Experts and Doctors on messenger rna in Sweden


Locale: Sweden
Topic: messenger rna

Top Publications

  1. Simons J, Hellman U, Pettersson R. Uukuniemi virus S RNA segment: ambisense coding strategy, packaging of complementary strands into virions, and homology to members of the genus Phlebovirus. J Virol. 1990;64:247-55 pubmed
    ..These results indicate that the uukuviruses and phleboviruses are evolutionarily related and suggest that the two genera could be merged into a single genus within the Bunyaviridae family...
  2. Bhalerao R, Lind L, Gustafsson P. Cloning of the cpcE and cpcF genes from Synechococcus sp. PCC 6301 and their inactivation in Synechococcus sp. PCC 7942. Plant Mol Biol. 1994;26:313-26 pubmed
  3. Petersen U, Bjorklund G, Ip Y, Engstrom Y. The dorsal-related immunity factor, Dif, is a sequence-specific trans-activator of Drosophila Cecropin gene expression. EMBO J. 1995;14:3146-58 pubmed
    ..This study establishes that Dif is a sequence-specific transcription factor and is probably a key activator of the immune response in Drosophila. ..
  4. Johansson M, Nordlund S. Transcription of the glnB and glnA genes in the photosynthetic bacterium Rhodospirillum rubrum. Microbiology. 1996;142 ( Pt 5):1265-72 pubmed
    ..The total level of the two transcripts was much higher in nitrogen-fixing cells than in ammonia-grown cells. ..
  5. Kuusela P, Jacobsson A, Klingenspor M, Rehnmark S, Heldmaier G, Cannon B, et al. Contrasting adrenergic effects on lipoprotein lipase gene expression in the brown adipose tissue of intact mice and in cultured brown adipocytes from mice. Biochim Biophys Acta. 1997;1345:327-37 pubmed
  6. Holmberg K, Shi T, Albers K, Davis B, Hokfelt T. Effect of peripheral nerve lesion and lumbar sympathectomy on peptide regulation in dorsal root ganglia in the NGF-overexpressing mouse. Exp Neurol. 2001;167:290-303 pubmed
    ..Finally, expression of NPY in sympathetic ganglia is differently regulated in NGFOE compared to wild-type mice. ..
  7. Roxström Lindquist K, Faye I. The Drosophila gene Yippee reveals a novel family of putative zinc binding proteins highly conserved among eukaryotes. Insect Mol Biol. 2001;10:77-86 pubmed
    ..Although the Hemolin-Yippee interaction remains to be further elucidated, the high degree of Yippee sequence conservation between a wide range of species suggests that this protein is of general importance in eukaryotes. ..
  8. Reissmann E, Jornvall H, Blokzijl A, Andersson O, Chang C, Minchiotti G, et al. The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development. Genes Dev. 2001;15:2010-22 pubmed
    ..Therefore, our results indicate that both ALK4 and ALK7 can mediate signal transduction by Nodal proteins, although ALK7 appears to be a receptor more specifically dedicated to Nodal signaling. ..
  9. Magnusson C, Högklint L, Libelius R, Tagerud S. Expression of mRNA for plasminogen activators and protease nexin-1 in innervated and denervated mouse skeletal muscle. J Neurosci Res. 2001;66:457-63 pubmed
    ..No difference was observed between PN-1 expression in perisynaptic and extrasynaptic regions. The effect of denervation on PA enzymatic activity in skeletal muscle is therefore likely to be mediated at some post-transcriptional level. ..

More Information

Publications223 found, 100 shown here

  1. Zhao J, Jin S, Bjorkroth B, Wieslander L, Daneholt B. The mRNA export factor Dbp5 is associated with Balbiani ring mRNP from gene to cytoplasm. EMBO J. 2002;21:1177-87 pubmed
    ..Finally, the addition of the export factor Dbp5 to the growing transcript highlights the importance of the co-transcriptional loading process in determining the fate of mRNA. ..
  2. Lindén D, Lindberg K, Oscarsson J, Claesson C, Asp L, Li L, et al. Influence of peroxisome proliferator-activated receptor alpha agonists on the intracellular turnover and secretion of apolipoprotein (Apo) B-100 and ApoB-48. J Biol Chem. 2002;277:23044-53 pubmed
    ..These findings suggest that PPAR alpha and LFABP could interact to amplify the effect of endogenous PPAR alpha agonists on the assembly of VLDL. ..
  3. Savenkov E, Valkonen J. Silencing of a viral RNA silencing suppressor in transgenic plants. J Gen Virol. 2002;83:2325-35 pubmed
    ..Methylation of the HC(pro) transgene followed recovery. These data show that the transgene mRNA for a silencing suppressor can be silenced by a presumably 'strong' silencing inducer (replicating homologous virus). ..
  4. Ransjö M, Sahli J, Lie A. Expression of connexin 43 mRNA in microisolated murine osteoclasts and regulation of bone resorption in vitro by gap junction inhibitors. Biochem Biophys Res Commun. 2003;303:1179-85 pubmed
    ..In conclusion, our data indicate a functional role for gap junction communication in bone resorption. ..
  5. Somogyi E, Petersson U, Hultenby K, Wendel M. Calreticulin--an endoplasmic reticulum protein with calcium-binding activity is also found in the extracellular matrix. Matrix Biol. 2003;22:179-91 pubmed
    ..We now present the first convincing evidence that CRT is found in extracellular matrix where it may play an important role in mineralization...
  6. Hutchinson D, Bengtsson T. alpha1A-adrenoceptors activate glucose uptake in L6 muscle cells through a phospholipase C-, phosphatidylinositol-3 kinase-, and atypical protein kinase C-dependent pathway. Endocrinology. 2005;146:901-12 pubmed
    ..This study demonstrates that alpha1-adrenoceptors mediate increases in glucose uptake in L6 muscle cells. This effect appears to be related to activation of phospholipase C, phosphatidylinositol-3 kinase, p38 kinase, and PKC. ..
  7. Samolov B, Steen B, Seregard S, van der Ploeg I, Montan P, Kvanta A. Delayed inflammation-associated corneal neovascularization in MMP-2-deficient mice. Exp Eye Res. 2005;80:159-66 pubmed
    ..These results implicate a role for MMP-2 in experimental inflammation-associated corneal neovascularization. ..
  8. Cao Y, He L, Xu C, Luo G, Edvinsson L. Enhanced transcription of contractile 5-hydroxytryptamine 2A receptors via extracellular signal-regulated kinase 1/2 after organ culture of rat mesenteric artery. Basic Clin Pharmacol Toxicol. 2005;96:282-8 pubmed
    ..These data reveal a role of ERK1/2 in up-regulation of 5-HT2A receptors and suggest a possibility to inhibit the enhanced responses to 5-HT by inhibition of the ERK1/2 pathway. ..
  9. Manni L, Holmang A, Lundeberg T, Aloe L, Stener Victorin E. Ovarian expression of alpha (1)- and beta (2)-adrenoceptors and p75 neurotrophin receptors in rats with steroid-induced polycystic ovaries. Auton Neurosci. 2005;118:79-87 pubmed
    ..Overall, our findings suggest that therapeutical approaches aimed at down-regulating the sympathetic tone to the ovary could be useful in the prevention and clinical treatment of PCOS. ..
  10. Mousavi M, Nordberg A. Expression of the alpha7, alpha4 and alpha3 nicotinic receptor subtype in the brain and adrenal medulla of transgenic mice carrying genes coding for human AChE and beta-amyloid. Int J Dev Neurosci. 2006;24:269-73 pubmed
    ..The findings may have implications for a better understanding the underlying mechanism for AD-related pathogenesis...
  11. Andin J, Hallbeck M, Mohammed A, Marcusson J. Influence of environmental enrichment on steady-state mRNA levels for EAAC1, AMPA1 and NMDA2A receptor subunits in rat hippocampus. Brain Res. 2007;1174:18-27 pubmed
  12. Hultman K, Blomstrand F, Nilsson M, Wilhelmsson U, Malmgren K, Pekny M, et al. Expression of plasminogen activator inhibitor-1 and protease nexin-1 in human astrocytes: Response to injury-related factors. J Neurosci Res. 2010;88:2441-9 pubmed publisher
    ..We show here that human astrocytes express PAI-1 and PN-1 and demonstrate that this astrocytic expression is regulated in a dynamic manner by injury-related factors. ..
  13. Ren J, Albinsson S, Hellstrand P. Distinct effects of voltage- and store-dependent calcium influx on stretch-induced differentiation and growth in vascular smooth muscle. J Biol Chem. 2010;285:31829-39 pubmed publisher
    ..Compartmentation of Ca(2+) entry pathways appears as one mechanism whereby extracellular and membrane signals influence smooth muscle phenotype regulation, with MEF2 as a focal point. ..
  14. Goransson M, Sonden B, Nilsson P, Dagberg B, Forsman K, Emanuelsson K, et al. Transcriptional silencing and thermoregulation of gene expression in Escherichia coli. Nature. 1990;344:682-5 pubmed
    ..We have now identified and characterized a new regulatory locus (drdX) and show that a histone-like bacterial protein has an important role in this novel example of thermoregulation of transcription. ..
  15. Oldberg A, Franzen A, Heinegard D. The primary structure of a cell-binding bone sialoprotein. J Biol Chem. 1988;263:19430-2 pubmed
    ..BSP contains an Arg-Gly-Asp sequence, which presumably is responsible for its cell binding properties (Oldberg, A., Franzén, A., Heinegård, D., Pierschbacher, M., and Ruoslahti, E. (1988) J. Biol. Chem. 263, 19433-19436). ..
  16. Hu G, Ronne H. Overexpression of yeast PAM1 gene permits survival without protein phosphatase 2A and induces a filamentous phenotype. J Biol Chem. 1994;269:3429-35 pubmed
    ..The PAM1 gene encodes a hydrophilic 93-kDa protein that contains two coiled coil motifs and has a highly basic C-terminal tail. High level overexpression of PAM1 inhibits growth and induces a filamentous phenotype. ..
  17. Diczfalusy U, Eggertsen G, Alexson S. Clofibrate treatment increases stearoyl-CoA desaturase mRNA level and enzyme activity in mouse liver. Biochim Biophys Acta. 1995;1259:313-6 pubmed
    ..The highest expression of both SCD1 and SCD2 was found in brown adipose tissue, which was slightly down-regulated by feeding a fat-free diet. ..
  18. Olofsson B, Pajusola K, von Euler G, Chilov D, Alitalo K, Eriksson U. Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform. J Biol Chem. 1996;271:19310-7 pubmed
    ..The entirely different COOH-terminal domains in the two isoforms of vascular endothelial growth factor B imply that some functional properties of the two proteins are distinct. ..
  19. Fredrikson G, Gullstrand B, Westberg J, Sjoholm A, Uhlen M, Truedsson L. Expression of properdin in complete and incomplete deficiency: normal in vitro synthesis by monocytes in two cases with properdin deficiency type II due to distinct mutations. J Clin Immunol. 1998;18:272-82 pubmed
    ..Analysis of properdin expression by monocytes in a female carrier in the family with properdin deficiency type I provided direct evidence of lyonization at the cellular level. ..
  20. Frohm Nilsson M, Sandstedt B, Sørensen O, Weber G, Borregaard N, Ståhle Bäckdahl M. The human cationic antimicrobial protein (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and colocalizes with interleukin-6. Infect Immun. 1999;67:2561-6 pubmed
    ..Furthermore, colocalization with interleukin-6 indicates a potential local mechanism for the upregulation of hCAP18 at the epithelial surfaces. ..
  21. Klasson H, Fink G, Ljungdahl P. Ssy1p and Ptr3p are plasma membrane components of a yeast system that senses extracellular amino acids. Mol Cell Biol. 1999;19:5405-16 pubmed
    ..These findings suggest that Ssy1p and Ptr3p function in the PM as components of a sensor of extracellular amino acids. ..
  22. Matthias A, Jacobsson A, Cannon B, Nedergaard J. The bioenergetics of brown fat mitochondria from UCP1-ablated mice. Ucp1 is not involved in fatty acid-induced de-energization ("uncoupling"). J Biol Chem. 1999;274:28150-60 pubmed
    ..Thus, the mere observation of a high level of Ucp2 or Ucp3 mRNA in a tissue cannot be taken as an indication that mitochondria isolated from that tissue will display innate de-energization or thermogenesis. ..
  23. Percipalle P, Jonsson A, Nashchekin D, Karlsson C, Bergman T, Guialis A, et al. Nuclear actin is associated with a specific subset of hnRNP A/B-type proteins. Nucleic Acids Res. 2002;30:1725-34 pubmed
    ..We propose that actin associated with DBP40, and perhaps with additional hnRNP A/B-type proteins, is transferred from nucleus to cytoplasm bound to mRNA. ..
  24. Juremalm M, Olsson N, Nilsson G. Selective CCL5/RANTES-induced mast cell migration through interactions with chemokine receptors CCR1 and CCR4. Biochem Biophys Res Commun. 2002;297:480-5 pubmed
    ..These results demonstrate that both CCR1 and CCR4 are functional receptors on human mast cells with capacity to mediate migration towards CCL5. ..
  25. Nygard M, Wahlström G, Gustafsson M, Tokumoto Y, Bondesson M. Hormone-dependent repression of the E2F-1 gene by thyroid hormone receptors. Mol Endocrinol. 2003;17:79-92 pubmed
    ..We suggest that this is an initial and crucial step in thyroid hormone-induced differentiation of precursor cells. ..
  26. Phillipson M, Henriksnäs J, Holstad M, Sandler S, Holm L. Inducible nitric oxide synthase is involved in acid-induced gastric hyperemia in rats and mice. Am J Physiol Gastrointest Liver Physiol. 2003;285:G154-62 pubmed
    ..The results suggest that iNOS is constitutively expressed in the gastric mucosa and is involved in acid-induced hyperemia, suggesting a novel role for iNOS in gastric mucosal protection. ..
  27. Zhang Y, Adner M, Cardell L. Glucocorticoids suppress transcriptional up-regulation of bradykinin receptors in a murine in vitro model of chronic airway inflammation. Clin Exp Allergy. 2005;35:531-8 pubmed
  28. Ivanova N, Pavlov M, Ehrenberg M. tmRNA-induced release of messenger RNA from stalled ribosomes. J Mol Biol. 2005;350:897-905 pubmed
    ..The reduced rate of release in the former case was due to a persisting SD-anti SD interaction between mRNA and the ribosome. ..
  29. Nordström K. Plasmid R1--replication and its control. Plasmid. 2006;55:1-26 pubmed
    ..The clusters are plasmid-specific and presumably based on sequence homology. ..
  30. Sourial Bassillious N, Eklöf A, Scott L, Aperia A, Zelenin S. Effect of TNF-alpha on CD3-zeta and MHC-I in postnatal rat hippocampus. Pediatr Res. 2006;60:377-81 pubmed
    ..These results may offer a molecular explanation to the adverse effects of increased circulating levels of cytokines on brain in neonatal hypoxia. ..
  31. Wootz H, Weber E, Korhonen L, Lindholm D. Altered distribution and levels of cathepsinD and cystatins in amyotrophic lateral sclerosis transgenic mice: possible roles in motor neuron survival. Neuroscience. 2006;143:419-30 pubmed
    ..The observed changes in the levels and distributions of cathepsinD and cystatinB and-C indicate a role of these proteins in the degeneration of motor neurons in ALS. ..
  32. Mark L, Spiller O, Okroj M, Chanas S, Aitken J, Wong S, et al. Molecular characterization of the rhesus rhadinovirus (RRV) ORF4 gene and the RRV complement control protein it encodes. J Virol. 2007;81:4166-76 pubmed
    ..These data provide the foundation for studies into the biological significance of gammaherpesvirus complement regulatory proteins in a tractable, non-human primate model...
  33. Hosseinpour F, Ellfolk M, Norlin M, Wikvall K. Phenobarbital suppresses vitamin D3 25-hydroxylase expression: a potential new mechanism for drug-induced osteomalacia. Biochem Biophys Res Commun. 2007;357:603-7 pubmed
    ..A downregulation of 25-hydroxylation by phenobarbital may explain, at least in part, the increased risk of osteomalacia, bone loss, and fractures in long-term phenobarbital therapy...
  34. Ahlzén M, Johansson L, Cervin C, Tornqvist H, Groop L, Ridderstrale M. Expression of the transcription factor 7-like 2 gene (TCF7L2) in human adipocytes is down regulated by insulin. Biochem Biophys Res Commun. 2008;370:49-52 pubmed publisher
    ..In conclusion, TCF7L2 mRNA levels in adipocytes are decreased by insulin and seem to increase in insulin resistant subjects and in HapA carriers. ..
  35. Sukjumlong S, Persson E, Dalin A, Janson V, Sahlin L. Messenger RNA levels of estrogen receptors alpha and beta and progesterone receptors in the cyclic and inseminated/early pregnant sow uterus. Anim Reprod Sci. 2009;112:215-28 pubmed publisher
    ..g. insemination and/or the presence of embryos, influence the expression of these steroid receptor mRNAs in the sow uterus. ..
  36. Månsson Broberg A, Siddiqui A, Genander M, Grinnemo K, Hao X, Andersson A, et al. Modulation of ephrinB2 leads to increased angiogenesis in ischemic myocardium and endothelial cell proliferation. Biochem Biophys Res Commun. 2008;373:355-9 pubmed publisher
    ..These results implicate that EphB4/ephrinB2 is an important signaling pathway in ischemic heart disease and its modulation may induce therapeutic angiogenesis. ..
  37. Hansson S, Bottalico B, Noskova V, Casslén B. Monoamine transporters in human endometrium and decidua. Hum Reprod Update. 2009;15:249-60 pubmed publisher
    ..New knowledge about monoamine metabolism in the endometrium during menstruation and pregnancy will increase understanding of infertility problems and may offer new pharmacological approaches to optimize assisted reproduction. ..
  38. Yenamandra S, Lundin A, Arulampalam V, Yurchenko M, Pettersson S, Klein G, et al. Expression profile of nuclear receptors upon Epstein -- Barr virus induced B cell transformation. Exp Oncol. 2009;31:92-6 pubmed
    ..Further analysis on a possible role of each nuclear receptor in EBV induced cell transformation should be performed. ..
  39. Panayiotou C, Solaroli N, Johansson M, Karlsson A. Evidence of an intact N-terminal translocation sequence of human mitochondrial adenylate kinase 4. Int J Biochem Cell Biol. 2010;42:62-9 pubmed publisher
    ..Site directed mutagenesis of amino acids Lys 4 and Arg 7 showed that these two residues were essential for mitochondrial import. ..
  40. Westermark M, Oscarsson J, Mizunoe Y, Urbonaviciene J, Uhlin B. Silencing and activation of ClyA cytotoxin expression in Escherichia coli. J Bacteriol. 2000;182:6347-57 pubmed
    ..We suggest that it represents a regulatory region which is particularly susceptible to H-NS silencing, and its features are discussed in relation to regulation of other silenced operons. ..
  41. Correa P, Akerstrom G, Westin G. Exclusive underexpression of vitamin D receptor exon 1f transcripts in tumors of primary hyperparathyroidism. Eur J Endocrinol. 2002;147:671-5 pubmed
  42. Diez M, Schweinhardt P, Petersson S, Wang F, Lavebratt C, Schalling M, et al. MRI and in situ hybridization reveal early disturbances in brain size and gene expression in the megencephalic (mceph/mceph) mouse. Eur J Neurosci. 2003;18:3218-30 pubmed
    ..These results provide an objective description of the size changes in different brain regions of the mceph/mceph mouse, and suggest that certain molecules could be involved in the early processes underlying these changes. ..
  43. Ståhlberg A, Bengtsson M. Single-cell gene expression profiling using reverse transcription quantitative real-time PCR. Methods. 2010;50:282-8 pubmed publisher
    ..Single-cell gene expression profiling has the potential to become common practice in many laboratories and a powerful research tool for deeper understanding of molecular mechanisms. ..
  44. Westin U, Fryksmark U, Polling A, Ohlsson K. Localisation of secretory leucocyte proteinase inhibitor mRNA in nasal mucosa. Acta Otolaryngol. 1994;114:199-202 pubmed
    ..This, together with the high concentration of SLPI in nasal secretions, confirms the hypothesis of a local production of SLPI in the mucous membranes. ..
  45. Leonardsson G, Peng X, Liu K, Nordstrom L, Carmeliet P, Mulligan R, et al. Ovulation efficiency is reduced in mice that lack plasminogen activator gene function: functional redundancy among physiological plasminogen activators. Proc Natl Acad Sci U S A. 1995;92:12446-50 pubmed
  46. Makino Y, Kanopka A, Wilson W, Tanaka H, Poellinger L. Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus. J Biol Chem. 2002;277:32405-8 pubmed
    ..Importantly, this mechanism may establish negative feedback loop regulation of adaptive responses to hypoxia/ischemia in these tissues. ..
  47. Frick F, Lindén D, Améen C, Edén S, Mode A, Oscarsson J. Interaction between growth hormone and insulin in the regulation of lipoprotein metabolism in the rat. Am J Physiol Endocrinol Metab. 2002;283:E1023-31 pubmed
    ..Insulin does not mediate the effects of GH but inhibits the stimulatory effect of GH on hepatic SREBP-1c expression and triglyceride secretion rate. ..
  48. Egecioglu E, Andersson I, Bollano E, Palsdottir V, Gabrielsson B, Kopchick J, et al. Growth hormone receptor deficiency in mice results in reduced systolic blood pressure and plasma renin, increased aortic eNOS expression, and altered cardiovascular structure and function. Am J Physiol Endocrinol Metab. 2007;292:E1418-25 pubmed
    ..These data suggest an important role for an intact GH/IGF-I axis in the maintenance of a normal cardiovascular system. ..
  49. Jennische E, Matejka G. IGF-I binding and IGF-I expression in regenerating muscle of normal and hypophysectomized rats. Acta Physiol Scand. 1992;146:79-86 pubmed
    ..It is concluded that locally produced IGF-I is the most likely ligand for IGF-I receptors during muscle regeneration. ..
  50. Rydberg E, Salomonsson L, Hulten L, Norén K, Bondjers G, Wiklund O, et al. Hypoxia increases 25-hydroxycholesterol-induced interleukin-8 protein secretion in human macrophages. Atherosclerosis. 2003;170:245-52 pubmed
    ..Thus, hypoxia in atherosclerotic plaques may increase the secretion of IL-8 from oxysterol-containing foam cells, which subsequently may accelerate the progression of atherosclerosis. ..
  51. Jin H, Zhao Q, Gonzalez de Valdivia E, Ardell D, Stenström M, Isaksson L. Influences on gene expression in vivo by a Shine-Dalgarno sequence. Mol Microbiol. 2006;60:480-92 pubmed
    ..Analysis of the E. coli K12 genome suggests that the SD+ or SD-like sequences are systematically avoided in the early coding region suggesting an evolutionary significance. ..
  52. Mathe A, Husum H, El Khoury A, Jiménez Vasquez P, Gruber S, Wortwein G, et al. Search for biological correlates of depression and mechanisms of action of antidepressant treatment modalities. Do neuropeptides play a role?. Physiol Behav. 2007;92:226-31 pubmed
    ..Consequently, if these data are confirmed, the ethical and medical question that will be asked is whether it is permissible and advisable to consider prophylactically treating persons at risk. ..
  53. Wang H, Stjernholm Y, Ekman G, Eriksson H, Sahlin L. Different regulation of oestrogen receptors alpha and beta in the human cervix at term pregnancy. Mol Hum Reprod. 2001;7:293-300 pubmed
    ..Furthermore, oestrogen may mediate some effects on cervical ripening via ERbeta present in the invading neutrophils. Further studies are needed to elucidate this finding. ..
  54. McGuire J, Poellinger L, Wikstrom A, Gustafsson J. Cloning and regulation by glucocorticoid receptor ligands of a rat hsp90. J Steroid Biochem Mol Biol. 1992;42:813-22 pubmed
    ..In this system, a subtle but reproducible approx. 2-fold decrease in hsp90 mRNA levels is observed after 48 h treatment with dexamethasone. ..
  55. Jansson A, Emterling A, Arbman G, Sun X. Noxa in colorectal cancer: a study on DNA, mRNA and protein expression. Oncogene. 2003;22:4675-8 pubmed
    ..The protein level in most of the cases investigated was correlated with the mRNA level. We did not find any mutations in the Noxa gene. Thus, we suggest that Noxa may not be of importance in the development of colorectal cancer. ..
  56. Birgner C, Kindlundh Högberg A, Oreland L, Alsiö J, Lindblom J, Schioth H, et al. Reduced activity of monoamine oxidase in the rat brain following repeated nandrolone decanoate administration. Brain Res. 2008;1219:103-10 pubmed publisher
  57. Zaphiropoulos P. cDNA cloning and regulation of a novel rat cytochrome P450 of the 2C gene subfamily (P450IIC24). Biochem Biophys Res Commun. 1991;180:645-51 pubmed
    ..Interestingly, although livers of mature rats of both sexes have comparable amounts of P4502C24 mRNA, a dramatic sex difference is seen in the kidney where only males express detectable levels of this mRNA. ..
  58. Cetkovic Cvrlje M, Eizirik D. TNF-alpha and IFN-gamma potentiate the deleterious effects of IL-1 beta on mouse pancreatic islets mainly via generation of nitric oxide. Cytokine. 1994;6:399-406 pubmed
    ..Most of the deleterious effects of the cytokines of mouse islets are prevented by blocking NO production, suggesting that NO is the main mediator of cytokine-induced beta-cell damage.(ABSTRACT TRUNCATED AT 250 WORDS) ..
  59. Soderman E, Mattsson J, Svenson M, Borkird C, Engstrom P. Expression patterns of novel genes encoding homeodomain leucine-zipper proteins in Arabidopsis thaliana. Plant Mol Biol. 1994;26:145-54 pubmed
    ..The Athb proteins thus constitute a new and well defined class of homeodomain proteins, apparently unique to plants. ..
  60. Andersson A, Svensson A, Rolny C, Andersson G, Larsson E. Expression of human endogenous retrovirus ERV3 (HERV-R) mRNA in normal and neoplastic tissues. Int J Oncol. 1998;12:309-13 pubmed
    ..This tissue-tropism should be seen in relation to the high expression previously found in syncytiotrophoblasts in placenta and sebaceous glands of the skin, suggesting profound influences by steroid hormonal regulation. ..
  61. Yu W, Guan Z, Nordberg A. Postnatal upregulation of alpha4 and alpha3 nicotinic receptor subunits in the brain of alpha7 nicotinic receptor-deficient mice. Neuroscience. 2007;146:1618-28 pubmed
    ..These data suggest that increased levels of alpha4, alpha3-containing nAChRs, co-assembled with the alpha5 nAChR subunit, may contribute to the normal brain development of alpha7 -/- and alpha7 +/- mice. ..
  62. Sun Y, Wang Y, Zhao J, Gu M, Giscombe R, Lefvert A, et al. B7-H3 and B7-H4 expression in non-small-cell lung cancer. Lung Cancer. 2006;53:143-51 pubmed
    ..These observations suggest the contribution of B7-H3 and B7-H4 to immune dysfunction and tumor progression in NSCLC patients. B7-H3 and B7-H4 may be an important target for diagnosis and/or therapy of NSCLC. ..
  63. Lundholm L, Putnik M, Otsuki M, Andersson S, Ohlsson C, Gustafsson J, et al. Effects of estrogen on gene expression profiles in mouse hypothalamus and white adipose tissue: target genes include glutathione peroxidase 3 and cell death-inducing DNA fragmentation factor, alpha-subunit-like effector A. J Endocrinol. 2008;196:547-57 pubmed publisher
    ..We conclude that estrogen has large effects on gene expression in white adipose tissue and hypothesize that GPX3 and CIDEA could be important mediators of the effects of estrogen on fat mass. ..
  64. Krajisnik T, Björklund P, Marsell R, Ljunggren O, Akerstrom G, Jonsson K, et al. Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells. J Endocrinol. 2007;195:125-31 pubmed
    ..Our data suggest that FGF23 may be a physiologically relevant regulator of PTH. This defines a novel function of FGF23 in addition to the previously established roles in controlling vitamin D and Pi metabolism. ..
  65. Belikov S, Holmqvist P, Astrand C, Wrange O. Nuclear factor 1 and octamer transcription factor 1 binding preset the chromatin structure of the mouse mammary tumor virus promoter for hormone induction. J Biol Chem. 2004;279:49857-67 pubmed
    ..We propose that this state of NF1 and Oct1-induced chromatin presetting mimics the early step(s) of chromatin remodeling involved in tissue-specific gene expression...
  66. Carlsson E, Johansson L, Strom K, Hoffstedt J, Groop L, Holm C, et al. The hormone-sensitive lipase C-60G promoter polymorphism is associated with increased waist circumference in normal-weight subjects. Int J Obes (Lond). 2006;30:1442-8 pubmed
    ..HSL mRNA levels were significantly higher in subcutaneous compared to visceral fat from obese subjects. The HSL C-60G polymorphism is associated with increased waist circumference in non-obese subjects. ..
  67. Uv A, Roth P, Xylourgidis N, Wickberg A, Cantera R, Samakovlis C. members only encodes a Drosophila nucleoporin required for rel protein import and immune response activation. Genes Dev. 2000;14:1945-57 pubmed
    ..Our results demonstrate that distinct nuclear import events require different nucleoporins in vivo and suggest a regulatory role for mbo in signal transduction. ..
  68. Selmer M, Su X. Crystal structure of an mRNA-binding fragment of Moorella thermoacetica elongation factor SelB. EMBO J. 2002;21:4145-53 pubmed
    ..Steric requirements indicate that a conformational change may occur upon ribosome interaction. Structural observations and data in the literature suggest that this change happens upon mRNA binding...
  69. Tehranchi R, Invernizzi R, Grandien A, Zhivotovsky B, Fadeel B, Forsblom A, et al. Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes. Blood. 2005;106:247-53 pubmed
    ..In conclusion, aberrant MtF expression in RARS erythroblasts occurs at a very early stage of erythroid differentiation and is paralleled by an up-regulation of genes involved in this process. ..
  70. Hamasaka Y, Rieger D, Parmentier M, Grau Y, Helfrich Forster C, Nassel D. Glutamate and its metabotropic receptor in Drosophila clock neuron circuits. J Comp Neurol. 2007;505:32-45 pubmed
    ..Our results suggest that a glutamate signal from some of the DNs modulates the rhythmic behavior pattern via DmGluRA on the LN(v)s in Drosophila. ..
  71. Joste V, Goitom Z, Nelson B. Thyroid hormone regulation of nuclear-encoded mitochondrial inner membrane polypeptides of the liver. Eur J Biochem. 1989;184:255-60 pubmed
    ..The possible significance of this response for the regulation of mitochondrial synthesis and assembly is discussed. ..
  72. Abrink M, Aveskogh M, Hellman L. Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937. DNA Cell Biol. 1995;14:125-36 pubmed
    ..In addition, several novel KRAB-containing zinc finger genes and a novel conserved sequence element were identified. ..
  73. Hu G, Ronne H. Yeast BTF3 protein is encoded by duplicated genes and inhibits the expression of some genes in vivo. Nucleic Acids Res. 1994;22:2740-3 pubmed
    ..We conclude that Btt1p and Egd1p have redundant functions in vivo, and that they exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II. ..
  74. Correa P, Akerstrom G, Westin G. Underexpression of Gcm2, a master regulatory gene of parathyroid gland development, in adenomas of primary hyperparathyroidism. Clin Endocrinol (Oxf). 2002;57:501-5 pubmed
    ..We speculate that a proper expression level of the Gcm2 transcription factor could be important for maintaining a fully differentiated state of the parathyroid cell. ..
  75. Wahab Wahlgren A, Martinelle N, Holst M, Jahnukainen K, Parvinen M, Soder O. EGF stimulates rat spermatogonial DNA synthesis in seminiferous tubule segments in vitro. Mol Cell Endocrinol. 2003;201:39-46 pubmed
    ..We suggest that EGF-GFs is involved in the paracrine control of spermatogenesis in vivo. ..
  76. Thurfjell N, Coates P, Uusitalo T, Mahani D, Dabelsteen E, Dahlqvist A, et al. Complex p63 mRNA isoform expression patterns in squamous cell carcinoma of the head and neck. Int J Oncol. 2004;25:27-35 pubmed
    ..The complexity of these p63 expression patterns seen in primary SCCHN indicates that p63 has multifaceted roles in tumour biology. ..
  77. Granström B, Xu C, Nilsson E, Bengtsson U, Edvinsson L. Up-regulation of endothelin receptor function and mRNA expression in airway smooth muscle cells following Sephadex-induced airway inflammation. Basic Clin Pharmacol Toxicol. 2004;95:43-8 pubmed
  78. Norman H, Zackrisson H, Hedström Y, Andersson P, Nordquist J, Eriksson L, et al. Myofibrillar protein and gene expression in acute quadriplegic myopathy. J Neurol Sci. 2009;285:28-38 pubmed publisher
  79. Bondeson J, Sundler R. Auranofin inhibits the induction of interleukin 1 beta and tumor necrosis factor alpha mRNA in macrophages. Biochem Pharmacol. 1995;50:1753-9 pubmed
    ..The fact that AF inhibited the induction of mRNA for both these proinflammatory cytokines, irrespective of which stimulus was used, may indicate that it affects some common signal transduction step vital to their induction. ..
  80. Forsberg L, Zablewska B, Piehl F, Weber G, Lagercrantz S, Gaudray P, et al. Differential expression of multiple alternative spliceforms of the Men1 tumor suppressor gene in mouse. Int J Mol Med. 2001;8:681-9 pubmed
    ..Notably, no menin expression was detectable in the extracts from epididymis where the maturation of sperms is almost completed, suggesting that menin plays a crucial role during spermatogenesis. ..
  81. Grahn A, Barkhordar G, Larson G. Cloning and sequencing of nineteen transcript isoforms of the human alpha2,3-sialyltransferase gene, ST3Gal III; its genomic organisation and expression in human tissues. Glycoconj J. 2002;19:197-210 pubmed
    ..Neural and muscular tissues showed the most complex patterns and were distinctly different from all other tissues examined. ..
  82. Kotokorpi P, Gardmo C, Nyström C, Mode A. Activation of the glucocorticoid receptor or liver X receptors interferes with growth hormone-induced akr1b7 gene expression in rat hepatocytes. Endocrinology. 2004;145:5704-13 pubmed
  83. Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee J, Lötvall J. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9:654-9 pubmed
    ..In summary, we show that exosomes contain both mRNA and microRNA, which can be delivered to another cell, and can be functional in this new location. We propose that this RNA is called "exosomal shuttle RNA" (esRNA). ..
  84. Liedman R, Hansson S, Howe D, Igidbashian S, Russell R, Akerlund M. Endometrial expression of vasopressin, oxytocin and their receptors in patients with primary dysmenorrhoea and healthy volunteers at ovulation. Eur J Obstet Gynecol Reprod Biol. 2008;137:189-92 pubmed
    ..A lower oxytocin receptor gene expression at mid-cycle could be involved in the aetiology of primary dysmenorrhoea. However, the importance of a paracrine effect of oxytocin and its receptor at ovulation warrants further investigation. ..
  85. Kylsten P, Samakovlis C, Hultmark D. The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection. EMBO J. 1990;9:217-24 pubmed
    ..The cecropin genes were also induced when the flies were kept on food with the Drosophila pathogenic bacterium Serratia marcescens Db10 or its non-pathogenic derivative Db1140. ..
  86. Westin S, Sonneveld E, van der Leede B, van der Saag P, Gustafsson J, Mode A. CYP2C7 expression in rat liver and hepatocytes: regulation by retinoids. Mol Cell Endocrinol. 1997;129:169-79 pubmed
    ..We suggest that metabolism of at-RA, possibly by a P450 enzyme, is an important step in the at-RA induction of P4502C7. ..
  87. Lind M, Ekengren S, Melefors O, Soderhall K. Drosophila ferritin mRNA: alternative RNA splicing regulates the presence of the iron-responsive element. FEBS Lett. 1998;436:476-82 pubmed
    ..Our data provides the first molecular evidence that the presence of iron-responsive element in a ferritin mRNA is regulated by alternative RNA splicing. ..
  88. Tivesten A, Barlind A, Caidahl K, Klintland N, Cittadini A, Ohlsson C, et al. Growth hormone-induced blood pressure decrease is associated with increased mRNA levels of the vascular smooth muscle KATP channel. J Endocrinol. 2004;183:195-202 pubmed
    ..Increased expression of the ATP-sensitive potassium channel, recently shown to be crucial in the regulation of vascular tone, constitutes a possible mechanism by which GH governs vascular tone...
  89. Palmblad K, Sundberg E, Diez M, Söderling R, Aveberger A, Andersson U, et al. Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis. Arthritis Res Ther. 2007;9:R35 pubmed
    ..In conclusion, these new findings implicate a role for HMGB1 in both inducing and perpetuating inflammatory events of significant importance in the destructive processes in chronic arthritis. ..
  90. Wahlstedt H, Daniel C, Ensterö M, Ohman M. Large-scale mRNA sequencing determines global regulation of RNA editing during brain development. Genome Res. 2009;19:978-86 pubmed publisher
    ..Furthermore, we show that this regulation of editing activity cannot be explained by an altered expression of the ADAR proteins but, rather, by the presence of a regulatory network that controls the editing activity during development. ..
  91. Oreland S, Pickering C, Gokturk C, Oreland L, Arborelius L, Nylander I. Two repeated maternal separation procedures differentially affect brain 5-hydroxytryptamine transporter and receptors in young and adult male and female rats. Brain Res. 2009;1305 Suppl:S37-49 pubmed publisher
    ..The results suggest that MS15i is less suitable than MS15l to simulate a protective environment in studies of, for instance, ethanol addiction processes. ..
  92. Pinto F, Lindblad P. A guide for in-house design of template-switch-based 5' rapid amplification of cDNA ends systems. Anal Biochem. 2010;397:227-32 pubmed publisher
    ..We show that the resulting system is reliable, time-efficient, and inexpensive. ..