Experts and Doctors on epsilonretrovirus in United States


Locale: United States
Topic: epsilonretrovirus

Top Publications

  1. Rovnak J, Quackenbush S. Walleye dermal sarcoma virus cyclin interacts with components of the mediator complex and the RNA polymerase II holoenzyme. J Virol. 2002;76:8031-9 pubmed
    ..These data suggest that WDSV OrfA functions through its interactions with these large, transcription complexes. Further investigations will clarify the role of the retrovirus cyclin in control of virus expression and transformation...
  2. Nudson W, Rovnak J, Buechner M, Quackenbush S. Walleye dermal sarcoma virus Orf C is targeted to the mitochondria. J Gen Virol. 2003;84:375-81 pubmed
    ..These results imply a functional role for WDSV Orf C in an alteration of mitochondrial function that results in apoptosis contributing to tumour regression...
  3. Holzschu D, Lapierre L, Lairmore M. Comparative pathogenesis of epsilonretroviruses. J Virol. 2003;77:12385-91 pubmed
  4. Hronek B, Meagher A, Rovnak J, Quackenbush S. Identification and characterization of cis-acting elements residing in the walleye dermal sarcoma virus promoter. J Virol. 2004;78:7590-601 pubmed
    ..EMSA utilizing the 15-bp repeat probe revealed that there are similarities of binding with W12 cell and developing-tumor nuclear extracts and that the binding differs from that observed with regressing-tumor nuclear extract...
  5. Rovnak J, Hronek B, Ryan S, Cai S, Quackenbush S. An activation domain within the walleye dermal sarcoma virus retroviral cyclin protein is essential for inhibition of the viral promoter. Virology. 2005;342:240-51 pubmed
    ..When fused to glutathione S-transferase, the rv-cyclin, its carboxy region, and the activation domain pull down components of transcription complexes from nuclear extracts, and pull down is lost by mutation of the activation domain...