Experts and Doctors on humans in Netherlands


Locale: Netherlands
Topic: humans

Top Publications

  1. Zhao W, Kote Jarai Z, van Santen Y, Hofsteenge J, Beintema J. Ribonucleases from rat and bovine liver: purification, specificity and structural characterization. Biochim Biophys Acta. 1998;1384:55-65 pubmed
    ..Bovine, porcine and rat liver-type ribonucleases showed a strong preference for poly(U) over poly(C). This preference is a unique property of the liver-type enzymes of the ribonuclease superfamily. ..
  2. Louwman M, van Dusseldorp M, van de Vijver F, Thomas C, Schneede J, Ueland P, et al. Signs of impaired cognitive function in adolescents with marginal cobalamin status. Am J Clin Nutr. 2000;72:762-9 pubmed
    ..38; 95% CI: -0.62, - 0.14). Our data suggest that cobalamin deficiency, in the absence of hematologic signs, may lead to impaired cognitive performance in adolescents. ..
  3. van der Flier A, Kuikman I, Kramer D, Geerts D, Kreft M, Takafuta T, et al. Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits. J Cell Biol. 2002;156:361-76 pubmed
    ..These findings suggest that specific combinations of filamin mRNA splicing events modulate the organization of the actin cytoskeleton and the binding affinity for integrins. ..
  4. Jansens A, van Duijn E, Braakman I. Coordinated nonvectorial folding in a newly synthesized multidomain protein. Science. 2002;298:2401-3 pubmed
    ..Thus, productive LDL-R folding in a cell is not vectorial but is mostly posttranslational, and involves transient long-range non-native disulfide bonds that are isomerized into native short-range cysteine pairs. ..
  5. Janssen D, Alsemgeest T, Widdershoven G, Wouters E, Schols J, Spruit M. The last wish of a patient with end stage chronic obstructive pulmonary disease. BMJ. 2008;337:a2701 pubmed publisher
  6. Schulte Merker S, Sabine A, Petrova T. Lymphatic vascular morphogenesis in development, physiology, and disease. J Cell Biol. 2011;193:607-18 pubmed publisher
    ..It is now crucial to use this knowledge for the development of novel therapies for human diseases. ..
  7. Klein Klouwenberg P, Ong D, Bos L, de Beer F, van Hooijdonk R, Huson M, et al. Interobserver agreement of Centers for Disease Control and Prevention criteria for classifying infections in critically ill patients. Crit Care Med. 2013;41:2373-8 pubmed publisher
    ..However, full concordance on all aspects of the diagnosis between independent observers was rare for some types of infection, in particular for ventilator-associated pneumonia. ..
  8. Guchelaar H, Gelderblom H, van der Straaten T, Schellens J, Swen J. Pharmacogenetics in the cancer clinic: from candidate gene studies to next-generation sequencing. Clin Pharmacol Ther. 2014;95:383-5 pubmed publisher
    ..With the rapid advances in sequencing technologies, decline in costs, and swift turnaround times, large-scale genomic information will become available in the clinical setting, facilitating implementation of pharmacogenetics. ..
  9. Paugh S, Bonten E, Savic D, Ramsey L, Thierfelder W, Gurung P, et al. NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells. Nat Genet. 2015;47:607-14 pubmed publisher
    ..The broad impact on the glucocorticoid transcriptional response suggests that this mechanism could also modify glucocorticoid effects in other diseases. ..

More Information

Publications641 found, 100 shown here

  1. Verweij S, Karimi O, Pleijster J, Lyons J, de Vries H, Land J, et al. TLR2, TLR4 and TLR9 genotypes and haplotypes in the susceptibility to and clinical course of Chlamydia trachomatis infections in Dutch women. Pathog Dis. 2016;74:ftv107 pubmed publisher
    ..trachomatis infections (OR: 0.4, P = 0.004). Our study shows that both TLR2 and TLR9 genes and SNP combinations do influence the clinical course of Chlamydia infections. ..
  2. Bron T, Bijlenga D, Verduijn J, Penninx B, Beekman A, Kooij J. Prevalence of ADHD symptoms across clinical stages of major depressive disorder. J Affect Disord. 2016;197:29-35 pubmed publisher
    ..ADHD symptoms are very common among MDD patients, especially among those in recurrent and chronic stages of MDD. Considering ADHD may be an important step forward in improving the treatment of depression. ..
  3. Sittig S, Bakdash G, Weiden J, Sköld A, Tel J, Figdor C, et al. A Comparative Study of the T Cell Stimulatory and Polarizing Capacity of Human Primary Blood Dendritic Cell Subsets. Mediators Inflamm. 2016;2016:3605643 pubmed publisher
    ..These findings further establish all three human blood DCs-despite their differences-as promising candidates for immunostimulatory effectors in cancer immunotherapy. ..
  4. Welters M, van der Sluis T, van Meir H, Loof N, van Ham V, van Duikeren S, et al. Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses. Sci Transl Med. 2016;8:334ra52 pubmed publisher
    ..In conclusion, carboplatin-paclitaxel therapy fosters vigorous vaccine-induced T cell responses when vaccination is given after chemotherapy and has reset the tumor-induced abnormal myeloid cell composition to normal values. ..
  5. van Giessen A, Peters J, Wilcher B, Hyde C, Moons C, de Wit A, et al. Systematic Review of Health Economic Impact Evaluations of Risk Prediction Models: Stop Developing, Start Evaluating. Value Health. 2017;20:718-726 pubmed publisher
    ..Guidance on HEE of PMs could encourage and standardize their application and enhance methodological quality, thereby improving adequate use of PM strategies. ..
  6. Bunge E, Essink Bot M, Kobussen M, van Suijlekom Smit L, Moll H, Raat H. Reliability and validity of health status measurement by the TAPQOL. Arch Dis Child. 2005;90:351-8 pubmed
    ..Results showed that the TAPQOL is a feasible instrument to measure HRQoL and support the reliability and discriminative validity of the majority of its scales for infants as well as toddlers. ..
  7. Peul W, Van Den Hout W, Brand R, Thomeer R, Koes B. Prolonged conservative care versus early surgery in patients with sciatica caused by lumbar disc herniation: two year results of a randomised controlled trial. BMJ. 2008;336:1355-8 pubmed publisher
    ..Early surgery achieved more rapid relief of sciatica than conservative care, but outcomes were similar by one year and these did not change during the second year. ISRCT No 26872154. ..
  8. de Ruyter J, Olthof M, Kuijper L, Katan M. Effect of sugar-sweetened beverages on body weight in children: design and baseline characteristics of the Double-blind, Randomized INtervention study in Kids. Contemp Clin Trials. 2012;33:247-57 pubmed publisher
    ..It would also suggest that a reduction in liquid sugars could decrease body fat more effectively than reduction of other calorie sources. ..
  9. Rosenkötter N, Achterberg P, van Bon Martens M, Michelsen K, van Oers H, Brand H. Key features of an EU health information system: a concept mapping study. Eur J Public Health. 2016;26:65-70 pubmed publisher
    ..This study provides insights into key features of an EU-HISys. The results can be used to guide future planning and to support the development of a health information system for Europe. ..
  10. Omidvari A, Meester R, Lansdorp Vogelaar I. Cost effectiveness of surveillance for GI cancers. Best Pract Res Clin Gastroenterol. 2016;30:879-891 pubmed publisher
    ..Further studies based on more robust effectiveness evidence are needed to inform and optimise surveillance programmes for GI cancers. ..
  11. Bom M, van der Heijden D, Kedhi E, Van der Heyden J, Meuwissen M, Knaapen P, et al. Early Detection and Treatment of the Vulnerable Coronary Plaque: Can We Prevent Acute Coronary Syndromes?. Circ Cardiovasc Imaging. 2017;10: pubmed publisher
    ..Results from these studies may enable a more patient-tailored strategy for the treatment of coronary artery disease. ..
  12. Heesen M, Bloemeke B, Kunz D. The cytokine synthesis by heterozygous carriers of the Toll-like receptor 4 Asp299Gly polymorphism does not differ from that of wild type homozygotes. Eur Cytokine Netw. 2003;14:234-7 pubmed
    ..Our study suggests that heterozygosity for this TLR4 mutation is not a major factor determining the cytokine response to endotoxin. ..
  13. Heemskerk M, Hoogeboom M, Hagedoorn R, Kester M, Willemze R, Falkenburg J. Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer. J Exp Med. 2004;199:885-94 pubmed
  14. De Winter F, Vo T, Stam F, Wisman L, Bär P, Niclou S, et al. The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease. Mol Cell Neurosci. 2006;32:102-17 pubmed
    ..We propose that expression of Sema3A by TSCs not only suppresses nerve terminal plasticity at specific neuromuscular synapses, but may also contribute to their early and selective loss in the motor neuron disease ALS. ..
  15. Bouwens M, van de Rest O, Dellschaft N, Bromhaar M, de Groot L, Geleijnse J, et al. Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells. Am J Clin Nutr. 2009;90:415-24 pubmed publisher
    ..These results are the first to show that intake of EPA+DHA for 26 wk can alter the gene expression profiles of PBMCs to a more antiinflammatory and antiatherogenic status. This trial was registered at as NCT00124852. ..
  16. Tucha L, Tucha O, Sontag T, Stasik D, Laufkötter R, Lange K. Differential effects of methylphenidate on problem solving in adults with ADHD. J Atten Disord. 2011;15:161-73 pubmed publisher
    ..Pharmacological treatment of adults with ADHD revealed a differential effect of MPH on problem solving abilities. ..
  17. Stigt J, tHart N, Knol A, Uil S, Groen H. Pyrosequencing analysis of EGFR and KRAS mutations in EUS and EBUS-derived cytologic samples of adenocarcinomas of the lung. J Thorac Oncol. 2013;8:1012-8 pubmed publisher
    ..Pyrosequencing on cytological blocks, especially older tumor blocks, is feasible with a high diagnostic success rate. Failures in HRM were observed in DNA samples with short fragments related to longer storage times. ..
  18. Mayboroda O, van Hooij A, Derks R, van den Eeden S, Dijkman K, Khadge S, et al. Exploratory urinary metabolomics of type 1 leprosy reactions. Int J Infect Dis. 2016;45:46-52 pubmed publisher
  19. van der Vleuten C. Validity of final examinations in undergraduate medical training. BMJ. 2000;321:1217-9 pubmed
  20. Hanse M, Vincent A, van den Bent M. Hemangioblastomatosis in a patient with von Hippel-Lindau disease. J Neurooncol. 2007;82:163-4 pubmed
  21. Bende R, Van Maldegem F, Triesscheijn M, Wormhoudt T, Guijt R, van Noesel C. Germinal centers in human lymph nodes contain reactivated memory B cells. J Exp Med. 2007;204:2655-65 pubmed
  22. Wallinga J, van Boven M, Lipsitch M. Optimizing infectious disease interventions during an emerging epidemic. Proc Natl Acad Sci U S A. 2010;107:923-8 pubmed publisher
  23. Webbink D, Martin N, Visscher P. Does education reduce the probability of being overweight?. J Health Econ. 2010;29:29-38 pubmed publisher
    ..Identical twin sisters who differ in educational attainment do not systematically differ in body size. Peer effects within pairs of identical twin sisters might play a role. ..
  24. Koek M, Sigurdsson V, van Weelden H, Steegmans P, Bruijnzeel Koomen C, Buskens E. Cost effectiveness of home ultraviolet B phototherapy for psoriasis: economic evaluation of a randomised controlled trial (PLUTO study). BMJ. 2010;340:c1490 pubmed publisher
    ..Current Controlled Trials ISRCTN83025173 and NCT00150930. ..
  25. van der Marel S, Comijn E, Verspaget H, van Deventer S, van den Brink G, Petry H, et al. Neutralizing antibodies against adeno-associated viruses in inflammatory bowel disease patients: implications for gene therapy. Inflamm Bowel Dis. 2011;17:2436-42 pubmed publisher
    ..Furthermore, we show a relationship between disease phenotype in IBD patients and the humoral immune response to AAV. ..
  26. van de Port I, Wevers L, Lindeman E, Kwakkel G. Effects of circuit training as alternative to usual physiotherapy after stroke: randomised controlled trial. BMJ. 2012;344:e2672 pubmed publisher
    ..Dutch Trial Register (NTR1534). ..
  27. Zandbelt B, Bloemendaal M, Hoogendam J, Kahn R, Vink M. Transcranial magnetic stimulation and functional MRI reveal cortical and subcortical interactions during stop-signal response inhibition. J Cogn Neurosci. 2013;25:157-74 pubmed publisher
    ..These findings extend our knowledge about the functional organization of inhibitory control, an important component of executive functioning, showing that rIFC exerts reactive control over M1 via SMC and right striatum. ..
  28. Mooij S, van der Klis F, van der Sande M, Schepp R, Speksnijder A, Bogaards J, et al. Seroepidemiology of high-risk HPV in HIV-negative and HIV-infected MSM: the H2M study. Cancer Epidemiol Biomarkers Prev. 2013;22:1698-708 pubmed publisher
    ..HIV infection is a strong and independent determinant for HPV seropositivity, which we hypothesize is because of increased persistence of HPV infection in HIV-infected MSM. ..
  29. De Roo M, Albers G, Deliens L, de Vet H, Francke A, Van den Noortgate N, et al. Physical and Psychological Distress Are Related to Dying Peacefully in Residents With Dementia in Long-Term Care Facilities. J Pain Symptom Manage. 2015;50:1-8 pubmed publisher
    ..Further qualitative research is recommended to gain more in-depth insights into the aspects on which relatives base their judgment of dying peacefully. ..
  30. Möller C, Hafkemeijer A, Pijnenburg Y, Rombouts S, van der Grond J, Dopper E, et al. Different patterns of cortical gray matter loss over time in behavioral variant frontotemporal dementia and Alzheimer's disease. Neurobiol Aging. 2016;38:21-31 pubmed publisher
    ..Decline of cognitive performances was in line with cortical thinning and deteriorated the most in AD patients. ..
  31. Benders A, van Kuppevelt T, Oosterhof A, Wevers R, Veerkamp J. Adenosine triphosphatases during maturation of cultured human skeletal muscle cells and in adult human muscle. Biochim Biophys Acta. 1992;1112:89-98 pubmed
  32. Stolk W, de Vlas S, Habbema J. Anti-Wolbachia treatment for lymphatic filariasis. Lancet. 2005;365:2067-8 pubmed
  33. Franssen M, Korevaar J, van der Veen F, Leschot N, Bossuyt P, Goddijn M. Reproductive outcome after chromosome analysis in couples with two or more miscarriages: index [corrected]-control study. BMJ. 2006;332:759-63 pubmed
    ..Their chances of having a healthy child are as high as non-carrier couples, despite a higher risk of miscarriage. ..
  34. Huurman V, Kalpoe J, van de Linde P, Vaessen N, Ringers J, Kroes A, et al. Choice of antibody immunotherapy influences cytomegalovirus viremia in simultaneous pancreas-kidney transplant recipients. Diabetes Care. 2006;29:842-7 pubmed
    ..These findings may prove valuable in the discussion on both safety of induction therapy and recurrent autoimmunity in SPK and islet transplantation. ..
  35. Benitez Ribas D, Adema G, Winkels G, Klasen I, Punt C, Figdor C, et al. Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after Fc gamma RII-mediated uptake. J Exp Med. 2006;203:1629-35 pubmed
    ..Antigen presentation by pDCs may thus modulate the strength and quality of the secondary phase of an immune response. ..
  36. Jongerius I, K hl J, Pandey M, Ruyken M, Van Kessel K, Van Strijp J, et al. Staphylococcal complement evasion by various convertase-blocking molecules. J Exp Med. 2007;204:2461-71 pubmed publisher
    ..The strong antiinflammatory properties of these novel S. aureus-derived convertase inhibitors make these compounds interesting drug candidates for complement-mediated diseases...
  37. Heymans R, Schouls L, van der Heide H, van der Loeff M, Bruisten S. Multiple-locus variable-number tandem repeat analysis of Neisseria gonorrhoeae. J Clin Microbiol. 2011;49:354-63 pubmed publisher
    ..MLVA provided accurate identification of genetically related N. gonorrhoeae strains and revealed clusters of MSM and heterosexuals reflecting distinct transmission networks. ..
  38. Simons R, Wilschut E, Valk P. Sleep and alertness in North Sea helicopter operations. Aviat Space Environ Med. 2011;82:704-10 pubmed
    ..Appropriate FDP scheduling is an important measure to optimize alertness of helicopter pilots who have to cope with adverse environmental conditions and limited landing and air traffic control facilities. ..
  39. Lugnér A, van Boven M, de Vries R, Postma M, Wallinga J. Cost effectiveness of vaccination against pandemic influenza in European countries: mathematical modelling analysis. BMJ. 2012;345:e4445 pubmed publisher
    ..With aging populations, pre-existing immunity in particular could be of crucial importance for the cost effectiveness of options to mitigate a future influenza pandemic. ..
  40. Utens C, Goossens L, van Schayck O, Rutten van Mölken M, van Litsenburg W, Janssen A, et al. Patient preference and satisfaction in hospital-at-home and usual hospital care for COPD exacerbations: results of a randomised controlled trial. Int J Nurs Stud. 2013;50:1537-49 pubmed publisher
    ..Results support the wider implementation of early assisted discharge for COPD exacerbations and this treatment option should be offered to selected patients that prefer home treatment. ..
  41. Raaijmakers J, Tanenbaum M, Medema R. Systematic dissection of dynein regulators in mitosis. J Cell Biol. 2013;201:201-15 pubmed publisher
  42. van den Dries K, Schwartz S, Byars J, Meddens M, Bolomini Vittori M, Lidke D, et al. Dual-color superresolution microscopy reveals nanoscale organization of mechanosensory podosomes. Mol Biol Cell. 2013;24:2112-23 pubmed publisher
    ..Our findings call for a reevaluation of the current "core-ring" model and provide a novel structural framework for further understanding the collective behavior of podosome clusters. ..
  43. Veltman C, Beeres S, Kalkman D, Kelder T, Kies P, Vliegen H, et al. Variation in coronary anatomy in adult patients late after arterial switch operation: a computed tomography coronary angiography study. Ann Thorac Surg. 2013;96:1390-1397 pubmed publisher
    ..Neoaortic root dilation and a higher coronary takeoff may explain part of the pathophysiology. Long-term follow-up is needed to determine the clinical significance of these findings. ..
  44. Reusken C, Haagmans B, Muller M, Gutierrez C, Godeke G, Meyer B, et al. Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study. Lancet Infect Dis. 2013;13:859-66 pubmed publisher
    ..Both titres and seroprevalences in sera from different locations in Oman suggest widespread infection. European Union, European Centre For Disease Prevention and Control, Deutsche Forschungsgemeinschaft. ..
  45. Pieper P, Balci A, Aarnoudse J, Kampman M, Sollie K, Groen H, et al. Uteroplacental blood flow, cardiac function, and pregnancy outcome in women with congenital heart disease. Circulation. 2013;128:2478-87 pubmed publisher
    ..Cardiovascular function is associated with an abnormal pattern of UDF. Compromised UDF may be a key factor in the high incidence of offspring and obstetric complications in this population. ..
  46. Hatano K, Sugimura K, Crocetti E. Looking at the dark and bright sides of identity formation: New insights from adolescents and emerging adults in Japan. J Adolesc. 2016;47:156-68 pubmed publisher
    ..Clinical implications for identity research and intervention programs are discussed. ..
  47. Onrust S, Otten R, Lammers J, Smit F. School-based programmes to reduce and prevent substance use in different age groups: What works for whom? Systematic review and meta-regression analysis. Clin Psychol Rev. 2016;44:45-59 pubmed publisher
    ..The various developmental stages offer different possibilities and opportunities for the reduction and prevention of substance use. ..
  48. Al Hatmi A, Mirabolfathy M, Hagen F, Normand A, Stielow J, Karami Osbo R, et al. DNA barcoding, MALDI-TOF, and AFLP data support Fusarium ficicrescens as a distinct species within the Fusarium fujikuroi species complex. Fungal Biol. 2016;120:265-78 pubmed publisher
    ..TEF1 was confirmed as an essential barcode for identifying Fusarium species. In addition to TEF1, we evaluated BT2 and RPB2 in order to provide sufficient genetic and species boundaries information for recognition of the novel species. ..
  49. Walraven I, van den Heuvel M, van Diessen J, Schaake E, Uyterlinde W, Aerts J, et al. Long-term follow-up of patients with locally advanced non-small cell lung cancer receiving concurrent hypofractionated chemoradiotherapy with or without cetuximab. Radiother Oncol. 2016;118:442-6 pubmed publisher
    ..In this phase II trial, the median OS for the entire group was remarkably high; 31.5 months. Furthermore, 5-year OS was still 37.3%. Hypofractionation might contribute to improved OS in LA-NSCLC patients. ..
  50. Keppel Hesselink J. The terms 'autacoid', 'hormone' and 'chalone' and how they have shifted with time. Auton Autacoid Pharmacol. 2015;35:51-8 pubmed publisher
    ..Our exploration demonstrates that biomedical concepts can be constructed and defined differently as time goes by, while concept transformations seem to emerge without arguments. ..
  51. Ochodnicky P, Lattenist L, Ahdi M, Kers J, Uil M, Claessen N, et al. Increased Circulating and Urinary Levels of Soluble TAM Receptors in Diabetic Nephropathy. Am J Pathol. 2017;187:1971-1983 pubmed publisher
    ..Renal injury in diabetes is associated with elevated systemic and urine levels of sMer and sTyro3. This is the first study reporting excretion of sTAM receptors in urine, identifying the kidney as a source of sTAM. ..
  52. Drost J, van Boxtel R, Blokzijl F, Mizutani T, Sasaki N, Sasselli V, et al. Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer. Science. 2017;358:234-238 pubmed publisher
    ..We show that signature 30 can arise from germline NTHL1 mutations. ..
  53. van Iersel J, Formijne Jonkers H, Paulides T, Verheijen P, Draaisma W, Consten E, et al. Robot-Assisted Ventral Mesh Rectopexy for Rectal Prolapse: A 5-Year Experience at a Tertiary Referral Center. Dis Colon Rectum. 2017;60:1215-1223 pubmed publisher
    ..Robotic assistance appears advantageous for this procedure, but literature regarding robot-assisted ventral mesh rectopexy is limited...
  54. Dallinga Thie G, Van Tol A, Hattori H, Rensen P, Sijbrands E. Plasma phospholipid transfer protein activity is decreased in type 2 diabetes during treatment with atorvastatin: a role for apolipoprotein E?. Diabetes. 2006;55:1491-6 pubmed
    ..The activity of PLTP in type 2 diabetes is decreased by atorvastatin. The association between the decrease in PLTP activity and apoE during statin treatment supports the hypothesis that apoE may prevent PLTP inactivation. ..
  55. Hermans M, Henry R, Dekker J, Kooman J, Kostense P, Nijpels G, et al. Estimated glomerular filtration rate and urinary albumin excretion are independently associated with greater arterial stiffness: the Hoorn Study. J Am Soc Nephrol. 2007;18:1942-52 pubmed
    ..These findings may explain, in part, why eGFR and microalbuminuria are associated with greater risk for CVD and suggest that amelioration of arterial stiffness could be a target of intervention. ..
  56. Marteijn J, Bekker Jensen S, Mailand N, Lans H, Schwertman P, Gourdin A, et al. Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response. J Cell Biol. 2009;186:835-47 pubmed publisher
    ..Although both lesions are processed by independent repair pathways and trigger signaling responses by distinct kinases, they eventually generate the same epigenetic mark, possibly functioning in DNA damage signal amplification. ..
  57. van Duijkeren E, Kamphuis M, van der Mije I, Laarhoven L, Duim B, Wagenaar J, et al. Transmission of methicillin-resistant Staphylococcus pseudintermedius between infected dogs and cats and contact pets, humans and the environment in households and veterinary clinics. Vet Microbiol. 2011;150:338-43 pubmed publisher
  58. Stiggelbout A, van der Weijden T, de Wit M, Frosch D, Legare F, Montori V, et al. Shared decision making: really putting patients at the centre of healthcare. BMJ. 2012;344:e256 pubmed publisher
    ..Although many clinicians feel they already use shared decision making, research shows a perception-reality gap. A M Stiggelbout and colleagues discuss why it is important and highlight some best practices. ..
  59. van Ee E, Kleber R. Child in the shadowlands. Lancet. 2012;380:642-3 pubmed
  60. Reis Miranda D, Jegers M. Monitoring costs in the ICU: a search for a pertinent methodology. Acta Anaesthesiol Scand. 2012;56:1104-13 pubmed publisher
  61. Teunissen C, Menge T, Altintas A, Alvarez Cermeño J, Bertolotto A, Berven F, et al. Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis. Mult Scler. 2013;19:1802-9 pubmed publisher
    ..Application of these uniform definitions will lead to better comparability of biomarker studies and optimal use of available resources. This will lead to improved quality of CSF biomarker research in MS and related disorders. ..
  62. Wiegant K, van Roermund P, Intema F, Cotofana S, Eckstein F, Mastbergen S, et al. Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis. Osteoarthritis Cartilage. 2013;21:1660-7 pubmed publisher
    ..Cartilage repair is still present after 2 years (MRI) and the newly formed tissue continues to be mechanically resilient as shown by an increased JSW under weight-bearing conditions. ..
  63. Bohlmeijer E, Lamers S, Fledderus M. Flourishing in people with depressive symptomatology increases with Acceptance and Commitment Therapy. Post-hoc analyses of a randomized controlled trial. Behav Res Ther. 2015;65:101-6 pubmed publisher
    ..In addition to levels of positive mental health at baseline, an increase of psychological flexibility during the intervention was a significant predictor of flourishing at the three-month follow-up. ..
  64. Mangen M, Rozenbaum M, Huijts S, van Werkhoven C, Postma D, Atwood M, et al. Cost-effectiveness of adult pneumococcal conjugate vaccination in the Netherlands. Eur Respir J. 2015;46:1407-16 pubmed publisher
    ..PCV13 vaccination is highly cost-effective in the Netherlands. The transferability of our results to other countries depends upon vaccination strategies already implemented in those countries. ..
  65. Te Riele A, James C, Groeneweg J, Sawant A, Kammers K, Murray B, et al. Approach to family screening in arrhythmogenic right ventricular dysplasia/cardiomyopathy. Eur Heart J. 2016;37:755-63 pubmed publisher
    ..Siblings have highest risk of disease, even after correcting for age and sex. Fulfilment of TFC independent of family history is superior to conventional TFC for arrhythmic risk stratification of relatives. ..
  66. Reuland E, al Naiemi N, Kaiser A, Heck M, Kluytmans J, Savelkoul P, et al. Prevalence and risk factors for carriage of ESBL-producing Enterobacteriaceae in Amsterdam. J Antimicrob Chemother. 2016;71:1076-82 pubmed publisher
    ..A major risk factor in the general population was travel to countries outside Europe, in particular to Asia, Africa and Northern America. ..
  67. Steenhuis L, Bartels Velthuis A, Jenner J, Aleman A, Bruggeman R, Nauta M, et al. Religiosity in young adolescents with auditory vocal hallucinations. Psychiatry Res. 2016;236:158-164 pubmed publisher
    ..A speculative explanation may be that religious practices were adopted in response to AVH as a method of coping. ..
  68. Boekhout M, Yuan R, Wondergem A, Segeren H, van Liere E, Awol N, et al. Feedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progression. EMBO Rep. 2016;17:414-27 pubmed publisher
    ..In conclusion, we discovered a feedback loop between atypical E2Fs and APC/C(C) (dh1), which ensures balanced expression of cell cycle genes and normal cell cycle progression. ..
  69. Bours M, van der Linden B, Winkels R, van Duijnhoven F, Mols F, van Roekel E, et al. Candidate Predictors of Health-Related Quality of Life of Colorectal Cancer Survivors: A Systematic Review. Oncologist. 2016;21:433-52 pubmed publisher
    ..This systematic review outlines candidate predictors of low quality of life of colorectal cancer survivors, providing a firm conceptual basis for developing prediction models. ..
  70. van den Houten M, Van Grinsven R, Pouwels S, Yo L, Van Sambeek M, Teijink J. Treatment of upper-extremity outflow thrombosis. Phlebology. 2016;31:28-33 pubmed publisher
    ..However, several controversies exist regarding their indication and timing. ..
  71. Klijn S, Sicam V, Reus N. Long-term changes in intraocular lens position and corneal curvature after cataract surgery and their effect on refraction. J Cataract Refract Surg. 2016;42:35-43 pubmed publisher
    ..These fluctuations limit the accuracy with which the refractive outcome can be planned. No author has a financial or proprietary interest in any material or method mentioned. ..
  72. van Schagen I, Commandeur J, Goldenbeld C, Stipdonk H. Monitoring speed before and during a speed publicity campaign. Accid Anal Prev. 2016;97:326-334 pubmed publisher
    ..The only exception was an effect of local speed limit reminders on the 30km/h roads. This effect, however, was temporary and had disappeared within a week. ..
  73. Leurs R, Hoffmann M, Wieland K, Timmerman H. H3 receptor gene is cloned at last. Trends Pharmacol Sci. 2000;21:11-2 pubmed
  74. Elferink R, Groen A. Genetic defects in hepatobiliary transport. Biochim Biophys Acta. 2002;1586:129-45 pubmed
    ..Four of these transporter genes are associated with inherited diseases. In this minireview we will shortly describe our present understanding of bile formation and the associated inherited defects...
  75. Rangarajan S, Enserink J, Kuiperij H, de Rooij J, Price L, Schwede F, et al. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor. J Cell Biol. 2003;160:487-93 pubmed
    ..From these results we conclude that cAMP mediates receptor-induced integrin-mediated cell adhesion to fibronectin through the Epac-Rap1 signaling pathway. ..
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    ..Other potential sources of heterogeneity should be investigated to ensure implementation of evidence-based improvements in diabetes care. ..
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    ..Furthermore, the elderly adapted their reflexive stiffness around the ankle joint less compared with young participants. These results imply that elderly were stiffer and were less able to adapt to external force fields. ..
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    ..Though electronic data collection has enormous potential, this study shows that e-mail yields unacceptable low response rates. It is too early to replace traditional pen-and-paper PROM's by electronic questionnaires. ..
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    ..These data provide insights into potential adverse effects of LDL-C-lowering therapy. ..
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    ..Normal sCD27 concentrations in CSF samples of patients with chronic lymphoproliferation makes LI unlikely, but the determination of CSF sCD27 is not sufficiently specific to serve as a reliable tumor marker. ..