Experts and Doctors on mitochondrial proteins in Mexico


Locale: Mexico
Topic: mitochondrial proteins

Top Publications

  1. De Los Rios Castillo D, Zarco Zavala M, Olvera Sánchez S, Pardo J, Juárez O, Martinez F, et al. Atypical cristae morphology of human syncytiotrophoblast mitochondria: role for complex V. J Biol Chem. 2011;286:23911-9 pubmed publisher
    ..The possible relationship between cristae architecture and the physiological function of the syncytiotrophoblast mitochondria is discussed. ..
  2. Ruiz Ramírez A, Chávez Salgado M, Peñeda Flores J, Zapata E, Masso F, El Hafidi M. High-sucrose diet increases ROS generation, FFA accumulation, UCP2 level, and proton leak in liver mitochondria. Am J Physiol Endocrinol Metab. 2011;301:E1198-207 pubmed publisher
    ..However, in whole liver these adaptive mechanisms of the mitochondria were inefficient at counteracting redox imbalances and inhibiting oxidative stress outside of the mitochondria. ..
  3. Martinez Velazquez M, Melendez Zajgla J, Maldonado V. Apoptosis induced by cAMP requires Smac/DIABLO transcriptional upregulation. Cell Signal. 2007;19:1212-20 pubmed
    ..These results show that cAMP is an important modulator of the apoptotic threshold in cancer cell by means of regulating Smac/DIABLO expression. ..
  4. Ceballos Cancino G, Espinosa M, Maldonado V, Melendez Zajgla J. Regulation of mitochondrial Smac/DIABLO-selective release by survivin. Oncogene. 2007;26:7569-75 pubmed
    ..These results provide an explanation for the observed differences in the release of mitochondrial intermembrane proteins in various apoptotic models and present a new mechanism for the anti-apoptotic effects of survivin in cancer cells. ..
  5. Tavares Carreón F, Camacho Villasana Y, Zamudio Ochoa A, Shingu Vazquez M, Torres Larios A, Perez Martinez X. The pentatricopeptide repeats present in Pet309 are necessary for translation but not for stability of the mitochondrial COX1 mRNA in yeast. J Biol Chem. 2008;283:1472-9 pubmed
    ..Our results show that the RNA metabolism function of Pet309 is found in at least two separate domains of the protein. ..
  6. Pruefer F, Lizarraga F, Maldonado V, Melendez Zajgla J. Participation of Omi Htra2 serine-protease activity in the apoptosis induced by cisplatin on SW480 colon cancer cells. J Chemother. 2008;20:348-54 pubmed
    ..05, but not to 5-FU p=0.49. From these experiments we show that Omi/Htra2 serine protease activity participates in the cell death induced by CDDP but not of 5-FU in colon cancer cells. ..
  7. Luévano Martínez L, Moyano E, de Lacoba M, Rial E, Uribe Carvajal S. Identification of the mitochondrial carrier that provides Yarrowia lipolytica with a fatty acid-induced and nucleotide-sensitive uncoupling protein-like activity. Biochim Biophys Acta. 2010;1797:81-8 pubmed publisher
    ..It is concluded that the XM_503525 gene from Y. lipolytica encodes for an oxaloacetate carrier although, remarkably, it also displays an uncoupling activity stimulated by fatty acids and inhibited by nucleotides. ..
  8. Colón M, Hernandez F, Lopez K, Quezada H, González J, López G, et al. Saccharomyces cerevisiae Bat1 and Bat2 aminotransferases have functionally diverged from the ancestral-like Kluyveromyces lactis orthologous enzyme. PLoS ONE. 2011;6:e16099 pubmed publisher
    ..lactis has been distributed in the two paralogous genes present in S. cerevisiae, and whether this conservation has impacted S. cerevisiae metabolism...
  9. Guerrero Castillo S, Araiza Olivera D, Cabrera Orefice A, Espinasa Jaramillo J, Gutiérrez Aguilar M, Luévano Martínez L, et al. Physiological uncoupling of mitochondrial oxidative phosphorylation. Studies in different yeast species. J Bioenerg Biomembr. 2011;43:323-31 pubmed publisher
    ..The variety of energy dissipating systems in eukaryote species is probably designed to control ROS production in the different environments where each species lives. ..

More Information


  1. Cabrera Orefice A, Chiquete Felix N, Espinasa Jaramillo J, Rosas Lemus M, Guerrero Castillo S, Pena A, et al. The branched mitochondrial respiratory chain from Debaryomyces hansenii: components and supramolecular organization. Biochim Biophys Acta. 2014;1837:73-84 pubmed publisher
    ..Binding of the alternative enzymes to supercomplexes was not detected. This is the first report on the structure and organization of the mitochondrial respiratory chain from D. hansenii. ..
  2. De Silva D, Poliquin S, Zeng R, Zamudio Ochoa A, Marrero N, Perez Martinez X, et al. The DEAD-box helicase Mss116 plays distinct roles in mitochondrial ribogenesis and mRNA-specific translation. Nucleic Acids Res. 2017;45:6628-6643 pubmed publisher
    ..Overall, we conclude that the different functions of Mss116 in the biogenesis and functioning of the mitochondrial translation machinery depend on Mss116 interplay with its protein cofactors. ..
  3. Peralta Castro A, Baruch Torres N, Brieba L. Plant organellar DNA primase-helicase synthesizes RNA primers for organellar DNA polymerases using a unique recognition sequence. Nucleic Acids Res. 2017;45:10764-10774 pubmed publisher
    ..This mechanism contrasts to lagging-strand DNA replication in metazoan mitochondria, in which transcripts synthesized by mitochondrial RNA polymerase prime mitochondrial DNA polymerase ?. ..
  4. Guerrero Castillo S, Vázquez Acevedo M, Gonzalez Halphen D, Uribe Carvajal S. In Yarrowia lipolytica mitochondria, the alternative NADH dehydrogenase interacts specifically with the cytochrome complexes of the classic respiratory pathway. Biochim Biophys Acta. 2009;1787:75-85 pubmed publisher
    ..To our knowledge, this is the first evidence of supercomplex formation in Y. lipolytica mitochondria and also, the first description of a specific association between an alternative NADH dehydrogenase and the classic cytochrome pathway. ..
  5. Mayorga J, Camacho Villasana Y, Shingú Vázquez M, García Villegas R, Zamudio Ochoa A, García Guerrero A, et al. A Novel Function of Pet54 in Regulation of Cox1 Synthesis in Saccharomyces cerevisiae Mitochondria. J Biol Chem. 2016;291:9343-55 pubmed publisher
    ..Pet54 may play a role in Mss51 hemylation/conformational change necessary for translational activity. Moreover, Pet54 physically interacts with the COX1 mRNA, and this binding was independent of the presence of Mss51. ..