Experts and Doctors on maltose in Japan


Locale: Japan
Topic: maltose

Top Publications

  1. Iijima I, Hohsaka T. Position-specific incorporation of fluorescent non-natural amino acids into maltose-binding protein for detection of ligand binding by FRET and fluorescence quenching. Chembiochem. 2009;10:999-1006 pubmed publisher
    ..These results demonstrate the usefulness of the position-specific incorporation of fluorescent amino acids in the fluorescence-based detection of protein functions. ..
  2. Makino Y, Omichi K. Sensitive assay of glycogen phosphorylase activity by analysing the chain-lengthening action on a Fluorogenic [corrected] maltooligosaccharide derivative. J Biochem. 2009;146:71-6 pubmed publisher
    ..This method was used to measure the GP activities of crude and purified GP preparations, and was demonstrated to have about 1,000 times greater sensitivity than the spectrophotometric orthophosphate assay. ..
  3. Takeuchi H, Mooi L, Inagaki Y, He P. Hypoglycemic effect of a hot-water extract from defatted sesame (Sesamum indicum L.) seed on the blood glucose level in genetically diabetic KK-Ay mice. Biosci Biotechnol Biochem. 2001;65:2318-21 pubmed
    ..These results indicate that HES and MFH had a reductive effect on the plasma glucose concentration of KK-Ay mice, and this effect is suggested to have been caused by the delayed glucose absorption...
  4. Yamamoto K, Miyake H, Kusunoki M, Osaki S. Crystal structures of isomaltase from Saccharomyces cerevisiae and in complex with its competitive inhibitor maltose. FEBS J. 2010;277:4205-14 pubmed publisher
    ..These features of the isomaltase active site pocket prevent isomalto-oligosaccharides from binding to the active site effectively. ..
  5. Kato H, Kira S, Kawamukai M. The transcription factors Atf1 and Pcr1 are essential for transcriptional induction of the extracellular maltase Agl1 in fission yeast. PLoS ONE. 2013;8:e80572 pubmed publisher
    ..In addition, the association of Mediator with these genes was dependent on Atf1 and Pcr1. These data indicate that Atf1 and Pcr1 induce the transcription of agl1, which allows efficient utilization of extracellular maltose. ..
  6. Matsui I, Ishikawa K, Miyairi S, Fukui S, Honda K. A mutant alpha-amylase with enhanced activity specific for short substrates. FEBS Lett. 1992;310:216-8 pubmed
  7. Sazuka T, Tomooka Y, Ikawa Y, Noda M, Kumar S. DRG: a novel developmentally regulated GTP-binding protein. Biochem Biophys Res Commun. 1992;189:363-70 pubmed
    ..Based on these observations, we propose that DRG represents an evolutionarily conserved novel class of GTP-binding protein which may play an important role in cell physiology. ..
  8. Matsui I, Ishikawa K, Miyairi S, Fukui S, Honda K. Alteration of bond-cleavage pattern in the hydrolysis catalyzed by Saccharomycopsis alpha-amylase altered by site-directed mutagenesis. Biochemistry. 1992;31:5232-6 pubmed
    ..The reduced catalytic activity specifically for the short substrates is also attributable to the remarkable decrease in the affinity of the 8th subsite...
  9. Lee L, Imae Y. Role of threonine residue 154 in ligand recognition of the tar chemoreceptor in Escherichia coli. J Bacteriol. 1990;172:377-82 pubmed
    ..Thus, these threonine residues seem to have a common role in detecting the aspartate and serine attractant families. A mechanism by which these chemoreceptors detect the amino acid attractants is discussed. ..

More Information


  1. Tanaka T, Furukawa F, Imamura S. Epitope mapping for epidermolysis bullosa acquisita autoantibody by molecularly cloned cDNA for type VII collagen. J Invest Dermatol. 1994;102:706-9 pubmed
    ..These data suggest that multiple epitopes on the N-terminal non-collagenous domain of type VII collagen are recognized by circulating autoantibodies in patients with epidermolysis bullosa acquisita. ..
  2. De Costa D, Suzuki K, Yoshida K. Structural and functional analysis of a putative gene cluster for palatinose transport on the linear chromosome of Agrobacterium tumefaciens MAFF301001. J Bacteriol. 2003;185:2369-73 pubmed
    ..Growth on trehalose and maltose was not influenced by the mutations...
  3. Ooya T, Eguchi M, Yui N. Supramolecular design for multivalent interaction: maltose mobility along polyrotaxane enhanced binding with concanavalin A. J Am Chem Soc. 2003;125:13016-7 pubmed
    ..Therefore, we concluded that the high mobility of maltose groups along the polyrotaxane structure contributes to enhanced Con A recognition. ..
  4. Tokita Y, Satoh K, Sakaguchi M, Endoh Y, Mori I, Yuzurihara M, et al. The preventive effect of Daikenchuto on postoperative adhesion-induced intestinal obstruction in rats. Inflammopharmacology. 2007;15:65-6 pubmed
    ..Furthermore, HS was found to be one of the active compound of DKT, and its action was mediated by sensory nerves. ..
  5. Tokita Y, Yuzurihara M, Sakaguchi M, Satoh K, Kase Y. The pharmacological effects of Daikenchuto, a traditional herbal medicine, on delayed gastrointestinal transit in rat postoperative ileus. J Pharmacol Sci. 2007;104:303-10 pubmed
    ..Moreover, zanthoxylum fruit and maltose syrup were crucial medical herbs contributing to the ability of Daikenchuto. ..
  6. Kawakami K, Sumitani C, Yoshihashi Y, Yonemochi E, Terada K. Investigation of the dynamic process during spray-drying to improve aerodynamic performance of inhalation particles. Int J Pharm. 2010;390:250-9 pubmed publisher
    ..This excipient approach seems to be a promising method to prepare fine drug particles of high dispersity for achieving an efficient pulmonary drug delivery. ..
  7. Yamamoto K, Miyake H, Kusunoki M, Osaki S. Steric hindrance by 2 amino acid residues determines the substrate specificity of isomaltase from Saccharomyces cerevisiae. J Biosci Bioeng. 2011;112:545-50 pubmed publisher
    ..Two isomaltase mutant enzymes - V216T and Q279A - hydrolyzed maltose. Thus, the amino acid residues at these positions may be largely responsible for determining the substrate specificity of ?-glucosidases. ..