Experts and Doctors on germ cells in Denmark
Topic: germ cells
Gjerstorff M, Harkness L, Kassem M, Frandsen U, Nielsen O, Lutterodt M, et al
. Distinct GAGE and MAGE-A expression during early human development indicate specific roles in lineage differentiation. Hum Reprod. 2008;23:2194-201 pubmed publisher
..Our results show that CTAs, in addition to their role in germ cells, may be involved in early development of various types of somatic cells, and suggest that they are implicated in specific differentiation processes. ..
Oestrup O, Hall V, Petkov S, Wolf X, Hyldig S, Hyttel P. From zygote to implantation: morphological and molecular dynamics during embryo development in the pig. Reprod Domest Anim. 2009;44 Suppl 3:39-49 pubmed publisher
..e. the primordial germ cells. The latter remain pluripotent for a period and may be isolated and cultured as embryonic germ cells in vitro. ..
Lasonder E, Ishihama Y, Andersen J, Vermunt A, Pain A, Sauerwein R, et al
. Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry. Nature. 2002;419:537-42 pubmed
..We also report a set of peptides with significant matches in the parasite genome but not in the protein set predicted by computational methods. ..
Vejlsted M, Offenberg H, Thorup F, Maddox Hyttel P. Confinement and clearance of OCT4 in the porcine embryo at stereomicroscopically defined stages around gastrulation. Mol Reprod Dev. 2006;73:709-18 pubmed
..As in the mouse, PGCs showed onset of c-kit expression when located in extraembryonal compartments. They appeared to follow the endoderm during extraembryonal allocation and the mesoderm on return to the genital ridge. ..
Gjerstorff M, Kock K, Nielsen O, Ditzel H. MAGE-A1, GAGE and NY-ESO-1 cancer/testis antigen expression during human gonadal development. Hum Reprod. 2007;22:953-60 pubmed
..The recognition of differential cellular expression of GAGE, MAGE-A1, NY-ESO-1 and OCT4 may help define biologically distinct germ cell subpopulations. ..
Rajpert De Meyts E, Hoei Hansen C. From gonocytes to testicular cancer: the role of impaired gonadal development. Ann N Y Acad Sci. 2007;1120:168-80 pubmed publisher
..The effects of environmental factors are likely modulated by genomic variation (polymorphisms), thus explaining the individual susceptibility and population-level differences in the incidence of testicular cancer...
Almstrup K, Nielsen J, Mlynarska O, Jansen M, Jørgensen A, Skakkebæk N, et al
. Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells. Br J Cancer. 2010;103:1269-76 pubmed publisher
..The CIS cell is a neoplastic counterpart of foetal germ cells. During their development, foetal germ cells undergo extensive and essential epigenetic modifications, but little is known about epigenetic patterns in CIS cells...
Boisen A, SHIPLEY T, Jackson P, Wallin H, Nellemann C, Vogel U, et al
. In utero exposure to nanosized carbon black (Printex90) does not induce tandem repeat mutations in female murine germ cells. Reprod Toxicol. 2013;41:45-8 pubmed publisher
..ESTR mutation rates in CB-exposed F2 female offspring were not statistically different from those of F2 female control offspring. ..
Morthorst T, Olsen A. Cell-nonautonomous inhibition of radiation-induced apoptosis by dynein light chain 1 in Caenorhabditis elegans. Cell Death Dis. 2013;4:e799 pubmed publisher
..Our results strengthen the notion of a highly dynamic communication between somatic cells and germ cells in regulating the apoptotic process. ..