Genomes and Genes
Experts and Doctors on drosophila melanogaster in France
Topic: drosophila melanogaster
Publications311 found, 100 shown here
- Gross L, Vicens Q, Einhorn E, Noireterre A, Schaeffer L, Kuhn L, et al. The IRES5'UTR of the dicistrovirus cricket paralysis virus is a type III IRES containing an essential pseudoknot structure. Nucleic Acids Res. 2017;45:8993-9004 pubmed publisher..The IRES5'UTR contains a pseudoknot structure that is essential for proper folding and ribosome recruitment. Overall, our results pave the way for studies addressing the synergy and interplay between the two IRES from CrPV. ..
- Silber J, Le Menn A, Chevillard S, Zider A, Paumard S. The vestigial locus of Drosophila melanogaster is involved in resistance to inhibitors of dTMP synthesis. Mol Gen Genet. 1993;241:42-8 pubmed..Our results indicate a role for the vestigial locus in mediating resistance to inhibitors of dTMP synthesis. ..
- Rauzi M, Lenne P, Lecuit T. Planar polarized actomyosin contractile flows control epithelial junction remodelling. Nature. 2010;468:1110-4 pubmed publisher..Thus, epithelial morphogenesis is not properly reflected by Myosin II steady state distribution but by polarized contractile actomyosin flows that emerge from interactions between E-cadherin and actomyosin networks...
- Couturier L, Vodovar N, Schweisguth F. Endocytosis by Numb breaks Notch symmetry at cytokinesis. Nat Cell Biol. 2012;14:131-9 pubmed publisher..We propose that unequal segregation of Numb results in increased endocytosis in one daughter cell, hence asymmetry of Notch at the cytokinetic furrow, directional signalling and binary fate choice. ..
- Bellaiche Y, Radovic A, Woods D, Hough C, Parmentier M, O Kane C, et al. The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila. Cell. 2001;106:355-66 pubmed..Finally, Baz and the Dlg/Pins complex are required for the asymmetric localization of Numb. Thus, the Dlg/Pins complex responds to Fz signaling to establish planar asymmetry in the pI cell. ..
- Wagner C, Ehresmann C, Ehresmann B, Brunel C. Mechanism of dimerization of bicoid mRNA: initiation and stabilization. J Biol Chem. 2004;279:4560-9 pubmed..Thus, loop IIIa appears to be the driving element of the recognition process. The initial open dimer is then converted into a stable closed dimer, possibly through a kinetically controlled mechanism. ..
- Shi M, Lougarre A, Alies C, Fremaux I, Tang Z, Stojan J, et al. Acetylcholinesterase alterations reveal the fitness cost of mutations conferring insecticide resistance. BMC Evol Biol. 2004;4:5 pubmed..Magnitude of the alterations was related to the allelic frequency in Drosophila populations suggesting that the fitness cost is the main driving force for the maintenance of resistant alleles in insecticide free conditions. ..
- Raisin S, Ruel L, Ranieri N, Staccini Lavenant L, Thérond P. Dynamic phosphorylation of the kinesin Costal-2 in vivo reveals requirement of fused kinase activity for all levels of hedgehog signalling. Dev Biol. 2010;344:119-28 pubmed publisher..Therefore, we propose that the extracellular Hh information is conveyed to an intracellular signal through graded Fu kinase activity. ..
- Docquier F, Randsholt N, Deutsch J, Santamaria P. The 35UZ transposon of Drosophila melanogaster reveals differences in maintenance of transcriptional control between embryonic and larval stages. Int J Dev Biol. 1999;43:275-8 pubmed..These data illustrate how maintenance of gene expression depends on the chromosomal environment and on dynamic interactions between all developmentally regulated enhancers located close to a promoter under PcG control. ..
- Veuille M, Baudry E, Cobb M, Derome N, Gravot E. Historicity and the population genetics of Drosophila melanogaster and D. simulans. Genetica. 2004;120:61-70 pubmed..melanogaster makes up a large panmictic population, whereas D. simulans forms a metapopulation that is divided into smaller demes. ..
- Arquier N, Leopold P. Fly foie gras: modeling fatty liver in Drosophila. Cell Metab. 2007;5:83-5 pubmed..A recent study in Drosophila (Gutierrez et al., 2007) reveals a novel role in regulating lipid metabolism for specialized cells called oenocytes that present striking functional similarities to mammalian hepatocytes. ..
- Ayyaz A, Giammarinaro P, Liegeois S, Lestradet M, Ferrandon D. A negative role for MyD88 in the resistance to starvation as revealed in an intestinal infection of Drosophila melanogaster with the Gram-positive bacterium Staphylococcus xylosus. Immunobiology. 2013;218:635-44 pubmed publisher..Thus, we have uncovered a novel function of MyD88 in the regulation of metabolism that appears to be independent of its known roles in immunity and development. ..
- Girardot F, Lasbleiz C, Monnier V, Tricoire H. Specific age-related signatures in Drosophila body parts transcriptome. BMC Genomics. 2006;7:69 pubmed..This work also emphasizes the need for such experiments to reveal in greater detail the consequences of the transcriptional modifications induced by aging regulatory pathways. ..
- Busseau I, Pelisson A, Bucheton A. Characterization of 5' truncated transposed copies of the I factor in Drosophila melanogaster. Nucleic Acids Res. 1989;17:6939-45 pubmed..We discuss possible mechanisms of production of such modified I elements. ..
- Laval M, Pourrain F, Deutsch J, Lepesant J. In vivo functional characterization of an ecdysone response enhancer in the proximal upstream region of the Fbp1 gene of D. melanogaster. Mech Dev. 1993;44:123-38 pubmed..These results provide the first functional characterization, at the level of the whole organism, using a direct in vivo ecdysone induction assay, of a discrete ecdysone response element. ..
- Ligoxygakis P, Bulet P, Reichhart J. Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila. EMBO Rep. 2002;3:666-73 pubmed..18-Wheeler does not qualify as a pattern recognition receptor of Gram-negative bacteria. ..
- Josse T, Boivin A, Anxolabehere D, Ronsseray S. P element-encoded regulatory products enhance Repeat-Induced Gene Silencing (RIGS) of P-lacZ-white clusters in Drosophila melanogaster. Mol Genet Genomics. 2002;268:311-20 pubmed
- Castella C, Amichot M, Berge J, Pauron D. DSC1 channels are expressed in both the central and the peripheral nervous system of adult Drosophila melanogaster. Invert Neurosci. 2001;4:85-94 pubmed..These results strongly suggest that DSC1 and para channels may have complementary roles, at least in the adult stage. ..
- Jabbari K, Bernardi G. Cytosine methylation and CpG, TpG (CpA) and TpA frequencies. Gene. 2004;333:143-9 pubmed..The implications of these results are discussed. ..
- Hudson C, Yasuo H. A signalling relay involving Nodal and Delta ligands acts during secondary notochord induction in Ciona embryos. Development. 2006;133:2855-64 pubmed..We propose a model whereby laterally produced Nodal acts to specify the secondary notochord precursor both directly in the B-line cells and via Delta2 induction in adjacent A-line cells...
- Fablet M, Rebollo R, Biémont C, Vieira C. The evolution of retrotransposon regulatory regions and its consequences on the Drosophila melanogaster and Homo sapiens host genomes. Gene. 2007;390:84-91 pubmed..Particular attention is paid to much-studied representatives of the Vertebrates and Invertebrates, Homo sapiens and Drosophila melanogaster, respectively, for which high quality sequenced genomes are available. ..
- Istamboulie G, Fournier D, Marty J, Noguer T. Phosphotriesterase: a complementary tool for the selective detection of two organophosphate insecticides: chlorpyrifos and chlorfenvinfos. Talanta. 2009;77:1627-31 pubmed publisher..A bi-enzymatic sensor was designed by immobilizing both B394 and PTE in a polyvinylalcohol matrix. The sensor was shown to be able to discriminate between chlorpyrifos and chlorfenvinfos inhibitions. ..
- Csilléry K, Blum M, Gaggiotti O, Francois O. Approximate Bayesian Computation (ABC) in practice. Trends Ecol Evol. 2010;25:410-8 pubmed publisher..ABC can be a powerful tool to make inferences with complex models if these principles are carefully applied. ..
- Miguel L, Frebourg T, Campion D, Lecourtois M. Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies. Neurobiol Dis. 2011;41:398-406 pubmed publisher..Moreover, our TDP-43 Drosophila models indicate that distinct pathways of TDP-43 toxicity might operate depending on the cell type. ..
- Darboux I, Lingueglia E, Champigny G, Coscoy S, Barbry P, Lazdunski M. dGNaC1, a gonad-specific amiloride-sensitive Na+ channel. J Biol Chem. 1998;273:9424-9 pubmed..We postulate that this channel may participate in gametogenesis and early embryonic development in Drosophila. ..
- Serrano N, Maschat F. Molecular mechanism of polyhomeotic activation by Engrailed. EMBO J. 1998;17:3704-13 pubmed..In vivo, we have also shown that normal polyhomeotic expression depends on extradenticle expression. Moreover, in the absence of Extradenticle, overexpression of Engrailed protein represses polyhomeotic expression. ..
- Raymond V, Hamon A, Grau Y, Lapied B. DmGluRA, a Drosophila metabotropic glutamate receptor, activates G-protein inwardly rectifying potassium channels in Xenopus oocytes. Neurosci Lett. 1999;269:1-4 pubmed..Finally, the A-protomer of PTX reduced the glutamate-induced GIRK currents. This study is the first characterization of an invertebrate mGluR-mediated GIRK currents via a PTX-sensitive G protein. ..
- Dallerac R, Labeur C, Jallon J, Knipple D, Roelofs W, Wicker Thomas C. A delta 9 desaturase gene with a different substrate specificity is responsible for the cuticular diene hydrocarbon polymorphism in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2000;97:9449-54 pubmed..We suggest, therefore, that desat2 might play a control role in the biosynthesis of 5,9 HD hydrocarbons in Tai females and could explain the dienic hydrocarbon polymorphism in D. melanogaster. ..
- Gonzy G, Pokholkova G, Peronnet F, Mugat B, Demakova O, Kotlikova I, et al. Isolation and characterization of novel mutations of the Broad-Complex, a key regulatory gene of ecdysone induction in Drosophila melanogaster. Insect Biochem Mol Biol. 2002;32:121-32 pubmed..Sites were found in big ecdysone inducible puffs, constitutively active small puffs as well as interbands. A complete list of the major sites on all four salivary gland polytene chromosomes of BR-C(+) larvae is presented. ..
- Martin D, Daulny A, Decoville M, Locker D. Mutagenesis analysis of the interaction between the dorsal rel homology domain and HMG boxes of DSP1 protein. J Biochem. 2003;134:583-9 pubmed
- Gravot E, Huet M, Veuille M. Effect of breeding structure on population genetic parameters in Drosophila. Genetics. 2004;166:779-88 pubmed..More generally, this suggests the existence of differential reactions to local environments that might contribute to several genomic differences observed between these species. ..
- Janody F, Treisman J. Actin capping protein alpha maintains vestigial-expressing cells within the Drosophila wing disc epithelium. Development. 2006;133:3349-57 pubmed..Our results suggest that Vestigial specifies the cytoskeletal changes that lead to morphogenesis of the adult wing. ..
- Joly W, Mugat B, Maschat F. Engrailed controls the organization of the ventral nerve cord through frazzled regulation. Dev Biol. 2007;301:542-54 pubmed..These results indicate that Engrailed's function during the segregation of the neuroblasts is crucial for regulating different actors that are later involved in axon guidance. ..
- Cavey M, Rauzi M, Lenne P, Lecuit T. A two-tiered mechanism for stabilization and immobilization of E-cadherin. Nature. 2008;453:751-6 pubmed publisher..Uncoupling stability and mobility of E-cadherin complexes suggests that stable epithelia may remodel through the regulated mobility of very stable adhesive foci. ..
- Segalat L, Perichon R, Bouly J, Lepesant J. The Drosophila pourquoi-pas?/wings-down zinc finger protein: oocyte nucleus localization and embryonic requirement. Genes Dev. 1992;6:1019-29 pubmed..H. Morgan isolated (and lost) mutants in the 1920s. This is the first reported occurrence of a zinc finger protein in the nucleus of the Drosophila oocyte. ..
- Maschat F, Dubertret M, Therond P, Claverie J, Lepesant J. Structure of the ecdysone-inducible P1 gene of Drosophila melanogaster. J Mol Biol. 1990;214:359-72 pubmed..Short stretches of nucleotide sequences similar to sequences located in the 5' regions of other genes expressed in the D. melanogaster fat body were found in the proximal promoter and transcribed region of the P1 gene. ..
- Brun S, Rincheval V, Gaumer S, Mignotte B, Guenal I. reaper and bax initiate two different apoptotic pathways affecting mitochondria and antagonized by bcl-2 in Drosophila. Oncogene. 2002;21:6458-70 pubmed..Finally, we show that the inhibition of apoptosis by bcl-2 is associated with the down-regulation of rpr expression. ..
- Perrin L, Bloyer S, Ferraz C, Agrawal N, Sinha P, Dura J. The leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusions. Mol Cell Biol. 2003;23:119-30 pubmed..These data reveal new properties for the leucine zipper domain and thus might provide new clues to understanding the mechanisms by which AF10 fusion proteins in which the PHD domain is lost might trigger leukemias in humans. ..
- Basset A, Tzou P, Lemaitre B, Boccard F. A single gene that promotes interaction of a phytopathogenic bacterium with its insect vector, Drosophila melanogaster. EMBO Rep. 2003;4:205-9 pubmed..Our results demonstrate a specific interaction between plant pathogens and flies that promote their dissemination. ..
- De Iaco R, Soustelle L, Kammerer M, Sorrentino S, Jacques C, Giangrande A. Huckebein-mediated autoregulation of Glide/Gcm triggers glia specification. EMBO J. 2006;25:244-54 pubmed..These data emphasize the importance of fate determinant cell-specific quantitative regulation in the establishment of cell diversity. ..
- Ayers K, Gallet A, Staccini Lavenant L, Therond P. The long-range activity of Hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum. Dev Cell. 2010;18:605-20 pubmed publisher..Thus, we propose that the overall gradient of Hh is a composite of pools secreted by different routes (apical and basolateral), and that a cellular summation of these components is required for appropriate developmental patterning. ..
- Grenier A, Duport G, Pages S, Condemine G, Rahbe Y. The phytopathogen Dickeya dadantii (Erwinia chrysanthemi 3937) is a pathogen of the pea aphid. Appl Environ Microbiol. 2006;72:1956-65 pubmed..The observed difference in virulence toward apterous and winged aphids may have an ecological impact, and this deserves specific attention in future research...
- Meunier N, Belgacem Y, Martin J. Regulation of feeding behaviour and locomotor activity by takeout in Drosophila. J Exp Biol. 2007;210:1424-34 pubmed..Moreover, application of the JH analog methoprene rescues the phenotype. These results suggest that takeout plays a central role as a feeding regulator and may act by modulating the circulating JH level. ..
- Coiffier D, Charroux B, Kerridge S. Common functions of central and posterior Hox genes for the repression of head in the trunk of Drosophila. Development. 2008;135:291-300 pubmed..We propose that an evolutionary early function of Hox genes was to modify primitive head morphology with novel functions specialising the trunk appearing later on. ..
- Rera M, Monnier V, Tricoire H. Mitochondrial electron transport chain dysfunction during development does not extend lifespan in Drosophila melanogaster. Mech Ageing Dev. 2010;131:156-64 pubmed publisher..Thus, the effects of MRC disruption during development on aging differ between species. We discuss the possible origins of such differences. ..
- Rabinow L, Samson M. The role of the Drosophila LAMMER protein kinase DOA in somatic sex determination. J Genet. 2010;89:271-7 pubmed..We speculate that this loop is part of the evolutionary ancestral sex-determination machinery, based upon evidence demonstrating the existence of an autoregulatory loop involving TRA and TRA2 in several other insect species. ..
- Benbahouche N, Iliopoulos I, Török I, Marhold J, Henri J, Kajava A, et al. Drosophila Spag is the homolog of RNA polymerase II-associated protein 3 (RPAP3) and recruits the heat shock proteins 70 and 90 (Hsp70 and Hsp90) during the assembly of cellular machineries. J Biol Chem. 2014;289:6236-47 pubmed publisher..Interaction of Spag with both Hsp70 and Hsp90 suggests a model whereby R2TP would accompany clients from Hsp70 to Hsp90 to facilitate their assembly into macromolecular complexes. ..
- Fleuriet A. Evolution of natural populations in the Drosophila melanogaster sigma system II. Northern and central France. Genetica. 1990;81:33-41 pubmed..These data may also throw some light on the structure of French wild populations of D. melanogaster which appear to be subdivided into local populations between which gene flow might be low. ..
- Oliver B, Singer J, Laget V, Pennetta G, Pauli D. Function of Drosophila ovo+ in germ-line sex determination depends on X-chromosome number. Development. 1994;120:3185-95 pubmed
- Graba Y, Laurenti P, Perrin L, Aragnol D, Pradel J. The modifier of variegation modulo gene acts downstream of dorsoventral and HOM-C genes and is required for morphogenesis in Drosophila. Dev Biol. 1994;166:704-15 pubmed..We propose that down-stream of pattern-forming genes modulo controls, via chromatin structural changes, genes critical for the process of morphogenesis of several tissue types. ..
- Kerckaert J, Deweindt C, Tilly H, Quief S, Lecocq G, Bastard C. LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas. Nat Genet. 1993;5:66-70 pubmed..8 kb message predominantly in normal adult skeletal muscle and in several NHL carrying 3q27 chromosomal defects. We suggest that it may act as a transcription regulator and play an important role in lymphomagenesis. ..
- Schweisguth F, Gho M, Lecourtois M. Control of cell fate choices by lateral signaling in the adult peripheral nervous system of Drosophila melanogaster. Dev Genet. 1996;18:28-39 pubmed..Finally we address how this intercellular signaling mechanism may be modulated to result in highly reproducible outcomes. ..
- Laurencon A, Gay F, Ducau J, Bregliano J. Evidence for an inducible repair-recombination system in the female germ line of Drosophila melanogaster. III. Correlation between reactivity levels, crossover frequency and repair efficiency. Genetics. 1997;146:1333-44 pubmed..The implications of this biological system in connecting genomic variability and environment may shed new lights on adaptative mechanisms. We propose to call it VAMOS for variability modulation system. ..
- Ortega F, Garcia D, Marty J. Structure-functional effects of ethanol on Drosophila melanogaster acetylcholinesterase probed by kinetic studies with substrate and inhibitors. J Enzyme Inhib. 1999;14:125-49 pubmed..It is proposed that ethanol affects the enzyme reactivity by modifying the conformation of the aromatic gorge containing the active centre and hence, interactions involved in the molecular recognition of substrates and ligands...
- Marin L, Lehmann M, Nouaud D, Izaabel H, Anxolabehere D, Ronsseray S. P-Element repression in Drosophila melanogaster by a naturally occurring defective telomeric P copy. Genetics. 2000;155:1841-54 pubmed..Conversely, a second P-lacZ construct, in which the fusion with lacZ takes place in exon 3 of P, was successfully repressed by NA-P(1A). This suggests that NA-P(1A) repression involves a homology-dependent component. ..
- Meunier N, Ferveur J, Marion Poll F. Sex-specific non-pheromonal taste receptors in Drosophila. Curr Biol. 2000;10:1583-6 pubmed..The fact that tarsal gustatory hairs exhibit a sexual dimorphism that affects the perception of non-pheromonal compounds suggests that sexual identity is more complex than has previously been thought [7,8]. ..
- Allemand E, Dokudovskaya S, Bordonné R, Tazi J. A conserved Drosophila transportin-serine/arginine-rich (SR) protein permits nuclear import of Drosophila SR protein splicing factors and their antagonist repressor splicing factor 1. Mol Biol Cell. 2002;13:2436-47 pubmed..Together, the results imply that the mechanism by which SR proteins are imported to the nucleus is conserved between Drosophila and humans. ..
- Leopold P. Neuronal differentiation: TOR and insulin receptor pathways set the tempo. Cell. 2004;119:4-5 pubmed..A recent study reveals a novel role for these pathways in controlling the timing of neuronal differentiation during Drosophila development, thus allowing a tight coordination between growth and differentiation programs. ..
- de Rosny E, de Groot A, Jullian Binard C, Gaillard J, Borel F, Pebay Peyroula E, et al. Drosophila nuclear receptor E75 is a thiolate hemoprotein. Biochemistry. 2006;45:9727-34 pubmed..The other iron coordination pairs are discussed. We conclude that E75 is a new example of a thiolate hemoprotein and that it may be involved in hormone synthesis regulation. ..
- Grammont M. Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis. J Cell Biol. 2007;177:139-50 pubmed..This provides new evidence that Notch, besides playing a key role in cell differentiation, also controls cell morphogenesis. ..
- Forcet C, Billaud M. Dialogue between LKB1 and AMPK: a hot topic at the cellular pole. Sci STKE. 2007;2007:pe51 pubmed..Thus, LKB1 appears to be a novel class of tumor suppressor that acts as an energy-sensing and polarity checkpoint. ..
- Soustelle L, Roy N, Ragone G, Giangrande A. Control of gcm RNA stability is necessary for proper glial cell fate acquisition. Mol Cell Neurosci. 2008;37:657-62 pubmed publisher..Thus, control of a single RNA half-life is crucial for nervous system differentiation. ..
- Tourmente S, Savre Train I, Berthier F, Renaud M. Expression of six mitochondrial genes during Drosophila oogenesis: analysis by in situ hybridization. Cell Differ Dev. 1990;31:137-49 pubmed..Northern analysis of poly(A)+RNA from ovaries or cultured cells revealed an 1.7 kb extra-mitochondrial RNA, which is probably of nuclear origin. ..
- de la Roche Saint Andre C, Bregliano J. Evidence for a multistep control in transposition of I factor in Drosophila melanogaster. Genetics. 1998;148:1875-84 pubmed..Additionally, negative regulation is also exerted downstream of I factor RNA. This differs notably from previous conclusions in which transcription was envisaged as the main level of regulation of the I factor transposition. ..
- Van De Bor V, Giangrande A. Notch signaling represses the glial fate in fly PNS. Development. 2001;128:1381-90 pubmed..Numb, which is asymmetrically localized in the multipotent cell that produces the glial precursor, induces glial cells at the expense of neurons. Thus, a cell-autonomous mechanism inhibits Notch signaling. ..
- Le Bourg E, Fournier D. Is lifespan extension accompanied by improved antioxidant defences? A study of superoxide dismutase and catalase in Drosophila melanogaster flies that lived in hypergravity at a young age. Biogerontology. 2004;5:261-6 pubmed..The greater longevity of male flies that have lived in hypergravity at a young age thus cannot be explained by the activity changes of these major antioxidant enzymes. ..
- Beck Y, Dauer C, Richards G. Dynamic localisation of KR-H during an ecdysone response in Drosophila. Gene Expr Patterns. 2005;5:403-9 pubmed..Such behaviour is most likely a conserved characteristic of hormonal responses. ..
- Jolly C, Lakhotia S. Human sat III and Drosophila hsr omega transcripts: a common paradigm for regulation of nuclear RNA processing in stressed cells. Nucleic Acids Res. 2006;34:5508-14 pubmed
- Merabet S, Saadaoui M, Sambrani N, Hudry B, Pradel J, Affolter M, et al. A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax. Proc Natl Acad Sci U S A. 2007;104:16946-51 pubmed
- Ghiglione C, Devergne O, Cerezo D, Noselli S. Drosophila RalA is essential for the maintenance of Jak/Stat signalling in ovarian follicles. EMBO Rep. 2008;9:676-82 pubmed publisher..As a result, border-cell assembly and migration as well as the polarization of the oocyte are defective. Thus, RalA is required in organizing centres to control proper patterning and migration in vivo. ..
- Hampoelz B, Azou Gros Y, Fabre R, Markova O, Puech P, Lecuit T. Microtubule-induced nuclear envelope fluctuations control chromatin dynamics in Drosophila embryos. Development. 2011;138:3377-86 pubmed publisher..Thus, the NE is a dynamic organelle, fluctuations of which increase chromatin dynamics. We propose that such mechanical regulation of chromatin dynamics by MTs might be important for gene regulation...
- Niehus S, Giammarinaro P, Liegeois S, Quintin J, Ferrandon D. Fly culture collapse disorder: detection, prophylaxis and eradication of the microsporidian parasite Tubulinosema ratisbonensis infecting Drosophila melanogaster. Fly (Austin). 2012;6:193-204 pubmed publisher..These cures only work on stocks that have not become too weak to withstand the procedures...
- Paredes J, Herren J, SchÃ¼pfer F, Marin R, Claverol S, Kuo C, et al. Genome sequence of the Drosophila melanogaster male-killing Spiroplasma strain MSRO endosymbiont. MBio. 2015;6: pubmed publisher..melanogaster, which is emerging as a model of endosymbiosis. ..
- Vincent A, Kejzlarova Lepesant J, Segalat L, Yanicostas C, Lepesant J. sry h-1, a new Drosophila melanogaster multifingered protein gene showing maternal and zygotic expression. Mol Cell Biol. 1988;8:4459-68 pubmed
- Yeramian E, Jones L. GeneFizz: A web tool to compare genetic (coding/non-coding) and physical (helix/coil) segmentations of DNA sequences. Gene discovery and evolutionary perspectives. Nucleic Acids Res. 2003;31:3843-9 pubmed
- Ohayon D, Pattyn A, Venteo S, Valmier J, Carroll P, Garces A. Zfh1 promotes survival of a peripheral glia subtype by antagonizing a Jun N-terminal kinase-dependent apoptotic pathway. EMBO J. 2009;28:3228-43 pubmed publisher..We propose that, in cells such as SPG that do not undergo self-renewal and survive long periods, transcriptional control of RHG-motif gene expression together with fine tuning of JNK signalling is crucial for cell survival. ..
- Wagner C, Palacios I, Jaeger L, St Johnston D, Ehresmann B, Ehresmann C, et al. Dimerization of the 3'UTR of bicoid mRNA involves a two-step mechanism. J Mol Biol. 2001;313:511-24 pubmed..This suggests that the stabilizing interactions that are formed during the second step of the dimerization process might represent crucial elements for Staufen recognition and localization. ..
- Aulner N, Monod C, Mandicourt G, Jullien D, Cuvier O, Sall A, et al. The AT-hook protein D1 is essential for Drosophila melanogaster development and is implicated in position-effect variegation. Mol Cell Biol. 2002;22:1218-32 pubmed..We propose that the AT-hook D1 protein nucleates heterochromatin assembly by recruiting specialized transcriptional repressors and/or proteins involved in chromosome condensation. ..
- Szuplewski S, Kottler B, Terracol R. The Drosophila bZIP transcription factor Vrille is involved in hair and cell growth. Development. 2003;130:3651-62 pubmed..The phenotypes observed are consistent with the hypothesis that vri is required for normal cell growth and proliferation via the regulation of the actin cytoskeleton. ..
- Déjardin J, Cavalli G. Chromatin inheritance upon Zeste-mediated Brahma recruitment at a minimal cellular memory module. EMBO J. 2004;23:857-68 pubmed..Thus, epigenetic inheritance of active chromatin states involves the recruitment of multiple cooperative chromatin-modifying complexes at closely spaced but distinct sites within a CMM. ..
- Menozzi P, Shi M, Lougarre A, Tang Z, Fournier D. Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster populations. BMC Evol Biol. 2004;4:4 pubmed..The presence of several alleles in natural populations, offering various resistance to carbamate and organophosphate compounds will complicate the establishment of resistance management programs. ..
- Lachaise D, Silvain J. How two Afrotropical endemics made two cosmopolitan human commensals: the Drosophila melanogaster-D. simulans palaeogeographic riddle. Genetica. 2004;120:17-39 pubmed
- Vanolst L, Fromental Ramain C, Ramain P. Toutatis, a TIP5-related protein, positively regulates Pannier function during Drosophila neural development. Development. 2005;132:4327-38 pubmed..The results suggest that Tou and Iswi may belong to a complex that directly regulates the activity of Pnr and Chip during enhancer-promoter communication, possibly through chromatin remodelling. ..
- Flici H, Erkosar B, Komonyi O, Karatas O, Laneve P, Giangrande A. Gcm/Glide-dependent conversion into glia depends on neural stem cell age, but not on division, triggering a chromatin signature that is conserved in vertebrate glia. Development. 2011;138:4167-78 pubmed publisher..Thus, glial differentiation needs low levels of histone acetylation, a feature shared by vertebrate glia, calling for an epigenetic pathway conserved in evolution. ..
- Götze M, Dufourt J, Ihling C, Rammelt C, Pierson S, Sambrani N, et al. Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch. RNA. 2017;23:1552-1568 pubmed publisher..Binding of Me31B and Tral was also SRE-dependent, but their amounts were proportional to the length of the RNA and equimolar to each other. We suggest that "coating" of the RNA by a Me31B•Tral complex may be at the core of repression. ..