Genomes and Genes
Experts and Doctors on lipid bilayers in France
Topic: lipid bilayers
- Le Guillou J, Ropers M, Gaillard C, David Briand E, van Leeuwen Ibarrola J, Desherces S, et al. Sequestration of bovine seminal plasma proteins by different assemblies of phosphatidylcholine: A new technical approach. Colloids Surf B Biointerfaces. 2016;140:523-530 pubmed publisher..The difference between the two sequestering agents lies on their surface properties: LDL have a strong tendency to merge with the outer layer whereas liposomes mainly remain in the bulk on the same time scale. ..
- Dennison A, Jones R, Staniforth R, Parnell A. Interaction of partially denatured insulin with a DSPC floating lipid bilayer. Soft Matter. 2016;12:824-9 pubmed publisher..We propose that the perturbation of the membrane by misfolded proteins involves long term occupation of the membrane by these proteins, rather than transient perforation events. ..
- Marquette A, Lorber B, Bechinger B. Reversible liposome association induced by LAH4: a peptide with potent antimicrobial and nucleic acid transfection activities. Biophys J. 2010;98:2544-53 pubmed publisher..Our finding that peptides are essential for vesicle aggregation contributes to a better understanding of the activity of antimicrobial peptides, and suggests an additional layer of complexity in membrane-protein lipid interactions. ..
- Casciola M, Kasimova M, Rems L, Zullino S, Apollonio F, Tarek M. Properties of lipid electropores I: Molecular dynamics simulations of stabilized pores by constant charge imbalance. Bioelectrochemistry. 2016;109:108-16 pubmed publisher..We further extend these studies in a follow-up paper (Rems et al., Bioelectrochemistry, Submitted), by proposing an improved continuum model of pore conductance consistent with the results from the MD simulations. ..
- ..2008) and Pucadyil and Schmid (2008) unexpectedly shows that helix disassembly is also necessary for membrane fission. ..
- Guo Y, Baulin V, Thalmann F. Peroxidised phospholipid bilayers: insight from coarse-grained molecular dynamics simulations. Soft Matter. 2016;12:263-71 pubmed publisher..Soft Matter, 2014, 10, 4241]. Predictions for the mechanical properties, membrane thickness and lateral distribution of hydroperoxide groups in the phospholipid bilayer are presented. ..
- Pincet F, Le Bouar T, Zhang Y, Esnault J, Mallet J, Perez E, et al. Ultraweak sugar-sugar interactions for transient cell adhesion. Biophys J. 2001;80:1354-8 pubmed..This adhesion is ultralow and therefore difficult to measure. Such small interactions explain why the concept of specific interactions between carbohydrates is often neglected. ..
- Mojzisova H, Bonneau S, Maillard P, Berg K, Brault D. Photosensitizing properties of chlorins in solution and in membrane-mimicking systems. Photochem Photobiol Sci. 2009;8:778-87 pubmed publisher..The charged chlorins, in particular TPCS(2a), are the most efficient, a result discussed in relation with the technology of photochemical internalization, PCI. ..
- Kasimova M, Tarek M, Shaytan A, Shaitan K, Delemotte L. Voltage-gated ion channel modulation by lipids: insights from molecular dynamics simulations. Biochim Biophys Acta. 2014;1838:1322-31 pubmed publisher..For the latter, however, it is shown that local interactions between the ion channel and the lipid headgroups are key-elements of the modulation. ..
- Saccani J, Castano S, Desbat B, Blaudez D. A phospholipid bilayer supported under a polymerized Langmuir film. Biophys J. 2003;85:3781-7 pubmed
- Scomparin C, Lecuyer S, Ferreira M, Charitat T, Tinland B. Diffusion in supported lipid bilayers: influence of substrate and preparation technique on the internal dynamics. Eur Phys J E Soft Matter. 2009;28:211-20 pubmed publisher..Preparing bilayers from vesicle fusion in same conditions leads to more random behaviours and shifted transition temperatures. ..
- Korchowiec B, Gorczyca M, Rogalska E, Regnouf de Vains J, Mourer M, Korchowiec J. The selective interactions of cationic tetra-p-guanidinoethylcalixarene with lipid membranes: theoretical and experimental model studies. Soft Matter. 2016;12:181-90 pubmed publisher..The latter effect, which is possible due to a flip-flop inversion of the CX1 orientation in the lipid layer compared to the aqueous phase, may be responsible for its antibacterial activity. ..
- Chipot C, Tarek M. Interaction of a peptide nanotube with a water-membrane interface. Phys Biol. 2006;3:S20-5 pubmed..The latter opens new questions about how peptide nanotubes permeate the membrane, in particular whether or not (i) self-assembly precedes partitioning and (ii) translocation occurs with the complete tubular structure. ..
- Cognasse F, Hamzeh Cognasse H, Laradi S, Chou M, Seghatchian J, Burnouf T, et al. The role of microparticles in inflammation and transfusion: A concise review. Transfus Apher Sci. 2015;53:159-67 pubmed publisher..Microparticles originating from platelets, leukocytes, erythrocytes, and endothelial cells are associated with a variety of pathophysiological conditions. This review summarises the role of Microparticles in modulating inflammation. ..
- Grauby Heywang C, Turlet J. Study of the interaction of beta-cyclodextrin with phospholipid monolayers by surface pressure measurements and fluorescence microscopy. J Colloid Interface Sci. 2008;322:73-8 pubmed publisher..Images show that SM monolayers are more homogeneous after beta-CD injection, because of the lipid desorption. At last, it seems that lipid desorption occurs only in a restricted surface pressure range, depending on the lipid. ..
- Seantier B, Breffa C, Felix O, Decher G. Dissipation-enhanced quartz crystal microbalance studies on the experimental parameters controlling the formation of supported lipid bilayers. J Phys Chem B. 2005;109:21755-65 pubmed..As expected, the physical state of the membrane controls the interaction with both surface and neighboring vesicles. ..
- Largueze J, Kirat K, Morandat S. Preparation of an electrochemical biosensor based on lipid membranes in nanoporous alumina. Colloids Surf B Biointerfaces. 2010;79:33-40 pubmed publisher..This sensing system was efficient to detect the alterations of lipid membranes that are induced by the addition of a commonly used non-ionic detergent: Triton X-100. ..
- Burnouf T, Chou M, Goubran H, Cognasse F, Garraud O, Seghatchian J. An overview of the role of microparticles/microvesicles in blood components: Are they clinically beneficial or harmful?. Transfus Apher Sci. 2015;53:137-45 pubmed publisher..This review focuses on the role of MPs as an essential laboratory tool and as a most effective player in transfusion science and medicine and in health and disease. ..
- Morandat S, El Kirat K. Membrane resistance to Triton X-100 explored by real-time atomic force microscopy. Langmuir. 2006;22:5786-91 pubmed..We are convinced that this approach will provide a key system to elucidate the physical mechanisms of membrane solubilization by nonionic detergents...
- Racap J, Belbahri L, Engelhardt S, Lacombe B, Lee J, Lochman J, et al. Ca2+-dependent lipid binding and membrane integration of PopA, a harpin-like elicitor of the hypersensitive response in tobacco. Mol Microbiol. 2005;58:1406-20 pubmed publisher..These characteristics suggest that PopA is part of a system that aims to attach the host cell plasma membrane and to allow molecules cross this barrier...
- M li A, Hodak H, Clantin B, Locht C, Molle G, Jacob Dubuisson F, et al. Channel properties of TpsB transporter FhaC point to two functional domains with a C-terminal protein-conducting pore. J Biol Chem. 2006;281:158-66 pubmed publisher..The N-terminal 200 residues of FhaC constitute a functionally distinct domain that modulates the pore properties and may participate in FHA recognition...
- Catel Ferreira M, Coadou G, Molle V, Mugnier P, Nordmann P, Siroy A, et al. Structure-function relationships of CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumannii. J Antimicrob Chemother. 2011;66:2053-6 pubmed publisher..The aim of this study was to determine whether this porin may be a diffusion pathway for carbapenems in A. baumannii...
- Scheuring S, Levy D, Rigaud J. Watching the components of photosynthetic bacterial membranes and their in situ organisation by atomic force microscopy. Biochim Biophys Acta. 2005;1712:109-27 pubmed
- Lata S, Schoehn G, Jain A, Pires R, Piehler J, Gottlinger H, et al. Helical structures of ESCRT-III are disassembled by VPS4. Science. 2008;321:1354-7 pubmed publisher..Such helical CHMP structures could thus assemble within the neck of an inwardly budding vesicle, catalyzing late steps in budding under the control of VPS4. ..
- Méré J, Chahinian A, Maciver S, Fattoum A, Bettache N, Benyamin Y, et al. Gelsolin binds to polyphosphoinositide-free lipid vesicles and simultaneously to actin microfilaments. Biochem J. 2005;386:47-56 pubmed..We also report that vesicle-bound gelsolin is capable of binding to actin filaments, presumably through barbed end capping. Gelsolin bound to vesicles can nucleate actin assembly, but is less active in severing microfilaments. ..
- Drin G, Cottin S, Blanc E, Rees A, Temsamani J. Studies on the internalization mechanism of cationic cell-penetrating peptides. J Biol Chem. 2003;278:31192-201 pubmed..Altogether, our results suggest that SynB and pAntp-(43-58) peptides penetrate into cells by an adsorptive-mediated endocytosis process rather than temperature-independent translocation. ..
- Li Q, Chevalier C, Henry C, Richard C, Moudjou M, Vidic J. Shadoo binds lipid membranes and undergoes aggregation and fibrillization. Biochem Biophys Res Commun. 2013;438:519-25 pubmed publisher..In consequence, the role of Sho in prion diseases might depend on the oligomerization state of Sho but also the nature of these lipoprotein assembles. ..
- Sanmartí Espinal M, Galve R, Iavicoli P, Persuy M, Pajot Augy E, Marco M, et al. Immunochemical strategy for quantification of G-coupled olfactory receptor proteins on natural nanovesicles. Colloids Surf B Biointerfaces. 2016;139:269-76 pubmed publisher..The reported method opens the possibility to develop well-characterized drug-screening platforms based on G-coupled proteins embedded on membranes. ..
- Azouzi S, Santuz H, Morandat S, Pereira C, CÃ´tÃ© F, Hermine O, et al. Antioxidant and Membrane Binding Properties of Serotonin Protect Lipids from Oxidation. Biophys J. 2017;112:1863-1873 pubmed publisher..Taken together, our results identify 5-HT as a potent inhibitor of lipid peroxidation and offer a different perspective on the role of this pleiotropic molecule. ..
- Charbit A, Andersen C, Wang J, Schiffler B, Michel V, Benz R, et al. In vivo and in vitro studies of transmembrane beta-strand deletion, insertion or substitution mutants of the Escherichia coli K-12 maltoporin. Mol Microbiol. 2000;35:777-90 pubmed..coli LamB protein comprising strands beta13 to beta16. This resulted in a protein expected to have 20 beta-strands and which completely lost all LamB-specific activities in vivo and in vitro. ..
- Legardinier S, Raguénès Nicol C, Tascon C, Rocher C, Hardy S, Hubert J, et al. Mapping of the lipid-binding and stability properties of the central rod domain of human dystrophin. J Mol Biol. 2009;389:546-58 pubmed publisher..These lipid-binding domains should thus maintain a structural link between cytoskeletal actin and sarcolemma via the membrane phospholipids. ..
- Maniti O, Cheniour M, Lecompte M, Marcillat O, Buchet R, Vial C, et al. Acyl chain composition determines cardiolipin clustering induced by mitochondrial creatine kinase binding to monolayers. Biochim Biophys Acta. 2011;1808:1129-39 pubmed publisher..The binding mechanism implicated the insertion of protein segments into monolayers, as evidenced from alternative current polarography, regardless of the chain unsaturation for the phosphatidylglycerols and cardiolipins tested. ..
- Vanni S, Vamparys L, Gautier R, Drin G, Etchebest C, Fuchs P, et al. Amphipathic lipid packing sensor motifs: probing bilayer defects with hydrophobic residues. Biophys J. 2013;104:575-84 pubmed publisher..We propose that the hypersensitivity of ALPS motifs to lipid packing defects results from the repetitive use of hydrophobic insertions along the monotonous ALPS sequence. ..
- Veneziano R, Rossi C, Chenal A, Devoisselle J, Ladant D, Chopineau J. Bordetella pertussis adenylate cyclase toxin translocation across a tethered lipid bilayer. Proc Natl Acad Sci U S A. 2013;110:20473-8 pubmed publisher..This study's in vitro demonstration of toxin translocation across a tBLM provides an opportunity to explore the molecular mechanisms of protein translocation across biological membranes in precisely defined experimental conditions...
- Fribourg P, Chami M, Sorzano C, Gubellini F, Marabini R, Marco S, et al. 3D cryo-electron reconstruction of BmrA, a bacterial multidrug ABC transporter in an inward-facing conformation and in a lipidic environment. J Mol Biol. 2014;426:2059-69 pubmed publisher..Overall, the data are consistent with a mechanism of drug transport involving large conformational changes of BmrA and show that a bacterial ABC exporter can adopt at least two open inward conformations in lipid membrane...
- Deslandes F, Thiam A, Foret L. Lipid Droplets Can Spontaneously Bud Off from a Symmetric Bilayer. Biophys J. 2017;113:15-18 pubmed publisher..This spontaneous budding mechanism gives key insights on cellular LD formation. ..
- Berrier C, Guilvout I, Bayan N, Park K, Mesneau A, Chami M, et al. Coupled cell-free synthesis and lipid vesicle insertion of a functional oligomeric channel MscL MscL does not need the insertase YidC for insertion in vitro. Biochim Biophys Acta. 2011;1808:41-6 pubmed publisher..Our results also question the real role of insertases such as YidC for membrane protein insertion in vivo. ..
- Makky A, Michel J, Maillard P, Rosilio V. Biomimetic liposomes and planar supported bilayers for the assessment of glycodendrimeric porphyrins interaction with an immobilized lectin. Biochim Biophys Acta. 2011;1808:656-66 pubmed publisher..Only mannosylated porphyrins interacted significantly with the membrane model. The methodology used proved to be efficient for the selection of potentially active compounds. ..
- Bredin J, Saint N, Malléa M, Dé E, Molle G, Pages J, et al. Alteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 region. Biochem J. 2002;363:521-8 pubmed..These results suggest that the Lys-16 residue plays an important role in the process of diffusion through the OmpF lumen. ..
- Hauet N, Artzner F, Boucher F, Grabielle Madelmont C, Cloutier I, Keller G, et al. Interaction between artificial membranes and enflurane, a general volatile anesthetic: DPPC-enflurane interaction. Biophys J. 2003;84:3123-37 pubmed..All the results taken together allowed to draw a pseudo-binary phase diagram of enflurane-dipalmitoylphosphatidylcholine in excess water. ..
- Bornet C, Saint N, Fetnaci L, Dupont M, Davin Regli A, Bollet C, et al. Omp35, a new Enterobacter aerogenes porin involved in selective susceptibility to cephalosporins. Antimicrob Agents Chemother. 2004;48:2153-8 pubmed
- Vernoux N, Maniti O, Marcillat O, Vial C, Granjon T. Mitochondrial creatine kinase interaction with heterogeneous monolayers: Effect on lipid lateral organization. Biochimie. 2009;91:752-64 pubmed publisher..Conversely these proteins may help to organize charged phospholipid domains in a membrane. ..
- Kouzayha A, Besson F. GPI-alkaline phosphatase insertion into phosphatidylcholine monolayers: phase behavior and morphology changes. Biochem Biophys Res Commun. 2005;333:1315-21 pubmed..e., pressure/area diagrams) indicates that GPI-BIAP interacted differently with DPPC and POPC monolayers. BAM images, acquired in order to visualize the interface organization induced by GPI-BIAP incorporation, confirm these differences. ..
- Haubertin D, Madaoui H, Sanson A, Guerois R, Orlowski S. Molecular dynamics simulations of E. coli MsbA transmembrane domain: formation of a semipore structure. Biophys J. 2006;91:2517-31 pubmed..Hence, comparison of molecular dynamics simulation and phylogenetic data appears as a powerful approach to investigate the functional relevance of molecular events occurring during simulations...
- Sallmann F, Baveye Descamps S, Pattus F, Salmon V, Branza N, Spik G, et al. Porins OmpC and PhoE of Escherichia coli as specific cell-surface targets of human lactoferrin. Binding characteristics and biological effects. J Biol Chem. 1999;274:16107-14 pubmed..These data support the proposal that the antibacterial activity of lactoferrin may depend, at least in part, on its ability to bind to porins, thus modifying the stability and/or the permeability of the bacterial outer membrane. ..
- Tareste D, Pincet F, Perez E, Rickling S, Mioskowski C, Lebeau L. Energy of hydrogen bonds probed by the adhesion of functionalized lipid layers. Biophys J. 2002;83:3675-81 pubmed..5 kcal/mol. This result is in good agreement with recent experimental and theoretical studies made on protein systems showing that intramolecular hydrogen bonds make a positive contribution to protein stabilization...
- Berrier C, Park K, Abes S, Bibonne A, Betton J, Ghazi A. Cell-free synthesis of a functional ion channel in the absence of a membrane and in the presence of detergent. Biochemistry. 2004;43:12585-91 pubmed..Cell-free synthesis of membrane proteins should prove a valuable tool for the production of membrane proteins whose overexpression in heterologous systems is difficult...
- Celton Morizur S, Bordes N, Fraisier V, Tran P, Paoletti A. C-terminal anchoring of mid1p to membranes stabilizes cytokinetic ring position in early mitosis in fission yeast. Mol Cell Biol. 2004;24:10621-35 pubmed..We propose that membrane-bound oligomers of mid1p assemble recruitment "platforms" for cytokinetic ring components at the medial cortex and stabilize the ring position during its compaction. ..
- Debret G, Valadié H, Stadler A, Etchebest C. New insights of membrane environment effects on MscL channel mechanics from theoretical approaches. Proteins. 2008;71:1183-96 pubmed..coli channel, providing a closed structural intermediate en route to the open state. These results give clues for better understanding why the channel activation energy is lowered in a thinner membrane. ..
- Tr pout S, Taveau J, Benabdelhak H, Granier T, Ducruix A, Frangakis A, et al. Structure of reconstituted bacterial membrane efflux pump by cryo-electron tomography. Biochim Biophys Acta. 2010;1798:1953-60 pubmed publisher..We proposed a model of MexA-OprM taking into account features of previous models based on AcrA-AcrB-TolC and our structural results providing clues to a possible mechanism of tripartite system assembly...
- Salgado G, Vogel A, Marquant R, Feller S, Bouaziz S, Alves I. The role of membranes in the organization of HIV-1 Gag p6 and Vpr: p6 shows high affinity for membrane bilayers which substantially increases the interaction between p6 and Vpr. J Med Chem. 2009;52:7157-62 pubmed publisher..The results indicate an integration route model for Vpr into virions and may help explain why previous reports failed to detect p6 in virion core preparations. ..
- Perraki A, Cacas J, Crowet J, Lins L, Castroviejo M, German Retana S, et al. Plasma membrane localization of Solanum tuberosum remorin from group 1, homolog 3 is mediated by conformational changes in a novel C-terminal anchor and required for the restriction of potato virus X movement]. Plant Physiol. 2012;160:624-37 pubmed publisher..3 localization abolish StREM1.3 function in restricting potato virus X movement. The mechanisms described here provide new insights on the control and function of lateral segregation of plant PM. ..
- Torchut E, Bourdillon C, Laval J. Reconstitution of functional electron transfer between membrane biological elements in a two-dimensional lipidic structure at the electrode interface. Biosens Bioelectron. 1994;9:719-23 pubmed..A membrane enzyme, pyruvate oxidase from E. coli, was successfully incorporated into this artificial bilayer and was found to be able to exchange electrons with ubiquinone present in the bilayer. ..
- Constantin D, Pansu B, Impéror M, Davidson P, Ribot F. Repulsion between inorganic particles inserted within surfactant bilayers. Phys Rev Lett. 2008;101:098101 pubmed..Systematic application of this technique should lead to a better understanding of the interaction between membrane inclusions...
- Bressanelli S, Stiasny K, Allison S, Stura E, Duquerroy S, Lescar J, et al. Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation. EMBO J. 2004;23:728-38 pubmed
- Bigay J, Gounon P, Robineau S, Antonny B. Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature. Nature. 2003;426:563-6 pubmed..This leads to a model for COPI dynamics in which GTP hydrolysis in Arf1 is organized temporally and spatially according to the changes in lipid packing induced by the coat. ..
- Richter R, Him J, Tessier B, Tessier C, Brisson A. On the kinetics of adsorption and two-dimensional self-assembly of annexin A5 on supported lipid bilayers. Biophys J. 2005;89:3372-85 pubmed..We propose that the local membrane environment, as defined by the presence of DOPS, DOPC, and calcium ions, controls the adsorption and reversibility of protein binding. ..
- de Saint Jean M, Delfosse V, Douguet D, Chicanne G, Payrastre B, Bourguet W, et al. Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. J Cell Biol. 2011;195:965-78 pubmed publisher..Coupled to PI(4)P metabolism, this transport cycle would create sterol gradients. Because the residues that recognize PI(4)P are conserved in Osh4p homologues, other Osh/Orp are potential sterol/phosphoinositol phosphate exchangers. ..
- Josse D, Ebel C, Stroebel D, Fontaine A, Borges F, Echalier A, et al. Oligomeric states of the detergent-solubilized human serum paraoxonase (PON1). J Biol Chem. 2002;277:33386-97 pubmed..Changes of HDL size and shape could strongly affect the binding affinity and stability of HuPON1 and result in reduced antioxidative capacity of the lipoprotein. ..
- Clantin B, Delattre A, Rucktooa P, Saint N, M li A, Locht C, et al. Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily. Science. 2007;317:957-61 pubmed publisher..General features of the mechanism obtained here are likely to apply throughout the superfamily...
- Nowak B, Paulus M, Nase J, Salmen P, Degen P, Wirkert F, et al. Solid-Supported Lipid Multilayers under High Hydrostatic Pressure. Langmuir. 2016;32:2638-43 pubmed publisher..As is commonly known, water has an abrasive effect on lipid multilayers by the formation of vesicles. We show that increasing pressure can reverse this process so that a controlled switching between multi- and bilayers is possible. ..
- Marchal D, Pantigny J, Laval J, Moiroux J, Bourdillon C. Rate constants in two dimensions of electron transfer between pyruvate oxidase, a membrane enzyme, and ubiquinone (coenzyme Q8), its water-insoluble electron carrier. Biochemistry. 2001;40:1248-56 pubmed..The kinetic constants we found show that the activated enzyme can be efficiently regulated by the oxidation level of the quinone pool in natural membranes. ..
- Macia E, Paris S, Chabre M. Binding of the PH and polybasic C-terminal domains of ARNO to phosphoinositides and to acidic lipids. Biochemistry. 2000;39:5893-901 pubmed..Phosphorylation by protein kinase C of a serine in the C domain reduces the ionic affinity of the PH+C domain for PS, but does not affect the phosphoinositide specificity. ..
- Putzu M, Kara S, Afonin S, Grage S, Bordessa A, Chaume G, et al. Structural Behavior of the Peptaibol Harzianin HK VI in a DMPC Bilayer: Insights from MD Simulations. Biophys J. 2017;112:2602-2614 pubmed publisher..The secondary structure of HZ was characterized, and it was found to be located in the 310-helical family. The specific challenges of computer simulation of nonpolar peptides are discussed briefly. ..
- Greiner V, Shvadchak V, Fritz J, Arntz Y, Didier P, Frisch B, et al. Characterization of the mechanisms of HIV-1 Vpr(52-96) internalization in cells. Biochimie. 2011;93:1647-58 pubmed publisher..Finally, using fluorescence lifetime imaging, we found that the Vpr(52-96) peptide was stable in cells for at least 48h, probably as a consequence of the poor accessibility of the peptide to proteolytic enzymes in aggregates. ..