..
  8. Hol E, Schwaiger F, Werner A, Schmitt A, Raivich G, Kreutzberg G. Regulation of the LIM-type homeobox gene islet-1 during neuronal regeneration. Neuroscience. 1999;88:917-25 pubmed
    ..Moreover, in the adult nervous system islet-1 might be one of the transcription factors regulating the expression of proteins significant for the physiological intact neuronal phenotype. ..
  9. Pabst S, Hazzard J, Antonin W, Sudhof T, Jahn R, Rizo J, et al. Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions. J Biol Chem. 2000;275:19808-18 pubmed
    ..Complexins may regulate the function of ternary complexes and control membrane fusion through this interaction. ..

More Information

Publications201 found, 100 shown here

  1. Lang T, Bruns D, Wenzel D, Riedel D, Holroyd P, Thiele C, et al. SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis. EMBO J. 2001;20:2202-13 pubmed
    ..This suggests that high local concentrations of SNAREs are required for efficient fusion. ..
  2. Hentschke M, Süsens U, Borgmeyer U. Domains of ERRgamma that mediate homodimerization and interaction with factors stimulating DNA binding. Eur J Biochem. 2002;269:4086-97 pubmed
    ..The stimulating activity was further characterized and its target sequence narrowed down to a small element in the hinge region. ..
  3. Schumacher S, Stube E. Regulated binding of the fibrinogen-like domains of tenascin-R and tenascin-C to the neural EGF family member CALEB. J Neurochem. 2003;87:1213-23 pubmed
    ..While both CALEB-80 and CALEB-140 are expressed in the plexiform layers and the optic fiber layer of embryonic chicken retina, CALEB-140 labeling is more intense in the optic fiber layer in comparison to the inner plexiform layer. ..
  4. Bentmann A, Schmidt M, Reuss S, Wolfrum U, Hankeln T, Burmester T. Divergent distribution in vascular and avascular mammalian retinae links neuroglobin to cellular respiration. J Biol Chem. 2005;280:20660-5 pubmed publisher
    ..Our results clearly demonstrate an association of neuroglobin and mitochondria, thus supporting the hypothesis that neuroglobin is a respiratory protein that supplies oxygen to the respiratory chain...
  5. Speidel D, Bruederle C, Enk C, Voets T, Varoqueaux F, Reim K, et al. CAPS1 regulates catecholamine loading of large dense-core vesicles. Neuron. 2005;46:75-88 pubmed
    ..We conclude that CAPS1 is required for an essential step in the uptake or storage of catecholamines in LDCVs. ..
  6. Metzger M, Conrad S, Alvarez Bolado G, Skutella T, Just L. Gene expression of the repulsive guidance molecules during development of the mouse intestine. Dev Dyn. 2005;234:169-75 pubmed
  7. Renner A, Fiebig B, Weber B, Wissinger B, Andreasson S, Gal A, et al. Phenotypic variability and long-term follow-up of patients with known and novel PRPH2/RDS gene mutations. Am J Ophthalmol. 2009;147:518-530.e1 pubmed publisher
    ..FAF and OCT are helpful tools for diagnosis and evaluation of disease progression. We report novel PRPH2 mutations in patients with CACD, CRD, and adRP. ..
  8. Ceyhan G, Demir I, Rauch U, Bergmann F, Müller M, Buchler M, et al. Pancreatic neuropathy results in "neural remodeling" and altered pancreatic innervation in chronic pancreatitis and pancreatic cancer. Am J Gastroenterol. 2009;104:2555-65 pubmed publisher
    ..The aim of this study was to identify the influence of these neuropathic changes on the quality of pancreatic innervation, intrapancreatic glia, and visceral pain...
  9. Pänke O, Weigel W, Schmidt S, Steude A, Robitzki A. A cell-based impedance assay for monitoring transient receptor potential (TRP) ion channel activity. Biosens Bioelectron. 2011;26:2376-82 pubmed publisher
  10. Tran Van H, Avota E, Börtlein C, Mueller N, Schneider Schaulies S. Measles virus modulates dendritic cell/T-cell communication at the level of plexinA1/neuropilin-1 recruitment and activity. Eur J Immunol. 2011;41:151-63 pubmed publisher
    ..To the best of our knowledge, this is the first example of viral targeting of SEMA receptor function in the IS. ..
  11. Oellerich T, Bremes V, Neumann K, Bohnenberger H, Dittmann K, Hsiao H, et al. The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85. EMBO J. 2011;30:3620-34 pubmed publisher
  12. Zhao S, Studer D, Chai X, Graber W, Brose N, Nestel S, et al. Structural plasticity of hippocampal mossy fiber synapses as revealed by high-pressure freezing. J Comp Neurol. 2012;520:2340-51 pubmed publisher
    ..These findings show that activation of hippocampal mossy fibers induces pre- and postsynaptic structural changes at mossy fiber synapses that can be monitored by EM. ..
  13. Schweitzer J, Löhr H, Bonkowsky J, Hübscher K, Driever W. Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development. 2013;140:93-106 pubmed publisher
    ..Therefore, Sim1a and Arnt2 contribute to control of lateral positioning of longitudinal hypothalamic-spinal axons by negative regulation of robo3a.1 expression, which in turn attenuates the repulsive activity of Robo2. ..
  14. Rangrez A, Bernt A, Poyanmehr R, Harazin V, Boomgaarden I, Kuhn C, et al. Dysbindin is a potent inducer of RhoA-SRF-mediated cardiomyocyte hypertrophy. J Cell Biol. 2013;203:643-56 pubmed publisher
    ..Future in vivo studies should examine the significance of Dysbindin in cardiomyopathy. ..
  15. Mayerhofer A, Hemmings H, Snyder G, Greengard P, Boddien S, Berg U, et al. Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro. J Clin Endocrinol Metab. 1999;84:257-64 pubmed
    ..Taken together, the presence of DA and a functional DA receptor and DARPP-32 indicate that a novel, physiological regulatory pathway involving DA exists in the human ovary. ..
  16. Wolfrum C, Ellinghaus P, Fobker M, Seedorf U, Assmann G, Borchers T, et al. Phytanic acid is ligand and transcriptional activator of murine liver fatty acid binding protein. J Lipid Res. 1999;40:708-14 pubmed
    ..2-fold induction of CAT expression. These findings, both in vivo and in vitro, demonstrate that phytanic acid is a transcriptional activator of L-FABP expression and that this effect is mediated via PPARalpha. ..
  17. Schlüter O, Schnell E, Verhage M, Tzonopoulos T, Nicoll R, Janz R, et al. Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release. J Neurosci. 1999;19:5834-46 pubmed
    ..Our data thus demonstrate that rabphilin is endowed with the properties of a rab3 effector but is not essential for the regulatory functions of rab3 in synaptic transmission. ..
  18. Dahmen N, Jungblut P, Fischer V, Schrank M, Reuss S, Rujescu D, et al. Detection of TOAD-64 in adult rat brain as revealed by two-dimensional protein gel electrophoresis followed by MALDI mass spectrometry possible modulatory effect of chronic haloperidol treatment. Prog Neuropsychopharmacol Biol Psychiatry. 2002;26:693-8 pubmed
  19. Abbasi A, Paparidis Z, Malik S, Goode D, Callaway H, Elgar G, et al. Human GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers. PLoS ONE. 2007;2:e366 pubmed
  20. Mitz S, Reuss S, Folkow L, Blix A, Ramirez J, Hankeln T, et al. When the brain goes diving: glial oxidative metabolism may confer hypoxia tolerance to the seal brain. Neuroscience. 2009;163:552-60 pubmed publisher
  21. Noack R, Frede S, Albrecht P, Henke N, Pfeiffer A, Knoll K, et al. Charcot-Marie-Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential. Hum Mol Genet. 2012;21:150-62 pubmed publisher
    ..Thus, our results suggest that the potential GST GDAP1 is implicated in the control of the cellular GHS content and mitochondrial activity, suggesting an involvement of oxidative stress in the pathogenesis of CMT4A. ..
  22. Petric S, Klein S, Dannenberg L, Lahres T, Clasen L, Schmidt K, et al. Pannexin-1 Deficient Mice Have an Increased Susceptibility for Atrial Fibrillation and Show a QT-Prolongation Phenotype. Cell Physiol Biochem. 2016;38:487-501 pubmed publisher
    ..Panx1 seems to play an important role in murine cardiac electrophysiology and warrants further consideration in the context of hereditary forms of atrial fibrillation. ..
  23. Jurincic Winkler C, Metz K, Klippel K. Melanotic neuroectodermal tumor of infancy (MNTI) in the epididymis. A case report with immunohistological studies and special consideration of malignant features. Zentralbl Pathol. 1994;140:181-5 pubmed
    ..The small tumor cells were only slightly positive for GFAP, NKI-C3, NSE, and S100 but they were negative for cytokeratin and vimentin. Neurofilament and chromogranin could not be proved in the tumor...
  24. Ashery Padan R, Alvarez Bolado G, Klamt B, Gessler M, Gruss P. Fjx1, the murine homologue of the Drosophila four-jointed gene, codes for a putative secreted protein expressed in restricted domains of the developing and adult brain. Mech Dev. 1999;80:213-7 pubmed
    ..In the embryo, strong expression can further be seen in the apical ectodermal ridge of fore- and hindlimbs and in the ectoderm of the branchial arches. ..
  25. Brakebusch C, Seidenbecher C, Asztely F, Rauch U, Matthies H, Meyer H, et al. Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory. Mol Cell Biol. 2002;22:7417-27 pubmed
    ..Detailed behavioral analysis revealed no statistically significant deficits in learning and memory. These data indicate that brevican is not crucial for brain development but has restricted structural and functional roles. ..
  26. Zanner R, Gratzl M, Prinz C. Expression of the endocytic proteins dynamin and amphiphysin in rat gastric enterochromaffin-like cells. J Cell Sci. 2004;117:2369-76 pubmed
    ..To our knowledge, this is the first demonstration of the co-expression of all three dynamin isoforms in a non-tumor cell. ..
  27. Paukert M, Babini E, Pusch M, Grunder S. Identification of the Ca2+ blocking site of acid-sensing ion channel (ASIC) 1: implications for channel gating. J Gen Physiol. 2004;124:383-94 pubmed
    ..These results show that channel block by Ca2+ and H+ gating are not intrinsically linked. ..
  28. Bock N, Moll G, Wicker M, Pilz J, Ruther E, Banaschewski T, et al. Early administration of tiapride to young rats without long-lasting changes in the development of the dopaminergic system. Pharmacopsychiatry. 2004;37:163-7 pubmed
    ..These data suggest that tiapride treatment during postnatal brain development causes no long-lasting changes in the development of the central dopaminergic system and is in line with clinical experience in children. ..
  29. Iandiev I, Pannicke T, Reichel M, Wiedemann P, Reichenbach A, Bringmann A. Expression of aquaporin-1 immunoreactivity by photoreceptor cells in the mouse retina. Neurosci Lett. 2005;388:96-9 pubmed
    ..The data suggest that photoreceptor cells, but not Müller cells, express aquaporin-1 in the murine retina. ..
  30. Dimova K, Kalkhof S, Pottratz I, Ihling C, Rodriguez Castaneda F, Liepold T, et al. Structural insights into the calmodulin-Munc13 interaction obtained by cross-linking and mass spectrometry. Biochemistry. 2009;48:5908-21 pubmed publisher
  31. Holzschuh J, Barrallo Gimeno A, Ettl A, Durr K, Knapik E, Driever W. Noradrenergic neurons in the zebrafish hindbrain are induced by retinoic acid and require tfap2a for expression of the neurotransmitter phenotype. Development. 2003;130:5741-54 pubmed
    ..Thus, although the inductive signals may be distinct, hindbrain NA neurons of the locus coeruleus and the posterior groups both require Tfap2a to establish their noradrenergic identity. ..
  32. Hauck S, Kinkl N, Deeg C, Swiatek De Lange M, Schöffmann S, Ueffing M. GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells. Mol Cell Biol. 2006;26:2746-57 pubmed
    ..We provide here a detailed model of GDNF-induced signaling in mammalian retina and propose that the GDNF-induced rescue effect on mutated photoreceptors is an indirect effect mediated by retinal Mueller glial cells. ..
  33. Inhoff T, Stengel A, Peter L, Goebel M, TACHE Y, Bannert N, et al. Novel insight in distribution of nesfatin-1 and phospho-mTOR in the arcuate nucleus of the hypothalamus of rats. Peptides. 2010;31:257-62 pubmed publisher
  34. Ringer C, Weihe E, Schütz B. SOD1G93A Mutant Mice Develop a Neuroinflammation-Independent Dendropathy in Excitatory Neuronal Subsets of the Olfactory Bulb and Retina. J Neuropathol Exp Neurol. 2017;76:769-778 pubmed publisher
    ..Thus, we identified a new pathology hallmark in SOD1G93A ALS mice: a glutamatergic sensory neuron dendropathy restricted to olfactory bulb mitral cells and retinal ganglionic cells. ..
  35. You L, Ebner S, Kruse F. Glial cell-derived neurotrophic factor (GDNF)-induced migration and signal transduction in corneal epithelial cells. Invest Ophthalmol Vis Sci. 2001;42:2496-504 pubmed
    ..FAK seems to be an upstream regulator of the MAPK cascade for GDNF signal transduction. As an inducer of FAK-dependent corneal epithelial migration, GDNF may play an important role in corneal regeneration and wound healing. ..
  36. Lang U, Bajbouj M, Wernicke C, Rommelspacher H, Danker Hopfe H, Gallinat J. No association of a functional polymorphism in the serotonin transporter gene promoter and anxiety-related personality traits. Neuropsychobiology. 2004;49:182-4 pubmed
    ..f. = 2) in all subjects. Given the small effect of this 5-HTT polymorphism on behaviour in previous studies, a lack of significant genotype differences in these tests could be due to considerable individual variability in these measures. ..
  37. Kuan Y, Gruebl T, Soba P, Eggert S, Nesic I, Back S, et al. PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2. J Biol Chem. 2006;281:40114-23 pubmed
    ..Finally, we show that PAT1a promotes APP/APLPs processing, resulting in increased secretion of beta-amyloid peptide. Taken together, our data establish PAT1a as a functional link between APP/APLPs transport and their processing. ..
  38. Vogel T, Ahrens S, Büttner N, Krieglstein K. Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component. Cereb Cortex. 2010;20:661-71 pubmed publisher
  39. Horvath B, Niedermeier A, Podstawa E, Muller R, Hunzelmann N, Karpati S, et al. IgA autoantibodies in the pemphigoids and linear IgA bullous dermatosis. Exp Dermatol. 2010;19:648-53 pubmed publisher
    ..IgA against the COOH- and NH(2)-terminus of BP230, respectively, was detected in 6/30 of the BP, 1/10 of the MMP, 1/6 of the LABD and 0/8 control sera. IgA reactivity against BP180 and/or BP230 is a common finding in the pemphigoids. ..
  40. Buss A, Pech K, Kakulas B, Martin D, Schoenen J, Noth J, et al. NG2 and phosphacan are present in the astroglial scar after human traumatic spinal cord injury. BMC Neurol. 2009;9:32 pubmed publisher
    ..The present data points to the importance of such correlative investigations for demonstrating the clinical relevance of experimental data. ..
  41. Cevikbas F, Wang X, Akiyama T, Kempkes C, Savinko T, Antal A, et al. A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1. J Allergy Clin Immunol. 2014;133:448-60 pubmed publisher
    ..Thus targeting neuronal IL-31RA might be effective in the management of TH2-mediated itch, including atopic dermatitis and cutaneous T-cell lymphoma. ..
  42. Hiesinger P, Reiter C, Schau H, Fischbach K. Neuropil pattern formation and regulation of cell adhesion molecules in Drosophila optic lobe development depend on synaptobrevin. J Neurosci. 1999;19:7548-56 pubmed
    ..A possible causal link to fine-tuning processes that may include synaptic plasticity in the development of the Drosophila CNS is discussed. ..
  43. Humrich J, Bermel C, Bünemann M, Härmark L, Frost R, Quitterer U, et al. Phosducin-like protein regulates G-protein betagamma folding by interaction with tailless complex polypeptide-1alpha: dephosphorylation or splicing of PhLP turns the switch toward regulation of Gbetagamma folding. J Biol Chem. 2005;280:20042-50 pubmed
    ..We therefore conclude that the strong inhibitory action of PhLP(S) on Gbetagamma signaling is the result of a previously unrecognized mechanism of Gbetagamma-regulation, inhibition of Gbetagamma-folding by interference with TCP-1alpha. ..
  44. Huang B, Schiefer J, Sass C, Landwehrmeyer G, Kosinski C, Kochanek S. High-capacity adenoviral vector-mediated reduction of huntingtin aggregate load in vitro and in vivo. Hum Gene Ther. 2007;18:303-11 pubmed
    ..In both models an efficient reduction in mutant Htt aggregate load measured by decreased Htt-IR aggregate formation was observed. Our results support the further development of shRNA for HD therapy. ..
  45. Specht B, Bartetzko N, Hohoff C, Kuhl H, Franke R, Borchers T, et al. Mammary derived growth inhibitor is not a distinct protein but a mix of heart-type and adipocyte-type fatty acid-binding protein. J Biol Chem. 1996;271:19943-9 pubmed
    ..Taking into account that deviations of the MDGI sequence from the bovine H-FABP sequence correspond with A-FABP we attribute the structure originally reported as MDGI to a mix of these proteins. ..
  46. Kretz O, Fester L, Wehrenberg U, Zhou L, Brauckmann S, Zhao S, et al. Hippocampal synapses depend on hippocampal estrogen synthesis. J Neurosci. 2004;24:5913-21 pubmed
    ..However, synaptophysin expression was upregulated under these conditions. Our results point to an essential role of endogenous hippocampal estrogen synthesis in the maintenance of hippocampal spine synapses. ..
  47. Goebbels S, Bormuth I, Bode U, Hermanson O, Schwab M, Nave K. Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. Genesis. 2006;44:611-21 pubmed
    ..The NEX-Cre mouse will be a valuable tool for behavioral research and the conditional inactivation of target genes in pyramidal neurons of the dorsal telencephalon. ..
  48. Kowalski J, Geuting M, Paul S, Dieni S, Laurens J, Zhao S, et al. Proper layering is important for precisely timed activation of hippocampal mossy cells. Cereb Cortex. 2010;20:2043-54 pubmed publisher
    ..Thus, disturbed lamination results in aberrant synaptic connectivity and altered timing of action potential generation. These results highlight the importance of a layered cortical structure for information processing. ..
  49. Hezel M, Ebrahimi F, Koch M, Dehghani F. Propidium iodide staining: a new application in fluorescence microscopy for analysis of cytoarchitecture in adult and developing rodent brain. Micron. 2012;43:1031-8 pubmed publisher
    ..Taken together, post-fixation PI staining provides a detailed insight in the morphology of both developing and adult brain tissues in fluorescence microscopy. ..
  50. M ller Schmid A, Rinder H, Lottspeich F, Gertzen E, Hoffmann W. Ependymins from the cerebrospinal fluid of salmonid fish: gene structure and molecular characterization. Gene. 1992;118:189-96 pubmed
    ..The structure of one Epd gene and its flanking regions have been determined for the Atlantic salmon (Salmo salar). Six exons were deduced by comparison with the corresponding cDNA sequence from O. mykiss (almost 98% homology with Om-II)...
  51. Botchkarev V, Eichmuller S, Johansson O, Paus R. Hair cycle-dependent plasticity of skin and hair follicle innervation in normal murine skin. J Comp Neurol. 1997;386:379-95 pubmed
  52. Rossoll W, Kröning A, Ohndorf U, Steegborn C, Jablonka S, Sendtner M. Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?. Hum Mol Genet. 2002;11:93-105 pubmed
    ..Interestingly, hnRNP-R is predominantly located in axons of motor neurons and co-localizes with Smn in this cellular compartment. Thus, this finding could provide a key to understand a motor neuron-specific Smn function in SMA. ..
  53. Gebhardt C, Del Turco D, Drakew A, Tielsch A, Herz J, Frotscher M, et al. Abnormal positioning of granule cells alters afferent fiber distribution in the mouse fascia dentata: morphologic evidence from reeler, apolipoprotein E receptor 2-, and very low density lipoprotein receptor knockout mice. J Comp Neurol. 2002;445:278-92 pubmed
    ..These data provide further evidence for a role of granule cells in the laminar termination of commissural/associational afferents to the fascia dentata. ..
  54. Nagy G, Kim J, Pang Z, Matti U, Rettig J, Sudhof T, et al. Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation. J Neurosci. 2006;26:632-43 pubmed
    ..We conclude that exocytosis from mouse chromaffin cells can be modified by the differential expression of Syt isoforms and by Syt abundance but not by phosphorylation of Syt1. ..
  55. Courtial N, Smink J, Kuvardina O, Leutz A, Gothert J, Lausen J. Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP. FASEB J. 2012;26:523-32 pubmed publisher
    ..1 and MITF. The identification of Tal1 as a factor involved in cell fusion contributes to the understanding of osteoclast-associated diseases, including osteoporosis. ..
  56. Morris Rosendahl D, Burgert E, Uyanik G, Mayerova A, Duval F, Macher J, et al. Analysis of the CAG repeats in the SCA1 and B37 genes in schizophrenic and bipolar I disorder patients: tentative association between B37 and schizophrenia. Am J Med Genet. 1997;74:324-30 pubmed
    ..This result possibly indicates linkage disequilibrium with another locus on chromosome 12p and therefore deserves further attention. No association was found between the B37 CAG repeat and patients with BPD. ..
  57. Schönberger J, Ruschoff J, Grimm D, Marienhagen J, Rümmele P, Meyringer R, et al. Glucose transporter 1 gene expression is related to thyroid neoplasms with an unfavorable prognosis: an immunohistochemical study. Thyroid. 2002;12:747-54 pubmed
    ..Therefore, determination of GLUT1 expression in thyroid cancer tissue may be a prognostic marker, and FDG-PET may be a helpful technique in identifying patients at a higher risk. ..
  58. Wöhrle S, Wallmen B, Hecht A. Differential control of Wnt target genes involves epigenetic mechanisms and selective promoter occupancy by T-cell factors. Mol Cell Biol. 2007;27:8164-77 pubmed
    ..These involve epigenetic modifications of promoter chromatin and differential promoter occupancy by functionally distinct TCF proteins, which together determine susceptibility to Wnt signaling. ..
  59. Sakthivelu V, Seidel R, Winklhofer K, Tatzelt J. Conserved stress-protective activity between prion protein and Shadoo. J Biol Chem. 2011;286:8901-8 pubmed publisher
    ..Our study reveals a conserved physiological activity between PrP(C) and Sho to protect cells from stress-induced toxicity and suggests that Sho and PrP(C) might act on similar signaling pathways. ..
  60. Rosenthal E, Tonchev A, Stoykova A, Chowdhury K. Regulation of archicortical arealization by the transcription factor Zbtb20. Hippocampus. 2012;22:2144-56 pubmed publisher
    ..Our data also suggest that the signaling factor Wnt3a is a putative molecular partner of TF Zbtb20 in this patterning process. ..
  61. Homberg U, Hoskins S, Hildebrand J. Distribution of acetylcholinesterase activity in the deutocerebrum of the sphinx moth Manduca sexta. Cell Tissue Res. 1995;279:249-59 pubmed
    ..The study provides further evidence for cholinergic neurotransmission of most antennal afferents. The AChE-containing interneurons might be cholinergic as well or use the enzyme for functions unrelated to hydrolysis of acetylcholine. ..
  62. Varoqueaux F, Sons M, Plomp J, Brose N. Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse. Mol Cell Biol. 2005;25:5973-84 pubmed
    ..Thus, non-Munc13 priming proteins exist at this synapse or vesicle priming occurs in part spontaneously: i.e., without dedicated priming proteins in the release machinery. ..
  63. Lüke Y, Zaim H, Karakesisoglou I, Jaeger V, Sellin L, Lu W, et al. Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. J Cell Sci. 2008;121:1887-98 pubmed publisher
  64. Rueger M, Muesken S, Walberer M, Jantzen S, Schnakenburg K, Backes H, et al. Effects of minocycline on endogenous neural stem cells after experimental stroke. Neuroscience. 2012;215:174-83 pubmed publisher
    ..We found minocycline, previously implied in attenuating microglial activation, to have positive effects on endogenous NSC survival. These findings hold promise for the development of novel treatments in stroke therapy. ..
  65. Miragall F, Albiez P, Bartels H, de Vries U, Dermietzel R. Expression of the gap junction protein connexin43 in the subependymal layer and the rostral migratory stream of the mouse: evidence for an inverse correlation between intensity of connexin43 expression and cell proliferation activity. Cell Tissue Res. 1997;287:243-53 pubmed
    ..A marked reverse correlation of both parameters was also observed in primary cell cultures from olfactory bulbs at day 6 after seeding. ..
  66. Bangsow T, Schepelmann S, Martin C, May M, Oberthür A, Perl S, et al. Identification of a gene selectively expressed in the brain, which encodes a putative transmembrane protein and a soluble cytoplasmic isoform. Eur J Biochem. 1998;256:24-35 pubmed
    ..However, our findings suggest that they may be generated by alternative promoter usage, leading to the expression of a membrane protein and its truncated cytoplasmic isoform. ..
  67. Kühn K, Wellen J, Link N, Maskri L, Lübbert H, Stichel C. The mouse MPTP model: gene expression changes in dopaminergic neurons. Eur J Neurosci. 2003;17:1-12 pubmed
    ..All genes investigated were affected. However, alpha-synuclein was the only gene that was exclusively up-regulated in MPTP-treated animals displaying cell death. ..
  68. Burk K, Zuhlke C, Konig I, Ziegler A, Schwinger E, Globas C, et al. Spinocerebellar ataxia type 5: clinical and molecular genetic features of a German kindred. Neurology. 2004;62:327-9 pubmed
    ..Imaging studies demonstrated cortical cerebellar atrophy. Progression is slow even in patients with a disease onset during the second decade. The age at onset varies from 15 to 50 years. ..
  69. Mellies U, Dohna Schwake C, Stehling F, Voit T. Sleep disordered breathing in spinal muscular atrophy. Neuromuscul Disord. 2004;14:797-803 pubmed
    ..05 for all). In children with spinal muscular atrophy sleep disordered breathing may cause relevant impairment of sleep and well-being. Both can be highly improved by nocturnal non-invasive ventilation. ..
  70. Feliciani C, Caldarola G, Kneisel A, Podstawa E, Pfütze M, Pfutzner W, et al. IgG autoantibody reactivity against bullous pemphigoid (BP) 180 and BP230 in elderly patients with pruritic dermatoses. Br J Dermatol. 2009;161:306-12 pubmed publisher
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