Experts and Doctors on muscle spindles in United States


Locale: United States
Topic: muscle spindles

Top Publications

  1. Lin C, Crago P. Structural model of the muscle spindle. Ann Biomed Eng. 2002;30:68-83 pubmed
    ..The current model provides a powerful tool for simulation studies of neuromusculoskeletal systems, and demonstrates the feasibility of using a structural approach to model complex neurophysiological systems. ..
  2. Pickar J. An in vivo preparation for investigating neural responses to controlled loading of a lumbar vertebra in the anesthetized cat. J Neurosci Methods. 1999;89:87-96 pubmed
  3. Stelzer J, Larsson L, Fitzsimons D, Moss R. Activation dependence of stretch activation in mouse skinned myocardium: implications for ventricular function. J Gen Physiol. 2006;127:95-107 pubmed
    ..Such a mechanism would contribute to increased systolic ejection in response to increased delivery of activator Ca2+ during excitation-contraction coupling. ..
  4. Hornberger T. Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle. Int J Biochem Cell Biol. 2011;43:1267-76 pubmed publisher
  5. Lin C, Crago P. Neural and mechanical contributions to the stretch reflex: a model synthesis. Ann Biomed Eng. 2002;30:54-67 pubmed
    ..The model did not accurately predict the responses at higher stretch velocities, due to failure of the extrafusal muscle model. ..
  6. Taylor M, Vancura R, Patterson C, Williams J, Riekhof J, Wright D. Postnatal regulation of limb proprioception by muscle-derived neurotrophin-3. J Comp Neurol. 2001;432:244-58 pubmed
    ..However, our results also show that NT-3 may be therapeutic for proprioceptive axons immediately after nerve injury by delaying axon degeneration. ..
  7. Wright D, Williams J, McDonald J, Carlsten J, Taylor M. Muscle-derived neurotrophin-3 reduces injury-induced proprioceptive degeneration in neonatal mice. J Neurobiol. 2002;50:198-208 pubmed
    ..Our results demonstrate that in addition to its early actions on sensory neuron generation and naturally occurring cell death, NT-3 has important neuroprotective effects on muscle afferents during postnatal development. ..
  8. Fowler S, Zarcone T, Chen R, Taylor M, Wright D. Low grip strength, impaired tongue force and hyperactivity induced by overexpression of neurotrophin-3 in mouse skeletal muscle. Int J Dev Neurosci. 2002;20:303-8 pubmed
  9. Taylor M, Holdeman A, Weltmer S, Ryals J, Wright D. Modulation of muscle spindle innervation by neurotrophin-3 following nerve injury. Exp Neurol. 2005;191:211-22 pubmed
    ..Finally, exposure of muscle afferent fibers to NT-3 prior to injury alters axonal responses both in vitro and in vivo. ..

More Information


  1. Muller K, Ryals J, Feldman E, Wright D. Abnormal muscle spindle innervation and large-fiber neuropathy in diabetic mice. Diabetes. 2008;57:1693-701 pubmed publisher
    ..In addition, these studies provide a novel method to assay therapeutic interventions designed for diabetes-induced large-fiber dysfunction. ..