Experts and Doctors on messenger rna in Japan

Summary

Locale: Japan
Topic: messenger rna

Top Publications

  1. Ohta M, Sugita M, Sugiura M. Three types of nuclear genes encoding chloroplast RNA-binding proteins (cp29, cp31 and cp33) are present in Arabidopsis thaliana: presence of cp31 in chloroplasts and its homologue in nuclei/cytoplasms. Plant Mol Biol. 1995;27:529-39 pubmed
    ..FMV3bp lacks a transit-peptide and must be located in the nucleus or the cytoplasm. ..
  2. Takebayashi K, Sasai Y, Sakai Y, Watanabe T, Nakanishi S, Kageyama R. Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements. J Biol Chem. 1994;269:5150-6 pubmed
    ..Furthermore, when the N box sequences are disrupted, this negative regulation is severely impaired. These results raise the possibility that HES-1 gene expression may be negatively autoregulated through the N box sequences. ..
  3. Yoshida A, Koide Y, Uchijima M, Yoshida T. IFN-gamma induces IL-12 mRNA expression by a murine macrophage cell line, J774. Biochem Biophys Res Commun. 1994;198:857-61 pubmed
    ..The IFN-gamma-inducible IL-12 mRNA was blocked by two protein tyrosine kinase (PTK) inhibitors, genistein and herbimycin A, suggesting that PTK is involved in the IFN-gamma-inducible IL-12 mRNA expression. ..
  4. Ito K, Tsutsumi K, Kuzumaki T, Gomez P, Otsu K, Ishikawa K. A novel growth-inducible gene that encodes a protein with a conserved cold-shock domain. Nucleic Acids Res. 1994;22:2036-41 pubmed
    ..Since both treatments are known to inhibit G1 cells to enter S phase, RYB-a gene is thought to be a member of growth-inducible genes. ..
  5. Kato A, Sugiura N, Hagiwara H, Hirose S. Cloning, amino acid sequence and tissue distribution of porcine thimet oligopeptidase. A comparison with soluble angiotensin-binding protein. Eur J Biochem. 1994;221:159-65 pubmed
    ..This assay also revealed tissue-specific alternative splicing of the sABP-encoding message. ..
  6. Suzuki T, Kobayashi K, Nagatsu T. Genomic structure and tissue distribution of the mouse dopamine D4 receptor. Neurosci Lett. 1995;199:69-72 pubmed
    ..We observed several differences in tissue distribution of the D4 mRNA in mice from that reported in other mammalian species. ..
  7. Kimura T, Takemura M, Nomura S, Nobunaga T, Kubota Y, Inoue T, et al. Expression of oxytocin receptor in human pregnant myometrium. Endocrinology. 1996;137:780-5 pubmed
    ..These findings indicated that the expression of OTR changes dynamically at the transcription and protein level during pregnancy and that its expression is heterogeneous in the term myometrium. ..
  8. Sugimoto K, Honda S, Yamamoto T, Ueki T, Monden M, Kaji A, et al. Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin. J Biol Chem. 1996;271:11548-56 pubmed
    ..PB-cadherin may play an important role in morphogenesis and tissue formation in neural and non-neural cells for the development and maintenance of the brain and neuroendocrine organs by regulating cell-cell adhesion. ..
  9. Iwatsuki K, Shinozaki M, Hattori N, Hirasawa K, Itagaki S, Shiota K, et al. Molecular cloning and characterization of a new member of the rat placental prolactin (PRL) family, PRL-like protein D (PLP-D). Endocrinology. 1996;137:3849-55 pubmed
    ..Differentiated Rcho-1 cells also expressed PLP-D mRNA, whereas undifferentiated Rcho-1 cells did not. ..

More Information

Publications308 found, 100 shown here

  1. Baba M, Imai T, Nishimura M, Kakizaki M, Takagi S, Hieshima K, et al. Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARC. J Biol Chem. 1997;272:14893-8 pubmed
    ..Taken together, GPR-CY4 is the specific receptor for LARC expressed selectively on lymphocytes, and LARC is a unique functional ligand for GPR-CY4. We propose GPR-CY4 to be designated as CCR6. ..
  2. Kubo H, Kawano T, Tsubuki S, Kawashima S, Katagiri C, Suzuki A. A major glycoprotein of Xenopus egg vitelline envelope, gp41, is a frog homolog of mammalian ZP3. Dev Growth Differ. 1997;39:405-17 pubmed
    ..A comparison of the N-terminal sequences of gp41 and gp43 strongly suggested that gp41 is generated at least by processing of the N-terminal portion of gp43 with oviductin. ..
  3. Segi E, Sugimoto Y, Yamasaki A, Aze Y, Oida H, Nishimura T, et al. Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice. Biochem Biophys Res Commun. 1998;246:7-12 pubmed
    ..They also indicate that normal function of the EP4 receptor is essential in neonatal adaptation of the circulatory system. ..
  4. Kobayashi K, Kobayashi H, Ueda M, Honda Y. Estrogen receptor expression in bovine and rat retinas. Invest Ophthalmol Vis Sci. 1998;39:2105-10 pubmed
    ..This study provides the first evidence for the presence of estrogen receptor in bovine and rat retinas. Expression of estrogen receptor throughout the retina suggests that estrogen may have important functions in the retina. ..
  5. Kimura H, Fujii H, Suzuki S, Ono T, Arakawa M, Gejyo F. Lipid-binding proteins in rat and human kidney. Kidney Int Suppl. 1999;71:S159-62 pubmed
    ..CRBP and mRNA was detected in RG but not RMC. A variety of lipid-binding proteins are present in rat glomeruli. In human glomeruli, a novel 110-kDa H-FABP-related protein is localized specifically in the capillary wall. ..
  6. Iseki M, Takaki S, Takatsu K. Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins. Biochem Biophys Res Commun. 2000;272:45-54 pubmed
    ..These results suggest that APS is a member of the Lnk family adaptor protein and likely plays a role in signaling in B cells. ..
  7. Tang W, Nakamura Y, Tsujimoto M, Sato M, Wang X, Kurozumi K, et al. Heparanase: a key enzyme in invasion and metastasis of gastric carcinoma. Mod Pathol. 2002;15:593-8 pubmed
    ..It was indicated that patients with heparanase-positive gastric carcinoma would have a greater chance of metastasis with a poor prognosis. ..
  8. Takemoto S, Murakami T, Kusachi S, Iwabu A, Hirohata S, Nakamura K, et al. Increased expression of dermatopontin mRNA in the infarct zone of experimentally induced myocardial infarction in rats: comparison with decorin and type I collagen mRNAs. Basic Res Cardiol. 2002;97:461-8 pubmed
    ..Coexpression of dermatopontin mRNA with decorin and type I collagen mRNAs suggests that dermatopontin plays a role in ECM (fibrillar collagen matrix) reformation in the infarct along with decorin and type I collagen. ..
  9. Xu X, Yamamoto H, Sakon M, Yasui M, Ngan C, Fukunaga H, et al. Overexpression of CDC25A phosphatase is associated with hypergrowth activity and poor prognosis of human hepatocellular carcinomas. Clin Cancer Res. 2003;9:1764-72 pubmed
    ..Our findings suggest that CDC25A, but not CDC25B, could be used as an independent prognostic marker for HCC. Our data would also contribute to forward understanding of tumor biology of HCC that is associated with cell cycle regulation. ..
  10. Yamamori E, Iwasaki Y, Oki Y, Yoshida M, Asai M, Kambayashii M, et al. Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion. Endocrinology. 2004;145:36-8 pubmed
    ..These results suggest that ryanodine receptor-mediated calcium-induced calcium release is involved in the regulation of CRH-induced ACTH release. ..
  11. Takeda N, Maemura K, Imai Y, Harada T, Kawanami D, Nojiri T, et al. Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1. Circ Res. 2004;95:146-53 pubmed
    ..Thus, EPAS1 may contribute to the construction of mature vessels by modulating the coordinated expressions of VEGF, Flt-1, Flk-1, and Tie2. ..
  12. Shiina T, Konno A, Oonuma T, Kitamura H, Imaoka K, Takeda N, et al. Targeted disruption of MAIL, a nuclear IkappaB protein, leads to severe atopic dermatitis-like disease. J Biol Chem. 2004;279:55493-8 pubmed
    ..These findings suggest that MAIL is an essential molecule for homeostatic regulation of skin immunity. The Mail-/- mouse is a valuable new animal model for research on AD. ..
  13. Yoshitsugu H, Nishimura M, Tateno C, Kataoka M, Takahashi E, Soeno Y, et al. Evaluation of human CYP1A2 and CYP3A4 mRNA expression in hepatocytes from chimeric mice with humanized liver. Drug Metab Pharmacokinet. 2006;21:465-74 pubmed
    ..In conclusion, we demonstrated that expression and induction of human CYPs in human hepatocytes can be reproduced in chimeric mouse hepatocytes. ..
  14. Ando T, Ishiguro H, Kimura M, Mitsui A, Mori Y, Sugito N, et al. The overexpression of caveolin-1 and caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma. Oncol Rep. 2007;18:601-9 pubmed
    ..0105 and 0.0424 for CAV1 and CAV2, respectively). These results suggest that positive staining for CAV1 and CAV2 could be a potentially useful prognostic marker of ESCC. ..
  15. Tsubaki M, Kato C, Nishinobo M, Ogaki M, Satou T, Ito T, et al. Nitrogen-containing bisphosphonate, YM529/ONO-5920, inhibits macrophage inflammatory protein 1 alpha expression and secretion in mouse myeloma cells. Cancer Sci. 2008;99:152-8 pubmed
    ..Accordingly, YM529/ONO-5920 appears to have promise for use in effective future therapy for osteolysis and myeloma cell growth that depends on MIP-1 alpha. ..
  16. Sugiura T, Kato Y, Wakayama T, Silver D, Kubo Y, Iseki S, et al. PDZK1 regulates two intestinal solute carriers (Slc15a1 and Slc22a5) in mice. Drug Metab Dispos. 2008;36:1181-8 pubmed publisher
    ..These findings also raise the possibility that intestinal absorption of the substrate drugs for PEPT1 and OCTN2 is governed by the protein network of these transporters and their adaptor PDZK1. ..
  17. Usui T, Yanagihara K, Tsukasaki K, Murata K, Hasegawa H, Yamada Y, et al. Characteristic expression of HTLV-1 basic zipper factor (HBZ) transcripts in HTLV-1 provirus-positive cells. Retrovirology. 2008;5:34 pubmed publisher
    ..HBZs consisting of non-spliced and spliced isoforms (HBZ-SI) are thought to be implicated in viral replication and T-cell proliferation but there is little evidence on the HBZ expression profile on a large scale...
  18. Kanasaki H, Mutiara S, Oride A, Purwana I, Miyazaki K. Pulse frequency-dependent gonadotropin gene expression by adenylate cyclase-activating polypeptide 1 in perifused mouse pituitary gonadotroph LbetaT2 cells. Biol Reprod. 2009;81:465-72 pubmed publisher
    ..This regulation may involve alteration in numbers of GnRH and ADCYAP1 receptors as well as FST expression. ..
  19. Hagiwara Y, Ando A, Chimoto E, Tsuchiya M, Takahashi I, Sasano Y, et al. Expression of collagen types I and II on articular cartilage in a rat knee contracture model. Connect Tissue Res. 2010;51:22-30 pubmed publisher
    ..Alterations of collagen types I and II expression may also affect the degeneration of articular cartilage after immobilization and the changes were different in the three areas. ..
  20. Yoshida M, Hayashi H, Taira M, Isono K. Elevated expression of the ornithine decarboxylase gene in human esophageal cancer. Cancer Res. 1992;52:6671-5 pubmed
    ..Mechanisms sustaining high ODC mRNA levels in esophageal cancers may be an enhancement of the promoter activity of this gene or stabilization of the mRNA. ..
  21. Tomomura M, Imamura Y, Horiuchi M, Koizumi T, Nikaido H, Hayakawa J, et al. Abnormal expression of urea cycle enzyme genes in juvenile visceral steatosis (jvs) mice. Biochim Biophys Acta. 1992;1138:167-71 pubmed
    ..These results suggest that jvs affects not only the regulation of the tissue-specific expression of the urea cycle enzymes but also the regulation of their developmental induction. ..
  22. Nakayama K, Kawachi Y, Tokito S, Minami N, Yamamoto R, Imai T, et al. Recent duplication of the two human CD8 beta-chain genes. J Immunol. 1992;148:1919-27 pubmed
  23. Sakai N, Mori S, Izumi S, Haino Fukushima K, Ogura T, Maekawa H, et al. Structures and expression of mRNAs coding for major plasma proteins of Bombyx mori. Biochim Biophys Acta. 1988;949:224-32 pubmed
  24. Kubo Y, Nakagawa Y, Kakimi K, Matsui H, Higo K, Wang L, et al. Molecular cloning and characterization of a murine AIDS virus-related endogenous transcript expressed in C57BL/6 mice. J Gen Virol. 1994;75 ( Pt 4):881-8 pubmed
    ..The recombinant virus was replication-competent, and the p12 region of the transcript retained the functional sequence present in the BM5eco virus. ..
  25. Itoh S, Yoshimura T, Iemura O, Yamada E, Tsujikawa K, Kohama Y, et al. Molecular cloning of 25-hydroxyvitamin D-3 24-hydroxylase (Cyp-24) from mouse kidney: its inducibility by vitamin D-3. Biochim Biophys Acta. 1995;1264:26-8 pubmed
    ..1 and 94.7% amino acid identity with human and rat CYP24s, respectively. Among mouse organs examined, Cyp-24 mRNA could be detected in the kidney. When mice were treated with vitamin D-3, Cyp-24 mRNA was induced in the kidney. ..
  26. Fujimoto J, Hori M, Ichigo S, Misao R, Tamaya T. Preliminary study of oncogene expressions in endometrial cancers. Aberrant estrogen receptor gene and erbB-2 expressions. Eur J Gynaecol Oncol. 1995;16:40-7 pubmed
  27. Yoshihara Y, Oka S, Nemoto Y, Watanabe Y, Nagata S, Kagamiyama H, et al. An ICAM-related neuronal glycoprotein, telencephalin, with brain segment-specific expression. Neuron. 1994;12:541-53 pubmed
    ..TLN is an example of a dendrite-associated cell adhesion molecule involved in the brain's segmental organization, cell-cell interactions during dendritic development, and maintenance of functional neuronal networks. ..
  28. Imaizumi K, Tsuda M, Wanaka A, Tohyama M, Takagi T. Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury. Brain Res Mol Brain Res. 1994;26:189-96 pubmed
  29. Sugiyama A, Tanaka K, Okazaki K, Nojima H, Okayama H. A zinc finger protein controls the onset of premeiotic DNA synthesis of fission yeast in a Mei2-independent cascade. EMBO J. 1994;13:1881-7 pubmed
    ..Thus, rep1+ controls the initiation of premeiotic DNA synthesis via induction and/or activation of Res2 and some other essential factors in a cascade independent of Mei2. ..
  30. Okamoto N, Hori S, Akazawa C, Hayashi Y, Shigemoto R, Mizuno N, et al. Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction. J Biol Chem. 1994;269:1231-6 pubmed
    ..mGluR7 together with mGluR4 thus corresponds to the putative L-2-amino-4-phosphonobutyrate receptor which plays an important role in modulation of glutamate transmission in the central nervous system. ..
  31. Kinoh H, Sato H, Tsunezuka Y, Takino T, Kawashima A, Okada Y, et al. MT-MMP, the cell surface activator of proMMP-2 (pro-gelatinase A), is expressed with its substrate in mouse tissue during embryogenesis. J Cell Sci. 1996;109 ( Pt 5):953-9 pubmed
    ..These results indicated that proMMP-2 activation through its activator, MT-MMP, is a physiological system used by organisms to initiate tissue remodeling on the cell surface. ..
  32. Fan Q, Yuasa S, Kuno N, Senda T, Kobayashi M, Muramatsu T, et al. Expression of basigin, a member of the immunoglobulin superfamily, in the mouse central nervous system. Neurosci Res. 1998;30:53-63 pubmed
    ..Taking into account that Bsg knockout mice exhibit abnormalities in behavior, but a normal blood-brain barrier function, the present findings suggest that Bsg functions actively in neuronal interactions in the central nervous system. ..
  33. Kubota S, Hattori T, Nakanishi T, Takigawa M. Involvement of cis-acting repressive element(s) in the 3'-untranslated region of human connective tissue growth factor gene. FEBS Lett. 1999;450:84-8 pubmed
    ..Together with the fact that several consensus sequences for regulatory elements are found in it, these results suggest the involvement of multiple sets of regulatory elements in the CTGF 3'-UTR. ..
  34. Matsumoto M, Kamohara M, Sugimoto T, Hidaka K, Takasaki J, Saito T, et al. The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors. Gene. 2000;248:183-9 pubmed
    ..1-5p14. Transient expression of SALPR in COS-1 cells did not produce any binding sites for somatostatin or angiotensin II, indicating the necessity for further study to discover its ligand and physiological significance. ..
  35. Maung K, Miyazaki A, Nomiyama H, Chang C, Chang T, Horiuchi S. Induction of acyl-coenzyme A:cholesterol acyltransferase-1 by 1,25-dihydroxyvitamin D(3) or 9-cis-retinoic acid in undifferentiated THP-1 cells. J Lipid Res. 2001;42:181-7 pubmed
    ..0-fold by using 100 nM 1,25-(OH)(2)D(3), and 1.8-fold by using 1 microM 9-cis-RA. Together, our results suggest that 1,25-(OH)(3) participates in ACAT-1 gene expression during the monocyte-macrophage differentiation process. ..
  36. Matsuda S, Tani Y, Yamada M, Yoshimura K, Arizono N. Type 2-biased expression of cytokine genes in lung granulomatous lesions induced by Nippostrongylus brasiliensis infection. Parasite Immunol. 2001;23:219-26 pubmed
    ..RMCP II immunohistochemistry revealed that mast cells increased in number in the lung granulomas. From these results, it was concluded that the nematode infection-associated lung granuloma was a type 2 lesion...
  37. Maeda S, Ishidou Y, Koga H, Taketomi E, Ikari K, Komiya S, et al. Functional impact of human collagen alpha2(XI) gene polymorphism in pathogenesis of ossification of the posterior longitudinal ligament of the spine. J Bone Miner Res. 2001;16:948-57 pubmed
  38. Ohtsuka Y, Obinata T, Okamura Y. Induction of ascidian peripheral neuron by vegetal blastomeres. Dev Biol. 2001;239:107-17 pubmed
    ..26 blastomeres aligning on the edge of presumptive neural region where ascidian homologue of Pax3 is expressed. These findings highlight the close similarity of ascidian ESNs development with that of vertebrate placode and neural crest. ..
  39. Narahara M, Yamada A, Hamada Kanazawa M, Kawai Y, Miyake M. cDNA cloning of the Sry-related gene Sox6 from rat with tissue-specific expression. Biol Pharm Bull. 2002;25:705-9 pubmed
    ..The rSox6 was expressed in the neonatal brain and adult testis as well as by Northern blotting and also expressed in the adult eyeball and slightly in the ovary. ..
  40. Nishimine M, Nakamura M, Kishi M, Okamoto M, Shimada K, Ishida E, et al. Alterations of p14ARF and p16INK4a genes in salivary gland carcinomas. Oncol Rep. 2003;10:555-60 pubmed
  41. Namekawa S, Hamada F, Sawado T, Ishii S, Nara T, Ishizaki T, et al. Dissociation of DNA polymerase alpha-primase complex during meiosis in Coprinus cinereus. Eur J Biochem. 2003;270:2137-46 pubmed
    ..These results suggest that the form of the DNA polymerase alpha-primase complex is altered during meiotic development...
  42. Yamamoto T, Nishizaki I, Nukada T, Kamegaya E, Furuya S, Hirabayashi Y, et al. Functional identification of ASCT1 neutral amino acid transporter as the predominant system for the uptake of L-serine in rat neurons in primary culture. Neurosci Res. 2004;49:101-11 pubmed
    ..Taken together, these findings indicate that ASCT1 predominantly contributes to the uptake of L-serine in primary neurons. ..
  43. Horinouchi K, Nakamura Y, Yamanaka H, Watabe T, Shiosaka S. Distribution of L1cam mRNA in the adult mouse brain: In situ hybridization and Northern blot analyses. J Comp Neurol. 2005;482:386-404 pubmed
    ..Some long projection neurons such as the pyramidal, mitral, principal neurons of several cranial nuclei, and presumably monoaminergic cells containing noradrenalin, dopamine, and serotonin, expressed high levels of L1cam. ..
  44. Takimoto Ohnishi E, Saito T, Ishida J, Ohnishi J, Sugiyama F, Yagami K, et al. Differential roles of renin and angiotensinogen in the feto-maternal interface in the development of complications of pregnancy. Mol Endocrinol. 2005;19:1361-72 pubmed
    ..This study provides in vivo evidence that the cell-specific expression of RN and ANG in the feto-maternal interface impacts their differential roles in pregnancy. ..
  45. Yoshida J, Tani T. Hsp16p is required for thermotolerance in nuclear mRNA export in fission yeast Schizosaccharomyces pombe. Cell Struct Funct. 2005;29:125-38 pubmed
    ..We also found that Hsp16p, the expression of which is controlled by Atf1p, is involved in acquisition of thermotolerance in mRNA export in S. pombe. ..
  46. Tomita M, Okuyama T, Katsuyama H, Miura Y, Nishimura Y, Hidaka K, et al. Mouse model of paraquat-poisoned lungs and its gene expression profile. Toxicology. 2007;231:200-9 pubmed
    ..These changes in gene expression, which are equalled to functional activities of proteins, will be the targets for future studies focused on the development on PQ-induced pulmonary damage. ..
  47. Hashimoto H, Sudo T, Mikami Y, Otani M, Takano M, Tsuda H, et al. Germ cell specific protein VASA is over-expressed in epithelial ovarian cancer and disrupts DNA damage-induced G2 checkpoint. Gynecol Oncol. 2008;111:312-9 pubmed publisher
    ..These results suggest that VASA may either play a direct role in the progression of EOC or serve as a valuable marker of tumorigenesis. ..
  48. Kizaki K, Ushizawa K, Takahashi T, Yamada O, Todoroki J, Sato T, et al. Gelatinase (MMP-2 and -9) expression profiles during gestation in the bovine endometrium. Reprod Biol Endocrinol. 2008;6:66 pubmed publisher
    ..In cows, as is the case in humans and rodents, gelatinases participate in endometrial remodeling, and their activities depend on the balance of activators and inhibitors; i.e., TIMP, MT-MMP, EMMPRIN, MMP-2, MMP-9, and so on. ..
  49. Karim N, Jones J, Okada H, Kikuchi T. Analysis of expressed sequence tags and identification of genes encoding cell-wall-degrading enzymes from the fungivorous nematode Aphelenchus avenae. BMC Genomics. 2009;10:525 pubmed publisher
    ..Expressed sequence tag (EST) analysis may therefore be useful in providing an initial insight into the poorly understood genetic background of A. avenae...
  50. Saito M, Yoshida K, Hibi M, Taga T, Kishimoto T. Molecular cloning of a murine IL-6 receptor-associated signal transducer, gp130, and its regulated expression in vivo. J Immunol. 1992;148:4066-71 pubmed
    ..Administration of IL-6 in mouse caused up-regulation of the gp130 mRNA levels in several tissues. Both gp130 and IL-6R mRNA in liver were up-regulated in vivo by IL-6. ..
  51. Atomi Y, Yamada S, Nishida T. Early changes of alpha B-crystallin mRNA in rat skeletal muscle to mechanical tension and denervation. Biochem Biophys Res Commun. 1991;181:1323-30 pubmed
    ..Based upon these Northern blot analysis of alpha B-crystallin, nerve innervation and external load on muscle are essential regulatory factors on the expression of the mRNA of alpha B-crystallin in rat skeletal muscle. ..
  52. Imai Y, Kohsaka S. Structure of rat annexin V gene and molecular diversity of its transcripts. Eur J Biochem. 1995;232:327-34 pubmed
    ..We also demonstrated the presence of at least four species of rat annexin V transcripts that were generated by distinct transcription initiation and alternative splicing. ..
  53. Akao Y, Marukawa O, Morikawa H, Nakao K, Kamei M, Hachiya T, et al. The rck/p54 candidate proto-oncogene product is a 54-kilodalton D-E-A-D box protein differentially expressed in human and mouse tissues. Cancer Res. 1995;55:3444-9 pubmed
    ..In addition, the rck/p54 protein was localized to cytoplasm by immunostaining with the use of laser microscopy and by subcellular fractionation. ..
  54. Saito M, Sugimoto T, Tahara A, Kawashima H. Molecular cloning and characterization of rat V1b vasopressin receptor: evidence for its expression in extra-pituitary tissues. Biochem Biophys Res Commun. 1995;212:751-7 pubmed
    ..This finding raises the possibility that V1b may play a role in regulating cell functions of these tissues. ..
  55. Akimoto S, Ono T, Tsutsui H, Kinouchi T, Kataoka K, Ohnishi Y. Complete sequence of the Bacteroides fragilis YCH46 neuraminidase-encoding gene. Biochem Biophys Res Commun. 1994;203:914-21 pubmed
    ..Northern blot analysis using an internal nanH probe revealed a single mRNA species with a length of 1.8 kb that could encode just the neuraminidase. ..
  56. Yoshikawa S, Miyamoto I, Aruga J, Furuichi T, Okano H, Mikoshiba K. Isolation of a Drosophila gene encoding a head-specific guanylyl cyclase. J Neurochem. 1993;60:1570-3 pubmed
    ..The enriched distribution in the eye suggests that dgc1 may have a role in phototransduction. ..
  57. Yu S, Ozawa M, Naved A, Miyauchi T, Muramatsu H, Muramatsu T. cDNA cloning and sequence analysis of a novel calcium binding protein with oligoproline motif. Cell Struct Funct. 1995;20:263-8 pubmed
    ..The cDNA was translated as a fusion protein with glutathione-S-transferase, and was verified to have calcium binding activity, upon a calcium blot experiment. ..
  58. Honda H, Yamashita Y, Ozawa K, Mano H. Cloning and characterization of mouse tec promoter. Biochem Biophys Res Commun. 1996;223:422-6 pubmed
    ..The promoter activity of the 5' flanking region was confirmed by using the luciferase assay. The present analysis will provide insights into the mechanism for the expression and regulation of the Tec molecule. ..
  59. Shiratori A, Shibata T, Arisawa M, Hanaoka F, Murakami Y, Eki T. Systematic identification, classification, and characterization of the open reading frames which encode novel helicase-related proteins in Saccharomyces cerevisiae by gene disruption and Northern analysis. Yeast. 1999;15:219-53 pubmed
    ..This suggests that helicase-like genes may be involved in the biosynthesis of nucleic acids and proteins, and that the genes can be transcriptionally activated by heat shock to compensate for the repressed synthesis of mRNA and protein. ..
  60. Tojo M, Mori T, Kiyosawa H, Honma Y, Tanno Y, Kanazawa K, et al. Expression of sonic hedgehog signal transducers, patched and smoothened, in human basal cell carcinoma. Pathol Int. 1999;49:687-94 pubmed
  61. Fujii R, Hosoya M, Fukusumi S, Kawamata Y, Habata Y, Hinuma S, et al. Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3. J Biol Chem. 2000;275:21068-74 pubmed
    ..The identification of a specific and functional receptor for neuromedin U will facilitate studies on their physiological roles and the search for receptor agonists and antagonists. ..
  62. Watabe K, Ida H, Uehara K, Oyanagi K, Sakamoto T, Tanaka J, et al. Establishment and characterization of immortalized Schwann cells from murine model of Niemann-Pick disease type C (spm/spm). J Peripher Nerv Syst. 2001;6:85-94 pubmed
    ..These immortalized Schwann cells can be useful in studies on the nervous system lesions in NPC. ..
  63. Tabuchi I, Soramoto S, Nemoto N, Husimi Y. An in vitro DNA virus for in vitro protein evolution. FEBS Lett. 2001;508:309-12 pubmed
    ..Due to intactness of mRNA, this type of in vitro DNA virus will take the next step toward in vitro autonomous evolution, just like in vivo viral evolution in a cellstat. ..
  64. Xiang A, Uchida Y, Nomura A, Iijima H, Sakamoto T, Ishii Y, et al. Involvement of thromboxane A(2) in airway mucous cells in asthma-related cough. J Appl Physiol (1985). 2002;92:763-70 pubmed
    ..These results suggest that TxA(2) derived from mucous cells potentiated cough responses to capsaicin in allergic airway inflammation...
  65. Hiwasa K, Kinugasa Y, Amano S, Hashimoto A, Nakano R, Inaba A, et al. Ethylene is required for both the initiation and progression of softening in pear (Pyrus communis L.) fruit. J Exp Bot. 2003;54:771-9 pubmed
    ..The results suggest that ethylene is required for PGs expression even in the late ripening stage, but not for EGases...
  66. Nakagawa T, Takane K, Sugimoto T, Izui K, Kouchi H, Hata S. Regulatory regions and nuclear factors involved in nodule-enhanced expression of a soybean phosphoenolpyruvate carboxylase gene: implications for molecular evolution. Mol Genet Genomics. 2003;269:163-72 pubmed
    ..This study suggests that the acquisition of two interdependent cis-acting elements resulted in molecular evolution of the nodule-enhanced GmPEPC7gene. ..
  67. Suzuki A, Iwama A, Miyashita H, Nakauchi H, Taniguchi H. Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells. Development. 2003;130:2513-24 pubmed
    ..These are the first findings to illustrate the mechanism of hepatic stem cell differentiation in liver development. ..
  68. Kanno K, Tazuma S, Chayama K. AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4). Biochem Biophys Res Commun. 2003;308:177-83 pubmed
    ..The level of transforming growth factor-beta 1 (TGF-beta 1) messenger RNA was markedly higher in WT mice when compared with AT1A-deficient mice. These results confirm that signaling via AT1A plays a pivotal role in hepatic fibrogenesis. ..
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