Experts and Doctors on manganese compounds in China
Topic: manganese compounds
Zhao F, Cai T, Liu M, Zheng G, Luo W, Chen J. Manganese induces dopaminergic neurodegeneration via microglial activation in a rat model of manganism. Toxicol Sci. 2009;107:156-64 pubmed publisher
..These results suggested that dopaminergic neurons could be damaged by manganese neurotoxicity, and that the activated microglial cells and their associated activation products played an important role in this neurodegenerative process. ..
Li Y, Sun L, Cai T, Zhang Y, Lv S, Wang Y, et al
. alpha-Synuclein overexpression during manganese-induced apoptosis in SH-SY5Y neuroblastoma cells. Brain Res Bull. 2010;81:428-33 pubmed publisher
..In conclusion, our results imply that intracellular alpha-syn overexpression may be responsible for MnCl(2)-induced apoptosis. ..
Cai T, Che H, Yao T, Chen Y, Huang C, Zhang W, et al
. Manganese induces tau hyperphosphorylation through the activation of ERK MAPK pathway in PC12 cells. Toxicol Sci. 2011;119:169-77 pubmed publisher
..Taken together, we found for the first time that the exposure to manganese can cause the hyperphosphorylation of tau, which may be connected with the activation of ERK MAPK. ..
Pan N, Li L, Ding J, Li S, Wang R, Jin Y, et al
. Preparation of graphene oxide-manganese dioxide for highly efficient adsorption and separation of Th(IV)/U(VI). J Hazard Mater. 2016;309:107-15 pubmed publisher
..Those results displayed that the Î±-GOM2 may be utilized as an potential adsorbent for removing and separating Th(IV)/U(VI) ions from aqueous solutions. ..
Wang W, Li D, Ding X, Zhao Q, Chen J, Tian K, et al
. N-Acetylcysteine protects inner ear hair cells and spiral ganglion neurons from manganese exposure by regulating ROS levels. Toxicol Lett. 2017;279:77-86 pubmed publisher
..Furthermore, 20mM NAC may prevent 1mM Mn-induced hair cell loss and axonal degeneration, indicating that NAC could be a promising drug for clinical applications. ..