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Top Publications

  1. Trantham Davidson H, Kroner S, Seamans J. Dopamine modulation of prefrontal cortex interneurons occurs independently of DARPP-32. Cereb Cortex. 2008;18:951-8 pubmed
  2. Metz T, Qian W, Jacobs J, Gritsenko M, Moore R, Polpitiya A, et al. Application of proteomics in the discovery of candidate protein biomarkers in a diabetes autoantibody standardization program sample subset. J Proteome Res. 2008;7:698-707 pubmed
  3. Rasouli J, Lekhraj R, White N, Flamm E, Pilla A, Strauch B, et al. Attenuation of interleukin-1beta by pulsed electromagnetic fields after traumatic brain injury. Neurosci Lett. 2012;519:4-8 pubmed publisher
    ..These results warrant further studies to assess the effects of PEMF on other inflammatory markers and functional outcomes. ..
  4. Connor W, Lin D, Neuringer M. Biochemical markers for puberty in the monkey testis: desmosterol and docosahexaenoic acid. J Clin Endocrinol Metab. 1997;82:1911-6 pubmed
    ..These changes suggest that desmosterol and both n-3 and n-6 polyunsaturated fatty acids may have important roles in sexual maturation. ..
  5. Wang Y, Yu J. Na(+)/K(+) -ATPase as a marker for detecting pulmonary sensory receptors. Sheng Li Xue Bao. 2002;54:390-4 pubmed
    ..This technique permits examining pulmonary receptor structures in detail, and should assist in identifying the morphology of the receptors and the mechanisms of receptor activation. ..
  6. Wang Y, Yang M. The ARABIDOPSIS SKP1-LIKE1 (ASK1) protein acts predominately from leptotene to pachytene and represses homologous recombination in male meiosis. Planta. 2006;223:613-7 pubmed
    ..These results indicate that ASK1 normally plays a repressive role in male recombination in Arabidopsis. ..
  7. Breburda E, Dambaeva S, Slukvin I, Golos T. Selective distribution and pregnancy-specific expression of DC-SIGN at the maternal-fetal interface in the rhesus macaque: DC-SIGN is a putative marker of the recognition of pregnancy. Placenta. 2006;27:11-21 pubmed publisher
  8. Agca C, Ries J, Kolath S, Kim J, Forrester L, Antoniou E, et al. Luteinization of porcine preovulatory follicles leads to systematic changes in follicular gene expression. Reproduction. 2006;132:133-45 pubmed
    ..Cells within preovulatory luteinized follicles had a gene-expression profile of nonproliferative and migratory cells with angiogenic properties. Approximately, 40% of the discovered genes had unknown function. ..
  9. Hansel D, Epstein J, Berbescu E, Fine S, Young R, Cheville J. Renal carcinoid tumor: a clinicopathologic study of 21 cases. Am J Surg Pathol. 2007;31:1539-44 pubmed
    ..Of the remaining patients, 7 patients were alive without disease and 6 patients were alive with disease. Additional metastases developed in 4 patients and included metastases to the liver and bone...

More Information

Publications287 found, 100 shown here

  1. Hofer T, Marzetti E, Xu J, Seo A, Gulec S, Knutson M, et al. Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy. Exp Gerontol. 2008;43:563-70 pubmed publisher
    ..These results suggest that RNA oxidation, possibly mediated by increased non-heme iron, might contribute to muscle atrophy due to disuse particularly in aged muscle...
  2. Brown L, Brown S. Zic2 is expressed in pluripotent cells in the blastocyst and adult brain expression overlaps with makers of neurogenesis. Gene Expr Patterns. 2009;9:43-9 pubmed publisher
    ..The presence of Zic2 in pluripotent cells of the embryo as well as in dividing neural cells in the adult suggests that this transcription factor may have a role in maintaining pluripotency. ..
  3. Chen L, Xuan J, Wang C, Shih I, Wang Y, Zhang Z, et al. Knowledge-guided multi-scale independent component analysis for biomarker identification. BMC Bioinformatics. 2008;9:416 pubmed publisher
    ..More importantly, the proposed approach shows promising results to infer novel biomarkers for ovarian cancer and extend current knowledge. ..
  4. Andrew A, Mason R, Memoli V, Duell E. Arsenic activates EGFR pathway signaling in the lung. Toxicol Sci. 2009;109:350-7 pubmed publisher
    ..Further work is needed to assess the clinical utility of targeting the EGFR pathway in subgroups of lung cancer patients who have been exposed to elevated levels of arsenic. ..
  5. Floriano P, Christodoulides N, Miller C, Ebersole J, Spertus J, Rose B, et al. Use of saliva-based nano-biochip tests for acute myocardial infarction at the point of care: a feasibility study. Clin Chem. 2009;55:1530-8 pubmed publisher
    ..Complementary to ECG, saliva-based tests within lab-on-a-chip systems may provide a convenient and rapid screening method for cardiac events in prehospital stages for AMI patients. ..
  6. Haustein S, Kwun J, Fechner J, Kayaoglu A, Faure J, Roenneburg D, et al. Interleukin-15 receptor blockade in non-human primate kidney transplantation. Transplantation. 2010;89:937-44 pubmed publisher
    ..Peritransplant IL-15 receptor blockade does not prolong allograft survival in non-human primate renal transplantation; however, it reduces the number of CD8 T cells and natural killer cells in the peripheral blood. ..
  7. Kern E, Erhard P, Sun W, Genuth S, Weiss M. Early urinary markers of diabetic kidney disease: a nested case-control study from the Diabetes Control and Complications Trial (DCCT). Am J Kidney Dis. 2010;55:824-34 pubmed publisher
    ..Renal tubule stress may be more severe, reflecting abnormal renal tubule processing of AGE-modified proteins, in individuals susceptible to diabetic nephropathy. ..
  8. Afif W, Loftus E, Faubion W, Kane S, Bruining D, Hanson K, et al. Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease. Am J Gastroenterol. 2010;105:1133-9 pubmed publisher
    ..Increasing the infliximab dose in patients who have HACAs is ineffective, whereas in patients with subtherapeutic infliximab concentrations, this strategy may be a good alternative to changing to another anti-TNF agent. ..
  9. Sagomonyants K, Hakim Zargar M, Jhaveri A, Aronow M, Gronowicz G. Porous tantalum stimulates the proliferation and osteogenesis of osteoblasts from elderly female patients. J Orthop Res. 2011;29:609-16 pubmed publisher
    ..In conclusion, tantalum greatly stimulates cell proliferation, and improves the ability of HOBs from older patients to form bone...
  10. Hadker N, Garg S, Costanzo C, Miller J, Foster T, van der Helm W, et al. Financial impact of a novel pre-eclampsia diagnostic test versus standard practice: a decision-analytic modeling analysis from a UK healthcare payer perspective. J Med Econ. 2010;13:728-37 pubmed publisher
  11. Goldstein J, Kominsky D, Jacobson N, Bowers B, Regalia K, Austin G, et al. Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease. Gastroenterology. 2011;141:208-16 pubmed publisher
    ..001). These studies identify defective expression and function of CD116 as a distinguishing feature of IBD and implicate an associated defect in innate immune responses toward granulocyte-macrophage colony-stimulating factor. ..
  12. Hickson D, Burchfiel C, Liu J, Petrini M, Harrison K, White W, et al. Diabetes, impaired glucose tolerance, and metabolic biomarkers in individuals with normal glucose tolerance are inversely associated with lung function: the Jackson Heart Study. Lung. 2011;189:311-21 pubmed publisher
    ..Overall, our findings generally support the hypothesis that diabetes, IGT, and increased levels of metabolic biomarkers in individuals with NGT are inversely associated with lung function in African Americans, independent of adiposity. ..
  13. Guyatt G, Eikelboom J, Gould M, Garcia D, Crowther M, Murad M, et al. Approach to outcome measurement in the prevention of thrombosis in surgical and medical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e185S-e194S pubmed publisher
    ..All approaches have their limitations. The optimal choice of approach depends on the nature of the evidence available. ..
  14. Toth P, Thakker K, Jiang P, Padley R. Niacin extended-release/simvastatin combination therapy produces larger favorable changes in high-density lipoprotein particles than atorvastatin monotherapy. Vasc Health Risk Manag. 2012;8:39-44 pubmed publisher
    ..In addition, NER/S treatment resulted in a significant change in HDL particle size distribution from small and medium to large. ..
  15. Ahmed K, Madhavan M, Prasad A. Brain natriuretic peptide in apical ballooning syndrome (Takotsubo/stress cardiomyopathy): comparison with acute myocardial infarction. Coron Artery Dis. 2012;23:259-64 pubmed publisher
    ..4 (446.7, 3334.8) versus 97.4 (17.9, 264.7), P=0.04. BNP elevation is almost universal in ABS. Cardiac hemodynamic indices do not correlate with BNP levels. The magnitude of BNP elevation is higher in ABS compared with STEMI and NSTEMI. ..
  16. Puri R, Nissen S. The complementary roles of imaging and 'omics' for future anti-atherosclerotic drug development. Curr Pharm Des. 2013;19:5963-71 pubmed
    ..These approaches will provide an opportunity to better understand atherosclerosis, its complications and effective treatments across multiple ethnic populations worldwide. ..
  17. Roy M, Janal M, Crosby J, Donnelly R. Inflammatory biomarkers and progression of diabetic retinopathy in African Americans with type 1 diabetes. Invest Ophthalmol Vis Sci. 2013;54:5471-80 pubmed publisher
    ..In African Americans with T1DM, inflammation and endothelial dysfunction precede the development of DR, thus supporting the notion that inflammation may influence progression/incidence of disease. ..
  18. Keller K, Yang Y, Sun Y, Sykes R, Acott T, Wirtz M. Ankyrin repeat and suppressor of cytokine signaling box containing protein-10 is associated with ubiquitin-mediated degradation pathways in trabecular meshwork cells. Mol Vis. 2013;19:1639-55 pubmed
    ..Our evidence suggests that ASB10 may play a role in ubiquitin-mediated degradation pathways in TM cells. ..
  19. Yoshida K, Kondo R, Wang Q, Doerschuk C. Neutrophil cytoskeletal rearrangements during capillary sequestration in bacterial pneumonia in rats. Am J Respir Crit Care Med. 2006;174:689-98 pubmed
  20. von Castel Roberts K, Morkbak A, Nexo E, Edgemon C, Maneval D, Shuster J, et al. Holo-transcobalamin is an indicator of vitamin B-12 absorption in healthy adults with adequate vitamin B-12 status. Am J Clin Nutr. 2007;85:1057-61 pubmed
    ..Our results indicate that a vitamin B-12 absorption test based on measurement of holo-TC after administration of three 9-mug doses of vitamin B-12 should run for 24 h. ..
  21. Zakaria E, Campbell J, Peyton J, Garrison R. Postresuscitation tissue neutrophil infiltration is time-dependent and organ-specific. J Surg Res. 2007;143:119-25 pubmed
    ..Direct peritoneal resuscitation prevents the early obligatory fluid sequestration and promotes early fluid mobilization. ..
  22. Myers S, Ali M. Haemoglobin adducts as biomarkers of exposure to tobacco-related nitrosamines. Biomarkers. 2008;13:145-59 pubmed
  23. Peralta E, Brewer A, Louis S, Dunnington G. Vitamin E increases biomarkers of estrogen stimulation when taken with tamoxifen. J Surg Res. 2009;153:143-7 pubmed publisher
    ..Findings suggest that vitamin E supplements may interfere with the therapeutic effects of tamoxifen. ..
  24. Trumble T, Scarbrough A, Brown M. Osteochondral injury increases type II collagen degradation products (C2C) in synovial fluid of Thoroughbred racehorses. Osteoarthritis Cartilage. 2009;17:371-4 pubmed publisher
  25. Moreb J. Aldehyde dehydrogenase as a marker for stem cells. Curr Stem Cell Res Ther. 2008;3:237-46 pubmed
    ..We raise questions that need to be investigated before a reasonable therapeutic strategy can be devised that will effectively inhibit ALDH activity. ..
  26. Wenzlau J, Moua O, Sarkar S, Yu L, Rewers M, Eisenbarth G, et al. SlC30A8 is a major target of humoral autoimmunity in type 1 diabetes and a predictive marker in prediabetes. Ann N Y Acad Sci. 2008;1150:256-9 pubmed publisher
    ..We conclude that SLC30A8 provides an important additional and independent predictive marker for T1D. ..
  27. Leidy H, Apolzan J, Mattes R, Campbell W. Food form and portion size affect postprandial appetite sensations and hormonal responses in healthy, nonobese, older adults. Obesity (Silver Spring). 2010;18:293-9 pubmed publisher
    ..larger portions suggest that appetite control is influenced by food form and portion size in older adults. These findings may enhance the development of appropriate dietary strategies that help to regulate energy balance. ..
  28. Aytekin M, Caylak E. [Hyaluronan and the importance of hyaluronan in diagnosis and treatment]. Tuberk Toraks. 2009;57:356-64 pubmed
    ..In this review, we discussed the structure of hyaluronan and its role in diseases. ..
  29. Wang S. Epidemiology of vitamin D in health and disease. Nutr Res Rev. 2009;22:188-203 pubmed publisher
    ..The majority of the literature included in the present review is selected from that searchable in PubMed up to the end of September 2008. ..
  30. Lee H, Arnouk H, Sripathi S, Chen P, Zhang R, Bartoli M, et al. Prohibitin as an oxidative stress biomarker in the eye. Int J Biol Macromol. 2010;47:685-90 pubmed publisher
    ..Our proteomic approach implies that prohibitin in the RPE and the retina could be a new biomarker protein of oxidative stress in aging and diabetes. ..
  31. Holbrook T, McFarlane D, Schott H. Neuroendocrine and non-neuroendocrine markers of inflammation associated with performance in endurance horses. Equine Vet J Suppl. 2010;:123-8 pubmed publisher
    ..Future studies evaluating the effect of training on these markers in endurance horses are warranted. ..
  32. Boxer R, Kenny A, Cheruvu V, Vest M, Fiutem J, Piña I. Serum 25-hydroxyvitamin D concentration is associated with functional capacity in older adults with heart failure. Am Heart J. 2010;160:893-9 pubmed publisher
    ..25-Hydroxyvitamin D may be an important marker or modulator of functional capacity in patients with heart failure. Randomized controlled trials are needed to assess the effect of vitamin D repletion on functional performance. ..
  33. Valdes P, Leblond F, Kim A, Harris B, Wilson B, Fan X, et al. Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as an intraoperative biomarker. J Neurosurg. 2011;115:11-7 pubmed publisher
    ..This study is the first to measure quantitative ALA-induced PpIX concentrations in vivo, and the results have broad implications for guidance during resection of intracranial tumors. ..
  34. Chan C, Heinbokel J, Myers J, Jacobs R. Development and evaluation of a dynamic model that projects population biomarkers of methylmercury exposure from local fish consumption. Integr Environ Assess Manag. 2011;7:624-35 pubmed publisher
    ..Projected biomarkers were not different from literature sources. The model can be used as a tool to understand the impact of local fish consumption on susceptible populations. ..
  35. Coutinho T, Turner S, Kullo I. Aortic pulse wave velocity is associated with measures of subclinical target organ damage. JACC Cardiovasc Imaging. 2011;4:754-61 pubmed publisher
  36. Walia V, Yu Y, Cao D, Sun M, McLean J, Hollier B, et al. Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis. Oncogene. 2012;31:2237-46 pubmed publisher
    ..Loss of hCLCA2 may allow escape from pHi homeostatic mechanisms, permitting the higher intracellular and lower extracellular pH that are characteristic of aggressive tumor cells. ..
  37. Nunes S, Rekapally H, Chang C, Hoying J. Vessel arterial-venous plasticity in adult neovascularization. PLoS ONE. 2011;6:e27332 pubmed publisher
    ..In addition, we show that vessels of arterial identity also hold the potential to undergo sprouting angiogenesis. ..
  38. Krokowicz L, Klimczak A, Cwykiel J, Mielniczuk M, Grykien C, Siemionow M. Pulsed acoustic cellular expression as a protective therapy against I/R injury in a cremaster muscle flap model. Microvasc Res. 2012;83:213-22 pubmed publisher
    ..Both types of PACE conditioning ameliorated deleterious effect of ischemia-reperfusion injury on microcirculatory hemodynamics of muscle flaps. ..
  39. DiSilvestro R, Joseph E, Zhang W, Raimo A, Kim Y. A randomized trial of copper supplementation effects on blood copper enzyme activities and parameters related to cardiovascular health. Metabolism. 2012;61:1242-6 pubmed publisher
    ..In this test population, increased copper intake raised copper enzyme activities, but did not consistently improve the cardiovascular health measures studied. ..
  40. Satoh M, Chan J, Ross S, Li Y, Yamasaki Y, Yamada H, et al. Autoantibodies to transcription intermediary factor TIF1? associated with dermatomyositis. Arthritis Res Ther. 2012;14:R79 pubmed publisher
    ..Anti-TIF1? is a new DM autoantibody associated with a mild form of myopathy. Whether it has an association with malignancy, as in the case of anti-TIF1?, or other unique features will need to be evaluated in future studies. ..
  41. Omata J, Pierre J, Heneghan A, Tsao F, Sano Y, Jonker M, et al. Parenteral nutrition suppresses the bactericidal response of the small intestine. Surgery. 2013;153:17-24 pubmed publisher
    ..PN feeding resulted in suppressed secretion of the sPLA2 and resulted in increased bacterial survival. This demonstrates that PN significantly impairs the innate immune response by suppressing Paneth cell function. ..
  42. Furuta G, Kagalwalla A, Lee J, Alumkal P, Maybruck B, Fillon S, et al. The oesophageal string test: a novel, minimally invasive method measures mucosal inflammation in eosinophilic oesophagitis. Gut. 2013;62:1395-405 pubmed publisher
    ..The EST is a novel, minimally invasive device for measuring oesophageal eosinophilic inflammation in children with EoE. ..
  43. Bain J, Lester S, Henry W, Pongetti J, Blackman M, Johnson R. Association between maternal periapical lesions and brain inflammation in rat pups. Arch Oral Biol. 2013;58:266-71 pubmed publisher
    ..The data suggest that brain inflammation may be associated with maternal periapical inflammation. This association identifies a modifiable risk factor for adverse pregnancy outcomes. ..
  44. Meehan T, Vasilevsky N, Mungall C, Dougall D, Haendel M, Blake J, et al. Ontology based molecular signatures for immune cell types via gene expression analysis. BMC Bioinformatics. 2013;14:263 pubmed publisher
    ..This work demonstrates the utility of incorporating structured ontological knowledge into biological data analysis - providing a new method for defining novel biomarkers and providing an opportunity for new biological insights. ..
  45. Bamias G, Jia L, Cominelli F. The tumor necrosis factor-like cytokine 1A/death receptor 3 cytokine system in intestinal inflammation. Curr Opin Gastroenterol. 2013;29:597-602 pubmed publisher
    ..TL1A/DR3 interactions may participate in the pathogenesis of chronic intestinal inflammation and offer novel therapeutic targets for patients with ulcerative colitis and Crohn's disease. ..
  46. Bjartmar C, Battistuta J, Terada N, Dupree E, Trapp B. N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve. Ann Neurol. 2002;51:51-8 pubmed
    ..In addition, the results indicate that neuronal adaptation can increase N-acetylaspartate levels, and that 5 to 20% of the N-acetylaspartate in developing white matter is synthesized by proliferating oligodendrocyte progenitor cells. ..
  47. Marchi N, Fazio V, Cucullo L, Kight K, Masaryk T, Barnett G, et al. Serum transthyretin monomer as a possible marker of blood-to-CSF barrier disruption. J Neurosci. 2003;23:1949-55 pubmed
    ..Because TTR is localized primarily in choroid plexus and, as a soluble monomer, in CSF, we concluded that although S-100beta is a marker of BBB integrity, TTR instead may be a peripheral tracer of blood-to-cerebrospinal barrier. ..
  48. Vesosky B, Turner O, Turner J, Orme I. Activation marker expression on bovine peripheral blood gammadelta T cells during post-natal development and following vaccination with a commercial polyvalent viral vaccine. Dev Comp Immunol. 2003;27:439-47 pubmed
  49. Klein R, Hunter S, Jenkins A, Zheng D, Semler A, Clore J, et al. Fibrinogen is a marker for nephropathy and peripheral vascular disease in type 1 diabetes: studies of plasma fibrinogen and fibrinogen gene polymorphism in the DCCT/EDIC cohort. Diabetes Care. 2003;26:1439-48 pubmed
    ..045). Last, hyperfibrinogenemia in type 1 diabetes is associated with components of the insulin resistance syndrome trait cluster, and the association is influenced by sex. ..
  50. Pieper R, Gatlin C, McGrath A, Makusky A, Mondal M, Seonarain M, et al. Characterization of the human urinary proteome: a method for high-resolution display of urinary proteins on two-dimensional electrophoresis gels with a yield of nearly 1400 distinct protein spots. Proteomics. 2004;4:1159-74 pubmed
    ..Particularly, the decrease in abundance of the kininogen 2-DE gel spot train in urine after surgery was striking. ..
  51. Ottem E, Godwin J, Krishnan S, Petersen S. Dual-phenotype GABA/glutamate neurons in adult preoptic area: sexual dimorphism and function. J Neurosci. 2004;24:8097-105 pubmed
    ..Thus, we propose a new model for ovulation that includes dual-phenotype GABA/glutamate neurons as central transducers of hormonal and neural signals to GnRH neurons. ..
  52. Chen X, Chang L. Mycoplasma-mediated alterations of in vitro generation and functions of human dendritic cells. J Biomed Sci. 2005;12:31-46 pubmed
    ..The distinct effects of mycoplasmas on DC differentiation described in this report could potentially benefit future development of DC-based vaccination and therapeutic applications. ..
  53. Samara K, Liu C, Soldevila Pico C, Nelson D, Abdelmalek M. Betaine resolves severe alcohol-induced hepatitis and steatosis following liver transplantation. Dig Dis Sci. 2006;51:1226-9 pubmed
  54. Mrozek K, Dohner H, Bloomfield C. Influence of new molecular prognostic markers in patients with karyotypically normal acute myeloid leukemia: recent advances. Curr Opin Hematol. 2007;14:106-14 pubmed
    ..The discovery of new prognostic markers has increased our understanding of leukemogenesis and may lead to improved prognostication and generation of novel risk-adapted therapies. ..
  55. Roy S, Shah H, Rink C, Khanna S, Bagchi D, Bagchi M, et al. Transcriptome of primary adipocytes from obese women in response to a novel hydroxycitric acid-based dietary supplement. DNA Cell Biol. 2007;26:627-39 pubmed
    ..Although HCA-SX seems to be conditionally effective in weight management in experimental animals and in humans, its mechanism of action remains unclear...
  56. Mones R, Atienza K, Youssef N, Verga B, Mercer G, Rosh J. Celiac crisis in the modern era. J Pediatr Gastroenterol Nutr. 2007;45:480-3 pubmed
  57. Pittock S, Lennon V, De Seze J, Vermersch P, Homburger H, Wingerchuk D, et al. Neuromyelitis optica and non organ-specific autoimmunity. Arch Neurol. 2008;65:78-83 pubmed publisher
    ..Neuromyelitis optica spectrum disorders with seropositive findings for NMO-IgG occurring with SS/SLE or non-organ-specific autoantibodies is an indication of coexisting NMO rather than a vasculopathic or other complication of SS/SLE. ..
  58. Lane M, White T, Coutts M, Jones A, Sandhu M, Bloom D, et al. Cervical prephrenic interneurons in the normal and lesioned spinal cord of the adult rat. J Comp Neurol. 2008;511:692-709 pubmed publisher
    ..Their connectivity and relative stability after cervical hemisection raise speculation for potentially diverse roles in modulating phrenic function normally and postinjury. ..
  59. Walt D. Ubiquitous sensors: when will they be here?. ACS Nano. 2009;3:2876-80 pubmed publisher
    ..The availability of inexpensive sensors for wide-scale deployment will transform society in terms of health care as well as home and workplace monitoring. ..
  60. Miller P. Fragility fractures in chronic kidney disease: an opinion-based approach. Cleve Clin J Med. 2009;76:715-23 pubmed publisher
    ..However, even if the patient has osteoporosis, we have little evidence to guide our treatment decisions in cases of advanced chronic kidney disease. ..
  61. Rudra C, Williams M, Sheppard L, Koenig J, Schiff M, Frederick I, et al. Relation of whole blood carboxyhemoglobin concentration to ambient carbon monoxide exposure estimated using regression. Am J Epidemiol. 2010;171:942-51 pubmed publisher
    ..Monthly estimated CO exposure was moderately correlated with an exposure biomarker. These results support the validity of this regression model for estimating ambient CO exposures in this population and geographic setting. ..
  62. Pendergrass S, Hayes E, Farina G, Lemaire R, Farber H, Whitfield M, et al. Limited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury. PLoS ONE. 2010;5:e12106 pubmed publisher
    ..The identification and characterization of biomarkers for lSSc-PAH should lead to less invasive screening, a better understanding of pathogenesis, and improved treatment...
  63. Boehmer J, DeGrasse J, McFarland M, Tall E, Shefcheck K, Ward J, et al. The proteomic advantage: label-free quantification of proteins expressed in bovine milk during experimentally induced coliform mastitis. Vet Immunol Immunopathol. 2010;138:252-66 pubmed publisher
  64. Hartsock L, Barfield W, Kokko K, Liles L, Wind T, Green J, et al. Randomized prospective clinical trial comparing reamer irrigator aspirator (RIA) to standard reaming (SR) in both minimally injured and multiply injured patients with closed femoral shaft fractures treated with reamed intramedullary nailing (IMN). Injury. 2010;41 Suppl 2:S94-8 pubmed publisher
    ..Reaming and intramedullary fixation may cause an increase in IL-6 levels regardless of reamer type. Further investigations with a larger cohort of patients are desirable. ..
  65. Ezashi T, Matsuyama H, Telugu B, Roberts R. Generation of colonies of induced trophoblast cells during standard reprogramming of porcine fibroblasts to induced pluripotent stem cells. Biol Reprod. 2011;85:779-87 pubmed publisher
    ..In conclusion, reprogramming of porcine fibroblasts to iPS cells generates, as a by-product, colonies composed of self-renewing populations of TR cells, possibly containing TR stem cells. ..
  66. Govindan S, McElligott A, Muthusamy S, Nair N, Barefield D, Martin J, et al. Cardiac myosin binding protein-C is a potential diagnostic biomarker for myocardial infarction. J Mol Cell Cardiol. 2012;52:154-64 pubmed publisher
    ..The presence of elevated levels of cMyBP-C in the blood provides a promising novel biomarker able to accurately rule in MI, thus aiding in the further assessment of ischemic heart disease...
  67. Roychowdhury S, Chiang D, Mandal P, McMullen M, Liu X, Cohen J, et al. Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4 -induced fibrosis but not steatosis or inflammation. Alcohol Clin Exp Res. 2012;36:1139-47 pubmed publisher
  68. Phillips M, Basa Dalay V, Blais J, Bothamley G, Chaturvedi A, Modi K, et al. Point-of-care breath test for biomarkers of active pulmonary tuberculosis. Tuberculosis (Edinb). 2012;92:314-20 pubmed publisher
    ..A six-minute point-of-care breath test for volatile biomarkers accurately identified subjects with active pulmonary TB. ..
  69. Lopes Virella M, Hunt K, Baker N, Virella G, Moritz T. The levels of MDA-LDL in circulating immune complexes predict myocardial infarction in the VADT study. Atherosclerosis. 2012;224:526-31 pubmed publisher
    ..08 and 1.31 for MI and 0.91 and 1.34 for composite endpoint. Our study indicates that high levels of MDA-LDL in isolated IC predict future MI and acute CV events in patients with type 2 diabetes. ..
  70. Delvaux E, Bentley K, Stubbs V, Sabbagh M, Coleman P. Differential processing of amyloid precursor protein in brain and in peripheral blood leukocytes. Neurobiol Aging. 2013;34:1680-6 pubmed publisher
    ..Although our data on differential processing of APP in brain and PBL point to exercising caution when generalizing between blood and brain with regard to mechanisms, they have no implications regarding utility as biomarkers. ..
  71. Hayes D, Deeny M, Shaner C, Nixon K. Determining the threshold for alcohol-induced brain damage: new evidence with gliosis markers. Alcohol Clin Exp Res. 2013;37:425-34 pubmed publisher
    ..Little is known about the threshold of the damaging effects of alcohol. Therefore, these experiments sought to determine a threshold for brain damage using various markers of neurodegeneration...
  72. Zouein F, de Castro Brás L, da Costa D, Lindsey M, Kurdi M, Booz G. Heart failure with preserved ejection fraction: emerging drug strategies. J Cardiovasc Pharmacol. 2013;62:13-21 pubmed publisher
  73. Askovich P, Sanders C, Rosenberger C, Diercks A, Dash P, Navarro G, et al. Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses. PLoS ONE. 2013;8:e74863 pubmed publisher
    ..Because influenza infection extending into the lung generally results in severe disease, early activation of these pathways may be one factor distinguishing high- and low-pathogenicity strains. ..
  74. Perez S, Rebelo S, Anderson D. Early specification of sensory neuron fate revealed by expression and function of neurogenins in the chick embryo. Development. 1999;126:1715-28 pubmed
    ..Taken together, these data suggest that a subset of neural crest cells may already be specified for a sensory neuron fate early in migration, as a consequence of NGN expression. ..
  75. Gennuso K, Gangnon R, Matthews C, Thraen Borowski K, Colbert L. Sedentary behavior, physical activity, and markers of health in older adults. Med Sci Sports Exerc. 2013;45:1493-500 pubmed publisher
    ..Thus, older adults may benefit from the joint prescription to accumulate adequate MVPA and avoid prolonged sitting. ..
  76. Christenson L, Gunewardena S, Hong X, Spitschak M, Baufeld A, Vanselow J. Research resource: preovulatory LH surge effects on follicular theca and granulosa transcriptomes. Mol Endocrinol. 2013;27:1153-71 pubmed publisher
    ..This Research Resource provides an easy-to-access global evaluation of LH regulation in TCs and GCs that implicates numerous molecular pathways heretofore unknown within the follicle. ..
  77. Kniss D, Xie Y, Li Y, Kumar S, Linton E, Cohen P, et al. ED(27) trophoblast-like cells isolated from first-trimester chorionic villi are genetically identical to HeLa cells yet exhibit a distinct phenotype. Placenta. 2002;23:32-43 pubmed
    ..These results point out the need for adherence to rigorous and consistent quality control measures to assure the authenticity of cell lines used as in vitro model systems...
  78. Allen E, Bakke A, Purtzer M, Deodhar A. Neutrophil CD64 expression: distinguishing acute inflammatory autoimmune disease from systemic infections. Ann Rheum Dis. 2002;61:522-5 pubmed
    ..These results indicate that quantitative measurement of CD64 can distinguish between systemic infection and the flare of autoimmune diseases. ..
  79. Ruiz R, Jallo N, Murphey C, Marti C, Godbold E, Pickler R. Second trimester maternal plasma levels of cytokines IL-1Ra, Il-6 and IL-10 and preterm birth. J Perinatol. 2012;32:483-90 pubmed publisher
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