Experts and Doctors on endothelial cells in France


Locale: France
Topic: endothelial cells

Top Publications

  1. Juin A, Planus E, Guillemot F, Horáková P, Albiges Rizo C, Genot E, et al. Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells. Biol Cell. 2013;105:46-57 pubmed publisher
    ..Our results show that microvascular endothelial cells are able to form podosomes without specific stimulation. Our data suggest that the major determinant of podosome induction in these cells is substrate rigidity. ..
  2. Bonnaud S, Niaudet C, Pottier G, Gaugler M, Millour J, Barbet J, et al. Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage-induced mitotic death. Cancer Res. 2007;67:1803-11 pubmed
  3. Boyer L, Doye A, Rolando M, Flatau G, Munro P, Gounon P, et al. Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors. J Cell Biol. 2006;173:809-19 pubmed
    ..Intoxication of endothelial monolayers by EDIN produces a loss of barrier function and provides direct access of the endothelium basement membrane to S. aureus. ..
  4. Crestani B, Marchand Adam S, Quesnel C, Plantier L, Borensztajn K, Marchal J, et al. Hepatocyte growth factor and lung fibrosis. Proc Am Thorac Soc. 2012;9:158-63 pubmed publisher
    ..In vivo, HGF has antifibrotic properties demonstrated in experimental models of lung, kidney, heart, skin, and liver fibrosis. Hence, the modulation of HGF may be an attractive target for the treatment of lung fibrosis. ..
  5. Sgarioto M, Vigneron P, Patterson J, Malherbe F, Nagel M, Egles C. Collagen type I together with fibronectin provide a better support for endothelialization. C R Biol. 2012;335:520-8 pubmed publisher
  6. Lyck R, Lécuyer M, Abadier M, Wyss C, Matti C, Rosito M, et al. ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood-brain barrier. J Cereb Blood Flow Metab. 2017;37:2894-2909 pubmed publisher
    ..Taken together, our study highlights the potential differences in the CNS expression of ALCAM in mouse and human and supports a prominent role for ALCAM in the multi-step extravasation of monocytes across the BBB. ..
  7. Belkheiri N, Bouguerne B, Bedos Belval F, Duran H, Bernis C, Salvayre R, et al. Synthesis and antioxidant activity evaluation of a syringic hydrazones family. Eur J Med Chem. 2010;45:3019-26 pubmed publisher
    ..In this report, we discuss about the synthesis of hydrazones and their dual biological role, antioxidant and carbonyl scavenger for further application in atherosclerosis. ..
  8. Tirand L, Frochot C, Vanderesse R, Thomas N, Trinquet E, Pinel S, et al. A peptide competing with VEGF165 binding on neuropilin-1 mediates targeting of a chlorin-type photosensitizer and potentiates its photodynamic activity in human endothelial cells. J Control Release. 2006;111:153-64 pubmed
    ..Taken together, our results demonstrate that TPC-Ahx-ATWLPPR is a much more potent photosensitizer in vitro than TPC, in NRP-1-expressing cells. Thus, it may efficiently potentiate the vascular effect of PDT in vivo. ..
  9. Middleton J, Americh L, Gayon R, Julien D, Mansat M, Mansat P, et al. A comparative study of endothelial cell markers expressed in chronically inflamed human tissues: MECA-79, Duffy antigen receptor for chemokines, von Willebrand factor, CD31, CD34, CD105 and CD146. J Pathol. 2005;206:260-8 pubmed
    ..However, they also localized to other cell types. For example, CD34 stained fibroblasts, CD146 was expressed by the pericytes and smooth muscle cells of vessel walls and CD31 and CD105 labelled a broad range of cell types. ..

More Information

Publications109 found, 100 shown here

  1. Tournadre A, Miossec P. Cytokine response in inflammatory myopathies. Curr Rheumatol Rep. 2007;9:286-90 pubmed
    ..Cytokines promote changes in muscle metabolism resulting in a self-sustaining inflammatory response. Accordingly, cytokines may represent new targets for therapies. ..
  2. Brambilla D, Nicolas J, Le Droumaguet B, Andrieux K, Marsaud V, Couraud P, et al. Design of fluorescently tagged poly(alkyl cyanoacrylate) nanoparticles for human brain endothelial cell imaging. Chem Commun (Camb). 2010;46:2602-4 pubmed publisher
  3. Fons P, Chabot S, Cartwright J, Lenfant F, L Faqihi F, Giustiniani J, et al. Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells. Blood. 2006;108:2608-15 pubmed
  4. Meghari S, Desnues B, Capo C, Grau G, Raoult D, Mege J. Coxiella burnetii stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever. Eur Cytokine Netw. 2006;17:253-9 pubmed
    ..We suggest that the overproduction of RANTES and MCP-1 secondary to the contact of PBMC with endothelium may perpetuate exaggerated inflammatory responses leading to inappropriate PBMC trafficking and to the pathogenesis of Q fever. ..
  5. Cortes M, Gibon J, Chanteloup N, Moulin Schouleur M, Gilot P, Germon P. Inactivation of ibeA and ibeT results in decreased expression of type 1 fimbriae in extraintestinal pathogenic Escherichia coli strain BEN2908. Infect Immun. 2008;76:4129-36 pubmed publisher
    ..We finally suggest a role for IbeA and IbeT in modulating the expression of type 1 fimbriae through an as yet unknown mechanism. ..
  6. Tirand L, Thomas N, Dodeller M, Dumas D, Frochot C, Maunit B, et al. Metabolic profile of a peptide-conjugated chlorin-type photosensitizer targeting neuropilin-1: an in vivo and in vitro study. Drug Metab Dispos. 2007;35:806-13 pubmed
    ..This study provides essential information for the choice of the time of activation of the photosensitizer (drug-light interval) not to be exceeded and for the future design of more stable molecules. ..
  7. Guillotin B, Bourget C, Remy Zolgadri M, Bareille R, Fernandez P, Conrad V, et al. Human primary endothelial cells stimulate human osteoprogenitor cell differentiation. Cell Physiol Biochem. 2004;14:325-32 pubmed
    ..These data seem to indicate that this cross talk between HOP and ECs, through gap junction communication constitutes an additional concept in cell differentiation control. ..
  8. Gouysse G, Frachon S, Hervieu V, Fiorentino M, D Errico A, Dumortier J, et al. Endothelial cell differentiation in hepatocellular adenomas: implications for histopathological diagnosis. J Hepatol. 2004;41:259-66 pubmed
    ..However, the vascular phenotypic heterogeneity observed in our study questions the potential relevance of endothelial cell immunophenotyping for the differential diagnosis between hepatocellular adenomas and well differentiated HCC. ..
  9. Miller F, Fenart L, Landry V, Coisne C, Cecchelli R, Dehouck M, et al. The MAP kinase pathway mediates transcytosis induced by TNF-alpha in an in vitro blood-brain barrier model. Eur J Neurosci. 2005;22:835-44 pubmed
    ..These data suggest that the MAPK pathway is involved in the transcytosis regulation in endothelial cells from an in vitro BBB model. ..
  10. Doulet N, Donnadieu E, Laran Chich M, Niedergang F, Nassif X, Couraud P, et al. Neisseria meningitidis infection of human endothelial cells interferes with leukocyte transmigration by preventing the formation of endothelial docking structures. J Cell Biol. 2006;173:627-37 pubmed
    ..meningitidis. These results highlight a novel strategy developed by a bacterial pathogen to hamper the host inflammatory response by interfering with leukocyte-endothelial cell interaction. ..
  11. Ramkhelawon B, Vilar J, Rivas D, Mees B, de Crom R, Tedgui A, et al. Shear stress regulates angiotensin type 1 receptor expression in endothelial cells. Circ Res. 2009;105:869-75 pubmed publisher
    ..Our results demonstrate that SS may convey some of its atheroprotective effects through downregulation of AT(1)R in endothelial cells. ..
  12. Guillabert Gourgues A, Jaspard Vinassa B, Bats M, Sewduth R, Franzl N, Peghaire C, et al. Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity-signaling pathway. Mol Biol Cell. 2016;27:941-53 pubmed publisher
    ..These data demonstrate that Kif26b, together with Dvl3/Daam1, initiates cell polarity through the control of PCP signaling pathway-dependent activation. ..
  13. Tournaire R, Simon M, Le Noble F, Eichmann A, England P, Pouyssegur J. A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor. EMBO Rep. 2004;5:262-7 pubmed
    ..It also represents a potent tool to dissect the molecular mechanisms involved in the Tie2 pathway. ..
  14. Ebrahimian T, Heymes C, You D, Blanc Brude O, Mees B, Waeckel L, et al. NADPH oxidase-derived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes. Am J Pathol. 2006;169:719-28 pubmed
    ..05). Thus, inhibition of NADPH oxidase-derived ROS overproduction improves the angiogenic and vasculogenic processes and restores postischemic neovascularization in type 1 diabetic mice. ..
  15. Bertin S, Mohsen Kanson T, Baque P, Gavelli A, Momier D, Anjuere F, et al. Tumor microenvironment modifications induced by soluble VEGF receptor expression in a rat liver metastasis model. Cancer Lett. 2010;298:264-72 pubmed publisher
    ..Altogether, these results suggest that VEGF trapping by sFLT-1 intratumoral expression results in reduced vascularization, tumor growth inhibition and modification of immune tumor microenvironment. ..
  16. Chabrot P, Fatimi A, Fraine P, Ouchchane L, Dauplat M, Rivard A, et al. Embolization and endothelial ablation with chitosan and sodium sotradecol sulfate: preliminary results in an animal model. J Endovasc Ther. 2012;19:439-49 pubmed publisher
    ..To investigate whether embolization with chitosan hydrogel (CH) with or without a sclerosant (sodium tetradecyl sulphate, STS) can induce chemical endothelial ablation and prevent endothelial recanalization in a rabbit model...
  17. Bertheuil N, Chaput B, Berger Müller S, Ménard C, Mourcin F, Watier E, et al. Liposuction Preserves the Morphological Integrity of the Microvascular Network: Flow Cytometry and Confocal Microscopy Evidence in a Controlled Study. Aesthet Surg J. 2016;36:609-18 pubmed publisher
    ..Indeed, a low percentage of endothelial cells was found in AT from liposuction and we confirm the persistence of microvessels in the tissue after liposuction. ..
  18. Cognasse F, Hamzeh Cognasse H, Laradi S, Chou M, Seghatchian J, Burnouf T, et al. The role of microparticles in inflammation and transfusion: A concise review. Transfus Apher Sci. 2015;53:159-67 pubmed publisher
    ..Microparticles originating from platelets, leukocytes, erythrocytes, and endothelial cells are associated with a variety of pathophysiological conditions. This review summarises the role of Microparticles in modulating inflammation. ..
  19. Gaugler M, Vereycken Holler V, Squiban C, Vandamme M, Vozenin Brotons M, Benderitter M. Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses. Radiat Res. 2005;163:479-87 pubmed
    ..Pravastatin exerts persistent anti-inflammatory and anti-thrombotic effects on irradiated endothelial cells. Statins may be considered in therapeutic strategies for the management of patients treated with radiation therapy. ..
  20. Jullienne B, Vigant F, Muth E, Chaligne R, Bouquet C, Giraudier S, et al. Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid. Gene Ther. 2009;16:1405-15 pubmed publisher
    ..Altogether, our results suggest that NGR-bearing Ad are valuable tools to realize the potential of this anti-angiogenic approach to anti-tumor therapy. ..
  21. Alhosin M, Anselm E, Rashid S, Kim J, Madeira S, Bronner C, et al. Redox-sensitive up-regulation of eNOS by purple grape juice in endothelial cells: role of PI3-kinase/Akt, p38 MAPK, JNK, FoxO1 and FoxO3a. PLoS ONE. 2013;8:e57883 pubmed publisher
  22. Zerr Fouineau M, Jourdain M, Boesch C, Hecker M, Bronner C, Schini Kerth V. Certain progestins prevent the enhancing effect of 17beta-estradiol on NO-mediated inhibition of platelet aggregation by endothelial cells. Arterioscler Thromb Vasc Biol. 2009;29:586-93 pubmed publisher
  23. Kissa K, Herbomel P. Blood stem cells emerge from aortic endothelium by a novel type of cell transition. Nature. 2010;464:112-5 pubmed publisher
  24. Pifferi F, Jouin M, Alessandri J, Haedke U, Roux F, Perriere N, et al. n-3 Fatty acids modulate brain glucose transport in endothelial cells of the blood-brain barrier. Prostaglandins Leukot Essent Fatty Acids. 2007;77:279-86 pubmed
    ..In conclusion, we suggest that n-3 PUFA can modulate the brain glucose transport in endothelial cells of the blood-brain barrier, possibly via changes in GLUT1 protein expression and activity. ..
  25. Derkaoui S, Avramoglou T, Barbaud C, Letourneur D. Synthesis and characterization of a new polysaccharide-graft-polymethacrylate copolymer for three-dimensional hybrid hydrogels. Biomacromolecules. 2008;9:3033-8 pubmed publisher
    ..In conclusion, this type of copolymer with hybrid properties of two biocompatible macromolecules could be of great interest as a 3D scaffold or for coating in biomedical applications. ..
  26. Devalliere J, Charreau B. The adaptor Lnk (SH2B3): an emerging regulator in vascular cells and a link between immune and inflammatory signaling. Biochem Pharmacol. 2011;82:1391-402 pubmed publisher
    ..Overall, these studies emphasize the importance of the Lnk adaptor molecule not only as prognostic marker but also as potential therapeutic target. ..
  27. Beyer S, Kelly R, Miquerol L. Inducible Cx40-Cre expression in the cardiac conduction system and arterial endothelial cells. Genesis. 2011;49:83-91 pubmed publisher
    ..Cx40(Cre) mice can therefore be used to direct inducible genetic modification in Cx40 expressing cells. ..
  28. Magnon C, Galaup A, Mullan B, Rouffiac V, Bouquet C, Bidart J, et al. Canstatin acts on endothelial and tumor cells via mitochondrial damage initiated through interaction with alphavbeta3 and alphavbeta5 integrins. Cancer Res. 2005;65:4353-61 pubmed
    ..Taken together, these results provide insights into how canstatin might exert its strong anticancer effect. ..
  29. Tozer S, Bonnin M, Relaix F, Di Savino S, Garcia Villalba P, Coumailleau P, et al. Involvement of vessels and PDGFB in muscle splitting during chick limb development. Development. 2007;134:2579-91 pubmed
    ..Finally, we propose that PDGFB promotes the production of extracellular matrix and attracts connective tissue cells to the future splitting site, allowing separation of the muscle masses during the splitting process. ..
  30. Bourges D, Meurens F, Berri M, Chevaleyre C, Zanello G, Levast B, et al. New insights into the dual recruitment of IgA+ B cells in the developing mammary gland. Mol Immunol. 2008;45:3354-62 pubmed publisher
    ..They support the existence of a functional link between entero- and upper respiratory surfaces and MG, thereby, conferring protection against aero-digestive pathogens in the newborn. ..
  31. Chanet A, Milenkovic D, Claude S, Maier J, Kamran Khan M, Rakotomanomana N, et al. Flavanone metabolites decrease monocyte adhesion to TNF-?-activated endothelial cells by modulating expression of atherosclerosis-related genes. Br J Nutr. 2013;110:587-98 pubmed publisher
    ..This provides a potential explanation for the vasculoprotective effects of flavanones. ..
  32. Spuul P, Chi P, Billottet C, Chou C, Génot E. Microfluidic devices for the study of actin cytoskeleton in constricted environments: Evidence for podosome formation in endothelial cells exposed to a confined slit. Methods. 2016;94:65-74 pubmed publisher
    ..The study demonstrates the suitability of this technological process for cost-effective fabrication of custom-made single-use chips for biological applications. ..
  33. Mairey E, Genovesio A, Donnadieu E, Bernard C, Jaubert F, Pinard E, et al. Cerebral microcirculation shear stress levels determine Neisseria meningitidis attachment sites along the blood-brain barrier. J Exp Med. 2006;203:1939-50 pubmed
    ..These results argue that the combined mechanical properties of neisserial adhesion and blood microcirculation target meningococci to transiently underperfused cerebral capillaries and thus determine disease development. ..
  34. Saint Pol J, Candela P, Boucau M, Fenart L, Gosselet F. Oxysterols decrease apical-to-basolateral transport of Aß peptides via an ABCB1-mediated process in an in vitro Blood-brain barrier model constituted of bovine brain capillary endothelial cells. Brain Res. 2013;1517:1-15 pubmed publisher
  35. Dif F, Djediat C, Alegria O, Demeneix B, Levi G. Transfection of multiple pulmonary cell types following intravenous injection of PEI-DNA in normal and CFTR mutant mice. J Gene Med. 2006;8:82-9 pubmed
    ..The results demonstrate that PEI-mediated gene delivery leads to transfection of epithelial cells beyond the endothelial barrier and show that this method can be used for lung gene delivery in CF fragile mutant mice. ..
  36. Belli P, Bellaton C, Durand J, Balleydier S, Milhau N, Mure M, et al. Fetal and neonatal exposure to the mycotoxin zearalenone induces phenotypic alterations in adult rat mammary gland. Food Chem Toxicol. 2010;48:2818-26 pubmed publisher
    ..The induction of phenotypic alterations by zearalenone administered in utero and in the neonatal period at doses as low as 0.2 ?g/kg suggests that zearalenone could contribute to the induction of breast endocrine disorders. ..
  37. Rosselin M, Abed N, Virlogeux Payant I, Bottreau E, Sizaret P, Velge P, et al. Heterogeneity of type III secretion system (T3SS)-1-independent entry mechanisms used by Salmonella Enteritidis to invade different cell types. Microbiology. 2011;157:839-47 pubmed publisher
    ..Overall, these data open new avenues for discovering new invasion mechanisms in Salmonella...
  38. Debdab M, Carreaux F, Renault S, Soundararajan M, Fedorov O, Filippakopoulos P, et al. Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing. J Med Chem. 2011;54:4172-86 pubmed publisher
    ..Leucettines may also be investigated as potential therapeutic drugs in Alzheimer's disease (AD) and in diseases involving abnormal pre-mRNA splicing. ..
  39. Le Goffic R, Arshad M, Rauch M, L Helgoualc h A, Delmas B, Piquet Pellorce C, et al. Infection with influenza virus induces IL-33 in murine lungs. Am J Respir Cell Mol Biol. 2011;45:1125-32 pubmed publisher
    ..In conclusion, our findings evidenced a profound expression of IL-33 in lungs during both in vivo and in vitro IAV infections, suggesting a role for IL-33 in virus-induced lung infections. ..
  40. Hudry Clergeon H, Stengel D, Ninio E, Vilgrain I. Platelet-activating factor increases VE-cadherin tyrosine phosphorylation in mouse endothelial cells and its association with the PtdIns3'-kinase. FASEB J. 2005;19:512-20 pubmed
    ..Physical association between PtdIns3'-kinase, serving as a docking protein, and VE-cadherin may thus provide an efficient mechanism for amplification and perpetuation of PAF-induced cellular activation. ..
  41. Hadri L, Pavoine C, Lipskaia L, Yacoubi S, Lompre A. Transcription of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase type 3 gene, ATP2A3, is regulated by the calcineurin/NFAT pathway in endothelial cells. Biochem J. 2006;394:27-33 pubmed
    ..By increasing the rate of Ca2+ sequestration, up-regulation of SERCA 3 counteracts the cytosolic increase in Ca2+ concentration. ..
  42. Borgne Sanchez A, Dupont S, Langonne A, Baux L, Lecoeur H, Chauvier D, et al. Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells. Cell Death Differ. 2007;14:422-35 pubmed
    ..Hence, this chimeric peptide constitutes the first example of a virus-derived mitochondriotoxic compound as a candidate to kill selectively tumor neo-endothelia. ..
  43. Tran Hung L, Mathieu S, About I. Role of human pulp fibroblasts in angiogenesis. J Dent Res. 2006;85:819-23 pubmed
    ..These results suggest that the pulp fibroblasts secrete angiogenic factors, which are necessary for complete pulp healing, particularly at the pulp injury site...
  44. de Souza J, Vindis C, Hansel B, Negre Salvayre A, Therond P, Serrano C, et al. Metabolic syndrome features small, apolipoprotein A-I-poor, triglyceride-rich HDL3 particles with defective anti-apoptotic activity. Atherosclerosis. 2008;197:84-94 pubmed
  45. Sanson M, Ingueneau C, Vindis C, Thiers J, Glock Y, Rousseau H, et al. Oxygen-regulated protein-150 prevents calcium homeostasis deregulation and apoptosis induced by oxidized LDL in vascular cells. Cell Death Differ. 2008;15:1255-65 pubmed publisher
    ..Finally, ORP150 is expressed in advanced atherosclerotic lesions, where it may locally participate to reduce the apoptotic effect of oxLDLs and the subsequent risk of plaque rupture. ..
  46. Lejmi E, Leconte L, Pedron Mazoyer S, Ropert S, Raoul W, Lavalette S, et al. Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B. Proc Natl Acad Sci U S A. 2008;105:12491-6 pubmed publisher
    ..Moreover, Netrin-4 overexpression delayed tumor angiogenesis in a model of s.c. xenograft. We propose that Netrin-4 acts as an antiangiogenic factor through binding to neogenin and recruitment of Unc5B. ..
  47. Imberty A, Varrot A. Microbial recognition of human cell surface glycoconjugates. Curr Opin Struct Biol. 2008;18:567-76 pubmed publisher
    ..They illustrate the tight specificity between tissue glycosylation and lectins. ..
  48. De Seranno S, d Anglemont de Tassigny X, Estrella C, Loyens A, Kasparov S, Leroy D, et al. Role of estradiol in the dynamic control of tanycyte plasticity mediated by vascular endothelial cells in the median eminence. Endocrinology. 2010;151:1760-72 pubmed publisher
    ..Taken together, our findings show that estradiol controls the dialog between endothelial cells and astroglia to regulate neuroglial plasticity in the neuroendocrine brain...
  49. Mazars R, Gonzalez de Peredo A, Cayrol C, Lavigne A, Vogel J, Ortega N, et al. The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias. J Biol Chem. 2010;285:13364-71 pubmed publisher
    ..Interestingly, our results also provide an unexpected link between DYT6 and DYT3 (X-linked dystonia-parkinsonism) dystonias because the gene encoding the THAP1/DYT6 protein partner OGT maps within the DYT3 critical region on Xq13.1. ..
  50. Quillard T, Devalliere J, Coupel S, Charreau B. Inflammation dysregulates Notch signaling in endothelial cells: implication of Notch2 and Notch4 to endothelial dysfunction. Biochem Pharmacol. 2010;80:2032-41 pubmed publisher
    ..Thus, here we provide evidence for a role of soluble mediators of inflammation (i.e. cytokines) in the regulation of Notch signaling and for the implication of a dysregulated Notch pathway to endothelial and vascular dysfunction. ..
  51. Chanet A, Milenkovic D, Deval C, Potier M, Constans J, Mazur A, et al. Naringin, the major grapefruit flavonoid, specifically affects atherosclerosis development in diet-induced hypercholesterolemia in mice. J Nutr Biochem. 2012;23:469-77 pubmed publisher
    ..In conclusion, this study revealed the antiatherogenic effect of NAR supplemented at a nutritionally achievable dose, specifically toward diet-induced atherosclerosis, and depicted its multitarget mode of action at the vascular level. ..
  52. Calligaris D, Manatschal C, Marcellin M, Villard C, Monsarrat B, Burlet Schiltz O, et al. Tyrosine-dependent capture of CAP-Gly domain-containing proteins in complex mixture by EB1 C-terminal peptidic probes. J Proteomics. 2012;75:3605-16 pubmed publisher
    ..Our peptidic probes represent valuable tools to detect changes induced in EB1-dependent +TIP networks by external cues such as growth factors and small molecules. ..
  53. Tavares J, Formaglio P, Thiberge S, Mordelet E, Van Rooijen N, Medvinsky A, et al. Role of host cell traversal by the malaria sporozoite during liver infection. J Exp Med. 2013;210:905-15 pubmed publisher
    ..By being involved in multiple steps of the sporozoite journey from the skin to the final hepatocyte, the parasite proteins mediating host CT emerge as ideal antibody targets for vaccination against the parasite...
  54. Camaré C, Augé N, Pucelle M, Saint Lèbes B, Grazide M, Nègre Salvayre A, et al. The neutral sphingomyelinase-2 is involved in angiogenic signaling triggered by oxidized LDL. Free Radic Biol Med. 2016;93:204-16 pubmed publisher
    ..In conclusion, low oxLDL concentration triggers sprouting angiogenesis that involves ROS-induced activation of the neutral sphingomyelinase-2/sphingosine kinase-1 pathway, and is effectively inhibited by GW4869. ..
  55. Boselli F, Steed E, Freund J, Vermot J. Anisotropic shear stress patterns predict the orientation of convergent tissue movements in the embryonic heart. Development. 2017;144:4322-4327 pubmed publisher
  56. Bernot D, Peiretti F, Canault M, Juhan Vague I, Nalbone G. Upregulation of TNF-alpha-induced ICAM-1 surface expression by adenylate cyclase-dependent pathway in human endothelial cells. J Cell Physiol. 2005;202:434-41 pubmed
    ..Combination of activation of gene transcription and membrane targeting may account for this augmentation. ..
  57. Lamerant N, Kieda C. Adhesion properties of adhesion-regulating molecule 1 protein on endothelial cells. FEBS J. 2005;272:1833-44 pubmed
    ..However, no cell surface expression of the protein was observed. These results suggest an indirect role of ARM-1 in adhesion rather than a direct role as an adhesion molecule itself. ..
  58. Wautier M, Khodabandehlou T, Le Devehat C, Wautier J. Modulation of RAGE expression influences the adhesion of red blood cells from diabetic patients. Clin Hemorheol Microcirc. 2006;35:379-86 pubmed
    ..Adrenaline-treated RBCs showed a transient increase in adhesion at low shear stresses. Inflammatory mediators or catecholamine amplifying diabetic RBC adhesion may aggravate endothelial cell damages. ..
  59. Smadja D, Bieche I, Silvestre J, Germain S, Cornet A, Laurendeau I, et al. Bone morphogenetic proteins 2 and 4 are selectively expressed by late outgrowth endothelial progenitor cells and promote neoangiogenesis. Arterioscler Thromb Vasc Biol. 2008;28:2137-43 pubmed publisher
    ..BMP2/4 are a marker of ECFCs and play a key role in ECFC commitment and outgrowth during neovascularization. ..
  60. Gosselet F, Candela P, Sevin E, Berezowski V, Cecchelli R, Fenart L. Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood-brain barrier: use of an in vitro model. Brain Res. 2009;1249:34-42 pubmed publisher
    ..Altogether, these results highlight the importance of glial input in the BBB transport phenotype for sterol homeostasis in the central nervous system, and confirm the importance of the BBB in this process...
  61. Candela P, Gosselet F, Miller F, Buee Scherrer V, Torpier G, Cecchelli R, et al. Physiological pathway for low-density lipoproteins across the blood-brain barrier: transcytosis through brain capillary endothelial cells in vitro. Endothelium. 2008;15:254-64 pubmed publisher
    ..These results could provide clues to physiological functions of caveolae-caveosome transcellular pathway in brain capillary ECs and may help in the rational design of more effective therapeutic drugs to the brain. ..
  62. Bardin N, Blot Chabaud M, Despoix N, Kebir A, Harhouri K, Arsanto J, et al. CD146 and its soluble form regulate monocyte transendothelial migration. Arterioscler Thromb Vasc Biol. 2009;29:746-53 pubmed publisher
    ..Our results demonstrate that CD146 is regulated by the inflammatory cytokine TNF and that CD146 and sCD146 are both involved in monocyte transendothelial migration during inflammation. ..
  63. Faye C, Moreau C, Chautard E, Jetne R, Fukai N, Ruggiero F, et al. Molecular interplay between endostatin, integrins, and heparan sulfate. J Biol Chem. 2009;284:22029-40 pubmed publisher
    ..5 nM). The direct binding between integrins and heparin/heparan sulfate might explain why both heparan sulfate and alpha5beta1 integrin are required for the localization of endostatin in endothelial cell lipid rafts. ..
  64. Almagro S, Durmort C, Chervin Pétinot A, Heyraud S, Dubois M, Lambert O, et al. The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts. Mol Cell Biol. 2010;30:1703-17 pubmed publisher
    ..This mechanism may have functional consequences for endothelium repair in pathological settings...
  65. Faure C, Vico L, Tracqui P, Laroche N, Vanden Bossche A, Linossier M, et al. Functionalization of matrices by cyclically stretched osteoblasts through matrix targeting of VEGF. Biomaterials. 2010;31:6477-84 pubmed publisher
    ..05 Hz). This study qualifies high frequency cyclic stretch as an interesting approach for surfaces activation of deformable biomaterials. ..
  66. Quere I. [Lymphatic system: Anatomy, histology and physiology]. Presse Med. 2010;39:1269-78 pubmed publisher
    ..This article provides an overview of current fundamental knowledge relating to lymphoedema based on both the historical anatomy description and the most recent data about lymphangiogenesis...
  67. Belmokhtar K, Bourguignon T, Worou M, Khamis G, Bonnet P, Domenech J, et al. Regeneration of three layers vascular wall by using BMP2-treated MSC involving HIF-1? and Id1 expressions through JAK/STAT pathways. Stem Cell Rev. 2011;7:847-59 pubmed publisher
    ..Rh-BMP2 by mimicking embryological conditions allowed vascular BM-MSCs differentiation. ..
  68. Estrach S, Cailleteau L, Franco C, Gerhardt H, Stefani C, Lemichez E, et al. Laminin-binding integrins induce Dll4 expression and Notch signaling in endothelial cells. Circ Res. 2011;109:172-82 pubmed publisher
    ..We show that, in endothelial cells, ligation of ?2?1 and ?6?1 integrins induces the Notch pathway, and we disclose a novel role of basement membrane proteins in the processes controlling tip vs stalk cell selection. ..
  69. Moussion C, Girard J. Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules. Nature. 2011;479:542-6 pubmed publisher
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