Experts and Doctors on mullerian ducts in Germany

Summary

Locale: Germany
Topic: mullerian ducts

Top Publications

  1. Leffler A, Ludwig M, Schmitt O, Busch L. Germ cell migration and early development of the gonads in the trisomy 16 mouse--an animal model for Down's syndrome. Ann Anat. 1999;181:247-52 pubmed
  2. Marten K, Vosshenrich R, Funke M, Obenauer S, Baum F, Grabbe E. MRI in the evaluation of müllerian duct anomalies. Clin Imaging. 2003;27:346-50 pubmed
    ..MRI is a valuable tool in diagnosis of MDA subtypes. Its use will help to spare patients mutilating surgery and to prevent pregnancy-associated complications. ..
  3. Kenngott R, Sinowatz F. Expression and distribution of intermediate-filament proteins and laminin during the development of the bovine Müllerian duct. Anat Histol Embryol. 2008;37:223-30 pubmed publisher
    ..We conclude from our immunohistochemical results that the epithelial cells of the Wollfian duct do not contribute cells to the developing Müllerian duct. ..
  4. Barrionuevo F, Bagheri Fam S, Klattig J, Kist R, Taketo M, Englert C, et al. Homozygous inactivation of Sox9 causes complete XY sex reversal in mice. Biol Reprod. 2006;74:195-201 pubmed
    ..Our results provide in vivo proof that, in contrast to the situation in humans, complete XY sex reversal in mice requires inactivation of both Sox9 alleles and that Sox9 is essential for testogenesis in mice. ..
  5. Oppelt P, Renner S, Kellermann A, Brucker S, Hauser G, Ludwig K, et al. Clinical aspects of Mayer-Rokitansky-Kuester-Hauser syndrome: recommendations for clinical diagnosis and staging. Hum Reprod. 2006;21:792-7 pubmed
    ..This retrospective study examined the issue of associated malformations, subtyping, and the frequency distribution of subtypes in MRKH syndrome...
  6. Bogdanova N, Siebers U, Kelsch R, Markoff A, Röpke A, Exeler R, et al. Blood chimerism in a girl with Down syndrome and possible freemartin effect leading to aplasia of the Müllerian derivatives. Hum Reprod. 2010;25:1339-43 pubmed publisher
    ..This disorder of sex development is known as freemartin phenomenon in female cattle from sex-discordant twin pairs...
  7. Ledig S, Schippert C, Strick R, Beckmann M, Oppelt P, Wieacker P. Recurrent aberrations identified by array-CGH in patients with Mayer-Rokitansky-Küster-Hauser syndrome. Fertil Steril. 2011;95:1589-94 pubmed publisher
    ..To identify genetic causes of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome...
  8. Rall K, Barresi G, Walter M, Poths S, Haebig K, Schaeferhoff K, et al. A combination of transcriptome and methylation analyses reveals embryologically-relevant candidate genes in MRKH patients. Orphanet J Rare Dis. 2011;6:32 pubmed publisher
    ..Thus, our data stimulate new research directions to decipher the pathogenic basis of MRKH syndrome. ..
  9. Ledig S, Brucker S, Barresi G, Schömburg J, Rall K, Wieacker P. Frame shift mutation of LHX1 is associated with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. Hum Reprod. 2012;27:2872-5 pubmed publisher
    ..The LHX1 gene, which is located in the deletion interval, has been suggested to be a strong candidate, because targeting inactivation of Lhx1 causes a complex phenotype including aplasia of the Müllerian ducts...

More Information

Publications10

  1. Ekici A, Strissel P, Oppelt P, Renner S, Brucker S, Beckmann M, et al. HOXA10 and HOXA13 sequence variations in human female genital malformations including congenital absence of the uterus and vagina. Gene. 2013;518:267-72 pubmed publisher
    ..Rare DNA sequence variations in the HOXA10 gene could contribute to the misdevelopment of female internal genitalia...