Experts and Doctors on halobacterium in Germany


Locale: Germany
Topic: halobacterium

Top Publications

  1. Geibel S, Friedrich T, Ormos P, Wood P, Nagel G, Bamberg E. The voltage-dependent proton pumping in bacteriorhodopsin is characterized by optoelectric behavior. Biophys J. 2001;81:2059-68 pubmed
    ..From the results we conclude that the transport cycle of bR branches via a long-lived M(1)* in a voltage-dependent manner into a nontransporting cycle, where the proton release and uptake occur on the extracellular side. ..
  2. Pfeifer F, Gregor D, Hofacker A, Plösser P, Zimmermann P. Regulation of gas vesicle formation in halophilic archaea. J Mol Microbiol Biotechnol. 2002;4:175-81 pubmed
    ..Eight of the fourteen p-gvp genes (p-gvpAO and p-gvpFGJKLM) enable gas vesicle formation in Hf. volcanii transformants and thus constitute the minimal p-vac region. ..
  3. Gropp F, Grampp B, Stolt P, Palm P, Zillig W. The immunity-conferring plasmid p phi HL from the Halobacterium salinarium phage phi H: nucleotide sequence and transcription. Virology. 1992;190:45-54 pubmed
    ..Lytic transcription is shown to be strictly time-dependent, with an early gene product required for the expression of late genes. ..
  4. Stolt P, Zillig W. Antisense RNA mediates transcriptional processing in an archaebacterium, indicating a novel kind of RNase activity. Mol Microbiol. 1993;7:875-82 pubmed
    ..The single-stranded ends of RNA are cut off at the ends of the 151 nt RNA duplex, removing the ribosomal binding sites from the first open reading frame of transcript T1 but without concomitant digestion of the products. ..
  5. Pfeifer F, Kruger K, Roder R, Mayr A, Ziesche S, Offner S. Gas vesicle formation in halophilic Archaea. Arch Microbiol. 1997;167:259-68 pubmed
    ..Each vac region exhibits a characteristic transcription pattern, and regulatory steps have been observed at the DNA, RNA, and protein level, indicating a complex regulatory network acting during gas vesicle gene expression. ..
  6. Bondar A, Elstner M, Suhai S, Smith J, Fischer S. Mechanism of primary proton transfer in bacteriorhodopsin. Structure. 2004;12:1281-8 pubmed
    ..This result reconciles the conflicting views held on the mechanism and suggests a strategy by which the protein renders this essential step resilient. ..
  7. Kessler M, Gottschalk K, Janovjak H, Muller D, Gaub H. Bacteriorhodopsin folds into the membrane against an external force. J Mol Biol. 2006;357:644-54 pubmed
    ..Subsequent unfolding allowed us to analyze the pattern of unfolding barriers and corroborate that the protein had refolded into the native state. ..
  8. Patenge N, Haase A, Bolhuis H, Oesterhelt D. The gene for a halophilic beta-galactosidase (bgaH) of Haloferax alicantei as a reporter gene for promoter analyses in Halobacterium salinarum. Mol Microbiol. 2000;36:105-13 pubmed
    ..Therefore, the bgaH gene of Haloferax alicantei appears to be a useful tool for in vivo studies of gene expression in Halobacterium salinarum and possibly other halophilic Archaea...
  9. Pamnani V, Tamura T, Lupas A, Peters J, Cejka Z, Ashraf W, et al. Cloning, sequencing and expression of VAT, a CDC48/p97 ATPase homologue from the archaeon Thermoplasma acidophilum. FEBS Lett. 1997;404:263-8 pubmed
    ..Electron microscopy shows the purified protein to form single and double homo-hexameric rings. Although the symmetry is different, the appearance of the complexes formed of two rings resembles the 20S proteasome and Hsp60/GroEL...

More Information


  1. Soppa J, Duschl J, Oesterhelt D. Bacterioopsin, haloopsin, and sensory opsin I of the halobacterial isolate Halobacterium sp. strain SG1: three new members of a growing family. J Bacteriol. 1993;175:2720-6 pubmed
  2. Kimura M, Arndt E, Hatakeyama T, Kimura J. Ribosomal proteins in halobacteria. Can J Microbiol. 1989;35:195-9 pubmed
    ..In addition, halophilic proteins seem to lose isoleucine as compared with Escherichia coli ribosomal proteins...
  3. Horne M, Englert C, Wimmer C, Pfeifer F. A DNA region of 9 kbp contains all genes necessary for gas vesicle synthesis in halophilic archaebacteria. Mol Microbiol. 1991;5:1159-74 pubmed
    ..However, gas vesicle synthesis could be restored in each Vac mutant containing an ISH element when the entire transcription unit encompassing the mutated gene on pHH1 was present in the wild-type form on the vector construct. ..
  4. Seitz A, Schneider F, Pasternack R, Fuchsbauer H, Hampp N. Enzymatic cross-linking of purple membranes catalyzed by bacterial transglutaminase. Biomacromolecules. 2001;2:233-8 pubmed
    ..Furthermore, this finding may provide the ability to achieve covalent linkage of complete purple membrane patches to synthetic polymers...
  5. Patenge N, Berendes A, Engelhardt H, Schuster S, Oesterhelt D. The fla gene cluster is involved in the biogenesis of flagella in Halobacterium salinarum. Mol Microbiol. 2001;41:653-63 pubmed
    ..Therefore, the flaI gene product is involved in the biosynthesis, transport or assembly of flagella in H. salinarum...
  6. Streif S, Staudinger W, Oesterhelt D, Marwan W. Quantitative analysis of signal transduction in motile and phototactic cells by computerized light stimulation and model based tracking. Rev Sci Instrum. 2009;80:023709 pubmed publisher
    ..Overall, the setup is flexible, extensible, and consists mainly of commercially available products. This facilitates modifications of the setup and algorithms for physiological studies of the motility of cells or microorganisms...
  7. Schlesner M, Miller A, Besir H, Aivaliotis M, Streif J, Scheffer B, et al. The protein interaction network of a taxis signal transduction system in a halophilic archaeon. BMC Microbiol. 2012;12:272 pubmed publisher
    ..Secondly, we propose a hypothetical feedback loop from the response regulator to Htr methylation made from the CheC proteins, CheD and CheB, which might contribute to adaptation analogous to the CheC/CheD system of B. subtilis. ..
  8. Kr ger K, Pfeifer F. Transcript analysis of the c-vac region and differential synthesis of the two regulatory gas vesicle proteins GvpD and GvpE in Halobacterium salinarium PHH4. J Bacteriol. 1996;178:4012-9 pubmed
    ..Such RNAs occurred during early stationary growth when the cGvpD protein level decreased and may possibly inhibit the translation of the c-gvpD mRNA...
  9. Fitter J, Ernst O, Hauss T, Lechner R, Hofmann K, Dencher N. Molecular motions and hydration of purple membranes and disk membranes studied by neutron scattering. Eur Biophys J. 1998;27:638-45 pubmed
    ..From these studies the interaction of solvent molecules with the surface of the protein-lipid complex appears to be qualitatively similar for both types of membranes...
  10. Offner S, Ziese U, Wanner G, Typke D, Pfeifer F. Structural characteristics of halobacterial gas vesicles. Microbiology. 1998;144 ( Pt 5):1331-42 pubmed
    ..Comparison of projections of model helices with the moiré pattern seen on the cylindrical part of the gas vesicles provided evidence that the ribs formed a helix of low pitch and not a stack of hoops...
  11. Krah M, Marwan W, Verm glio A, Oesterhelt D. Phototaxis of Halobacterium salinarium requires a signalling complex of sensory rhodopsin I and its methyl-accepting transducer HtrI. EMBO J. 1994;13:2150-5 pubmed
    ..It is concluded that SRI and HtrI form a stable complex in the cell membrane that signals to the flagellar motor and defines absorbance maximum, photocycling rate and photochemical efficiency of SRI...
  12. Bohm G, Jaenicke R. Relevance of sequence statistics for the properties of extremophilic proteins. Int J Pept Protein Res. 1994;43:97-106 pubmed
    ..Again, 'traffic rules of stabilization', in terms of amino acid changes in going from mesophilic to thermophilic proteins, cannot be given. ..
  13. Rudolph J, Oesterhelt D. Chemotaxis and phototaxis require a CheA histidine kinase in the archaeon Halobacterium salinarium. EMBO J. 1995;14:667-73 pubmed
    ..This indicates that CheAH.s. plays a crucial role in chemical and light signal integration, presumably interacting with at least two phototransducers and a number of chemoreceptors...
  14. Havelka W, Henderson R, Oesterhelt D. Three-dimensional structure of halorhodopsin at 7 A resolution. J Mol Biol. 1995;247:726-38 pubmed publisher
  15. Rudolph J, Tolliday N, Schmitt C, Schuster S, Oesterhelt D. Phosphorylation in halobacterial signal transduction. EMBO J. 1995;14:4249-57 pubmed
    ..The mechanism of chemo- and phototactic signal transduction in the Archaeon H.salinarium, therefore, is similar to the two-component signaling system known from chemotaxis in the eubacterium E.coli...
  16. Köpke A, Wittmann Liebold B. Sequence of the gene for ribosomal protein L23 from the archaebacterium Methanococcus vannielii. FEBS Lett. 1988;239:313-8 pubmed
    ..Interestingly, the secondary structures of the proteins as predicted by computer programs are more conserved than the primary structures. ..
  17. Kr mer W, Arndt E. Halobacterial S9 operon. Three ribosomal protein genes are cotranscribed with genes encoding a tRNA(Leu), the enolase, and a putative membrane protein in the archaebacterium Haloarcula (Halobacterium) marismortui. J Biol Chem. 1991;266:24573-9 pubmed
    ..The C-terminal part of the OrfMSG protein shows a significant similarity to the vertebrate laminin receptor protein...
  18. Jahn O, Hartmann R, Boeckh T, Erdmann V. Comparative analysis of ribosomal protein L5 sequences from bacteria of the genus Thermus. Biochimie. 1991;73:669-78 pubmed
    ..The occurrence of conserved sequence elements in 5S rRNA binding proteins and ribosomal proteins in general is discussed in terms of evolution and function. ..