Experts and Doctors on messenger rna in Germany


Locale: Germany
Topic: messenger rna

Top Publications

  1. Wetzstein M, Volker U, Dedio J, Löbau S, Zuber U, Schiesswohl M, et al. Cloning, sequencing, and molecular analysis of the dnaK locus from Bacillus subtilis. J Bacteriol. 1992;174:3300-10 pubmed
    ..The biological property of this inverted repeat as a putative key element in the induction of heat shock genes is discussed. The dnaK locus was mapped at about 223 degrees on the B. subtilis genetic map. ..
  2. Stolt P, Zillig W. Antisense RNA mediates transcriptional processing in an archaebacterium, indicating a novel kind of RNase activity. Mol Microbiol. 1993;7:875-82 pubmed
    ..The single-stranded ends of RNA are cut off at the ends of the 151 nt RNA duplex, removing the ribosomal binding sites from the first open reading frame of transcript T1 but without concomitant digestion of the products. ..
  3. Keck U, Nedellec P, Beauchemin N, Thompson J, Zimmermann W. The cea10 gene encodes a secreted member of the murine carcinoembryonic antigen family and is expressed in the placenta, gastrointestinal tract and bone marrow. Eur J Biochem. 1995;229:455-64 pubmed
    ..Taken together, Cea10 combines characteristic features of both CEA and PSG subgroup members in its structure and expression pattern. ..
  4. Bockers T, Nieschlag E, Kreutz M, Bergmann M. Localization of follicle-stimulating hormone (FSH) immunoreactivity and hormone receptor mRNA in testicular tissue of infertile men. Cell Tissue Res. 1994;278:595-600 pubmed
  5. Schorpp M, Jager R, Schellander K, Schenkel J, Wagner E, Weiher H, et al. The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice. Nucleic Acids Res. 1996;24:1787-8 pubmed
  6. Reuss B, Hellmann P, Traub O, Butterweck A, Winterhager E. Expression of connexin31 and connexin43 genes in early rat embryos. Dev Genet. 1997;21:82-90 pubmed
    ..THus, connexin31 seems not to be related to the first step in trophoblast lineage development and could serve as a compensatory channel during preimplantation development. ..
  7. Meissner W, Rothfels H, Schafer B, Seifart K. Development of an inducible pol III transcription system essentially requiring a mutated form of the TATA-binding protein. Nucleic Acids Res. 2001;29:1672-82 pubmed
    ..This system may conceptually be used in the future to inducibly express an arbitrary DNA sequence in vivo under the control of the above mentioned promoter. ..
  8. Papenbrock J, Mishra S, Mock H, Kruse E, Schmidt E, Petersmann A, et al. Impaired expression of the plastidic ferrochelatase by antisense RNA synthesis leads to a necrotic phenotype of transformed tobacco plants. Plant J. 2001;28:41-50 pubmed
    ..By means of the specifically diminished ferrochelatase activity consequences of the selective inhibition of protoheme formation for the intracellular supply of heme can be investigated in the future...
  9. Sasaki T, Giltay R, Talts U, Timpl R, Talts J. Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach. Exp Cell Res. 2002;275:185-99 pubmed
    ..This was in part due to epitope masking for monoclonal antibodies commonly used in previous studies in esophagus, intestine, stomach, liver, kidney, and spleen. ..

More Information

Publications437 found, 100 shown here

  1. Heidbreder M, Fröhlich F, Jöhren O, Dendorfer A, Qadri F, Dominiak P. Hypoxia rapidly activates HIF-3alpha mRNA expression. FASEB J. 2003;17:1541-3 pubmed
    ..Our results suggest that induction at the transcriptional level is a unique feature of HIF-3alpha, which therefore may represent a rapidly reacting component of the HIF system in protection against hypoxic damage. ..
  2. Görögh T, Berwig J, Scola N, Lippert B. Differential regulation of MAPK (JNK 3) gene expression in human head and neck squamous cell carcinomas. Onkologie. 2004;27:353-7 pubmed
    ..The JNK 3 gene encodes a protein which belongs to the mitogen-activated protein (MAP) kinases, a group of molecules involved in signaling pathways...
  3. Vujic Spasic M, Kiss J, Herrmann T, Kessler R, Stolte J, Galy B, et al. Physiologic systemic iron metabolism in mice deficient for duodenal Hfe. Blood. 2007;109:4511-7 pubmed
  4. Schmutzler C, Mentrup B, Schomburg L, Hoang Vu C, Herzog V, Köhrle J. Selenoproteins of the thyroid gland: expression, localization and possible function of glutathione peroxidase 3. Biol Chem. 2007;388:1053-9 pubmed
    ..Particularly, GPx3 might use excess H2O2 and catalyze the polymerization of thyroglobulin to the highly cross-linked storage form present in the colloid. ..
  5. Schmid H, Pfeiffer Guglielmi B, Dolderer B, Thiess U, Verleysdonk S, Hamprecht B. Expression of the brain and muscle isoforms of glycogen phosphorylase in rat heart. Neurochem Res. 2009;34:581-6 pubmed publisher
    ..GP MM was also detected in interstitial cells identified as fibroblasts. The physiological role of co-expression of GP BB and GP MM in cardiomyocytes and in brain astrocytes is discussed in a comparative way. ..
  6. Homuth G, Masuda S, Mogk A, Kobayashi Y, Schumann W. The dnaK operon of Bacillus subtilis is heptacistronic. J Bacteriol. 1997;179:1153-64 pubmed
    ..Blocking transcription of the suboperon from the upstream heat-inducible promoter did not impair growth and viability at high temperatures. ..
  7. Fortes P, Kufel J, Fornerod M, Polycarpou Schwarz M, Lafontaine D, Tollervey D, et al. Genetic and physical interactions involving the yeast nuclear cap-binding complex. Mol Cell Biol. 1999;19:6543-53 pubmed
    ..Mutants lacking yCBC were found to be defective in rRNA processing. Analysis of the yCBC deletion phenotype suggests that this is likely to be due to a defect in the splicing of a subset of ribosomal protein mRNA precursors. ..
  8. Ludwig A, Tenhaken R. Defence gene expression in soybean is linked to the status of the cell death program. Plant Mol Biol. 2000;44:209-18 pubmed
    ..Consistent with these findings a HR-specific marker gene is neither directly induced by H2O2 or SA. However, this gene shows a high expression in the regular HR and is induced much faster in the SA-accelerated PCD. ..
  9. Giehl K, Rohrig S, Bonatz H, Gutjahr M, Leiner B, Bartke I, et al. Endogenous brain-derived neurotrophic factor and neurotrophin-3 antagonistically regulate survival of axotomized corticospinal neurons in vivo. J Neurosci. 2001;21:3492-502 pubmed
    ..We further present evidence that signaling of tyrosine kinase receptors of the trk family can be crucially involved in the promotion of neuronal death in vivo. ..
  10. Bojunga J, Dresar Mayert B, Usadel K, Kusterer K, Zeuzem S. Antioxidative treatment reverses imbalances of nitric oxide synthase isoform expression and attenuates tissue-cGMP activation in diabetic rats. Biochem Biophys Res Commun. 2004;316:771-80 pubmed
    ..Furthermore, our data show that antioxidative treatment is capable of reversing changes in the NO-cGMP system and may therefore be an important therapeutic option for preventing vascular damage in diabetes mellitus. ..
  11. Li Y, Ji A, Weihe E, Schafer M. Cell-specific expression and lipopolysaccharide-induced regulation of tumor necrosis factor alpha (TNFalpha) and TNF receptors in rat dorsal root ganglion. J Neurosci. 2004;24:9623-31 pubmed
    ..This is likely to be relevant under conditions of inflammatory pain and infections accompanied by widespread TNFalpha synthesis and release and may drive sickness behavior. ..
  12. Stieber J, Stöckl G, Herrmann S, Hassfurth B, Hofmann F. Functional expression of the human HCN3 channel. J Biol Chem. 2005;280:34635-43 pubmed
    ..The missing response to cAMP distinguishes human HCN3 from both the well cAMP responding HCN subtypes 2 and 4 and the weak responding subtype 1...
  13. Eckle T, Grenz A, Kohler D, Redel A, Falk M, Rolauffs B, et al. Systematic evaluation of a novel model for cardiac ischemic preconditioning in mice. Am J Physiol Heart Circ Physiol. 2006;291:H2533-40 pubmed
    ..Further studies on cardiac IP using transgenic mice may consider this technique. ..
  14. Vogl C, Klein C, Batke A, Schweingruber M, Stolz J. Characterization of Thi9, a novel thiamine (Vitamin B1) transporter from Schizosaccharomyces pombe. J Biol Chem. 2008;283:7379-89 pubmed publisher
    ..We also found that the pyridoxine transporter Bsu1 has a marked contribution to the thiamine uptake activity of S. pombe cells. ..
  15. Nimz M, Spitschak M, Schneider F, Fürbass R, Vanselow J. Down-regulation of genes encoding steroidogenic enzymes and hormone receptors in late preovulatory follicles of the cow coincides with an accumulation of intrafollicular steroids. Domest Anim Endocrinol. 2009;37:45-54 pubmed publisher
    ..Collectively, our data show that late preovulatory follicles have a transient and unique gene expression profile and are clearly different from both the preceding and subsequent (follicular and luteal, respectively) stages...
  16. Fonseca R, Lynch J, Roth S. Evolution of axis formation: mRNA localization, regulatory circuits and posterior specification in non-model arthropods. Curr Opin Genet Dev. 2009;19:404-11 pubmed publisher
    ..In the end, we try to integrate these new findings with non-model arthropods in a common framework and discuss the major gaps of knowledge that should be addressed by future studies. ..
  17. Heberlein C, Fischer K, Stoffel M, Nowock J, Ford A, Tessmer U, et al. The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: evidence for differentiation stage-specific regulation. Mol Cell Biol. 1992;12:1815-26 pubmed
    ..However, the lack of significant levels of GATA-1 expression in embryonal stem cells implies an alternative regulatory mechanism of EpoR transcription in cells not committed to the hematopoietic lineage. ..
  18. Gutlich M, Schott K, Werner T, Bacher A, Ziegler I. Species and tissue specificity of mammalian GTP cyclohydrolase I messenger RNA. Biochim Biophys Acta. 1992;1171:133-40 pubmed
    ..It shows a 92% identity with the published sequence of the rat gene. The analysis of various human cell lines with this specific probe shows only one species of GTP cyclohydrolase I mRNA with an approximate size of 3.6 kb. ..
  19. Körner C, Wahle E. Poly(A) tail shortening by a mammalian poly(A)-specific 3'-exoribonuclease. J Biol Chem. 1997;272:10448-56 pubmed
    ..The properties of DAN suggest that the enzyme might be involved in the deadenylation of mRNA in vivo. ..
  20. Krause K, Haugwitz U, Wasner M, Wiedmann M, MOssner J, Engeland K. Expression of the cell cycle phosphatase cdc25C is down-regulated by the tumor suppressor protein p53 but not by p73. Biochem Biophys Res Commun. 2001;284:743-50 pubmed
    ..This reveals functional differences between p73 and p53 in regulating cell division. ..
  21. Löffler S, Aust G, Kohler U, Spanel Borowski K. Evidence of leptin expression in normal and polycystic human ovaries. Mol Hum Reprod. 2001;7:1143-9 pubmed
    ..1-B219.3 was identified in granulosa cells and the CL, as well as in the cortex and medulla. We conclude that leptin is produced in the ovary and may act in autocrine and paracrine ways. ..
  22. Becker J, Hertel M, Markmann A, Shahin M, Werner S, Domschke W, et al. Dynamics and localization of activin A expression in rat gastric ulcers. Scand J Gastroenterol. 2003;38:260-7 pubmed
    ..Activin A participates in gastric ulcer healing in a similar fashion as in cutaneous wounding. Its expression on protein and mRNA level is markedly increased in ulcer base and rim. ..
  23. Wu G, Bohn S, Ryffel G. The HNF1beta transcription factor has several domains involved in nephrogenesis and partially rescues Pax8/lim1-induced kidney malformations. Eur J Biochem. 2004;271:3715-28 pubmed
    ..We conclude that HNF1beta has some distinct morphogenetic properties during nephrogenesis. ..
  24. Henneberger C, Jüttner R, Schmidt S, Walter J, Meier J, Rothe T, et al. GluR- and TrkB-mediated maturation of GABA receptor function during the period of eye opening. Eur J Neurosci. 2005;21:431-40 pubmed
    ..Together, these experiments suggest that the GABAAR alpha subunit switch and the associated change in the IPSC kinetics were specifically controlled by NMDAR activity and independent on the signalling through group I mGluRs or TrkB. ..
  25. Ruckert C, Koch D, Rey D, Albersmeier A, Mormann S, Pühler A, et al. Functional genomics and expression analysis of the Corynebacterium glutamicum fpr2-cysIXHDNYZ gene cluster involved in assimilatory sulphate reduction. BMC Genomics. 2005;6:121 pubmed
    ..coli and B. subtilis is used by members of this order, providing the basis for further biochemical studies. ..
  26. Winzen R, Thakur B, Dittrich Breiholz O, Shah M, Redich N, Dhamija S, et al. Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets. Mol Cell Biol. 2007;27:8388-400 pubmed
    ..These results indicate that KSRP functions as a limiting factor in inflammatory gene expression. ..
  27. Matthiesen S, Lindemann D, Warnken M, Juergens U, Racké K. Inhibition of NADPH oxidase by apocynin inhibits lipopolysaccharide (LPS) induced up-regulation of arginase in rat alveolar macrophages. Eur J Pharmacol. 2008;579:403-10 pubmed
    ..Enhanced transcription of arginase mRNA and prolongation of the life time of the active enzyme appear to contribute to the enhanced arginase activity. ..
  28. Weining K, Schultz U, Münster U, Kaspers B, Staeheli P. Biological properties of recombinant chicken interferon-gamma. Eur J Immunol. 1996;26:2440-7 pubmed
  29. Schnieders F, Dork T, Arnemann J, Vogel T, Werner M, Schmidtke J. Testis-specific protein, Y-encoded (TSPY) expression in testicular tissues. Hum Mol Genet. 1996;5:1801-7 pubmed
    ..The data presented here point to a phosphorylation-dependent TSPY-function in early spermatogenesis, immediately prior to the spermatogonia-to-spermatocyte transition, and in early testicular tumorigenesis. ..
  30. Schopfer C, Ebel J. Identification of elicitor-induced cytochrome P450s of soybean (Glycine max L.) using differential display of mRNA. Mol Gen Genet. 1998;258:315-22 pubmed
    ..Consequently, this approach offers a straightforward alternative to classical P450 isolation strategies via protein purification and should prove especially useful for isolating P450s that are expressed at a low level. ..
  31. Mages H, Baag R, Steiner B, Kroczek R. Utilization of an NF-ATp binding promoter element for EGR3 expression in T cells but not fibroblasts provides a molecular model for the lymphoid cell-specific effect of cyclosporin A. Mol Cell Biol. 1998;18:7157-65 pubmed
    ..The differential usage of an NF-AT binding site explains the selective effect of CsA on EGR3 gene expression in T cells versus fibroblasts and may represent one of the basic mechanisms underlying the tissue specificity of CsA. ..
  32. Vassen L, Wegrzyn W, Klein Hitpass L. Human insulin receptor substrate-2 (IRS-2) is a primary progesterone response gene. Mol Endocrinol. 1999;13:485-94 pubmed
  33. Heber S, Herms J, Gajic V, Hainfellner J, Aguzzi A, Rülicke T, et al. Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. J Neurosci. 2000;20:7951-63 pubmed
    ..Moreover, cortical neurons from single or combined mutant mice showed unaltered survival rates under basal culture conditions and unaltered susceptibility to glutamate excitotoxicity in vitro. ..
  34. Mujica A, Hankeln T, Schmidt E. A novel serine/threonine kinase gene, STK33, on human chromosome 11p15.3. Gene. 2001;280:175-81 pubmed
    ..9 (1995) 576]. STK33 shows a differential expression in a variety of normal and malignant tissues. ..
  35. Steinbrenner H, Nguyen T, Wohlrab U, Scherbaum W, Seissler J. Effect of proinflammatory cytokines on gene expression of the diabetes-associated autoantigen IA-2 in INS-1 cells. Endocrinology. 2002;143:3839-45 pubmed
    ..The action of IL-1beta may be partly mediated by the activation of the NO pathway. ..
  36. Kzhyshkowska J, Rusch A, Wolf H, Dobner T. Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7. Biochem J. 2003;371:385-93 pubmed
    ..We conclude that complex formation between BRD7 and E1B-AP5 links chromatin events with mRNA processing at the level of transcriptional regulation. ..
  37. Bahn A, Hauss A, Appenroth D, Ebbinghaus D, Hagos Y, Steinmetzer P, et al. RT-PCR-based evidence for the in vivo stimulation of renal tubularp-aminohippurate (PAH) transport by triiodothyronine (T3) or dexamethasone (DEXA) in kidney tissue of immature and adult rats. Exp Toxicol Pathol. 2003;54:367-73 pubmed
    ..Thus, this is the first evidence that T3 and DEXA pre-treatment induces the expression of OAT1. ..
  38. Kusserow A, Pang K, Sturm C, Hrouda M, Lentfer J, Schmidt H, et al. Unexpected complexity of the Wnt gene family in a sea anemone. Nature. 2005;433:156-60 pubmed
    ..It emphasizes the crucial function of Wnt genes in the diversification of eumetazoan body plans. ..
  39. Sellner J, Dvorak F, Zhou Y, Haas J, Kehm R, Wildemann B, et al. Acute and long-term alteration of chemokine mRNA expression after anti-viral and anti-inflammatory treatment in herpes simplex virus encephalitis. Neurosci Lett. 2005;374:197-202 pubmed
    ..This pattern was substantially altered by anti-viral and anti-inflammatory treatment. Our findings indicate a pivotal role of these chemokines in the immunopathogenesis of HSVE...
  40. Tedeschi A, Nguyen T, Steele S, Feil S, Naumann U, Feil R, et al. The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse. J Neurosci. 2009;29:15155-60 pubmed publisher
    ..In conclusion, this study identifies p53 as a transcription factor that regulates the expression of cGKI during neuronal maturation and cGMP-dependent inhibition of growth cone collapse. ..
  41. Heim C, Abele Ohl S, Eckl S, Ramsperger Gleixner M, Mahmoudian S, Weyand M, et al. Murine cytomegalovirus infection leads to increased levels of transplant arteriosclerosis in a murine aortic allograft model. Transplantation. 2010;90:373-9 pubmed publisher
    ..These data suggest that MCMV infection plays an important role in the development of transplant arteriosclerosis. ..
  42. Körschen H, Illing M, Seifert R, Sesti F, Williams A, Gotzes S, et al. A 240 kDa protein represents the complete beta subunit of the cyclic nucleotide-gated channel from rod photoreceptor. Neuron. 1995;15:627-36 pubmed
    ..Coexpression of the alpha subunit with the full-length beta subunit yields hetero-oligomeric channels with properties characteristic of the native channel. ..
  43. Gutlich M, Witter K, Bourdais J, Veron M, Rödl W, Ziegler I. Control of 6-(D-threo-1',2'-dihydroxypropyl) pterin (dictyopterin) synthesis during aggregation of Dictyostelium discoideum. Involvement of the G-protein-linked signalling pathway in the regulation of GTP cyclohydrolase I activity. Biochem J. 1996;314 ( Pt 1):95-101 pubmed
    ..discoideum. ..
  44. Neun R, Richter M, Staeheli P, Schwemmle M. GTPase properties of the interferon-induced human guanylate-binding protein 2. FEBS Lett. 1996;390:69-72 pubmed
    ..Thus, hGBP1 and hGBP2 have similar biochemical properties, but show pronounced differences in product specificity. ..
  45. Wesche H, Neumann D, Resch K, Martin M. Co-expression of mRNA for type I and type II interleukin-1 receptors and the IL-1 receptor accessory protein correlates to IL-1 responsiveness. FEBS Lett. 1996;391:104-8 pubmed
    ..These results suggest that the expression of the IL-1RAcP correlates with IL-1 responsiveness and they point to a pivotal role for the IL-1RAcP in IL-1 signal generation. ..
  46. Casademunt E, Carter B, Benzel I, Frade J, Dechant G, Barde Y. The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death. EMBO J. 1999;18:6050-61 pubmed
    ..These results indicate that NRIF is an intracellular p75(NTR)-binding protein transducing cell death signals during development. ..
  47. Kohl S, Baumann B, Broghammer M, Jagle H, Sieving P, Kellner U, et al. Mutations in the CNGB3 gene encoding the beta-subunit of the cone photoreceptor cGMP-gated channel are responsible for achromatopsia (ACHM3) linked to chromosome 8q21. Hum Mol Genet. 2000;9:2107-16 pubmed
    ..The 1148delC mutation was identified recurrently in several families, and in total was present on 11 of 22 disease chromosomes segregating in our families...
  48. Wiese S, Breyer T, Dragu A, Wakili R, Burkard T, Schmidt Schweda S, et al. Gene expression of brain natriuretic peptide in isolated atrial and ventricular human myocardium: influence of angiotensin II and diastolic fiber length. Circulation. 2000;102:3074-9 pubmed
    ..The fact that the induction of cardiac growth is inhibited by the blockade of Ang II subtype 1 receptors is of scientific and clinical importance. ..
  49. Koegel H, Alzheimer C. Expression and biological significance of Ca2+-activated ion channels in human keratinocytes. FASEB J. 2001;15:145-154 pubmed
    ..hSK4 might thus play a role in linking changes in membrane potential to the biological fate of keratinocytes. ..
  50. von Lintig J, Dreher A, Kiefer C, Wernet M, Vogt K. Analysis of the blind Drosophila mutant ninaB identifies the gene encoding the key enzyme for vitamin A formation invivo. Proc Natl Acad Sci U S A. 2001;98:1130-5 pubmed
    ..In two independent ninaB alleles, we found mutations in the gene encoding the beta,beta-carotene-15,15'-dioxygenase. These mutations lead to a defect in vitamin A formation and are responsible for blindness of these flies. ..
  51. Fleck M, Zhang H, Kern E, Hsu H, Müller Ladner U, Mountz J. Treatment of chronic sialadenitis in a murine model of Sjögren's syndrome by local fasL gene transfer. Arthritis Rheum. 2001;44:964-73 pubmed
    ..FasL expression was reconstituted by local gene transfer, resulting in significant reduction of infiltrating mononuclear cells, which indicates that local gene transfer of fasL might be a novel treatment for chronic sialadenitis. ..
  52. Pahl A, Zhang M, Kuss H, Szelenyi I, Brune K. Regulation of IL-13 synthesis in human lymphocytes: implications for asthma therapy. Br J Pharmacol. 2002;135:1915-26 pubmed
    ..Characterizing highly potent inhibitors of IL-13 synthesis can be exploited to identify new drugs to treat immunological diseases such as asthma. ..
  53. Pagany M, Jagodic M, Schubart A, Pham Dinh D, Bachelin C, Baron van Evercooren A, et al. Myelin oligodendrocyte glycoprotein is expressed in the peripheral nervous system of rodents and primates. Neurosci Lett. 2003;350:165-8 pubmed
  54. Luo J, Treubert Zimmermann U, Redies C. Cadherins guide migrating Purkinje cells to specific parasagittal domains during cerebellar development. Mol Cell Neurosci. 2004;25:138-52 pubmed
    ..These results show that cadherins can tell early neurons where to integrate in functional brain gray matter, possibly by a cadherin-based homotypic adhesive mechanism. ..
  55. Vollbrandt T, Tiedemann K, El Hallous E, Lin G, Brinckmann J, John H, et al. Consequences of cysteine mutations in calcium-binding epidermal growth factor modules of fibrillin-1. J Biol Chem. 2004;279:32924-31 pubmed
  56. Kiani A, Habermann I, Haase M, Feldmann S, Boxberger S, Sanchez Fernandez M, et al. Expression and regulation of NFAT (nuclear factors of activated T cells) in human CD34+ cells: down-regulation upon myeloid differentiation. J Leukoc Biol. 2004;76:1057-65 pubmed
    ..These results suggest a novel and unexpected role for members of the NFAT transcription factor family in the hematopoietic system. ..
  57. Golks A, Brenner D, Fritsch C, Krammer P, Lavrik I. c-FLIPR, a new regulator of death receptor-induced apoptosis. J Biol Chem. 2005;280:14507-13 pubmed
    ..Taken together, our data demonstrate endogenous expression of c-FLIP(R) and similar roles of c-FLIP(R) and c-FLIP(S) isoforms in death receptor-mediated apoptosis. ..
  58. Panter B, Jose J, Hartmann R. 5alpha-reductase in human embryonic kidney cell line HEK293: evidence for type II enzyme expression and activity. Mol Cell Biochem. 2005;270:201-8 pubmed
    ..Western blot analysis of different fractions of a HEK293 homogenate performed with this antiserum detected a band at 45 kDa in the nuclear and microsomal fraction corresponding to 5alpha-reductase type II protein. ..
  59. Gründemann D, Harlfinger S, Golz S, Geerts A, Lazar A, Berkels R, et al. Discovery of the ergothioneine transporter. Proc Natl Acad Sci U S A. 2005;102:5256-61 pubmed
    ..Moreover, prominent expression of ETT in monocytes and SLC22A4 polymorphism associations suggest a protective role of ET in chronic inflammatory disorders. ..
  60. Ludwig A, Rozhdestvensky T, Kuryshev V, Schmitz J, Brosius J. An unusual primate locus that attracted two independent Alu insertions and facilitates their transcription. J Mol Biol. 2005;350:200-14 pubmed
    ..Thus, the BC200 RNA gene locus attracted two independent Alu insertions during its evolutionary history and provided upstream promoter elements required for their transcription...
  61. Ruhl A, Hoppe S, Frey I, Daniel H, Schemann M. Functional expression of the peptide transporter PEPT2 in the mammalian enteric nervous system. J Comp Neurol. 2005;490:1-11 pubmed
    ..PEPT2-mediated dipeptide transport in enteric glia could contribute to the clearance of neuropeptides in the ENS. In addition, the fluorophore-coupled dipeptide uptake via PEPT2 is a novel vital marker for glial cells in the ENS. ..
  62. Takamiya M, Campos Ortega J. Hedgehog signalling controls zebrafish neural keel morphogenesis via its level-dependent effects on neurogenesis. Dev Dyn. 2006;235:978-97 pubmed
    ..Such differences seem to be created in part by regional effector signalling; the effects of high Hh-signalling on medial neurogenesis can be reversed in accordance to medial Tri/Stbm level, in a polarity independent manner. ..
  63. Algül H, Wagner M, Lesina M, Schmid R. Overexpression of ErbB2 in the exocrine pancreas induces an inflammatory response but not increased proliferation. Int J Cancer. 2007;121:1410-6 pubmed
    ..We conclude that the biological response of ErbB2/RAS signaling depends highly on cellular context...
  64. Kralj A, Gurgui M, König G, van Echten Deckert G. Trichothecenes induce accumulation of glucosylceramide in neural cells by interfering with lactosylceramide synthase activity. Toxicol Appl Pharmacol. 2007;225:113-22 pubmed
    ..Collectively, our results demonstrate that trichodermol and 8-deoxy-trichothecin inhibit LacCer synthase activity in a cell-type-specific manner. ..
  65. Suess B, Weigand J. Engineered riboswitches: overview, problems and trends. RNA Biol. 2008;5:24-9 pubmed
    ..This review will give an overview of recent reports of engineered riboswitches, highlight recent developments and point out trends and problems in the field. ..
  66. Boeuf S, Börger M, Hennig T, Winter A, Kasten P, Richter W. Enhanced ITM2A expression inhibits chondrogenic differentiation of mesenchymal stem cells. Differentiation. 2009;78:108-15 pubmed publisher
  67. Berres M, Trautwein C, Zaldivar M, Schmitz P, Pauels K, Lira S, et al. The chemokine scavenging receptor D6 limits acute toxic liver injury in vivo. Biol Chem. 2009;390:1039-45 pubmed publisher
    ..These results support the importance of post-translational chemokine regulation and describe a new mechanism of immune modulation within the liver. ..
  68. Scheiber I, Mercer J, Dringen R. Copper accumulation by cultured astrocytes. Neurochem Int. 2010;56:451-60 pubmed publisher
    ..However, since some characteristics of the observed copper accumulation are not consistent with Ctr1-mediated copper transport, additional Ctr1-independent mechanism(s) are likely to be involved in astrocytic copper accumulation. ..
  69. Schloss P, Mayser W, Betz H. The putative rat choline transporter CHOT1 transports creatine and is highly expressed in neural and muscle-rich tissues. Biochem Biophys Res Commun. 1994;198:637-45 pubmed
    ..High expression was also seen in the rat embryo along the entire neuraxis and in some non-neuronal tissues. These data establish CHOT1 as a widely expressed rat creatine transporter. ..
  70. Hübner G, Hu Q, Smola H, Werner S. Strong induction of activin expression after injury suggests an important role of activin in wound repair. Dev Biol. 1996;173:490-8 pubmed
    ..Our data provide evidence for a novel function of activin and indicate that--besides TGF beta s themselves--other members of this superfamily might also play an important role in tissue repair. ..
  71. Hippler B, Homuth G, Hoffmann T, Hungerer C, Schumann W, Jahn D. Characterization of Bacillus subtilis hemN. J Bacteriol. 1997;179:7181-5 pubmed
    ..subtilis was obtained. Moreover, B. subtilis hemY did not substitute for hemF hemN deficiency in S. typhimurium. These results indicate the absence of hemF and suggest the presence of a second hemN-like gene in B. subtilis. ..
  72. Kircher S, Ledger S, Hayashi H, Weisshaar B, Schafer E, Frohnmeyer H. CPRF4a, a novel plant bZIP protein of the CPRF family: comparative analyses of light-dependent expression, post-transcriptional regulation, nuclear import and heterodimerisation. Mol Gen Genet. 1998;257:595-605 pubmed
  73. Neuhaus K, Francis K, Rapposch S, Görg A, Scherer S. Pathogenic Yersinia species carry a novel, cold-inducible major cold shock protein tandem gene duplication producing both bicistronic and monocistronic mRNA. J Bacteriol. 1999;181:6449-55 pubmed
    ..The data demonstrate an extraordinary capacity of the psychrotolerant Y. enterocolitica to produce major cold shock proteins upon cold shock. ..
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