Experts and Doctors on lymph nodes in Switzerland

Summary

Locale: Switzerland
Topic: lymph nodes

Top Publications

  1. Kopfstein L, Veikkola T, Djonov V, Baeriswyl V, Schomber T, Strittmatter K, et al. Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis. Am J Pathol. 2007;170:1348-61 pubmed
  2. Finke D, Baribaud F, Diggelmann H, Acha Orbea H. Extrafollicular plasmablast B cells play a key role in carrying retroviral infection to peripheral organs. J Immunol. 2001;166:6266-75 pubmed
  3. Iezzi G, Scheidegger D, Lanzavecchia A. Migration and function of antigen-primed nonpolarized T lymphocytes in vivo. J Exp Med. 2001;193:987-93 pubmed
  4. Baruthio F, Quadroni M, Ruegg C, Mariotti A. Proteomic analysis of membrane rafts of melanoma cells identifies protein patterns characteristic of the tumor progression stage. Proteomics. 2008;8:4733-47 pubmed publisher
  5. Staebler S, Sydler T, Buergi E, McCullough K, McNeilly F, Allan G, et al. PMWS: an emerging disease identified in archived porcine tissues. Vet J. 2005;170:132-4 pubmed
    ..After 1989, positive pigs were found almost every year among the 20-40 cases investigated annually. These results indicate that PCV-2 has been present in Switzerland for some time, and at least since 1986. ..
  6. Stoeckli S, Haerle S, Strobel K, Haile S, Hany T, Schuknecht B. Initial staging of the neck in head and neck squamous cell carcinoma: a comparison of CT, PET/CT, and ultrasound-guided fine-needle aspiration cytology. Head Neck. 2012;34:469-76 pubmed publisher
    ..Ultrasound-guided FNAC seems to correlate best with histologic staging compared with PET/CT and CT. None of the modality is reliable enough to replace elective neck treatment in cN0 necks. ..
  7. Ballester M, Nembrini C, Dhar N, de Titta A, De Piano C, Pasquier M, et al. Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis. Vaccine. 2011;29:6959-66 pubmed publisher
    ..These findings highlight the potential of administrating NP-based formulations by the pulmonary route for TB vaccination. ..
  8. Perreau M, Savoye A, De Crignis E, Corpataux J, Cubas R, Haddad E, et al. Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production. J Exp Med. 2013;210:143-56 pubmed publisher
    ..However, only the percentage of Tfh cells correlated with the levels of plasma viremia. These results demonstrate that Tfh cells serve as the major CD4 T cell compartment for HIV infection, replication, and production. ..
  9. Suter M, Lew A, Grob P, Adema G, Ackermann M, Shortman K, et al. BAC-VAC, a novel generation of (DNA) vaccines: A bacterial artificial chromosome (BAC) containing a replication-competent, packaging-defective virus genome induces protective immunity against herpes simplex virus 1. Proc Natl Acad Sci U S A. 1999;96:12697-702 pubmed

More Information

Publications69

  1. Allenbach C, Launois P, Mueller C, Tacchini Cottier F. An essential role for transmembrane TNF in the resolution of the inflammatory lesion induced by Leishmania major infection. Eur J Immunol. 2008;38:720-31 pubmed publisher
    ..major, enabling the regulation of inflammation, and the optimal killing of Leishmania parasites at the site of infection. ..
  2. Zlobec I, Hadrich M, Dawson H, Koelzer V, Borner M, Mallaev M, et al. Intratumoural budding (ITB) in preoperative biopsies predicts the presence of lymph node and distant metastases in colon and rectal cancer patients. Br J Cancer. 2014;110:1008-13 pubmed publisher
    ..Tumour budding can be assessed in the preoperative biopsy of CRC patients. It is practical, reproducible and predictive of LN and distant metastasis. Intratumoural budding qualifies for further investigation in the prospective setting. ..
  3. Beil Wagner J, Dössinger G, Schober K, Vom Berg J, Tresch A, Grandl M, et al. T cell-specific inactivation of mouse CD2 by CRISPR/Cas9. Sci Rep. 2016;6:21377 pubmed publisher
    ..6% were not expressing CD2, respectively. T cells lacking CD2 carryied mutations, which confirmed that Cas9 driven by cell-type specific promoters can edit genes in the mouse and may thus allow targeted studies of gene function in vivo. ..
  4. Barekati Z, Radpour R, Lu Q, Bitzer J, Zheng H, Toniolo P, et al. Methylation signature of lymph node metastases in breast cancer patients. BMC Cancer. 2012;12:244 pubmed publisher
    ..The contribution of aberrant methylation alterations of BMP6, BRCA1 and P16 genes in lymph node metastasis might provide a further clue to establish useful biomarkers for screening metastasis. ..
  5. Ghadjar P, Simcock M, Schreiber Facklam H, Zimmer Y, Gräter R, Evers C, et al. Incidence of small lymph node metastases with evidence of extracapsular extension: clinical implications in patients with head and neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2010;78:1366-72 pubmed publisher
    ..03, 95% CI: 1.1-5.8). The incidence of small ECE positive LN metastases is a significant prognostic factor in HNSCC patients. Small ECE positive LN may represent more invasive tumor biology and could be used as prognostic markers. ..
  6. Brinkmann V, Lynch K. FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity. Curr Opin Immunol. 2002;14:569-75 pubmed
    ..Stimulation of sphingosine 1-phosphate receptors leads to sequestration of lymphocytes in secondary lymphatic tissues and thus away from inflammatory lesions and graft sites. ..
  7. Johann S, Klaeser B, Krause T, Mueller M. Comparison of outcome and recurrence-free survival after sentinel lymph node biopsy and lymphadenectomy in vulvar cancer. Gynecol Oncol. 2008;110:324-8 pubmed publisher
    ..SLNB in vulvar cancer seems to be a safe alternative to ILND in order to reduce morbidity of surgical treatment. ..
  8. Eppenberger U, Kueng W, Schlaeppi J, Roesel J, Benz C, Mueller H, et al. Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients. J Clin Oncol. 1998;16:3129-36 pubmed
    ..Separate primary and validating clinical studies concur that tumor VEGF level is the most important prognostic parameter among several markers of tumor angiogenesis and proteolysis. ..
  9. Thurlimann B, Price K, Gelber R, Holmberg S, Crivellari D, Colleoni M, et al. Is chemotherapy necessary for premenopausal women with lower-risk node-positive, endocrine responsive breast cancer? 10-year update of International Breast Cancer Study Group Trial 11-93. Breast Cancer Res Treat. 2009;113:137-44 pubmed publisher
    ..A large trial is needed to determine whether chemotherapy adds benefit to endocrine therapy for this population. ..
  10. Reddy S, Swartz M, Hubbell J. Targeting dendritic cells with biomaterials: developing the next generation of vaccines. Trends Immunol. 2006;27:573-9 pubmed
    ..Here, we review the latest advances in biomaterial drug vehicles, such as polymer microparticles and nanoparticles, and liposomes, that are being used to target DCs in new strategies for vaccination. ..
  11. Weixler B, Warschkow R, Güller U, Zettl A, von Holzen U, Schmied B, et al. Isolated tumor cells in stage I & II colon cancer patients are associated with significantly worse disease-free and overall survival. BMC Cancer. 2016;16:106 pubmed publisher
    ..Based on these data, the presence of ITC should be classified as a high risk factor in stage I & II colon cancer patients who might benefit from adjuvant chemotherapy. ..
  12. Rochford E, Sabaté Brescó M, Zeiter S, Kluge K, Poulsson A, Ziegler M, et al. Monitoring immune responses in a mouse model of fracture fixation with and without Staphylococcus aureus osteomyelitis. Bone. 2016;83:82-92 pubmed publisher
    ..A divergent local immune polarization is evident in the infected versus non-infected animals, with the immune response ultimately unable to clear the S. aureus infection. ..
  13. Tshering Vogel D, Thoeny H. Cross-sectional imaging in cancers of the head and neck: how we review and report. Cancer Imaging. 2016;16:20 pubmed publisher
    ..Knowledge of these pitfalls can help to avoid misinterpretation. The important points to be mentioned while reporting are also enumerated. ..
  14. Reubi J, Läderach U, Waser B, Gebbers J, Robberecht P, Laissue J. Vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor subtypes in human tumors and their tissues of origin. Cancer Res. 2000;60:3105-12 pubmed
  15. Beneder C, Fuechsel F, Krause T, Kuhn A, Mueller M. The role of 3D fusion imaging in sentinel lymphadenectomy for vulvar cancer. Gynecol Oncol. 2008;109:76-80 pubmed publisher
    ..Fusion imaging using SPECT and CT/MRI can detect SLN in vulvar cancer more precisely than planar imaging regarding number and anatomical localisation. FICT revealed additional information in seven out of ten cases (70%). ..
  16. Brandes M, Willimann K, Lang A, Nam K, Jin C, Brenner M, et al. Flexible migration program regulates gamma delta T-cell involvement in humoral immunity. Blood. 2003;102:3693-701 pubmed
    ..Collectively, our findings agree with a role for gamma delta T cells in humoral immunity during the early phase of antimicrobial responses. ..
  17. Link A, Vogt T, Favre S, Britschgi M, Acha Orbea H, Hinz B, et al. Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells. Nat Immunol. 2007;8:1255-65 pubmed
    ..Our data suggest that lymph nodes and T zone fibroblastic reticular cells have a key function in naive CD4(+) and CD8(+) T cell homeostasis by providing a limited reservoir of survival factors. ..
  18. Jurisic G, Detmar M. Lymphatic endothelium in health and disease. Cell Tissue Res. 2009;335:97-108 pubmed publisher
    ..The emerging role of lymphatic endothelium in the context of inflammation indicates that therapeutics targeting the lymphatic vasculature might represent a new strategy for anti-inflammatory therapies...
  19. Chaignat V, Worwa G, Scherrer N, Hilbe M, Ehrensperger F, Batten C, et al. Toggenburg Orbivirus, a new bluetongue virus: initial detection, first observations in field and experimental infection of goats and sheep. Vet Microbiol. 2009;138:11-9 pubmed publisher
    ..In small ruminants, TOV leads to mild bluetongue-like symptoms. Further investigations about prevalence of this virus are needed to increase the knowledge on its epidemiology...
  20. Murer K, Huber G, Haile S, Stoeckli S. Comparison of morbidity between sentinel node biopsy and elective neck dissection for treatment of the n0 neck in patients with oral squamous cell carcinoma. Head Neck. 2011;33:1260-4 pubmed publisher
    ..This supports our opinion that patients with nodal negative early SCC of the oral cavity should be offered SNB. ..
  21. Cervantes Barragan L, Firner S, Bechmann I, Waisman A, Lahl K, Sparwasser T, et al. Regulatory T cells selectively preserve immune privilege of self-antigens during viral central nervous system infection. J Immunol. 2012;188:3678-85 pubmed publisher
    ..Taken together, these results suggest that Tregs preserve CNS immune privilege through selective control of CNS-specific Th cells while keeping protective antiviral immunity fully operative. ..
  22. Waldvogel A, Zakher A, Guionaud C, Fernandez P, Heussler V. Regulation of bovine IL-12R beta 2 subunit mRNA expression in bovine lymph node cells. Gene. 2002;289:61-7 pubmed
    ..Furthermore, cells with upregulated boIL-12R beta 2 mRNA responded with enhanced expression of interferon gamma to treatment with interleukin 12. ..
  23. Vacheron S, Luther S, Acha Orbea H. Preferential infection of immature dendritic cells and B cells by mouse mammary tumor virus. J Immunol. 2002;168:3470-6 pubmed
    ..These results highlight the importance of professional APC and efficient T cell priming for the establishment of a persistent infection by mouse mammary tumor virus...
  24. Banfi B, Molnar G, Maturana A, Steger K, Hegedus B, Demaurex N, et al. A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes. J Biol Chem. 2001;276:37594-601 pubmed
    ..NOX5 is likely to be involved in Ca(2+)-activated, redox-dependent processes of spermatozoa and lymphocytes such as sperm-oocyte fusion, cell proliferation, and cytokine secretion. ..
  25. Chai Q, Onder L, Scandella E, Gil Cruz C, Perez Shibayama C, Cupovic J, et al. Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity. 2013;38:1013-24 pubmed publisher
    ..Thus, myofibroblasic FRC precursors are able to generate the basic T cell zone infrastructure, whereas LT?R-dependent maturation of FRCs guarantees full immunocompetence and hence optimal LN function during infection. ..
  26. Young A, Seabrook T, Marston W, Dudler L, Hay J. A role for lymphatic endothelium in the sequestration of recirculating gamma delta T cells in TNF-alpha-stimulated lymph nodes. Eur J Immunol. 2000;30:327-34 pubmed
  27. Peitsch M, Polzar B, Stephan H, Crompton T, MacDonald H, Mannherz H, et al. Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J. 1993;12:371-7 pubmed
    ..We propose that during apoptosis, an endonuclease indistinguishable from DNase I gains access to the nucleus due to the breakdown of the ER and the nuclear membrane. ..
  28. Allegrini P, Wachsmuth E. Course of murine leukemia retrovirus infection determined in vivo by magnetic resonance imaging. Lab Invest. 1990;63:568-75 pubmed
    ..Thus, statistically relevant results can be obtained in an infection model requiring the use of only a few animals...
  29. Montecino Rodriguez E, Loor F. Haematopoietic cell transfers between C57BL/6 mice differing at the lpr or gld locus. Immunology. 1991;74:127-31 pubmed
    ..The [lpr----gld] chimaeras developed a lymphoid aplasia (as in the [lpr----wild] chimaeras). This result shows that the gld environment cannot substitute for the lpr environment and allow for the emergence of an lpr-induced pathology. ..
  30. Onder L, Narang P, Scandella E, Chai Q, Iolyeva M, Hoorweg K, et al. IL-7-producing stromal cells are critical for lymph node remodeling. Blood. 2012;120:4675-83 pubmed publisher
    ..Taken together, this study identifies LN LECs as a major source of IL-7 and shows that IL-7-producing stromal cells are critical for reconstruction and remodeling of the distinct LN microenvironment. ..
  31. Link A, Hardie D, Favre S, Britschgi M, Adams D, Sixt M, et al. Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans. Am J Pathol. 2011;178:1662-75 pubmed publisher
    ..In conclusion, TRCs and conduits are hallmarks of secondary lymphoid organs and of well-developed TLTs, in both mice and humans, and are likely to act as important scaffold and organizer cells of the T-cell-rich zone. ..
  32. Haerle S, Strobel K, Ahmad N, Soltermann A, Schmid D, Stoeckli S. Contrast-enhanced ¹?F-FDG-PET/CT for the assessment of necrotic lymph node metastases. Head Neck. 2011;33:324-9 pubmed publisher
    ..Therefore, in patients scheduled for ¹?F-FDG-PET/CT, we strongly suggest performing a contrast-enhanced ¹?F-FDG-PET/CT, which is not routine in most centers. ..
  33. Iolyeva M, Karaman S, Willrodt A, Weingartner S, Vigl B, Halin C. Novel role for ALCAM in lymphatic network formation and function. FASEB J. 2013;27:978-90 pubmed publisher
    ..Moreover, DC migration from lung to draining lymph nodes was compromised in ALCAM mice. Collectively, our data reveal a novel role for ALCAM in stabilizing LEC-LEC interactions and in the organization and function of the LV network. ..
  34. Mikulic J, Bioley G, Corthesy B. SIgA-Shigella Immune Complexes Interact with Dectin-1 and SIGNR3 to Differentially Regulate Mouse Peyer's Patch and Mesenteric Lymph Node Dendritic Cell's Responsiveness. J Mol Biol. 2017;429:2387-2400 pubmed publisher
  35. Guarda G, Hons M, Soriano S, Huang A, Polley R, MartIn Fontecha A, et al. L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells. Nat Immunol. 2007;8:743-52 pubmed
    ..The inducible recruitment of blood-borne effector and memory T cells to lymph nodes may represent a mechanism for terminating primary and limiting secondary immune responses. ..
  36. Groettrup M, von Boehmer H. T cell receptor beta chain dimers on immature thymocytes from normal mice. Eur J Immunol. 1993;23:1393-6 pubmed
    ..Our results show for the first time that under physiological conditions a TCR beta dimer can be expressed on the cell surface without the TCR alpha chain. ..
  37. MartIn Fontecha A, Sebastiani S, Höpken U, Uguccioni M, Lipp M, Lanzavecchia A, et al. Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med. 2003;198:615-21 pubmed
    ..These results indicate that DC number and tissue inflammation are critical parameters for DC-based vaccination. ..
  38. Onder L, Mörbe U, Pikor N, Novković M, Cheng H, Hehlgans T, et al. Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity. 2017;47:80-92.e4 pubmed publisher
    ..Finally, the finding that pharmacologically enforced interaction between LTi cells and LECs promotes ectopic LN formation underscores the central LTo function of LECs. ..
  39. Fluck M, Zurcher G, Andres A, Ziemiecki A. Molecular characterization of the murine syk protein tyrosine kinase cDNA, transcripts and protein. Biochem Biophys Res Commun. 1995;213:273-81 pubmed
    ..Upregulated expression of syk was observed in aggressive, metastasizing mammary gland tumours but not in well differentiated, non-metastasizing tumors. ..
  40. Brocker T. Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells. J Exp Med. 1997;186:1223-32 pubmed
  41. Walter R, Bachmann S, Schaffner A, Ruegg R, Schoedon G. Bone marrow involvement in Whipple's disease: rarely reported, but really rare?. Br J Haematol. 2001;112:677-9 pubmed
  42. Prinz M, Montrasio F, Klein M, Schwarz P, Priller J, Odermatt B, et al. Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proc Natl Acad Sci U S A. 2002;99:919-24 pubmed
    ..Macrophage subsets are plausible candidates for lymphoreticular prion pathogenesis and neuroinvasion in the absence of FDCs, and may represent a novel target for postexposure prophylaxis. ..
  43. Ruedl C, Storni T, Lechner F, Bächi T, Bachmann M. Cross-presentation of virus-like particles by skin-derived CD8(-) dendritic cells: a dispensable role for TAP. Eur J Immunol. 2002;32:818-25 pubmed
    ..In summary, the results show that VLP-derived epitopes are cross-presented by CD8(-) DC in vivo in a partial TAP-independent fashion and highlight important differences in the processing machinery of DC versus macrophages...
  44. Went P, Ascani S, Strøm E, Brorson S, Musso M, Zinzani P, et al. Nodal marginal-zone lymphoma associated with monoclonal light-chain and heavy-chain deposition disease. Lancet Oncol. 2004;5:381-3 pubmed
  45. Seiler R, von Gunten M, Thalmann G, Fleischmann A. High CD10 expression predicts favorable outcome in surgically treated lymph node-positive bladder cancer patients. Hum Pathol. 2012;43:269-75 pubmed publisher
    ..The favorable outcome in bladder cancer patients with high CD10 expression might suggest a tumor suppressive function of CD10. ..
  46. Kisielow J, Kopf M, Karjalainen K. SCART scavenger receptors identify a novel subset of adult gammadelta T cells. J Immunol. 2008;181:1710-6 pubmed
    ..Characterization of SCART2 positive immature and peripheral gammadelta T cells suggests that they undergo lineage specification in the thymus and belong to a new IL-17-producing subset with distinct homing capabilities. ..
  47. Britschgi M, Favre S, Luther S. CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19. Eur J Immunol. 2010;40:1266-71 pubmed publisher
    ..Our findings suggest that CCL21 is the critical CCR7 ligand regulating DC homeostasis and function in vivo with CCL19 being redundant for these processes. ..
  48. Macpherson A, Uhr T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science. 2004;303:1662-5 pubmed
  49. Chakour R, Guler R, Bugnon M, Allenbach C, Garcia I, Mauel J, et al. Both the Fas ligand and inducible nitric oxide synthase are needed for control of parasite replication within lesions in mice infected with Leishmania major whereas the contribution of tumor necrosis factor is minimal. Infect Immun. 2003;71:5287-95 pubmed
    ..Thus, IFN-gamma, FasL, and iNOS appear to be essential for the complete control of parasite replication, while the contribution of TNF is more important in controlling inflammation at the site of parasite inoculation. ..
  50. Heer A, Harris N, Kopf M, Marsland B. CD4+ and CD8+ T cells exhibit differential requirements for CCR7-mediated antigen transport during influenza infection. J Immunol. 2008;181:6984-94 pubmed
    ..Overall, our data show that CCR7-mediated active Ag transport is differentially required for CD4(+) and CD8(+) T cell expansion during influenza infection. ..
  51. Schobesberger M, Summerfield A, Doherr M, Zurbriggen A, Griot C. Canine distemper virus-induced depletion of uninfected lymphocytes is associated with apoptosis. Vet Immunol Immunopathol. 2005;104:33-44 pubmed
  52. Bucher P, Gervaz P, Morel P. Long-term results of radical resection for locally advanced duodenal adenocarcinoma. Hepatogastroenterology. 2005;52:1727-9 pubmed
    ..Duodenal adenocarcinomas are uncommon tumors characterized by non-specific symptoms and late diagnosis. The objective of this study was to assess long-term results of locally advanced duodenal adenocarcinoma treated by surgical resection...
  53. Nombela Arrieta C, Mempel T, Soriano S, Mazo I, Wymann M, Hirsch E, et al. A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress. J Exp Med. 2007;204:497-510 pubmed
    ..In summary, our data support a central role for DOCK2, and to a lesser extent T cell-expressed PI3Kgamma, for signal transduction during interstitial lymphocyte migration and S1P-mediated egress. ..
  54. Thomas S, Vokali E, Lund A, Hubbell J, Swartz M. Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response. Biomaterials. 2014;35:814-24 pubmed publisher
    ..Together, these data implicate the TDLN as a delivery target for adjuvant therapy of solid tumors. ..
  55. Peitsch M, Hesterkamp T, Polzar B, Mannherz H, Tschopp J. Functional characterisation of serum DNase I in MRL-lpr/lpr mice. Biochem Biophys Res Commun. 1992;186:739-45 pubmed
    ..Furthermore, we show that this "apoptosis-ladder" can be obtained with purified DNase I in presence of normal serum. ..
  56. Yang C, Vogt T, Favre S, Scarpellino L, Huang H, Tacchini Cottier F, et al. Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes. Proc Natl Acad Sci U S A. 2014;111:E109-18 pubmed publisher
    ..Thus, this study documents the surprising plasticity as well as the complex regulation of FRC networks allowing the rapid LN hyperplasia that is critical for mounting efficient adaptive immunity. ..
  57. Ohteki T, MacDonald H. Stringent V beta requirement for the development of NK1.1+ T cell receptor-alpha/beta+ cells in mouse liver. J Exp Med. 1996;183:1277-82 pubmed
    ..Collectively, our data indicate that liver NK1+T cells have a stringent requirement for expression of TCR-Vbeta8.2, Vbeta7, or Vbeta2 for their development. ..
  58. Mbow M, Rutti B, Brossard M. IFN-gamma IL-2, and IL-4 mRNA expression in the skin and draining lymph nodes of BALB/c mice repeatedly infested with nymphal Ixodes ricinus ticks. Cell Immunol. 1994;156:254-61 pubmed
    ..Notably, the cytokine pattern observed in the skin and draining lymph nodes is not associated with a protective immune response in mice against I. ricinus nymphal ticks infestations. ..
  59. Merino R, Fossati L, Iwamoto M, Takahashi S, Lemoine R, Ibnou Zekri N, et al. Effect of long-term anti-CD4 or anti-CD8 treatment on the development of lpr CD4- CD8- double negative T cells and of the autoimmune syndrome in MRL-lpr/lpr mice. J Autoimmun. 1995;8:33-45 pubmed
    ..Our results support the idea that CD8+ T cells are a major source of the lpr DN T cells, and that the lpr DN T cells play a minor, if any, role in the pathogenesis of lupus-like autoimmune syndrome in MRL-lpr/lpr mice. ..
  60. Zanolari P, Robert N, Lyashchenko K, Pfyffer G, Greenwald R, Esfandiari J, et al. Tuberculosis caused by Mycobacterium microti in South American camelids. J Vet Intern Med. 2009;23:1266-72 pubmed publisher
    ..Because cases of M. microti infection have been reported in immunocompromized human patients, the zoonotic potential of the organism should be kept in mind when dealing with this disease in SAC. ..