Experts and Doctors on entomopoxvirinae in United States

Summary

Locale: United States
Topic: entomopoxvirinae

Top Publications

  1. Winter J, Hall R, Moyer R. The effect of inhibitors on the growth of the entomopoxvirus from Amsacta moorei in Lymantria dispar (gypsy moth) cells. Virology. 1995;211:462-73 pubmed
    ..Instead, in the presence of IBT, AmEPV enveloped, immature virions form devoid of a well-differentiated core, which unlike mature virions fail to insert into occlusion bodies...
  2. Hall R, Li Y, Feller J, Moyer R. The Amsacta moorei entomopoxvirus spheroidin gene is improperly transcribed in vertebrate poxviruses. Virology. 1996;224:427-36 pubmed
    ..Our results indicate that insect and vertebrate poxvirus promoters may not be universally interchangeable and imply that there are regulatory features of gene expression unique to the infected insect cell environment...
  3. Li Y, Hall R, Moyer R. Transient, nonlethal expression of genes in vertebrate cells by recombinant entomopoxviruses. J Virol. 1997;71:9557-62 pubmed
    ..Therefore, AmEPV may prove to be a highly efficient, nontoxic method of gene delivery into vertebrate cells for transient gene expression...
  4. Bawden A, Glassberg K, Diggans J, Shaw R, Farmerie W, Moyer R. Complete genomic sequence of the Amsacta moorei entomopoxvirus: analysis and comparison with other poxviruses. Virology. 2000;274:120-39 pubmed
    ..The complete genomic sequence of AmEPV paves the way for an understanding and comparison of the molecular properties and pathogenesis between the entomopoxviruses of insects and the more intensively studied vertebrate poxviruses...
  5. Mwaengo D, Lawrence P. A putative DNA helicase and novel oligoribonuclease in the Diachasmimorpha longicaudata entomopoxvirus (DlEPV). Arch Virol. 2003;148:1431-44 pubmed
    ..These results support earlier reports that DlEPV is a member of the sub-family Entomopoxvirinae, most likely in Group C, and is the first symbiotic EPV described to date from a parasitic wasp...
  6. Becker M, Greenleaf W, Ostrov D, Moyer R. Amsacta moorei entomopoxvirus expresses an active superoxide dismutase. J Virol. 2004;78:10265-75 pubmed
    ..Therefore, AMVSOD is the first example of an active poxvirus SOD...
  7. Lawrence P. Purification and partial characterization of an entomopoxvirus (DLEPV) from a parasitic wasp of tephritid fruit flies. J Insect Sci. 2002;2:10 pubmed
    ..Unlike other EPVs, DlEPV does not express the spheroidin protein. Since it also replicates in both the wasp and fly, members of two different insect Orders, DlEPV may represent a new EPV Group, or a subgroup of the Group C viruses...
  8. Li Q, Liston P, Moyer R. Functional analysis of the inhibitor of apoptosis (iap) gene carried by the entomopoxvirus of Amsacta moorei. J Virol. 2005;79:2335-45 pubmed
    ..Our results indicate that while the AMViap gene was active in controlling apoptosis through the intrinsic pathway, the virus likely encodes additional proteins that also regulate apoptosis...
  9. Li Q, Liston P, Schokman N, Ho J, Moyer R. Amsacta moorei Entomopoxvirus inhibitor of apoptosis suppresses cell death by binding Grim and Hid. J Virol. 2005;79:3684-91 pubmed
    ..Both Grim and Hid were demonstrated to interact with AMV-IAP in vivo, and Grim- or Hid-induced cell death was suppressed when AMV-IAP was coexpressed...

More Information

Publications14

  1. Hashimoto Y, Lawrence P. Comparative analysis of selected genes from Diachasmimorpha longicaudata entomopoxvirus and other poxviruses. J Insect Physiol. 2005;51:207-20 pubmed
  2. Lawrence P. Morphogenesis and cytopathic effects of the Diachasmimorpha longicaudata entomopoxvirus in host haemocytes. J Insect Physiol. 2005;51:221-33 pubmed
    ..These data indicate that DlEPV disrupts the normal function of host haemocytes, thereby insuring the successful development of D. longicaudata offspring and as such should be regarded as a symbiont of the wasp...
  3. Means J, Penabaz T, Clem R. Identification and functional characterization of AMVp33, a novel homolog of the baculovirus caspase inhibitor p35 found in Amsacta moorei entomopoxvirus. Virology. 2007;358:436-47 pubmed
    ..Thus, AMVp33 encodes a caspase inhibitor similar to baculovirus P35 with a preference for effector caspases. This is the first report of a p35 homolog from any viral or cellular genome outside of the baculovirus family...
  4. Becker M, Todd T, Moyer R. An Amsacta moorei entomopoxvirus ortholog of the poly(A) polymerase small subunit exhibits methyltransferase activity and is non-essential for virus growth. Virology. 2008;375:624-36 pubmed publisher
    ..No physical association was found between any of the putative AMEV PAP subunits. We therefore propose that mRNA polyadenylation does not require interactions between these three proteins...
  5. Lawrence P, Dillard B. A homolog of the vaccinia virus D13L rifampicin resistance gene is in the entomopoxvirus of the parasitic wasp, Diachasmimorpha longicaudata. J Insect Sci. 2008;8:8 pubmed publisher
    ..htm) until its relationship to other diptera-infecting (Gammaentomopoxvirus or Genus C) entomopoxviruses can be verified. The GenBank accession number for the nucleotide sequence data reported in this paper is EF541029...