Experts and Doctors on escherichia coli in Sweden


Locale: Sweden
Topic: escherichia coli

Top Publications

  1. Faxén M, Plumbridge J, Isaksson L. Codon choice and potential complementarity between mRNA downstream of the initiation codon and bases 1471-1480 in 16S ribosomal RNA affects expression of glnS. Nucleic Acids Res. 1991;19:5247-51 pubmed
    ..We also give evidence that supports the idea that the presence of rare codons near the beginning of the mRNA can affect expression. ..
  2. Saha S, Hagg rd Ljungquist E, Nordstr m K. The cox protein of bacteriophage P2 inhibits the formation of the repressor protein and autoregulates the early operon. EMBO J. 1987;6:3191-9 pubmed
  3. Lindahl M, Tabak S, Cseke L, Pichersky E, Andersson B, Adam Z. Identification, characterization, and molecular cloning of a homologue of the bacterial FtsH protease in chloroplasts of higher plants. J Biol Chem. 1996;271:29329-34 pubmed
    ..The trans-bilayer orientation and lateral location of the FtsH protein in the thylakoid membrane suggest its involvement in the degradation of both soluble stromal proteins and newly inserted or turning-over thylakoid proteins. ..
  4. Jemth P, Mannervik B. Kinetic characterization of recombinant human glutathione transferase T1-1, a polymorphic detoxication enzyme. Arch Biochem Biophys. 1997;348:247-54 pubmed
    ..One of these differences causes a change in the deduced amino acid sequence and involves the nucleotide triplet encoding amino acid 126, which was determined as GAG (Glu), instead of the published GGG (Gly). ..
  5. Karlsson E, Dahlberg L, Torto N, Gorton L, Holst O. Enzymatic specificity and hydrolysis pattern of the catalytic domain of the xylanase Xynl from Rhodothermus marinus. J Biotechnol. 1998;60:23-35 pubmed
    ..The enzyme was inactive on xylobiose, xylotriose and on the soluble fraction from oat spelt xylan. The R. marinus xylanase is shown to have a strong preference for internal linkages and is therefore classified as an endo-xylanase. ..
  6. Maisnier Patin S, Nordstrom K, DasGupta S. RecA-mediated rescue of Escherichia coli strains with replication forks arrested at the terminus. J Bacteriol. 2001;183:6065-73 pubmed
  7. Urbonavicius J, Stahl G, Durand J, Ben Salem S, Qian Q, Farabaugh P, et al. Transfer RNA modifications that alter +1 frameshifting in general fail to affect -1 frameshifting. RNA. 2003;9:760-8 pubmed
    ..Possible mechanisms explaining these results are discussed...
  8. Turunen M, Olsson J, Dallner G. Metabolism and function of coenzyme Q. Biochim Biophys Acta. 2004;1660:171-99 pubmed
    ..In this case the extent of disturbances is dependent on the localization and the modified distribution of the lipid at cellular and membrane levels. ..
  9. Zhao J, Jin S, Wieslander L. CRM1 and Ran are present but a NES-CRM1-RanGTP complex is not required in Balbiani ring mRNP particles from the gene to the cytoplasm. J Cell Sci. 2004;117:1553-66 pubmed
    ..Our results therefore suggest that several export receptors associate with BR mRNP and that these receptors have redundant functions in the nuclear export of BR mRNP. ..

More Information

Publications289 found, 100 shown here

  1. Aberg V, Fällman E, Axner O, Uhlin B, Hultgren S, Almqvist F. Pilicides regulate pili expression in E. coli without affecting the functional properties of the pilus rod. Mol Biosyst. 2007;3:214-8 pubmed
    ..The presented results establish a potential use of pilicides as chemical tools to study important biological processes e.g. adhesion, pilus biogenesis and the role of pili in infections and biofilm formation. ..
  2. Björnham O, Axner O. Multipili attachment of bacteria with helixlike pili exposed to stress. J Chem Phys. 2009;130:235102 pubmed publisher
    ..Even though the results presented in this work apply quantitatively to one type of pilus, they are assumed to apply qualitatively to all helixlike pili systems expressing slip bonds. ..
  3. Skoog K, Daley D. The Escherichia coli cell division protein ZipA forms homodimers prior to association with FtsZ. Biochemistry. 2012;51:1407-15 pubmed publisher
    ..This observation rules out the possibility that FtsZ polymers mediate the ZipA self-interaction. Given this observation, it is possible that a certain population of ZipA is recruited to the division septum in a homodimeric form. ..
  4. Nystrom T, Larsson C, Gustafsson L. Bacterial defense against aging: role of the Escherichia coli ArcA regulator in gene expression, readjusted energy flux and survival during stasis. EMBO J. 1996;15:3219-28 pubmed
  5. Eriksson M, Nielsen P, Good L. Cell permeabilization and uptake of antisense peptide-peptide nucleic acid (PNA) into Escherichia coli. J Biol Chem. 2002;277:7144-7 pubmed
    ..The enhanced cell-permeation properties of peptide-PNAs can explain their potent antisense activity, and the results indicate an unanticipated synergy between the peptide and PNA components. ..
  6. Johansson L, Chen C, Thorell J, Fredriksson A, Stone Elander S, Gafvelin G, et al. Exploiting the 21st amino acid-purifying and labeling proteins by selenolate targeting. Nat Methods. 2004;1:61-6 pubmed
    ..The results presented here thus show how a wide range of biotechnological applications can be developed starting from the insertion of selenocysteine into proteins. ..
  7. Tomenius H, Pernestig A, Méndez Catalá C, Georgellis D, Normark S, Melefors O. Genetic and functional characterization of the Escherichia coli BarA-UvrY two-component system: point mutations in the HAMP linker of the BarA sensor give a dominant-negative phenotype. J Bacteriol. 2005;187:7317-24 pubmed
    ..This also means that a tripartite sensor can be arranged as a dimer even in the dephosphorylating mode. ..
  8. Bernardo L, Johansson L, Solera D, Skarfstad E, Shingler V. The guanosine tetraphosphate (ppGpp) alarmone, DksA and promoter affinity for RNA polymerase in regulation of sigma-dependent transcription. Mol Microbiol. 2006;60:749-64 pubmed
  9. Sundstr m L, Roy P, Sk ld O. Site-specific insertion of three structural gene cassettes in transposon Tn7. J Bacteriol. 1991;173:3025-8 pubmed
    ..The surroundings of all three resistance genes indicated site-specific insertion of genetic cassettes...
  10. Kondo K, Kai M, Setoguchi Y, Eggertsen G, Sjoblom P, Setoguchi T, et al. Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta-reductase and substrate specificity of the expressed enzyme. Eur J Biochem. 1994;219:357-63 pubmed
    ..The substrate specificity of the human enzyme is considerably narrower than that of the rat enzyme, and the enzyme seems to be more important for bile acid biosynthesis than for metabolism of steroid hormones. ..
  11. Andersson A, Schneider G, Lindqvist Y. Purification and preliminary X-ray crystallographic studies of recombinant L-ribulose-5-phosphate 4-epimerase from Escherichia coli. Protein Sci. 1995;4:1648-50 pubmed
    ..8 A and c = 281.4 A and diffract to at least 2.2 A resolution. Density measurements of these crystals are consistent with eight subunits in the asymmetric unit. ..
  12. Meuller J, Hu X, Bunthof C, Olausson T, Rydstrom J. Identification of an aspartic acid residue in the beta subunit which is essential for catalysis and proton pumping by transhydrogenase from Escherichia coli. Biochim Biophys Acta. 1996;1273:191-4 pubmed
    ..It is proposed that betaAsp 392 together with th previously identified betaHis91 form part of a proton wire in transhydrogenase. ..
  13. Johansson J, Dagberg B, Richet E, Uhlin B. H-NS and StpA proteins stimulate expression of the maltose regulon in Escherichia coli. J Bacteriol. 1998;180:6117-25 pubmed
    ..Our results suggest that the H-NS and StpA proteins stimulate MalT translation and hence play a positive role in the control of the maltose regulon...
  14. Saaf A, Johansson M, Wallin E, von Heijne G. Divergent evolution of membrane protein topology: the Escherichia coli RnfA and RnfE homologues. Proc Natl Acad Sci U S A. 1999;96:8540-4 pubmed
    ..This example of divergent evolution of membrane protein topology suggests that a complete inversion of membrane topology is possible with relatively few mutational changes even for proteins with multiple transmembrane segments. ..
  15. Bouadloun F, Donner D, Kurland C. Codon-specific missense errors in vivo. EMBO J. 1983;2:1351-6 pubmed
    ..coli ribosomal protein S6 is 3-4 x 10(-3) for wild-type bacteria, decreases to 6 x 10(-4) in streptomycin-resistant bacteria and is elevated to nearly 10(-2) in Ram bacteria. ..
  16. Saaf A, Baars L, von Heijne G. The internal repeats in the Na+/Ca2+ exchanger-related Escherichia coli protein YrbG have opposite membrane topologies. J Biol Chem. 2001;276:18905-7 pubmed
    ..This has implications for our understanding of the function of Na(+)/Ca(2+) exchangers and provides an example of "divergent" evolution of membrane protein topology. ..
  17. Matsson M, Hederstedt L. The carboxin-binding site on Paracoccus denitrificans succinate:quinone reductase identified by mutations. J Bioenerg Biomembr. 2001;33:99-105 pubmed
    ..The block would be either by direct exclusion of ubiquinone from the active site or by occlusion of a pore that leads to the active site...
  18. Lövgren J, Wikström P. Hybrid protein between ribosomal protein S16 and RimM of Escherichia coli retains the ribosome maturation function of both proteins. J Bacteriol. 2001;183:5352-7 pubmed
    ..Thus, the S16-RimM hybrid protein seems capable of carrying out the important functions that native S16 and RimM have in ribosome biogenesis. ..
  19. Johansson C, Pedersen A, Karlsson B, Rydström J. Redox-sensitive loops D and E regulate NADP(H) binding in domain III and domain I-domain III interactions in proton-translocating Escherichia coli transhydrogenase. Eur J Biochem. 2002;269:4505-15 pubmed
    ..Most domain III mutants also showed a decreased affinity for domain I. The results support an important and regulatory role of loops D and E in the binding of NADP(H) as well as in the interaction between domain I and domain III. ..
  20. Carnrot C, Wehelie R, Eriksson S, Bölske G, Wang L. Molecular characterization of thymidine kinase from Ureaplasma urealyticum: nucleoside analogues as potent inhibitors of mycoplasma growth. Mol Microbiol. 2003;50:771-80 pubmed
  21. Lovmar M, Tenson T, Ehrenberg M. Kinetics of macrolide action: the josamycin and erythromycin cases. J Biol Chem. 2004;279:53506-15 pubmed
  22. Birgander P, Bug S, Kasrayan A, Dahlroth S, Westman M, Gordon E, et al. Nucleotide-dependent formation of catalytically competent dimers from engineered monomeric ribonucleotide reductase protein R1. J Biol Chem. 2005;280:14997-5003 pubmed
  23. Karlsson F, Malmborg Hager A, Albrekt A, Borrebaeck C. Genome-wide comparison of phage M13-infected vs. uninfected Escherichia coli. Can J Microbiol. 2005;51:29-35 pubmed
    ..Thus, global transcriptional analysis and functional analysis revealed previously unknown host responses to filamentous phage infection...
  24. Ivanova N, Pavlov M, Ehrenberg M. tmRNA-induced release of messenger RNA from stalled ribosomes. J Mol Biol. 2005;350:897-905 pubmed
    ..The reduced rate of release in the former case was due to a persisting SD-anti SD interaction between mRNA and the ribosome. ..
  25. Giske C, Monnet D, Cars O, Carmeli Y. Clinical and economic impact of common multidrug-resistant gram-negative bacilli. Antimicrob Agents Chemother. 2008;52:813-21 pubmed
  26. Andersson M, Axner O, Almqvist F, Uhlin B, Fällman E. Physical properties of biopolymers assessed by optical tweezers: analysis of folding and refolding of bacterial pili. Chemphyschem. 2008;9:221-35 pubmed publisher
    ..The information retrieved is also compared with that obtained by atomic force microscopy. ..
  27. Bonnedahl J, Drobni P, Johansson A, Hernandez J, Melhus A, Stedt J, et al. Characterization, and comparison, of human clinical and black-headed gull (Larus ridibundus) extended-spectrum beta-lactamase-producing bacterial isolates from Kalmar, on the southeast coast of Sweden. J Antimicrob Chemother. 2010;65:1939-44 pubmed publisher
    ..The results indicate that a potential for transfer between the human population and environment exists even in countries with a low level of antibiotic resistance. ..
  28. Nowrouzian F, Oswald E. Escherichia coli strains with the capacity for long-term persistence in the bowel microbiota carry the potentially genotoxic pks island. Microb Pathog. 2012;53:180-2 pubmed publisher
    ..Long-term persistence in the colon of pks island-containing E. coli strains may be associated with the induction of genomic mutations in the host intestine. ..
  29. Clementz T. The gene coding for 3-deoxy-manno-octulosonic acid transferase and the rfaQ gene are transcribed from divergently arranged promoters in Escherichia coli. J Bacteriol. 1992;174:7750-6 pubmed
  30. Hughes D, Buckingham R. The nucleotide sequence of rpsL and its flanking regions in Salmonella typhimurium. Gene. 1991;104:123-4 pubmed
    ..More surprisingly, the noncoding sequences surrounding the gene are also conserved at the 98% level, suggesting that they too are functionally important. ..
  31. Rydstrom J, Hu X, Fjellström O, Meuller J, Zhang J, Johansson C, et al. Domains, specific residues and conformational states involved in hydride ion transfer and proton pumping by nicotinamide nucleotide transhydrogenase from Escherichia coli. Biochim Biophys Acta. 1998;1365:10-6 pubmed
    ..coli and Rhodospirillum rubrum at hand, the overall aim of the transhydrogenase research, the understanding of the conformationally driven proton pumping mechanism, is within reach. ..
  32. Godaly G, Frendeus B, Proudfoot A, Svensson M, Klemm P, Svanborg C. Role of fimbriae-mediated adherence for neutrophil migration across Escherichia coli-infected epithelial cell layers. Mol Microbiol. 1998;30:725-35 pubmed
    ..Epithelial chemokine production provides a molecular link between the fimbriated bacteria that adhere to epithelial cells and tissue inflammation. ..
  33. Bergkvist A, Johansson C, Johansson T, Rydstrom J, Karlsson B. Interactions of the NADP(H)-binding domain III of proton-translocating transhydrogenase from escherichia coli with NADP(H) and the NAD(H)-binding domain I studied by NMR and site-directed mutagenesis. Biochemistry. 2000;39:12595-605 pubmed
    ..Finally, by combining the above conclusions with information obtained by a further characterization of previously constructed mutants, the implications of the findings were considered in a mechanistic context. ..
  34. L vgren J, Wikstr m P. The rlmB gene is essential for formation of Gm2251 in 23S rRNA but not for ribosome maturation in Escherichia coli. J Bacteriol. 2001;183:6957-60 pubmed publisher
    ..However, a DeltarlmB mutant did not show any ribosome assembly defects and was not outgrown by a wild-type strain even after 120 cell mass doublings. Thus, RlmB has no important role in ribosome assembly or function in E. coli...
  35. Oscarsson J, Westermark M, Beutin L, Uhlin B. The bacteriophage-associated ehly1 and ehly2 determinants from Escherichia coli O26:H- strains do not encode enterohemolysins per se but cause release of the ClyA cytolysin. Int J Med Microbiol. 2002;291:625-31 pubmed
    ..Taken together, our findings support a model where Ehlyl and Ehly2 cause a hemolyric phenotype on blood agar as a result of their lytic and lethal effects on the bacterial hosts. ..
  36. Backhed F, Meijer L, Normark S, Richter Dahlfors A. TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14. Cell Microbiol. 2002;4:493-501 pubmed
    ..Collectively, our findings strengthen the role for bladder epithelial cells as important players in the innate immune system within the urinary tract. ..
  37. Wai S, Lindmark B, Söderblom T, Takade A, Westermark M, Oscarsson J, et al. Vesicle-mediated export and assembly of pore-forming oligomers of the enterobacterial ClyA cytotoxin. Cell. 2003;115:25-35 pubmed
    ..The results define a vesicle-mediated transport mechanism in bacteria, and our findings show that the localization of proteins to OMVs directly may contribute to the activation and delivery of pathogenic effector proteins. ..
  38. Zhao Q, Ofverstedt L, Skoglund U, Isaksson L. Morphological variation of individual Escherichia coli 50S ribosomal subunits in situ, as revealed by cryo-electron tomography. Exp Cell Res. 2004;300:190-201 pubmed
    ..In addition, gross morphological heterogeneity was observed in the reconstructions. Our results demonstrate a considerable structural variability among individual 50S subunits in the intracellular environment. ..
  39. Sandén A, Bostrom M, Markland K, Larsson G. Solubility and proteolysis of the Zb-MalE and Zb-MalE31 proteins during overproduction in Escherichia coli. Biotechnol Bioeng. 2005;90:239-47 pubmed
    ..At low IPTG concentrations (< or = 5 microM), this formation is almost abolished while at a comparatively high concentration (> or = 300 microM) 50% of the total product accumulated was in the form of inclusion bodies. ..
  40. Lovmar M, Nilsson K, Vimberg V, Tenson T, Nervall M, Ehrenberg M. The molecular mechanism of peptide-mediated erythromycin resistance. J Biol Chem. 2006;281:6742-50 pubmed
    ..These model predictions are compared with experimental observations from growing bacterial cultures, and excellent agreement is found between theoretical prediction and experimental observation. ..
  41. Berg V, Sellstedt M, Hedenström M, Pinkner J, Hultgren S, Almqvist F. Design, synthesis and evaluation of peptidomimetics based on substituted bicyclic 2-pyridones-targeting virulence of uropathogenic E. coli. Bioorg Med Chem. 2006;14:7563-81 pubmed
    ..The results suggest that the limited in vivo potencies of the analogues are either uptake/distribution related or due to loss in binding specificity. ..
  42. Jonsson A, Nordlund S. In vitro studies of the uridylylation of the three PII protein paralogs from Rhodospirillum rubrum: the transferase activity of R. rubrum GlnD is regulated by alpha-ketoglutarate and divalent cations but not by glutamine. J Bacteriol. 2007;189:3471-8 pubmed
    ..Furthermore, we show that the deuridylylation reaction is greatly stimulated by glutamine and that Mn(2+) is required...
  43. Eriksson H. Controlled release of preservatives using dealuminated zeolite Y. J Biochem Biophys Methods. 2008;70:1139-44 pubmed
    ..Together, these results demonstrate an interesting potential use of dealuminated zeolite Y containing adsorbed preservatives for preventing microbial growth in numerous applications in industry and clinical setting...
  44. Doan T, Carlsson A, Hamberg M, Bulow L, Stymne S, Olsson P. Functional expression of five Arabidopsis fatty acyl-CoA reductase genes in Escherichia coli. J Plant Physiol. 2009;166:787-96 pubmed publisher
    ..The five functional FAR enzymes yielded distinctly different compositions of fatty alcohols when expressed in E. coli, indicating that the different enzymes may be involved in the production of different types of alcohols in plant cells...
  45. Svensson L, Hult A, Stamps R, Angstrom J, Teneberg S, Storry J, et al. Forssman expression on human erythrocytes: biochemical and genetic evidence of a new histo-blood group system. Blood. 2013;121:1459-68 pubmed publisher
    ..Taken together, we provide the first conclusive description of Fs expression in normal human hematopoietic tissue and the basis of a new histo-blood group system in man, FORS...
  46. Byström A, von Gabain A, Björk G. Differentially expressed trmD ribosomal protein operon of Escherichia coli is transcribed as a single polycistronic mRNA species. J Mol Biol. 1989;208:575-86 pubmed
  47. Lindquist S, Galleni M, Lindberg F, Normark S. Signalling proteins in enterobacterial AmpC beta-lactamase regulation. Mol Microbiol. 1989;3:1091-102 pubmed
    ..Instead it is suggested that AmpD and AmpE sense the effect of beta-lactam action on peptidoglycan biosynthesis and relay this signal to AmpR. ..
  48. Davydova N, Gryaznova O, Mashchenko O, Vysotskaya V, Jonsson B, Al Karadaghi S, et al. Ribosomal protein L22 from Thermus thermophilus: sequencing, overexpression and crystallisation. FEBS Lett. 1995;369:229-32 pubmed
    ..The recombinant protein was purified and crystallized. The crystals belong to the space group P2(1)2(1)2(1), with cell parameters of a = 32.6 A, b = 66.0 A, c = 67.8 A. ..
  49. Aslund F, Nordstrand K, Berndt K, Nikkola M, Bergman T, Ponstingl H, et al. Glutaredoxin-3 from Escherichia coli. Amino acid sequence, 1H AND 15N NMR assignments, and structural analysis. J Biol Chem. 1996;271:6736-45 pubmed
    ..Thus, despite an identical active site disulfide motif and a similar secondary structure and tertiary fold, Grx3 and Grx1 display large functional differences in in vitro protein disulfide oxido-reduction reactions. ..
  50. Throne Holst M, Thony Meyer L, Hederstedt L. Escherichia coli ccm in-frame deletion mutants can produce periplasmic cytochrome b but not cytochrome c. FEBS Lett. 1997;410:351-5 pubmed
    ..The ccm mutants produce cytochrome c-550 polypeptide, but not holocytochrome c. Taken together the results demonstrate that heme can be transported to the periplasm by a ccm-independent mechanism...
  51. Diez A, Farewell A, Nannmark U, Nystrom T. A mutation in the ftsK gene of Escherichia coli affects cell-cell separation, stationary-phase survival, stress adaptation, and expression of the gene encoding the stress protein UspA. J Bacteriol. 1997;179:5878-83 pubmed
    ..In contrast, the 5' end of the ftsK locus reported to complement ftsK44(Ts) phenotypes does not complement the phenotypes of the ftsK1::cat mutant. ..
  52. Brynnel E, Kurland C, Moran N, Andersson S. Evolutionary rates for tuf genes in endosymbionts of aphids. Mol Biol Evol. 1998;15:574-82 pubmed publisher
    ..We relate the observed differences in substitution frequencies to the absence of selective codon preferences in Buchnera and to the influence of Muller's ratchet on small asexual populations...
  53. Pedrajas J, Miranda Vizuete A, Javanmardy N, Gustafsson J, Spyrou G. Mitochondria of Saccharomyces cerevisiae contain one-conserved cysteine type peroxiredoxin with thioredoxin peroxidase activity. J Biol Chem. 2000;275:16296-301 pubmed
    ..Finally, exposure of null Prx1p mutant cells to oxidant conditions reveals an important role of the mitochondrial 1-Cys Prx in protection against oxidative stress. ..
  54. Bizouarn T, Fjellström O, Axelsson M, Korneenko T, Pestov N, Ivanova M, et al. Interactions between the soluble domain I of nicotinamide nucleotide transhydrogenase from Rhodospirillum rubrum and transhydrogenase from Escherichia coli. Effects on catalytic and H+-pumping activities. Eur J Biochem. 2000;267:3281-8 pubmed
    ..The reverse reaction and proton pumping showed a less pronounced change in pH dependence, demonstrating the regulatory role of domain II in these reactions. ..
  55. Johansson A, Mannervik B. Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones. J Biol Chem. 2001;276:33061-5 pubmed
    ..Based on this finding and the high activity with steroid substrates, we propose that GST A3-3 has evolved to catalyze isomerization reactions that contribute to the biosynthesis of steroid hormones. ..
  56. Xia L, Nordman T, Olsson J, Damdimopoulos A, Björkhem Bergman L, Nalvarte I, et al. The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress. J Biol Chem. 2003;278:2141-6 pubmed
    ..These data demonstrate that the selenoenzyme thioredoxin reductase is an important selenium-dependent ubiquinone reductase and can explain how selenium and ubiquinone, by a combined action, may protect the cell from oxidative damage. ..
  57. Fröderberg L, Houben E, Samuelson J, Chen M, Park S, Phillips G, et al. Versatility of inner membrane protein biogenesis in Escherichia coli. Mol Microbiol. 2003;47:1015-27 pubmed
    ..This indicates that IMP assembly is much more versatile than previously thought. ..
  58. Loinder K, Soderstrom M. An LXXLL motif in nuclear receptor corepressor mediates ligand-induced repression of the thyroid stimulating hormone-beta gene. J Steroid Biochem Mol Biol. 2005;97:322-7 pubmed
    ..We conclude that N-CoR and TRbeta cooperate in the regulation of the TSHbeta gene and that the ligand-dependent repression is mediated by the LXXLL motif in N-CoR. ..
  59. Savitski M, Nielsen M, Zubarev R. ModifiComb, a new proteomic tool for mapping substoichiometric post-translational modifications, finding novel types of modifications, and fingerprinting complex protein mixtures. Mol Cell Proteomics. 2006;5:935-48 pubmed
    ..000 Da (+C atom) incorporation into proline residues of peptides from proline-rich proteins found in human saliva. This modification is hypothesized to increase the known activity of the peptide. ..
  60. Shokri A, Veide A, Larsson G. RelA1 gene control of Escherichia coli lipid structure and cell performance during glucose limited fed-batch conditions. Appl Microbiol Biotechnol. 2006;73:464-73 pubmed
    ..These findings suggest that the relA1 gene has a defined, but ppGpp-independent, role in cells with a slowly decreasing metabolism of glucose to control the membrane morphology. ..
  61. Tobias J, Lebens M, Bolin I, Wiklund G, Svennerholm A. Construction of non-toxic Escherichia coli and Vibrio cholerae strains expressing high and immunogenic levels of enterotoxigenic E. coli colonization factor I fimbriae. Vaccine. 2008;26:743-52 pubmed publisher
    ..cholerae bacteria also induce strong CFA/I-specific serum IgA and IgG+M responses. We conclude that our constructs may be useful as candidate strains in an oral killed CF-ETEC vaccine. ..
  62. Persson E, Halle B. Cell water dynamics on multiple time scales. Proc Natl Acad Sci U S A. 2008;105:6266-71 pubmed publisher
    ..1%) of cell water exchanges from buried hydration sites on the microsecond time scale, consistent with the current understanding of protein hydration in solutions and crystals. ..
  63. Gordon E, Horsefield R, Swarts H, De Pont J, Neutze R, Snijder A. Effective high-throughput overproduction of membrane proteins in Escherichia coli. Protein Expr Purif. 2008;62:1-8 pubmed publisher
    ..In summary, we have designed a fast and efficient process for the production of medically relevant membrane proteins with a minimum number of screening parameters. ..
  64. Samuelsson T, Boren T, Johansen T, Lustig F. Properties of a transfer RNA lacking modified nucleosides. J Biol Chem. 1988;263:13692-9 pubmed
  65. Leijonmarck M, Liljas A. Structure of the C-terminal domain of the ribosomal protein L7/L12 from Escherichia coli at 1.7 A. J Mol Biol. 1987;195:555-79 pubmed
    ..The possibility that a 2-fold crystallographic axis is a molecular 2-fold axis is discussed. A patch of invariant residues on the surface of the dimer is probably involved in functional interactions with elongation factors...
  66. Fjellström O, Olausson T, Hu X, Källebring B, Ahmad S, Bragg P, et al. Three-dimensional structure prediction of the NAD binding site of proton-pumping transhydrogenase from Escherichia coli. Proteins. 1995;21:91-104 pubmed
  67. Persson K, Holm I, Heby O. Cloning and sequencing of an intronless mouse S-adenosylmethionine decarboxylase gene coding for a functional enzyme strongly expressed in the liver. J Biol Chem. 1995;270:5642-8 pubmed
    ..e. it catalyzed the decarboxylation of S-adenosylmethionine, and its specific activity was comparable with that of recombinant human AdoMetDC purified according to the same procedure. ..
  68. Svensson B, Hederstedt L. Bacillus subtilis CtaA is a heme-containing membrane protein involved in heme A biosynthesis. J Bacteriol. 1994;176:6663-71 pubmed
    ..Purified cytochrome isolated from both B. subtilis and E. coli membranes contained one polypeptide identified as CtaA by amino acid sequence analysis, about 0.2 mol of heme B per mol of polypeptide, and small amounts of heme A. ..
  69. Gustafsson C, Björk G. The tRNA-(m5U54)-methyltransferase of Escherichia coli is present in two forms in vivo, one of which is present as bound to tRNA and to a 3'-end fragment of 16 S rRNA. J Biol Chem. 1993;268:1326-31 pubmed
    ..However, the complex is not associated with the ribosome and the covalently bound RNA does not affect the tRNA methylating activity of the enzyme. ..
  70. Larsson A, Climent I, Nordlund P, Sahlin M, Sjoberg B. Structural and functional characterization of two mutated R2 proteins of Escherichia coli ribonucleotide reductase. Eur J Biochem. 1996;237:58-63 pubmed
    ..The results obtained with [F304]R2 indicate that structural changes in E. coli R2 in the vicinity of this helix distortion can influence the catalytic activity of the holoenzyme. ..
  71. Jordan A, Torrents E, Jeanthon C, Eliasson R, Hellman U, Wernstedt C, et al. B12-dependent ribonucleotide reductases from deeply rooted eubacteria are structurally related to the aerobic enzyme from Escherichia coli. Proc Natl Acad Sci U S A. 1997;94:13487-92 pubmed
    ..From the conservation of substrate- and effector-binding residues we propose that the B12-dependent class II enzymes contain a similar barrel...
  72. Johansson J, Uhlin B. Differential protease-mediated turnover of H-NS and StpA revealed by a mutation altering protein stability and stationary-phase survival of Escherichia coli. Proc Natl Acad Sci U S A. 1999;96:10776-81 pubmed
    ..We conclude that StpA, in contrast to H-NS, is present mainly in heteromeric form in E. coli. ..
  73. Liu T, Hagg rd Ljungquist E. The transcriptional switch of bacteriophage WPhi, a P2-related but heteroimmune coliphage. J Virol. 1999;73:9816-26 pubmed
    ..However, in contrast to P2 Cox, WPhi Cox is unable to activate the P4 Pll promoter...
  74. Diez A, Gustavsson N, Nystr m T. The universal stress protein A of Escherichia coli is required for resistance to DNA damaging agents and is regulated by a RecA/FtsK-dependent regulatory pathway. Mol Microbiol. 2000;36:1494-503 pubmed
    ..Moreover, the UV sensitivity of uspA mutants is enhanced in an additive manner by the ftsK1 mutation...
  75. Brodelius M, Lundgren A, Mercke P, Brodelius P. Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum. Eur J Biochem. 2002;269:3570-7 pubmed
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