Experts and Doctors on molecular sequence data in Japan


Locale: Japan
Topic: molecular sequence data

Top Publications

  1. Miyazaki Y, Setoguchi M, Yoshida S, Higuchi Y, Akizuki S, Yamamoto S. The mouse osteopontin gene. Expression in monocytic lineages and complete nucleotide sequence. J Biol Chem. 1990;265:14432-8 pubmed
    ..The 5' end of the murine OP gene was defined by primer extension and S1 nuclease mapping. Sequence analysis of the 5'-flanking DNA revealed the presence of many potential regulatory motifs. ..
  2. Mukai H, Kuno T, Tanaka H, Hirata D, Miyakawa T, Tanaka C. Isolation and characterization of SSE1 and SSE2, new members of the yeast HSP70 multigene family. Gene. 1993;132:57-66 pubmed
    ..Disruption of SSE1 results in slow-growing cells at any temperature. No phenotypic effects of the mutation in SSE2 were detected, and the growth property of the sse1sse2 double mutant was the same as that of the sse1 single mutant. ..
  3. Tanaka R, Yoshida K, Nakayashiki T, Masuda T, Tsuji H, Inokuchi H, et al. Differential expression of two hemA mRNAs encoding glutamyl-tRNA reductase proteins in greening cucumber seedlings. Plant Physiol. 1996;110:1223-30 pubmed
  4. Yokote R, Sato M, Matsubara S, Ohye H, Niimi M, Murao K, et al. Molecular cloning and gene expression of growth hormone-releasing peptide receptor in rat tissues. Peptides. 1998;19:15-20 pubmed
    ..Microdissection revealed that GHRP receptor mRNAs were localized predominantly in the arcuate nucleus and ventromedial hypothalamus. ..
  5. Takechi K, Sakamoto W, Utsugi S, Murata M, Motoyoshi F. Characterization of a flower-specific gene encoding a putative myrosinase binding protein in Arabidopsis thaliana. Plant Cell Physiol. 1999;40:1287-96 pubmed
  6. Nasuno E, Kimura N, Fujita M, Nakatsu C, Kamagata Y, Hanada S. Phylogenetically novel LuxI/LuxR-type quorum sensing systems isolated using a metagenomic approach. Appl Environ Microbiol. 2012;78:8067-74 pubmed publisher
    ..We demonstrated that metagenomic screening is useful to provide further insight into the phylogenetic diversity of bacterial QS systems by describing two new LuxI/LuxR-type QS systems from uncultured bacteria. ..
  7. Kimura H, Hitomi M, Odani S, Koide T, Arakawa M, Ono T. Rat heart fatty acid-binding protein. Evidence that supports the amino acid sequence predicted from the cDNA. Biochem J. 1989;260:303-6 pubmed
    ..Our result completely agreed with the amino acid sequence predicted from the cDNA analyses, providing evidence for the actual existence of the molecular species predicted from the cDNA. ..
  8. Maeda H, Hashimoto R, Ogura T, Hiraga S, Uzawa H. Molecular cloning of a human apoC-III variant: Thr 74----Ala 74 mutation prevents O-glycosylation. J Lipid Res. 1987;28:1405-9 pubmed
    ..As a result of this amino acid replacement, the mutant apoC-III polypeptide is not glycosylated. The mutation in the apoC-III gene creates a novel AluI site that permits diagnosis of the change by Southern blotting of genomic DNA. ..
  9. Kobayashi T, Ikeda K, Ichikawa T, Abe S, Togashi S, Kumanishi T. Molecular cloning of a mouse G-protein-activated K+ channel (mGIRK1) and distinct distributions of three GIRK (GIRK1, 2 and 3) mRNAs in mouse brain. Biochem Biophys Res Commun. 1995;208:1166-73 pubmed

More Information

Publications669 found, 100 shown here

  1. Miyake K, Yamashita Y, Ogata M, Sudo T, Kimoto M. RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. J Immunol. 1995;154:3333-40 pubmed
    ..These results demonstrate that RP105 is a novel member of the leucine-rich repeat protein family, and the first member that is specifically expressed on B cells. ..
  2. Hayasaka K, Nanao K, Takada G, Okamura Ikeda K, Motokawa Y. Isolation and sequence determination of cDNA encoding human T-protein of the glycine cleavage system. Biochem Biophys Res Commun. 1993;192:766-71 pubmed
    ..RNA blot analysis of human liver transcripts and Southern blot analysis of human genomic DNA confirm that human T-protein is encoded by a single gene. ..
  3. Takizawa N, Kaida N, Torigoe S, Moritani T, Sawada T, Satoh S, et al. Identification and characterization of genes encoding polycyclic aromatic hydrocarbon dioxygenase and polycyclic aromatic hydrocarbon dihydrodiol dehydrogenase in Pseudomonas putida OUS82. J Bacteriol. 1994;176:2444-9 pubmed
  4. Yamada T, Kim J, Muramatsu Y, Serikawa T, Matsumoto K. Chromosomal assignments of the genes for the calcineurin A alpha (Calna1) and A beta subunits (Calna2) in the rat. Cytogenet Cell Genet. 1994;67:55-7 pubmed
    ..Both genes, Calna1 and Calna2, were assigned to rat chromosome 15. ..
  5. Kato K, Goto S, Inaguma Y, Hasegawa K, Morishita R, Asano T. Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin. J Biol Chem. 1994;269:15302-9 pubmed
    ..These results suggest that p20 is related to stress proteins. ..
  6. Araki H, Leem S, Phongdara A, Sugino A. Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. Proc Natl Acad Sci U S A. 1995;92:11791-5 pubmed
    ..These results strongly suggest that Dpb11 is a part of the DNA polymerase II complex during chromosomal DNA replication and also acts in a checkpoint pathway during the S phase of the cell cycle to sense stalled DNA replication. ..
  7. Tsuda S, Rieke S, Hashimoto Y, Nakauchi H, Takahama Y. Il-7 supports D-J but not V-DJ rearrangement of TCR-beta gene in fetal liver progenitor cells. J Immunol. 1996;156:3233-42 pubmed
  8. Tsuzuki T, Fujii Y, Sakumi K, Tominaga Y, Nakao K, Sekiguchi M, et al. Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc Natl Acad Sci U S A. 1996;93:6236-40 pubmed
    ..The homozygous Rad51 null mutation can be categorized in cell-autonomous defects. Pre-implantational lethal mutations that disrupt basic molecular functions will thus interfere with cell viability. ..
  9. Arinami T, Takekoshi K, Itokawa M, Hamaguchi H, Toru M. Failure to find associations of the CA repeat polymorphism in the first intron and the Gly-63/Glu-63 polymorphism of the neurotrophin-3 gene with schizophrenia. Psychiatr Genet. 1996;6:13-5 pubmed
    ..We found similar allele and genotype frequencies of both polymorphisms between the schizophrenic and control groups. We failed to support associations between the polymorphisms of the neurotrophin-3 gene analyzed and schizophrenia. ..
  10. Akasaka T, Miura I, Takahashi N, Akasaka H, Yonetani N, Ohno H, et al. A recurring translocation, t(3;6)(q27;p21), in non-Hodgkin's lymphoma results in replacement of the 5' regulatory region of BCL6 with a novel H4 histone gene. Cancer Res. 1997;57:7-12 pubmed
    ..Because H4 gene expression is tightly coupled to DNA replication, this study suggested an immediate mechanism for deregulated expression of BCL6, leading to the development of non-Hodgkin's lymphoma. ..
  11. Amano T, Noro N, Kawabata H, Kobayashi Y, Yoshizato K. Metamorphosis-associated and region-specific expression of calbindin gene in the posterior intestinal epithelium of Xenopus laevis larva. Dev Growth Differ. 1998;40:177-88 pubmed
    ..Considering these results, the origin of adult intestinal epithelial cells was discussed. ..
  12. Okumura Y, Yano M, Murakami M, Mori S, Towatari T, Kido H. The extracellular processing of HIV-1 envelope glycoprotein gp160 by human plasmin. FEBS Lett. 1999;442:39-42 pubmed
    ..Plasmin cleaves gp160 precisely at the C-terminal arginine residue of gp120, and the processing is effectively inhibited by an analogue peptide of the cleavage motif (RXK/RR) and by plasmin inhibitors. ..
  13. Maeda A, Ohguro H, Maeda T, Wada I, Sato N, Kuroki Y, et al. Aberrant expression of photoreceptor-specific calcium-binding protein (recoverin) in cancer cell lines. Cancer Res. 2000;60:1914-20 pubmed
  14. Numata O, Gonda K, Watanabe A, Kurasawa Y. Cytokinesis in Tetrahymena: determination of division plane and organization of contractile ring. Microsc Res Tech. 2000;49:127-35 pubmed
  15. Arimoto Kobayashi S, Anma N, Yoshinaga Y, Douki T, Cadet J, Hayatsu H. Oxidative damage and induced mutations in m13mp2 phage DNA exposed to N-nitrosopyrrolidine with UVA radiation. Mutagenesis. 2000;15:473-7 pubmed
    ..With these hosts, different hot spots were observed and a new GC-->TA hot spot was produced. The formation of 8-oxodGuo in DNA, which is known to induce GC-->TA transversion, may contribute to mutagenesis by NPYR plus UVA. ..
  16. Arimura T, Nakamura T, Hiroi S, Satoh M, Takahashi M, Ohbuchi N, et al. Characterization of the human nebulette gene: a polymorphism in an actin-binding motif is associated with nonfamilial idiopathic dilated cardiomyopathy. Hum Genet. 2000;107:440-51 pubmed
    ..92-20.29), while this association was not found in familial IDC patients (n=24). These observations suggest that the nebulette polymorphism in the actin-binding motif was a novel genetic marker of susceptibility to nonfamilial IDC. ..
  17. Inagaki K, Inagaki J, Dumoulin A, Padovan J, Chait B, Popowicz A, et al. Expression and properties of recombinant HbA2 (alpha2delta2) and hybrids containing delta-beta sequences. J Protein Chem. 2000;19:649-62 pubmed
    ..Molecular modeling studies which attempt to understand these properties of HbA2 are described. ..
  18. Taniguchi Y, Itoh T, Yamada T, Sasaki Y. Genomic structure and promoter analysis of the bovine leptin gene. IUBMB Life. 2002;53:131-5 pubmed
  19. Yamada O, Sakamoto K, Tominaga M, Nakayama T, Koseki T, Fujita A, et al. Cloning and heterologous expression of the antibiotic peptide (ABP) genes from Rhizopus oligosporus NBRC 8631. Biosci Biotechnol Biochem. 2005;69:477-82 pubmed
    ..This result indicates that mature ABP formed the active structure without the aid of other factors from R. oligosporus, and was secreted. ..
  20. Yokoi K, Kawahigashi N, Uchida M, Sugahara K, Shinohara M, Kawasaki K, et al. The two-component cell lysis genes holWMY and lysWMY of the Staphylococcus warneri M phage varphiWMY: cloning, sequencing, expression, and mutational analysis in Escherichia coli. Gene. 2005;351:97-108 pubmed
    ..Upon mitomycin C exposure of S. warneri M, a prophage (phiWMY) was induced and the virion was examined under electron microscopy. PCR amplification and sequencing revealed the presence of the holWMY-lysWMY genes in the phage genome. ..
  21. Nakano K, Bunai F, Numata O. Stg 1 is a novel SM22/transgelin-like actin-modulating protein in fission yeast. FEBS Lett. 2005;579:6311-6 pubmed
  22. Du D, Kato T, Suzuki F, Park E. Binding affinity of full-length and extracellular domains of recombinant human (pro)renin receptor to human renin when expressed in the fat body and hemolymph of silkworm larvae. J Biosci Bioeng. 2009;108:304-9 pubmed publisher
    ..To our knowledge, these are the first findings describing the interaction of transmembrane and extracellular domains of hPRR with ligand and this may help towards the understanding of binding affinity of hPRR to ligand. ..
  23. Matuoka K, Shibata M, Yamakawa A, Takenawa T. Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries. Proc Natl Acad Sci U S A. 1992;89:9015-9 pubmed
  24. Ikeda K, Nagasawa M, Mori H, Araki K, Sakimura K, Watanabe M, et al. Cloning and expression of the epsilon 4 subunit of the NMDA receptor channel. FEBS Lett. 1992;313:34-8 pubmed
    ..The epsilon 4 subunit is thus distinct in functional properties from the epsilon 1, epsilon 2 and epsilon 3 subunits, and contributes further diversity of the NMDA receptor channel. ..
  25. Oka T, Endo Y, Ito M, Miyamoto K, Sasakawa T, Suzuki I, et al. Molecular cloning of chick liver HMG 2a cDNA and developmental expression of HMG 2a mRNA. Biochim Biophys Acta. 1992;1130:224-6 pubmed
    ..2.0 kb and 1.2 kb mRNAs were found in newly hatched chick liver and decreased during postnatal development of chicks. ..
  26. Matsushima M, Takahashi T, Ichinose M, Miki K, Kurokawa K, Takahashi K. Structural and immunological evidence for the identity of prolyl aminopeptidase with leucyl aminopeptidase. Biochem Biophys Res Commun. 1991;178:1459-64 pubmed
    ..Further, pig intestinal prolyl aminopeptidase and pig kidney leucyl aminopeptidase were immunologically indistinguishable. These lines of evidence strongly suggest that prolyl aminopeptidase is identical with leucyl aminopeptidase. ..
  27. Sugimoto Y, Yatsunami K, Tsujimoto M, Khorana H, Ichikawa A. The amino acid sequence of a glutamic acid-rich protein from bovine retina as deduced from the cDNA sequence. Proc Natl Acad Sci U S A. 1991;88:3116-9 pubmed
    ..The retinal glutamic acid-rich protein showed homology with glutamic acid-rich proteins from bovine brain and the C-terminal region of mammalian neurofilaments. ..
  28. Muramatsu S, Mizuno T. Nucleotide sequence of the region encompassing the int gene of a cryptic prophage and the dna Y gene flanked by a curved DNA sequence of Escherichia coli K12. Mol Gen Genet. 1990;220:325-8 pubmed
    ..The results of sequencing further revealed that the int gene of a cryptic prophage, qsr', which has been shown to be present in the E. coli genome, is located next to the dna Y gene. ..
  29. Mizuno K, Nakamura T, Ohshima T, Tanaka S, Matsuo H. Yeast KEX2 genes encodes an endopeptidase homologous to subtilisin-like serine proteases. Biochem Biophys Res Commun. 1988;156:246-54 pubmed
    ..A putative membrane-spanning domain near the C-terminus was also detected. These facts indicate that the KEX2-encoded protein may function as a membrane-bound, subtilisin-like serine protease. ..
  30. Shimizu Nishikawa K, Kajiwara K, Kimura M, Katsuki M, Sugaya E. Cloning and expression of SEZ-6, a brain-specific and seizure-related cDNA. Brain Res Mol Brain Res. 1995;28:201-10 pubmed
    ..Based on these findings, it is evident that SEZ-6 encodes a novel type of protein which may be related to seizure. ..
  31. Nagahama M, Okagawa Y, Nakayama T, Nishioka E, Sakurai J. Site-directed mutagenesis of histidine residues in Clostridium perfringens alpha-toxin. J Bacteriol. 1995;177:1179-85 pubmed
    ..These results suggest that H-68, -126, and -136 residues bind an exchangeable and labile metal which is important for binding to membranes and that H-148 tightly binds one zinc atom which is essential for the active site of alpha-toxin. ..
  32. Honda H, Inazawa J, Nishida J, Yazaki Y, Hirai H. Molecular cloning, characterization, and chromosomal localization of a novel protein-tyrosine phosphatase, HPTP eta. Blood. 1994;84:4186-94 pubmed
    ..The chromosomal localization determined by fluorescence in situ hybridization showed that the HPTP eta gene was located at chromosome 11p11.2 on the short arm of chromosome 11, which is frequently lost or deleted in human carcinomas. ..
  33. Bae S, Yamaguchi Iwai Y, Ogawa E, Maruyama M, Inuzuka M, Kagoshima H, et al. Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1. Oncogene. 1993;8:809-14 pubmed
    ..A possible functional relationship between PEBP2 alpha and PEBP2 alpha B is discussed in relation to leukemogenic potential of AML1. ..
  34. Ueyama H, Inazawa J, Nishino H, Ohkubo I, Miwa T. FISH localization of human cytoplasmic actin genes ACTB to 7p22 and ACTG1 to 17q25 and characterization of related pseudogenes. Cytogenet Cell Genet. 1996;74:221-4 pubmed
    ..The gamma-actin-related pseudogenes were mapped by FISH to chromosomes 3q23 (ACTGP1), 20p13 (ACTGP3), and 6p21.1 (ACTGP9). ..
  35. Murata K, Masuda R. Gender determination of the Linne's two-toed sloth (Choloepus didactylus) using SRY amplified from hair. J Vet Med Sci. 1996;58:1157-9 pubmed
    ..The PCR method using hairs for sexing the sloth provides an advantageous tool for captive propagation plan in zoos. To the authors' knowledge, no report regarding SRY sequences in the order Xenarthra (Edentata) has been published...
  36. Naruse T, Ando R, Nose Y, Kagiya M, Ando H, Kawata H, et al. HLA-DRB4 genotyping by PCR-RFLP: diversity in the associations between HLA-DRB4 and DRB1 alleles. Tissue Antigens. 1997;49:152-9 pubmed
    ..These findings reveal extensive diversity of the HLA-DRB1 and -DRB4 haplotypes and may have important implications for HLA-disease associations and donor selection in unrelated transplantation. ..
  37. Tokunaga C, Tatematsu K, Kuroda S, Nakagawa N, Kikkawa U. Molecular cloning and characterization of RBCK2, a splicing variant of a RBCC family protein, RBCK1. FEBS Lett. 1998;435:11-5 pubmed
    ..These results suggest that RBCK2 may inhibit the transcriptional activity of RBCK1 probably through complex formation with RBCK1. ..
  38. Nishikawa Y, Xuan X, Otsuka H. Identification and characterization of the glycoprotein E and I genes of canine herpesvirus. Virus Res. 1998;56:77-92 pubmed
    ..The precursor of DFD-6 gI is modified to the mature form by N-linked glycosylation only in the presence of gE. ..
  39. Imada Y, Goji N, Ishikawa H, Kishima M, Sekizaki T. Truncated surface protective antigen (SpaA) of Erysipelothrix rhusiopathiae serotype 1a elicits protection against challenge with serotypes 1a and 2b in pigs. Infect Immun. 1999;67:4376-82 pubmed
    ..rhusiopathiae in swine and will be a useful tool for development of new types of vaccines and diagnostic tools for effective control of the disease...
  40. Iida A, Emi M, Matsuoka R, Hiratsuka E, Okui K, Ohashi H, et al. Identification of a gene disrupted by inv(11)(q13.5;q25) in a patient with left-right axis malformation. Hum Genet. 2000;106:277-87 pubmed
    ..Several hypotheses are discussed to explain the relationship between the chromosomal inversion and the accompanying phenotypes. ..
  41. Takada N, Fujita H, Yano Y, Ishiguro F, Iwasaki H, Masuzawa T. First records of tick-borne pathogens, Borrelia, and spotted fever group Rickettsiae in Okinawajima Island, Japan. Microbiol Immunol. 2001;45:163-5 pubmed
    ..These are the first reports of these pathogens on Okinawajima Island...
  42. Imamura T, Ohgane J, Ito S, Ogawa T, Hattori N, Tanaka S, et al. CpG island of rat sphingosine kinase-1 gene: tissue-dependent DNA methylation status and multiple alternative first exons. Genomics. 2001;76:117-25 pubmed
    ..Here, we identify rat Sphk1, using multiple alternative first exons for the subtypes, and demonstrate that there is a CpG island bearing T-DMR. ..
  43. Matsumori Y, Inai K, Yanase T, Ohashi S, Kato T, Yoshida K, et al. Serological and genetic characterization of newly isolated Peaton virus in Japan. Brief report. Arch Virol. 2002;147:401-10 pubmed
    ..6% between the Australian and Japanese strains. A phylogenetic analysis of the N protein sequence revealed that the PEA virus strains are closely related to Aino (AIN) virus and suggested reassortment events for PEA and AIN viruses. ..
  44. Yamaki M, Isono K, Takada Y, Abe K, Akasaka T, Tanzawa H, et al. The mouse Edr2 (Mph2) gene has two forms of mRNA encoding 90- and 36-kDa polypeptides. Gene. 2002;288:103-10 pubmed
    ..Therefore, the 36-kDa protein might function generally as a PcG protein. ..
  45. Ueno M, Nakayama H, Kajikawa S, Katayama K, Suzuki K, Doi K. Expression of ribosomal protein L4 (rpL4) during neurogenesis and 5-azacytidine (5AzC)-induced apoptotic process in the rat. Histol Histopathol. 2002;17:789-98 pubmed publisher
    ..From the results, it is suggested that rpL4 would have certain roles in cell proliferation and differentiation during neurogenesis, but have no roles in 5AzC-induced apoptosis in the fetal brain. ..
  46. Tsuji N, Suzuki K, Kasuga Aoki H, Isobe T, Arakawa T, Matsumoto Y. Mice intranasally immunized with a recombinant 16-kilodalton antigen from roundworm Ascaris parasites are protected against larval migration of Ascaris suum. Infect Immun. 2003;71:5314-23 pubmed
    ..The vaccinated mice showed a reduction by 58% in the recovery of challenged larvae compared to a nonvaccinated control. These results suggest the possibility of developing a mucosal vaccine for human and pig ascariasis. ..
  47. Hifumi E, Kondo H, Mitsuda Y, Uda T. Catalytic features of monoclonal antibody i41SL1-2 subunits. Biotechnol Bioeng. 2003;84:485-93 pubmed
    ..1 x 10(5) and 4.9 x 10(4) M(-1) min(-1), respectively. The first cleaved bond of the antigenic peptide by subunits of i41SL1-2 mAb was between Arg(1) and Ser(2) in the sequence of CDRL-1, suggesting a serine protease character. ..
  48. Nakashima N, Shibuya N. Multiple coding sequences for the genome-linked virus protein (VPg) in dicistroviruses. J Invertebr Pathol. 2006;92:100-4 pubmed
  49. Umemura M, Fujita M, Yoko o T, Fukamizu A, Jigami Y. Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramides. Mol Biol Cell. 2007;18:4304-16 pubmed
    ..Our results also indicate that mouse FRAG1 and C130090K23, which are homologous to Cwh43-N and -C, respectively, share these activities. ..
  50. Sasai N, Kato Y, Kimura G, Takeuchi T, Yamaguchi M. The Drosophila jumonji gene encodes a JmjC-containing nuclear protein that is required for metamorphosis. FEBS J. 2007;274:6139-51 pubmed
    ..These findings suggest that dJmj controls expression of developmentally important genes through modification of chromatin into a transcriptionally silenced state. ..
  51. Nomura T, Ishizuka A, Kishida K, Islam A, Endo T, Iwamura H, et al. Chromosome arm location of the genes for the biosynthesis of hordatines in barley. Genes Genet Syst. 2007;82:455-64 pubmed
    ..These facts suggest that the HvPrx7 gene on 2HL is not involved in the hordatine biosynthesis and that unidentified peroxidase gene responsible for the hordatine biosynthesis is located on 2HS in barley...
  52. Matsuda F, Inoue N, Maeda A, Cheng Y, Sai T, Gonda H, et al. Expression and function of apoptosis initiator FOXO3 in granulosa cells during follicular atresia in pig ovaries. J Reprod Dev. 2011;57:151-8 pubmed
    ..In conclusion, FOXO3 is expressed in porcine ovarian follicles and induces apoptosis in granulosa cells, suggesting that it is a candidate for the initiator of follicular atresia. ..
  53. Kawano T, Kataoka H, Nagasawa H, Isogai A, Suzuki A. cDNA cloning and sequence determination of the pheromone biosynthesis activating neuropeptide of the silkworm, Bombyx mori. Biochem Biophys Res Commun. 1992;189:221-6 pubmed
    ..Thus, the PBAN gene products construct a family of structurally related peptides and have various biological functions. ..
  54. Isomura T, Tamiya Koizumi K, Suzuki M, Yoshida S, Taniguchi M, Matsuyama M, et al. RFP is a DNA binding protein associated with the nuclear matrix. Nucleic Acids Res. 1992;20:5305-10 pubmed
    ..These results thus suggest that RFP may play a role in molecular processes which occur in the nuclear matrix. ..
  55. Sasatsu M, Shibata Y, Noguchi N, Kono M. High-level resistance to ethidium bromide and antiseptics in Staphylococcus aureus. FEMS Microbiol Lett. 1992;72:109-13 pubmed
    ..The efflux rate for EB of strains with duplicated ebr genes was twice the rate of strains with a single ebr gene. It was concluded that the duplication of ebr is responsible for the high-level resistance to EB and antiseptics. ..
  56. Kojima M, Minamino N, Kangawa K, Matsuo H. Cloning and sequence analysis of a cDNA encoding a precursor for rat C-type natriuretic peptide (CNP). FEBS Lett. 1990;276:209-13 pubmed
    ..By RNA blot analysis, rat CNP mRNA was found to be expressed exclusively in the brain, implying that CNP may function in the central nervous system as a neuropeptide. ..
  57. Lee W, Hatanaka M, Maki M. Multiple forms of rat calpastatin cDNA in the coding region of functionally unknown amino-terminal domain. Biochim Biophys Acta. 1992;1129:251-3 pubmed
    ..Both types of the rat sequence differed from the previously reported rat calpastatin which had additional deletions. The occurrence of multiple forms of calpastatin suggests alternative splicing in the functionally unknown domain. ..
  58. Yanagisawa S, Izui K, Yamaguchi Y, Shigesada K, Katsuki H. Further analysis of cDNA clones for maize phosphoenolpyruvate carboxylase involved in C4 photosynthesis. Nucleotide sequence of entire open reading frame and evidence for polyadenylation of mRNA at multiple sites in vivo. FEBS Lett. 1988;229:107-10 pubmed
    ..The sequencing of 3'-untranslated region of the clones revealed that the poly(A) tract is attached at multiple sites in vivo. ..
  59. Hirono H, Hayasaka K, Sato W, Takahashi T, Takada G. Isolation of cDNA encoding the human liver phosphorylase kinase alpha subunit (PHKA2) and identification of a missense mutation of the PHKA2 gene in a family with liver phosphorylase kinase deficiency. Biochem Mol Biol Int. 1995;36:505-11 pubmed
    ..We identified a missense mutation, a valine substitution for glycine at amino acid 193, in the PHKA2 gene of a family with XLG. ..
  60. Ogawa N, Noguchi K, Sawai H, Yamashita Y, Yompakdee C, Oshima Y. Functional domains of Pho81p, an inhibitor of Pho85p protein kinase, in the transduction pathway of Pi signals in Saccharomyces cerevisiae. Mol Cell Biol. 1995;15:997-1004 pubmed
    ..An in vitro assay showed that a glutathione S-transferase-Pho81p fusion protein inhibits the Pho85p protein kinase. Association of Pho81p with Pho85p or with the Pho80p-Pho85p complex was demonstrated by the two-hybrid system. ..
  61. Homma Y, Emori Y. A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities. EMBO J. 1995;14:286-91 pubmed
  62. Mikuni O, Ito K, Moffat J, Matsumura K, McCaughan K, Nobukuni T, et al. Identification of the prfC gene, which encodes peptide-chain-release factor 3 of Escherichia coli. Proc Natl Acad Sci U S A. 1994;91:5798-802 pubmed
    ..A completely null prfC mutation made by reverse genetics affected the cell growth under the limited set of physiological and strain conditions. ..
  63. Masuda Y, Ohtsubo E. Mapping and disruption of the chpB locus in Escherichia coli. J Bacteriol. 1994;176:5861-3 pubmed
    ..7 min on the map of Escherichia coli. We then constructed mutants with an insertion of a (cat) fragment within chpBK or chpBI on the E. coli chromosome. These mutants grew normally, indicating that chpB is dispensable for cell growth. ..
  64. Takahashi T, Shirasawa T. Molecular cloning of rat JAK3, a novel member of the JAK family of protein tyrosine kinases. FEBS Lett. 1994;342:124-8 pubmed
    ..Northern analysis indicated that the 4.0 kb mRNA was transcribed in a variety of tissues including spleen, lung, kidney and intestine. ..
  65. Matsunami H, Miyatani S, Inoue T, Copeland N, Gilbert D, Jenkins N, et al. Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene. J Cell Sci. 1993;106 ( Pt 1):401-9 pubmed
    ..Thus, the cell binding specificity of R-cadherin is entirely conserved between the two species, suggesting a conserved role for this protein in morphogenesis. We also located the mouse R-cadherin gene to chromosome 2. ..
  66. Shimizu E, Shirasawa H, Kodama K, Sato T, Simizu B. Expression, regulation and polymorphism of the mxi1 genes. Gene. 1996;176:45-8 pubmed
    ..We have also found an AAAAC polymorphic repeat in the 3' non-coding region of the human mxi1 cDNAs and a difference between the mxi1 mRNA half-lives in some different cell lines. ..
  67. Itoh T, Tanaka T, Nagai R, Kamiya T, Sawayama T, Nakayama T, et al. Genomic organization and mutational analysis of HERG, a gene responsible for familial long QT syndrome. Hum Genet. 1998;102:435-9 pubmed
    ..Each mutation was present in affected relatives of the respective proband. This work should increase the efficiency of screening mutations associated with HERG. ..
  68. Yoshida K, Yoshitomo Nakagawa K, Seki N, Sasaki M, Sugano S. Cloning, expression analysis, and chromosomal localization of BH-protocadherin (PCDH7), a novel member of the cadherin superfamily. Genomics. 1998;49:458-61 pubmed
    ..The BH-Pcdh gene was localized to human chromosome 4p15. Interestingly, 4p15 is a region of loss of heterozygosity in some head and neck squamous cell carcinomas. ..
  69. Matsushika A, Mizuno T. Mutational analysis of the histidine-containing phosphotransfer (HPt) signaling domain of the ArcB sensor in Escherichia coli. Biosci Biotechnol Biochem. 1998;62:2236-8 pubmed
    ..These ArcBc mutants were characterized and evaluated, based on the in vivo ability to signal the OmpR receiver via trans-phosphorylation. ..
  70. Hirahara Y, Tsuda M, Wada Y, Honke K. cDNA cloning, genomic cloning, and tissue-specific regulation of mouse cerebroside sulfotransferase. Eur J Biochem. 2000;267:1909-17 pubmed
    ..These observations suggest that the tissue-specific expression of the CST gene is explained by alternative usage of multiple 5'-UTR exons flanked with tissue-specific promoters. ..
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