Experts and Doctors on hypercholesterolemia in Austria

Summary

Locale: Austria
Topic: hypercholesterolemia

Top Publications

  1. Schlager O, Widhalm K, Hammer A, Giurgea A, Margeta C, Fritsch M, et al. Familial hypercholesterolemia affects microvascular autoregulation in children. Metabolism. 2013;62:820-7 pubmed publisher
  2. Schmaldienst S, Goldammer A, Spitzauer S, Derfler K, Horl W, Knobl P. Local anticoagulation of the extracorporeal circuit with heparin and subsequent neutralization with protamine during immunoadsorption. Am J Kidney Dis. 2000;36:490-7 pubmed
    ..88 +/- 0.21 U/mL). No side effects or clotting of the system were observed. Our data show that this regimen of local anticoagulation is a safe protocol for extracorporeal circulation without exposing the patients to anticoagulants. ..
  3. Scharnagl H, März W. New lipid-lowering agents acting on LDL receptors. Curr Top Med Chem. 2005;5:233-42 pubmed
    ..Although these actions are not primary targets of the compounds discussed here, it is interesting that drugs inducing the LDL-R usually also lower TG and, in the case of HMGRI, increase HDL-C. ..
  4. Schobersberger W, Leichtfried V, Mueck Weymann M, Humpeler E. Austrian Moderate Altitude Studies (AMAS): benefits of exposure to moderate altitudes (1,500-2,500 m). Sleep Breath. 2010;14:201-7 pubmed publisher
    ..Active vacations at moderate altitude are associated with a variety of positive health effects in persons with metabolic syndrome and in healthy subjects. ..
  5. Humpel C. Chronic mild cerebrovascular dysfunction as a cause for Alzheimer's disease?. Exp Gerontol. 2011;46:225-32 pubmed publisher
    ..The role of NGF on the cell death of cholinergic neurons is discussed. Additional risk factors (e.g. acidosis, metals) contribute to plaque development. ..
  6. Utermann G. The mysteries of lipoprotein(a). Science. 1989;246:904-10 pubmed
    ..Though of high theoretical and practical interest, many aspects of the metabolism, function, evolution, and regulation of plasma concentrations of Lp(a) are presently unknown, controversial, or mysterious. ..
  7. Dworschak M, d Uscio L, Breukelmann D, Hannon J. Increased tolerance to hypoxic metabolic inhibition and reoxygenation of cardiomyocytes from apolipoprotein E-deficient mice. Am J Physiol Heart Circ Physiol. 2005;289:H160-7 pubmed
    ..It remains to be elucidated whether NHE1 downregulation is a unique feature of these genetically altered animals. ..
  8. Finsterer J, Unterberger U, Grisold W. Asymptomatic persistence of anti-Yo antibodies for 5 years without relapse of malignancy. Neuropathology. 2007;27:300-4 pubmed
    ..Anti-Yo antibodies may occur without the typical clinical manifestations of a NPS and may persist for years without the development of a NPS or relapse of the tumor...
  9. Rosenhek R, Baumgartner H. Aortic sclerosis, aortic stenosis and lipid-lowering therapy. Expert Rev Cardiovasc Ther. 2008;6:385-90 pubmed publisher
    ..Lipid-lowering therapy with statins can, therefore, currently only be recommended in this subgroup of patients with AS. ..

More Information

Publications11

  1. Prüller F, Raggam R, Posch V, Almer G, Truschnig Wilders M, Horejsi R, et al. Trunk weighted obesity, cholesterol levels and low grade inflammation are main determinants for enhanced thrombin generation. Atherosclerosis. 2012;220:215-8 pubmed publisher
    ..Trunk weighted obesity together with low grade inflammation and hypercholesterolemia enhance thrombin generation. ..
  2. Bartuzi P, Billadeau D, Favier R, Rong S, Dekker D, Fedoseienko A, et al. CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. Nat Commun. 2016;7:10961 pubmed publisher
    ..Altogether, this study provides valuable insights into the mechanisms regulating cholesterol homeostasis and LDLR trafficking. ..