Experts and Doctors on messenger rna in United States

Summary

Locale: United States
Topic: messenger rna

Top Publications

  1. Kim H, Nagalla S, Oh Y, Wilson E, Roberts C, Rosenfeld R. Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily. Proc Natl Acad Sci U S A. 1997;94:12981-6 pubmed
    ..These genes, along with those encoding the high-affinity IGFBPs 1-6, together constitute an IGFBP superfamily whose products function in IGF-dependent or IGF-independent modes to regulate normal and neoplastic cell growth. ..
  2. Tu Y, Li F, Wu C. Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways. Mol Biol Cell. 1998;9:3367-82 pubmed
    ..These results identify a novel Nck-related SH2- and SH3-domain-containing protein and suggest that it may function as an adaptor protein connecting the growth factor receptor-signaling pathways with the integrin-signaling pathways. ..
  3. Kalajzic I, Braut A, Guo D, Jiang X, Kronenberg M, Mina M, et al. Dentin matrix protein 1 expression during osteoblastic differentiation, generation of an osteocyte GFP-transgene. Bone. 2004;35:74-82 pubmed
    ..Generation of this transgenic model will facilitate studies of gene expression and biological functions in these terminally differentiated bone cells. ..
  4. Lin T, Chang C. Cloning and characterization of TDD5, an androgen target gene that is differentially repressed by testosterone and dihydrotestosterone. Proc Natl Acad Sci U S A. 1997;94:4988-93 pubmed
  5. Campbell W, Weiner I, Wingo C, Cain B. H-K-ATPase in the RCCT-28A rabbit cortical collecting duct cell line. Am J Physiol. 1999;276:F237-45 pubmed
    ..Such findings constitute very strong evidence for expression of the HKalpha2c subunit in vivo. The results suggest that the rabbit kidney and RCCT-28A cells express at least three distinct H-K-ATPases. ..
  6. Huang H, Reed C, Zhang J, Shridhar V, Wang L, Smith D. Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells. Cancer Res. 1999;59:2981-8 pubmed
    ..Our data demonstrate that the histone hyperacetylation signaling pathway is activated during NaBu-mediated differentiation of PC-3 cells, and the new gene, CPA3, is involved in this pathway. ..
  7. Xin H, Lin W, Sumanasekera W, Zhang Y, Wu X, Wang Z. The human RAD18 gene product interacts with HHR6A and HHR6B. Nucleic Acids Res. 2000;28:2847-54 pubmed
    ..Consistent with its role as a fundamental lesion bypass protein, the RAD18 gene is ubiquitously expressed in various human tissues. ..
  8. Biesiadecki B, Jin J. Exon skipping in cardiac troponin T of turkeys with inherited dilated cardiomyopathy. J Biol Chem. 2002;277:18459-68 pubmed publisher
  9. Voge J, Aad P, Santiago C, Goad D, Malayer J, Allen D, et al. Effect of insulin-like growth factors (IGF), FSH, and leptin on IGF-binding-protein mRNA expression in bovine granulosa and theca cells: quantitative detection by real-time PCR. Peptides. 2004;25:2195-203 pubmed

More Information

Publications248 found, 100 shown here

  1. Gabrielides C, McCormack A, Hunt D, Christakos S. Brain calbindin-D28k and an Mr 29,000 calcium binding protein in cerebellum are different but related proteins: evidence obtained from sequence analysis by tandem mass spectrometry. Biochemistry. 1991;30:656-62 pubmed
    ..abstract truncated at 250 words) ..
  2. Marcelino J, Carpten J, Suwairi W, Gutierrez O, Schwartz S, Robbins C, et al. CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat Genet. 1999;23:319-22 pubmed
    ..The similarity of CACP sequence to that of other protein families and the expression of CACP in non-skeletal tissues suggest it may have diverse biological activities. ..
  3. Abboud M, Taylor E, Habib D, Dantzler Johnson T, Jackson S, Xu F, et al. Elevated serum and bronchoalveolar lavage fluid levels of interleukin 8 and granulocyte colony-stimulating factor associated with the acute chest syndrome in patients with sickle cell disease. Br J Haematol. 2000;111:482-90 pubmed
    ..These findings suggest that IL-8 and G-CSF may play a role in the development of the ACS and the complications associated with it. ..
  4. Dong Y, Yang H, Elliott M, McMasters K. Increased mdm-2 expression in a p53-independent manner blocks UV-induced cell cycle arrest and apoptosis in human osteosarcoma cells. Tumour Biol. 2003;24:130-9 pubmed
    ..Furthermore, increased expression of MDM-2 in OsACL cells following UV irradiation appears to be related to P53-independent mechanisms. ..
  5. Maquat L. Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics. Nat Rev Mol Cell Biol. 2004;5:89-99 pubmed
    ..The acquisition and loss of mRNA-associated proteins accompanies the transition from the pioneer round to subsequent rounds of translation, and from translational competence to substrate for nonsense-mediated mRNA decay. ..
  6. Bhalla T, Rosenthal J, Holmgren M, Reenan R. Control of human potassium channel inactivation by editing of a small mRNA hairpin. Nat Struct Mol Biol. 2004;11:950-6 pubmed
    ..These results suggest an ancient and key regulatory role for this residue in K(V) channels. ..
  7. Das N, Wang J, Dey S. Uterine preparation for implantation in the mouse is associated with coordinate expression of estrogen-responsive finger protein and estrogen receptor. Mol Reprod Dev. 1997;46:499-506 pubmed
    ..In contrast, discoordinate expression of Efp and ER during the postimplantation period (days 5-8) suggests primary dependence of the decidualization process on P4, but not estrogen. ..
  8. He Q, Luo X, Huang Y, Sheikh M. Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells. Oncogene. 2002;21:6032-40 pubmed
    ..In conclusion, the data presented herein form the basis of future in-depth studies to further explore the utility of Apo2L/TRAIL and NSAIDs, in combination, as a novel cancer preventive/therapeutic strategy. ..
  9. Provenzano P, Alejandro Osorio A, Valhmu W, Jensen K, Vanderby R. Intrinsic fibroblast-mediated remodeling of damaged collagenous matrices in vivo. Matrix Biol. 2005;23:543-55 pubmed
    ..As such, this system provides unique insight into acute tissue damage and offers a potentially powerful model to examine fibroblast behavior. ..
  10. Spruill L, Lowry A, Stroud R, Squires C, Mains I, Flack E, et al. Membrane-type-1 matrix metalloproteinase transcription and translation in myocardial fibroblasts from patients with normal left ventricular function and from patients with cardiomyopathy. Am J Physiol Cell Physiol. 2007;293:C1362-73 pubmed
    ..These phenotypic changes in DCM fibroblasts may provide the basis for developing cell specific pharmacological targets for control of MT1-MMP expression. ..
  11. Wilson C, Akhter S, Mayer C, Kc P, Balan K, Ernsberger P, et al. Allergic lung inflammation affects central noradrenergic control of cholinergic outflow to the airways in ferrets. J Appl Physiol (1985). 2007;103:2095-104 pubmed
  12. Mukhopadhyay P, Horn K, Greene R, Michele Pisano M. Prenatal exposure to environmental tobacco smoke alters gene expression in the developing murine hippocampus. Reprod Toxicol. 2010;29:164-75 pubmed publisher
  13. Chung M, Nascone Yoder N, Grover S, Drysdale T, Wallingford J. Direct activation of Shroom3 transcription by Pitx proteins drives epithelial morphogenesis in the developing gut. Development. 2010;137:1339-49 pubmed publisher
    ..More generally, these results provide a foundation for deciphering the transcriptional network that underlies epithelial cell shape change in developing vertebrates...
  14. Weinmann A, Bartley S, Zhang T, Zhang M, Farnham P. Use of chromatin immunoprecipitation to clone novel E2F target promoters. Mol Cell Biol. 2001;21:6820-32 pubmed
  15. Providence K, Higgins P. PAI-1 expression is required for epithelial cell migration in two distinct phases of in vitro wound repair. J Cell Physiol. 2004;200:297-308 pubmed
    ..These findings validate use of the present keratinocyte model to investigate injury-related controls on PAI-1 gene regulation and, collectively, implicate participation of PAI-1 in two distinct phases of epidermal wound repair. ..
  16. Zhang J, Blanco J. Identification of the promoter of human carbonyl reductase 3 (CBR3) and impact of common promoter polymorphisms on hepatic CBR3 mRNA expression. Pharm Res. 2009;26:2209-15 pubmed publisher
    ..In line, hepatic CBR3 mRNA levels were not associated with CBR3 -725T>C and CBR3 -326T>A genotype status. These studies provide the first insights into the regulation and variable hepatic expression of polymorphic CBR3. ..
  17. Banks J, Kealoha B, Linial M. An Mpsi-containing heterologous RNA, but not env mRNA, is efficiently packaged into avian retroviral particles. J Virol. 1999;73:8926-33 pubmed
    ..Finally, deletion of sequences from the 3' end of MPsi was found to reduce the packaging efficiency of heterologous RNAs. ..
  18. Rush J, Laughlin M, Woodman C, Price E. SOD-1 expression in pig coronary arterioles is increased by exercise training. Am J Physiol Heart Circ Physiol. 2000;279:H2068-76 pubmed
    ..dependent dilation previously observed in EX porcine coronary arterioles by improving management of superoxide in the vascular cell environment, thus prolonging the biological half-life of NO...
  19. Zimowska G, Paddy M. Structures and dynamics of Drosophila Tpr inconsistent with a static, filamentous structure. Exp Cell Res. 2002;276:223-32 pubmed
  20. Hu X, Bulger M, Roach J, Eszterhas S, Olivier E, Bouhassira E, et al. Promoters of the murine embryonic beta-like globin genes Ey and betah1 do not compete for interaction with the beta-globin locus control region. Proc Natl Acad Sci U S A. 2003;100:1111-5 pubmed
    ..The implication of these findings for models of beta-globin gene expression are discussed. ..
  21. Lim K, Lang T, Lam V, Yin J. Model-based design of growth-attenuated viruses. PLoS Comput Biol. 2006;2:e116 pubmed
    ..Such models will facilitate the engineering of new live-virus vaccines by linking genomic manipulations to controlled changes in virus gene-expression and growth. ..
  22. Nesic D, Zhang J, Maquat L. Lack of an effect of the efficiency of RNA 3'-end formation on the efficiency of removal of either the final or the penultimate intron in intact cells. Mol Cell Biol. 1995;15:488-96 pubmed
    ..If so, then the independence of TPI RNA splicing on 3'-end formation may be rationalized by the lack of a comparable function. ..
  23. Han T, De Vries G. Organizational effects of testosterone, estradiol, and dihydrotestosterone on vasopressin mRNA expression in the bed nucleus of the stria terminalis. J Neurobiol. 2003;54:502-10 pubmed
  24. Nervina J, Tetradis S, Huang Y, Harrison D, Molina C, Kream B. Expression of inducible cAMP early repressor is coupled to the cAMP-protein kinase A signaling pathway in osteoblasts. Bone. 2003;32:483-90 pubmed
    ..Finally, PTH, FSK, and PTHrP induced ICER in cultured mouse calvariae and osteoblastic ROS 17/2.8, UMR-106, and Pyla cells. We conclude that ICER expression in osteoblasts requires activation of the cAMP-PKA signaling pathway. ..
  25. Ojano Dirain C, Toyomizu M, Wing T, Cooper M, Bottje W. Gene expression in breast muscle and duodenum from low and high feed efficient broilers. Poult Sci. 2007;86:372-81 pubmed
    ..The differences that were observed may also reflect inherent metabolic and gene regulation differences between tissues. ..
  26. Takahara K, Lyons G, Greenspan D. Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues. J Biol Chem. 1994;269:32572-8 pubmed
    ..In situ hybridizations found punctate signals for all three forms localized to trophoblast giant cells in 17.5-day mouse placenta, with highest levels of expression, especially for BMP-1, near the maternal interface. ..
  27. Lineaweaver W, Lei M, Mustain W, Oswald T, Cui D, Zhang F. Vascular endothelium growth factor, surgical delay, and skin flap survival. Ann Surg. 2004;239:866-73; discussion 873-5 pubmed
    ..These results correlate with previous studies showing the preoperative injection of VEGF increases skin paddle survival. VEGF may be an important element in the delay phenomenon and may be an agent for pharmacological delay. ..
  28. Burkey T, Skjolaas K, Dritz S, Minton J. Expression of Toll-like receptors, interleukin 8, macrophage migration inhibitory factor, and osteopontin in tissues from pigs challenged with Salmonella enterica serovar Typhimurium or serovar Choleraesuis. Vet Immunol Immunopathol. 2007;115:309-19 pubmed
    ..However, although statistically significant effects of bacterial feeding were observed in selected tissues for some targets, most changes in mRNA were generally incremental in magnitude...
  29. Onaivi E. Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain. Neuropsychobiology. 2006;54:231-46 pubmed
    ..This multifocal expression of iCB2 in the brain suggests that CB2 receptors may play broader roles than previously anticipated and may therefore be exploited as new targets in the treatment of depression and substance abuse. ..
  30. Chen L, Lo C, Numann R, Cuddy M. Characterization of the human and rat phospholemman (PLM) cDNAs and localization of the human PLM gene to chromosome 19q13.1. Genomics. 1997;41:435-43 pubmed
    ..The high degree of sequence and functional conservation among the mammalian PLM proteins indicates that this gene is conserved throughout evolution. ..
  31. Meller V. Initiation of dosage compensation in Drosophila embryos depends on expression of the roX RNAs. Mech Dev. 2003;120:759-67 pubmed
    ..Either roX transcript can support X-localization of the complex, but localization is delayed in roX1 mutants until roX2 expression. These results support a model for the ordered assembly of the complex in embryos. ..
  32. D Souza S, Daikoku T, Farach Carson M, Carson D. Heparanase expression and function during early pregnancy in mice. Biol Reprod. 2007;77:433-41 pubmed
    ..Collectively, these results indicate that HPSE plays a role in blastocyst implantation and complements previous studies showing a role for HS-dependent interactions in this process. ..
  33. Ursic D, Himmel K, Gurley K, Webb F, Culbertson M. The yeast SEN1 gene is required for the processing of diverse RNA classes. Nucleic Acids Res. 1997;25:4778-85 pubmed
    ..We propose that Sen1 is an RNA helicase acting on a wide range of RNA classes. Its effects on the targeted RNAs in turn enable ribonuclease activity. ..
  34. Smith N, Dong Y, Lian J, Pratap J, Kingsley P, Van Wijnen A, et al. Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005;203:133-43 pubmed
  35. Nevin K, Kim B, Glaven R, Johnson J, Woodard T, Methe B, et al. Anode biofilm transcriptomics reveals outer surface components essential for high density current production in Geobacter sulfurreducens fuel cells. PLoS ONE. 2009;4:e5628 pubmed publisher
    ..sulfurreducens biofilms to electrodes. ..
  36. Hao K, Chudin E, McElwee J, Schadt E. Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies. BMC Genet. 2009;10:27 pubmed publisher
    ..Furthermore, cis-eQTL mapping using dense SNP set derived from imputation achieves great resolution, and locate associate peak closer to causal variants than conventional approach. ..
  37. Unlap M, Peti Peterdi J, Bell P. Cloning of mesangial cell Na(+)/Ca(2+) exchangers from Dahl/Rapp salt-sensitive/resistant rats. Am J Physiol Renal Physiol. 2000;279:F177-84 pubmed
    ..the S rat. Lack of PKC activation of SNCX1 may contribute to a dysregulation of intracellular Ca(2+) concentration and enhanced renal vasoreactivity in this model of hypertension...
  38. Marian M, Mukhopadhyay P, Borchman D, Tang D, Paterson C. Regulation of sarco/endoplasmic and plasma membrane calcium ATPase gene expression by calcium in cultured human lens epithelial cells. Cell Calcium. 2007;41:87-95 pubmed
    ..Considering the harmful effects of increased intracellular calcium levels, the upregulation of both SERCA and PMCA pumps suggests it is a compensatory mechanism to restore the calcium concentration to the physiological resting level. ..
  39. Miazga C, McLaughlin K. Coordinating the timing of cardiac precursor development during gastrulation: a new role for Notch signaling. Dev Biol. 2009;333:285-96 pubmed publisher
    ..Taken together, these findings provide strong evidence for a novel role for Notch signaling in regulating the timing of heart field specification during early cardiogenesis. ..
  40. Smith D, Kitner J, Norbeck A, Clauss T, Lipton M, Schwalbach M, et al. Transcriptional and translational regulatory responses to iron limitation in the globally distributed marine bacterium Candidatus pelagibacter ubique. PLoS ONE. 2010;5:e10487 pubmed publisher
    ..We propose a model in which the RNA-binding activity of CspE and CspL selectively enables protein synthesis of the iron acquisition protein SfuC during transient growth-limiting episodes of iron scarcity...
  41. Romero M, Boron W. Electrogenic Na+/HCO3- cotransporters: cloning and physiology. Annu Rev Physiol. 1999;61:699-723 pubmed
    ..For example, NBC occurs in pancreas, prostate, brain, heart, small and large intestine, stomach, and epididymis. Finally, there are at least two genes that encode NBC proteins. Possible future directions of research are discussed. ..
  42. Selberg K, Staples C, Luchini N, Badinga L. Dietary trans octadecenoic acids upregulate the liver gene encoding peroxisome proliferator-activated receptor-alpha in transition dairy cows. J Dairy Res. 2005;72:107-14 pubmed
    ..Results indicate that dietary trans fatty acids may affect liver lipid metabolism in post-partum dairy cows through alterations in PPARalpha gene expression. ..
  43. Zager R, Johnson A, Lund S, Randolph Habecker J. Toll-like receptor (TLR4) shedding and depletion: acute proximal tubular cell responses to hypoxic and toxic injury. Am J Physiol Renal Physiol. 2007;292:F304-12 pubmed
    ..Rapid postinjury urinary TLR4 excretion suggests its potential utility as a "biomarker" of impending ARF...
  44. Krzysik Walker S, Ocón Grove O, Maddineni S, Hendricks G, Ramachandran R. Identification of calcitonin expression in the chicken ovary: influence of follicular maturation and ovarian steroids. Biol Reprod. 2007;77:626-35 pubmed
    ..We conclude that ovarian CALCA is possibly involved in regulating follicular maturation in the chicken ovary. ..
  45. Aleksunes L, Reisman S, Yeager R, Goedken M, Klaassen C. Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice. J Pharmacol Exp Ther. 2010;333:140-51 pubmed publisher
    ..Collectively, these data indicate that the absence of Nrf2 worsens hyperglycemia in type I diabetic mice and Nrf2 may represent a therapeutic target for reducing circulating glucose levels. ..
  46. Wang Y, Kobori J, Hood L. The ht beta gene encodes a novel CACCC box-binding protein that regulates T-cell receptor gene expression. Mol Cell Biol. 1993;13:5691-701 pubmed
    ..These results suggest that the CACCC box-binding protein may have an important regulatory function for TCR gene expression in alpha beta T cells versus gamma delta T cells. ..
  47. Prabhu S, Wang G, Luo J, Gu Y, Ping P, Chandrasekar B. Beta-adrenergic receptor blockade modulates Bcl-X(S) expression and reduces apoptosis in failing myocardium. J Mol Cell Cardiol. 2003;35:483-93 pubmed
    ..beta-AR blockade in HF reduces myocardial apoptosis; attenuation of Bcl-X(S) expression may be one mechanism underlying this effect. ..
  48. Xu L, Renaud L, Muller J, Baicu C, Bonnema D, Zhou H, et al. Regulation of Ncx1 expression. Identification of regulatory elements mediating cardiac-specific expression and up-regulation. J Biol Chem. 2006;281:34430-40 pubmed
    ..This work is the first in vivo study that demonstrates which cis elements are important for Ncx1 regulation. ..
  49. Martins Green M, Bixby J, Yamamoto T, Graf T, Sudol M. Tissue specific expression of Yrk kinase: implications for differentiation and inflammation. Int J Biochem Cell Biol. 2000;32:351-64 pubmed
  50. Spangenburg E, Abraha T, Childs T, Pattison J, Booth F. Skeletal muscle IGF-binding protein-3 and -5 expressions are age, muscle, and load dependent. Am J Physiol Endocrinol Metab. 2003;284:E340-50 pubmed
  51. Schnabolk G, Gupta B, Mulgaonkar A, Kulkarni M, Sweet D. Organic anion transporter 6 (Slc22a20) specificity and Sertoli cell-specific expression provide new insight on potential endogenous roles. J Pharmacol Exp Ther. 2010;334:927-35 pubmed publisher
  52. Sen A, O Malley K, Wang Z, Raj G, DeFranco D, Hammes S. Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells. J Biol Chem. 2010;285:28787-95 pubmed publisher
    ..Thus, paxillin may prove to be a novel diagnostic or therapeutic target in prostate cancer. ..
  53. Yan T, Riggs B, Boyle W, Khosla S. Regulation of osteoclastogenesis and RANK expression by TGF-beta1. J Cell Biochem. 2001;83:320-5 pubmed
    ..These data thus indicate that TGF-beta directly stimulates osteoclastic differentiation, and this is accompanied by increased RANK mRNA and protein expression. ..
  54. Cheng X, Yang L, He P, Li R, Shen Y. Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non-demented patients. J Alzheimers Dis. 2010;19:621-30 pubmed publisher
    ..01). These studies reveal a novel observation of abnormal TNF receptor activation in AD brains. Differential TNF receptor protein levels and binding affinities suggest distinct pathogenic mechanisms of neurodegeneration in the AD brain...
  55. Wang X, O Hanlon T, Young R, Lau J. Rat beta-galactoside alpha 2,6-sialyltransferase genomic organization: alternate promoters direct the synthesis of liver and kidney transcripts. Glycobiology. 1990;1:25-31 pubmed
    ..Together, the data implicate multiple promoters as a principle mechanism in the generation of kidney and liver gene product diversity in sialyltransferase expression. ..
  56. Williams K. The tmRNA website. Nucleic Acids Res. 2000;28:168 pubmed
    ..Updates are very frequent. The tmRNA Website has a new URL: http:www.indiana.edu/tmrna ..
  57. Vesosky B, Rottinghaus E, Stromberg P, Turner J, Beamer G. CCL5 participates in early protection against Mycobacterium tuberculosis. J Leukoc Biol. 2010;87:1153-65 pubmed publisher
    ..Overall, these results contribute to a model of M.tb granuloma formation dependent on temporal regulation of chemokines rather than on redundant or promiscuous interactions. ..
  58. Primorac D, Stover M, Clark S, Rowe D. Molecular basis of nanomelia, a heritable chondrodystrophy of chicken. Matrix Biol. 1994;14:297-305 pubmed
    ..The mutation creates a unique BasBI restriction site which readily distinguishes the mutant and wild-type alleles. ..
  59. Flickinger T, Salz H. The Drosophila sex determination gene snf encodes a nuclear protein with sequence and functional similarity to the mammalian U1A snRNP protein. Genes Dev. 1994;8:914-25 pubmed
    ..These studies provide the first demonstration, in a multicellular organism, that mutations in a U1 snRNP protein alter splicing in vivo. ..
  60. Eblen A, Bao S, Lei Z, Nakajima S, Rao C. The presence of functional luteinizing hormone/chorionic gonadotropin receptors in human sperm. J Clin Endocrinol Metab. 2001;86:2643-8 pubmed
    ..Now that the functional LH/hCG receptors are found in human sperm, it is important to determine whether hCG treatment could improve the outcome of infertility procedures. ..
  61. Fallavollita J, Jacob S, Young R, Canty J. Regional alterations in SR Ca(2+)-ATPase, phospholamban, and HSP-70 expression in chronic hibernating myocardium. Am J Physiol. 1999;277:H1418-28 pubmed
    ..This supports the hypothesis that SR dysfunction from reversible ischemia may be an early defect in the progression of left ventricular dysfunction. ..
  62. Okada H, Kimura M, Tan D, Fujiwara K, Igarashi J, Makuuchi M, et al. Frequent trefoil factor 3 (TFF3) overexpression and promoter hypomethylation in mouse and human hepatocellular carcinomas. Int J Oncol. 2005;26:369-77 pubmed
  63. Banerjee H, Palenchar J, Lukaszewicz M, Bojarska E, Stepinski J, Jemielity J, et al. Identification of the HIT-45 protein from Trypanosoma brucei as an FHIT protein/dinucleoside triphosphatase: substrate specificity studies on the recombinant and endogenous proteins. RNA. 2009;15:1554-64 pubmed publisher
    ..This hypermethylated dinucleotide is unique to trypanosomes and may be an intermediate in the decay of cap 4, i.e., m(7)Gpppm(3)(N6, N6, 2'O)Apm(2'O)Apm(2'O)Cpm(2)(N3, 2'O)U, that occurs in these organisms. ..
  64. Behrendt Adam C, Adams M, Simpson K, McDowell K. Oxytocin-neurophysin I mRNA abundance in equine uterine endometrium. Domest Anim Endocrinol. 1999;16:183-92 pubmed
    ..Uterine oxytocin may be involved in regulation of reproductive tract function during the estrous cycle and/or establishment of pregnancy in horses. ..
  65. Kluk M, Hla T. Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration. Circ Res. 2001;89:496-502 pubmed
    ..Since EDG-1 is expressed in the pup-intimal phenotype of VSMCs, S1P signaling via EDG-1 may play a role in vascular diseases in which the proliferation and migration of VSMCs are dysregulated. ..
  66. Kalin N, Shelton S, Engeland C, Haraldsson H, Marucha P. Stress decreases, while central nucleus amygdala lesions increase, IL-8 and MIP-1alpha gene expression during tissue healing in non-human primates. Brain Behav Immun. 2006;20:564-8 pubmed publisher
    ..Because of brain and behavioral similarities between rhesus monkeys and humans, these results are particularly relevant to understanding brain mechanisms that influence healing in humans...
  67. Chen B, Overgaard M, Bale L, Resch Z, Christiansen M, Oxvig C, et al. Molecular regulation of the IGF-binding protein-4 protease system in human fibroblasts: identification of a novel inducible inhibitor. Endocrinology. 2002;143:1199-205 pubmed
    ..These findings expand our understanding of the IGFBP-4 protease system and suggest an additional level of local cell growth control. ..
  68. Znoiko S, Rohrer B, Lu K, Lohr H, Crouch R, Ma J. Downregulation of cone-specific gene expression and degeneration of cone photoreceptors in the Rpe65-/- mouse at early ages. Invest Ophthalmol Vis Sci. 2005;46:1473-9 pubmed
    ..Early administration of 9- or 11-cis retinal can partially prevent cone loss, suggesting that the absence of 11-cis chromophore may be responsible for the early cone degeneration. ..
  69. Mukherjee I, Campbell N, Ash J, Connolly E. Expression profiling of the Arabidopsis ferric chelate reductase (FRO) gene family reveals differential regulation by iron and copper. Planta. 2006;223:1178-90 pubmed
    ..Together our results suggest that FRO family members function in metal ion homeostasis in a variety of locations in the plant. ..
  70. Eid G, French D, Lundgren A, Barbet A, McElwain T, Palmer G. Expression of major surface protein 2 antigenic variants during acute Anaplasma marginale rickettsemia. Infect Immun. 1996;64:836-41 pubmed
  71. Zou Z, Jiang H. Manduca sexta serpin-6 regulates immune serine proteinases PAP-3 and HP8. cDNA cloning, protein expression, inhibition kinetics, and function elucidation. J Biol Chem. 2005;280:14341-8 pubmed
    ..These results suggest that serpin-6 plays important roles in the regulation of immune proteinases in the hemolymph. ..
  72. You J, Nguyen A, Albers C, Lin F, Holcombe R. Wnt pathway-related gene expression in inflammatory bowel disease. Dig Dis Sci. 2008;53:1013-9 pubmed
    ..The role and complex regulation of Sox17 and iNOS in IBD warrant further investigation. ..
  73. Surdej P, Jacobs Lorena M. Developmental regulation of bicoid mRNA stability is mediated by the first 43 nucleotides of the 3' untranslated region. Mol Cell Biol. 1998;18:2892-900 pubmed
    ..quot; Similar mechanisms may regulate a class of developmentally important maternal genes whose mRNA has a temporal profile similar to that of bicoid. ..
  74. Majeski E, Harley R, Bellum S, London S, London L. Differential role for T cells in the development of fibrotic lesions associated with reovirus 1/L-induced bronchiolitis obliterans organizing pneumonia versus Acute Respiratory Distress Syndrome. Am J Respir Cell Mol Biol. 2003;28:208-17 pubmed
    ..Furthermore, we suggest that interferon-gamma plays a key role in the fibrotic process and that elevated levels of interferon-gamma are associated with a continuum from least to more severe fibrosis...
  75. Chang S, Garcia J, Melendez J, Kilberg M, Agarwal A. Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain. Biochem J. 2003;371:877-85 pubmed
    ..These results demonstrate that activation of the HO-1 gene by glucose deprivation is mediated by a 'glucose metabolic response' pathway via generation of ROS and that the pathway requires a functional electron-transport chain. ..
  76. Lingohr M, Briaud I, Dickson L, McCuaig J, Alarcon C, Wicksteed B, et al. Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells. J Biol Chem. 2006;281:15884-92 pubmed
  77. Hamilton J, Bement W, Sinclair P, Sinclair J, Alcedo J, Wetterhahn K. Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription. Arch Biochem Biophys. 1991;289:387-92 pubmed
  78. Park S, Lord E. Expression studies of SCA in lily and confirmation of its role in pollen tube adhesion. Plant Mol Biol. 2003;51:183-9 pubmed
    ..For further proof of its role in pollen tube adhesion the activity of Escherichia coli-expressed protein has been studied in an in vitro adhesion assay system. ..
  79. Kakar S, Winters S, Zacharias W, Miller D, Flynn S. Identification of distinct gene expression profiles associated with treatment of LbetaT2 cells with gonadotropin-releasing hormone agonist using microarray analysis. Gene. 2003;308:67-77 pubmed
  80. Cho J, Chen L, Kim M, Chow R, Hille B, Koh D. Characteristics and functions of {alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors expressed in mouse pancreatic {alpha}-cells. Endocrinology. 2010;151:1541-50 pubmed publisher
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