Experts and Doctors on embryonic stem cells in Germany
Topic: embryonic stem cells
Pfaffeneder T, Hackner B, Truss M, Münzel M, Muller M, Deiml C, et al
. The discovery of 5-formylcytosine in embryonic stem cell DNA. Angew Chem Int Ed Engl. 2011;50:7008-12 pubmed publisher
Ziegenhain C, Vieth B, Parekh S, Reinius B, Guillaumet Adkins A, Smets M, et al
. Comparative Analysis of Single-Cell RNA Sequencing Methods. Mol Cell. 2017;65:631-643.e4 pubmed publisher
..Our quantitative comparison offers the basis for an informed choice among six prominent scRNA-seq methods, and it provides a framework for benchmarking further improvements of scRNA-seq protocols. ..
Ferry L, Fournier A, Tsusaka T, Adelmant G, Shimazu T, Matano S, et al
. Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation. Mol Cell. 2017;67:550-565.e5 pubmed publisher
..These results further elucidate the function of UHRF1, identify a non-histone target of G9a and GLP, and provide an example of a histone mimic that coordinates DNA replication and DNA methylation maintenance. ..
Skamagki M, Correia C, Yeung P, Baslan T, Beck S, Zhang C, et al
. ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors. Nat Cell Biol. 2017;19:1037-1048 pubmed publisher
..Correcting the genomic instability of A-iPSCs will ultimately enhance our ability to produce histocompatible functional tissues from older patients' own cells that are safe for transplantation. ..
Karg E, Smets M, Ryan J, Forne I, Qin W, Mulholland C, et al
. Ubiquitome Analysis Reveals PCNA-Associated Factor 15 (PAF15) as a Specific Ubiquitination Target of UHRF1 in Embryonic Stem Cells. J Mol Biol. 2017;: pubmed publisher
..In summary, we identified novel ubiquitination targets that link UHRF1 to transcriptional regulation and DNA damage response...