Experts and Doctors on macular degeneration in Sweden
Topic: macular degeneration
Eksandh L, Ekstrom U, Abrahamson M, Bauer B, Andreasson S. Different clinical expressions in two families with Stargardt's macular dystrophy (STGD1). Acta Ophthalmol Scand. 2001;79:524-30 pubmed
..To describe the clinical expressions, with emphasis on electrophysiological examinations, in two Swedish families with Stargardt's macular dystrophy (STGD1)...
Nilsson U, Frennesson C, Nilsson S. Patients with AMD and a large absolute central scotoma can be trained successfully to use eccentric viewing, as demonstrated in a scanning laser ophthalmoscope. Vision Res. 2003;43:1777-87 pubmed
..0+/-5.8 words/min. With training (mean 5.2 hours), it increased significantly (p<0.001) to 68.3+/-19.4 words per min. Training of eccentric reading has thus proved to be very successful...
Fu Z, Liegl R, Wang Z, Gong Y, Liu C, Sun Y, et al
. Adiponectin Mediates Dietary Omega-3 Long-Chain Polyunsaturated Fatty Acid Protection Against Choroidal Neovascularization in Mice. Invest Ophthalmol Vis Sci. 2017;58:3862-3870 pubmed publisher
..Modulating the APN pathway in conjunction with a Ï‰3-LCPUFA-enriched-diet may augment the beneficial effects of Ï‰3-LCPUFA in AMD patients. ..
Forsman K, Graff C, Nordstrom S, Johansson K, Westermark E, Lundgren E, et al
. The gene for Best's macular dystrophy is located at 11q13 in a Swedish family. Clin Genet. 1992;42:156-9 pubmed
..A lod score of 15.12 was obtained at recombination fraction 0.01 with DNA marker INT2 (also called FGF3). The retinally expressed gene ROM1, which maps to the same chromosomal region is a candidate for this genetic disease. ..
Sjöberg A, Trouw L, Clark S, Sjölander J, Heinegard D, Sim R, et al
. The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells. J Biol Chem. 2007;282:10894-900 pubmed
..The variations in binding affinity of the two alleles indicate that complement activation and local inflammation in response to different targets will differ between His/His and Tyr/Tyr homozygotes. ..
Gong Y, Fu Z, Liegl R, Chen J, Hellstrom A, Smith L. ?-3 and ?-6 long-chain PUFAs and their enzymatic metabolites in neovascular eye diseases. Am J Clin Nutr. 2017;106:16-26 pubmed publisher
..This review summarizes our current understanding of the roles of ?-3 and ?-6 LC-PUFAs and their enzymatic metabolites in neovascular eye diseases. ..
Mohlin C, Sandholm K, Ekdahl K, Nilsson B. The link between morphology and complement in ocular disease. Mol Immunol. 2017;89:84-99 pubmed publisher